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Immunoglobulin in Medical News

MEDEX Global Group Cautions: Beware of Rabies When Abroad

... of rabies vaccines and the human or equine rabies immunoglobulin (RIG) recommended by the World Health ... exists in the countries where the vaccine and immunoglobulin are most needed," according to Dr. Henry ... they will not need the expensive and scarce immunoglobulin (RIG) if they are bitten by an animal in a rabies ...

NYU School of Medicine pathology researchers solve another mystery in B lymphocyte development

... Immunology ahead of the June 2009 print issue has found that homologous immunoglobulin (lg) alleles pair up in the nucleus at stages that coincide with V(D)J ... and ATM Coordinate Monoallelic Recombination and Nuclear Positioning of immunoglobulin Loci," researchers found that RAG-mediated cleavage occurs on one allele ...

Scott Miller and Company Premieres "A CALL TO ARMS 2009 EDITION" at the Camelot Theaters in Palm Springs

... the anthrax vaccine, when the immune system creates Furin-sequestering immunoglobulin gamma (IgG) antibodies in response to the BioThrax™ anthrax ... damage due to the sequestering of the FURIN activator protein by the immunoglobulin gamma (IgG) antibody, which can be created as an immune response to ...

Studies Ignite Hope for Long-Acting Allergy Vaccines

... in the bloodstream. People with allergies produce an antibody called immunoglobulin E, which sets off a cascade of chemicals to fend off a perceived allergen, ... symptoms that people experience. Another antibody in blood, called immunoglobulin G, fights infection. "What the study showed was that the G antibodies ...

Immunoglobulin Can Predict Some Diabetic Complications

... excretion of IgM foretells serious cardiovascular issues: study FRIDAY, Aug. 7 (HealthDay News) -- Swedish researchers say that immunoglobulin M (IgM) is a reliable predictor of cardiovascular complications in people with type 1 diabetes who have diabetic nephropathy (DN) -- kidney damage ...

Bcl6 gene sculpts helper T cell to boost antibody production

... cell proliferation and antibody development. "In germinal centers, the B cells not only proliferate but they also undergo hypermutation in their immunoglobulin genes so they can produce a diverse class of antibodies," Dong said. "These mutations also allow production of antibodies with stronger affinity for ...

FDA Approves VITROS(R) Anti-HCV Assay for Use On VITROS 5600(R) Integrated and VITROS 3600(R) Immunodiagnostic Systems

... experience any symptoms(2). The VITROS((R)) Anti-HCV assay is an in vitro diagnostic immunoassay for the qualitative detection of immunoglobulin G antibody to hepatitis C virus (anti-HCV) in human serum and plasma. It can be run with excellent precision, sensitivity, low sample volume ...

New Alzheimer's Treatment Could Be on the Horizon

... diseases might also help ward off Alzheimer's disease, new research suggests. Researchers looked at the association between the use of intravenous immunoglobulin (IVIg) and the occurrence of Alzheimer's. "IVIg has been used safely for more than 20 years to treat other diseases but is thought to have an ...

Novel DNA vaccine leads to kidney damage prevention in systemic lupus erythematosus models

... 9. At day 16, mice were induced with experimental SLE. Serum samples were collected at day 0 and then monthly for analysis of autoantibodies and immunoglobulin levels. Serum autoantibodies were tested by immunoprecipitation and ELISA. Proteinuria (excessive protein in the urine) was assessed monthly using ...

New Jefferson study may redefine how a chronic auto-immune disease is diagnosed

... a more protracted chronic course. Treatment for CIDP includes corticosteroids such as prednisone, plasmapheresis (plasma exchange) and intravenous immunoglobulin (IVIg). IVIg may be used even as a first-line therapy. Immunosuppressant drug therapy may be effective in patients who fail standard therapy. ...

CUHK Releases Results of 'Survey on Toddler Health in Hong Kong'

... pay more attention to their development needs," Mr. Schipper said. "Clinical trials show that Nestle's new Probiotics Bifidus BL enhances levels of immunoglobulin A (IgA), which is crucial for boosting toddlers' immunity and improving their gastrointestinal environment as well as bowel habits. Nestle's EXCEL is ...

Mach One Corporation Announces Hand Carried Product as a Potential Solution to Swine Flu (H1N1) Virus

... slow the frequency of the virus in the environment." Dr. Nash continued, "When blockage of the attachment of the virus is the objective, the immunoglobulin package is supplied to humans prior to exposure or immediately after an outbreak. The substantial prevention of viruses in the nasal pharyngeal ...

New data analysis shows possible link between childhood obesity and allergies

... In this study, the researchers analyzed data from 4,111 children and young adults aged 2-19 years of age. They looked at total and allergen-specific immunoglobulin E (IgE) or antibody levels to a large panel of indoor, outdoor and food allergens, body weight, and responses to a questionnaire about diagnoses of ...

Exposure to Peanuts May Build Tolerance to Allergy

... the treatment and eat peanuts, the researchers said. When the researchers tracked immunologic changes -- specifically levels of an antibody called immunoglobulin E, which the body makes in response to allergens -- they found the levels had declined to nearly nothing at the end of the trial. "I think what ...

Studies show children can complete treatment for peanut allergies and achieve long-term tolerance

... Doctors keep tabs on any potential changes in their immune system via skin, blood and immune studies. One of the tests used in the study looks at immunoglobulin E (IgE), a protein the body makes in response to peanut allergens. "If you have it, you're likely allergic, if you don't, you aren't," explained ...

Number of cardiovascular risk factors could determine safety of intravenous gammaglobulin treatment

... the presence of cardiovascular risk factors as an indicator of how likely it is that elderly, hospitalized patients who receive intravenous immunoglobulin (IVIg) treatment will have a stroke or heart attack. An advance copy of the study appears online this week in the Journal of Neurology , the ...

Landmark Rh Immune Globulin Celebrates 40 Years of Saving Babies' Lives

... due to the risk of a hemolytic reaction. DESCRIPTION RhoGAM and MICRhoGAM Rho(D) Immune Globulin (Human) are sterile solutions containing immunoglobulin G (IgG) anti-D (anti-Rh) for use in preventing Rh immunization. They are manufactured from human plasma containing anti-D. A single dose of RhoGAM ...

Rockefeller University's Center for Clinical and Translational Science funds 18 new pilot studies

... Laboratory of Molecular Immunology, to identify antibodies for a possible immune-based HIV vaccine, employing B cell lymphocyte sorting and immunoglobulin cloning techniques. Jonathan Schmitz, biomedical fellow, Vincent A. Fischetti's Laboratory of Bacterial Pathogenesis and Immunology, to mine the ...

The miseries of allergies just may help prevent some cancers, study finds

... by shedding foreign particles from the body. Some of those particles, he said, might be carcinogenic or carry carcinogens. "The idea is that the immunoglobulin E system (which is widespread among mammals) and its associated allergy symptoms serve a common prophylactic function," Sherman said, "namely ...

UNC researcher aims to 'unmask' cancer cells to trigger body's immune system

... from the body when delivered via IV. Cho plans to add a molecule to the nucleic acid that will allow it to latch on to a class of proteins called IgG immunoglobulin that occur naturally in the body. "We will ask the IgG antibodies to carry the bacteria-derived nucleic acid as a guest throughout the body," Cho ...

Peter Ell receives SNM's Georg Charles de Hevesy Nuclear Pioneer Award

... flow in the brain and indicate the existence of heart disease and inflammatory bowel disease. Along with other researchers, Ell initiated the use of immunoglobulin G (human IgG), a type of antibody that circulates in the blood and recognizes foreign particles that might be harmful, as well as iodobenzamide ...

Haemacure Raises $7.8 Million and is Fully Funded Beyond First-Patient-In-Clinic

... strategic partnerships for the development of the proteins it has identified in one of its two plasma fractions: albumin, alpha-1 anti-trypsyn, immunoglobulin and plasminogen. About Haemacure Haemacure Corporation is a specialty bio-therapeutics company developing high-value human plasma-derived protein ...

Bacterial Infection May Boost SIDS Risk

... editorial pointed out, the number of SIDS cases peaks at 8 weeks to 10 weeks of age. That's a time-frame coinciding with blood concentrations of immunoglobulin that protect newborns against bacterial infections. "This is just at the point that antibodies that go across the placenta -- from mom to baby -- ...

China Biologic Products Announces Approval for the Relocation of Fang Cheng Plasma Collection Station and for the Procurement of Excess Clinical Plasma

... to hospitals and other health care facilities in China. The Company's human albumin products are mainly used to increase blood volume and its immunoglobulin products are used for the treatment and prevention diseases. Safe Harbor Statement This release may contain certain ''forward-looking statements" ...

Biotest Pharmaceuticals Corporation Responds to Orphan Drug Act Announcement

... used in the prevention of hepatitis B. Biotest Pharmaceuticals also is currently working to develop additional products including a polyvalent immunoglobulin (IVIG, Phase III) and Civacir(R) (Phase IIb), for the prevention of hepatitis C in liver transplant patients. Biotest Pharmaceuticals was formed in ...

Researchers find cause of severe allergic reaction to cancer drug

... receiving cetuximab in the Northeast region of the United States suffered such reactions. Anaphylactic reactions are typically triggered by immunoglobulin E (IgE) antibodies, which the immune system produces after being sensitized by prior exposure to an allergen, a normally harmless substance that in ...

Novel method to reveal drug targets

... the proteins together, as in a small scrap of Velcro." The team identified previously undescribed interactions in a class of proteins called the immunoglobulin superfamily: this group of proteins shares properties that are important to allow cells to respond to their environment, talk to one another and ...

NIST, NCI, SAIC partner on new method for detecting HER2 breast cancer

... expensive treatment that cant help them. In a paper in the International Journal of Cancer,* the NIST-NCI-SAIC research team found that chicken immunoglobulin Y (IgY) antibody created against the HER2 protein could be tagged with quantum dot (tiny, intense and tunable sources of colorful light) to more ...

Sanofi Pasteur Enters Agreement With Crucell for Next-Generation Biologicals Against Rabies

... legacy with innovative treatments." Crucell has developed a combination of two rabies MAbs that has shown favorable results comparable to current immunoglobulin products in preclinical trials. Phase I clinical trials demonstrated that the MAb-based product is well tolerated, provides the expected immediate ...

Parents' Smoking Boosts Child's Allergy Risk

... 2 years and 4 years. In addition, the researchers collected blood samples from more than 2,500 children at the age of 4 to check for the presence of immunoglobulin E (IgE), which is released by the immune system in response to allergens. High levels of IgE indicate sensitization to allergens. About 8 percent ...

Thalidomide Added to Standard Therapy Prolongs Overall Survival in Newly Diagnosed Multiple Myeloma Patients Over Age 75

... called immunoglobulins that fight infection and disease. However, most patients with multiple myeloma have cells that produce a form of immunoglobulin called paraprotein (or M protein) that does not benefit the body. In addition, the malignant plasma cells replace normal plasma cells and other white ...

JCI online early table of contents: Dec. 6, 2007

... detailed determinants of prognosis in individuals with UM B-CLL, something that might help determine the clinical management of patients. TITLE: immunoglobulin diversity gene usage predicts unfavorable outcome in a subset of chronic lymphocytic leukemia patients AUTHOR CONTACT: Diane F. Jelinek Mayo ...

Rigel R788 Raises Platelet Counts in Immune Thrombocytopenic Purpura (ITP) Patients in Phase 2 Study

... R788 for 20 weeks of the study. For those two patients, this marked the first time in 10 years that each achieved prolonged avoidance of intravenous immunoglobulin G injections. Overall these patients were highly refractory with most having failed several other therapies, 10 had failed splenectomy and 5 were ...

AAAAI: Early Day Care Attendance May Protect Infants From Later Developing Asthma, From the Journal of Allergy and Clinical Immunology

... (AAAAI). Janet Rothers, MS, and colleagues examined the relationship between the age at which day care attendance begins and the amount of immunoglobulin E (IgE) in a child's blood. IgE is an antibody produced by the immune system and an indicator of allergic sensitivity. Researchers found: * ...

New Asthma Guidelines Stress Disease Control

... are geared to people 12 and older with severe asthma. These steps include the addition of the drug omalizumab, a monoclonal antibody that targets immunoglobulin E, which is associated with allergic reactions, Busse said. The guidelines also stress the importance of teaching patients to self-monitor and ...

Lactococcus Strain may Offer End to Food Allergies

... was reduced significantly, while blood levels of antigen-specific immunoglobulin E (IgE) - an antibody subclass capable of initiating the most powerful ... also significantly reduced. Moreover, production of antigen-specific immunoglobulin A (IgA) in the gut "These results suggest that a microorganism ...

Inflammation can Lead to Cancer

... cancer-promoting pathway. Part of the receptor for the antibody known as immunoglobulin appears to be involved, Coussens said. The good news, she adds, is ... there is no evidence and no likelihood that periodic booster shots of the immunoglobulin antibody, or even blood transfusions from someone with precancerous tissue ...

Drug Meant to Heal Turns ‘heel’ and Hars

... Co. Ltd. had committed "illegal behavior" in the production of its immunoglobulin drug and that users had tested positive to "Hepatitis C antibodies". ... Health Ministry, quoted experts as saying that the plasma used to make the immunoglobulin drug might have contained either the hepatitis C virus or its antibodies. ...

Infants Need to Be Vaccinated For Hepatitis B

... harmful and beneficial, have been researched with regard to hepatitis B immunoglobulin and hepatitis B vaccines for the hepatitis B surface antigen in newborn ... a combination of both, along with immunoglobulin. The combination with the immunoglobulin was seen to be the better and more effective alternative. Further research ...
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