Are imaging features of hepatic angiomyolipoma related to its clinical setting?
... of 10 patients (three male and seven female) with hepatic
angiomyolipoma, with a mean age of 55.1 years ... Of these patients, dynamic contrast CT showed hepatic
angiomyolipoma as a hypervascular mass with ... in six sporadic cases, and multiple, small hepatic
angiomyolipomas, with or without a fat component ...
Is RTA a new potential option for the treatment of hydatid cysts?
RTA was performed on 17 cysts (9 hepatic
and 8 pulmonary), and was followed by pathology ... with a 100% success rate was seen in both hepatic
(9/9) and lung cysts (8/8). A layer of host ... remained attached to the pericystium both in hepatic
and lung cysts, with small and focal de novo ...
New HIV Study Shows That Large Numbers of Women and People of Color Can Be Successfully Enrolled In U.S. HIV Clinical Studies
... liver function abnormalities, including severe hepatic
Use in Specific Populations
impairment: PREZISTA/r is not recommended for use in patients with severe hepatic
impairment. There are no pharmacokinetic or ...
Study examines dietary influences of liver disease
... that dietary factors influence the development of hepatic
steatosis and its progression to more severe ... are the most important known risk factors for hepatic
steatosis. Also, dietary lipids may directly ... relevant dietary factors are more likely to have hepatic
effects through obesity-related fatty liver ...
Hyperion Therapeutics Raises $60 Million Series C
... for UCD as well as a Phase II study in low grade hepatic
Concurrent with the Series C ... in the treatment of both urea cycle disorders and hepatic
encephalopathy," said Daniel Perez of Bay City ... in brain damage, coma, and/or death.
Hyperion Therapeutics Announces Results of Phase I Study in Patients With Liver Cirrhosis
... - Company preparing to initiate phase II trial in hepatic
SOUTH SAN FRANCISCO, ... of HPN-100 administered orally to subjects with hepatic
impairment and cirrhosis and to subjects with normal hepatic
function. A total of thirty-two subjects were ...
AZOR(R) Receives FDA Approval as First-Line Treatment for High Blood Pressure
... of the olmesartan medoxomil component.
Since amlodipine is extensively ... is 56 hours in patients with severely impaired hepatic
function, caution should be exercised when administering AZOR to patients with severe hepatic
There was a ...
Video: FDA approves Exforge HCT(R) - the Only High Blood Pressure Treatment to Combine Three Medications in a Single Pill
... be used with caution in patients with severe hepatic
impairment and should be used with care in patients with mild-to-moderate hepatic
impairment, including patients with biliary ... Avoid use of EXFORGE HCT in patients with severe hepatic
impairment. In patients with ...
JCI online early table of contents: April 13, 2009
... a spectrum of disease states, beginning with hepatic
steatosis, which leads to steatohepatitis, ... new insight into the mechanisms underlying hepatic
steatosis in obese insulin-resistant rodents. ... protein SREBP-1c, which is intimately involved in hepatic
lipogenesis (and ...
FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia
Isolated cases of significant hepatic
dysfunction and hepatic
failure have been reported in patients being ... should be monitored for evidence of worsening hepatic
function. Adverse events may occur after the ...
Long-term L-carnitine supplementation prevents development of liver cancer
... factor and should be viewed as a mechanism in hepatic
carcinogenesis, and that long-term L-carnitine ... and/or carnitine deficiency during induction of hepatic
The research team by ... mechanisms whereby carnitine deficiency provokes hepatic
carcinogenesis. (2) to understand the ...
Cathepsin B increases apoptosis in fulminant hepatic failure
... necrosis is the main feature of fulminant hepatic
failure, but increasing evidence implicates a ... is involved in the pathogenesis of fulminant hepatic
failure. To ascertain its pathogenic role in hepatic
failure, the research examined the protective ...
Prescription Copay Assistance for Patients taking Gleevec or Tasigna for Philadelphia chromosome-positive Chronic Myelogenous Leukemia (Ph+ CML)
... taking dose. Use with caution in patientswith hepatic
impairment. ECGs should be obtained to monitor ... CYP3A4 inhibitors. Use caution in patients with hepatic
impairment. Obtain ECGs at baseline, seven days ...
Liver function abnormality
Serum bilirubin and hepatic
The use of Tasigna may result in ...
Liver Cirrhosis May Also Harm Brain, Heart
... have heart-rate issues and a condition known as hepatic
(liver) encephalopathy, which occurs when an ... amount of unfiltered toxins reaches the brain. hepatic
encephalopathy can affect both physical and ... found strong ties between heart rate issues and hepatic
encephalopathy. A person's level of inflammatory ...
PREZISTA(R) Now Available for Pediatric Patients Six Years of Age and Older as part of HIV Combination Therapy
... liver function abnormalities, including severe hepatic
Post-marketing cases ... not recommended for use in patients with severe hepatic
impairment. There are no pharmacokinetic or safety data available in patients with severe hepatic
PREZISTA should be used ...
PEGASYS(R) Proven Effective as Hepatitis C Treatment for Latino Patients, According to Article in The New England Journal of Medicine
... any of its components, autoimmune hepatitis, and hepatic
decompensation (Child-Pugh score greater than 6; ... treatment. PEGASYS is also contraindicated in hepatic
decompensation with Child-Pugh score greater than ... C (CHC) patients with cirrhosis may be at risk of hepatic
decompensation and death when treated with alpha ...
May hepatic granulomas be part of the histological spectrum of chronic hepatitis C?
... While older large series of patients with hepatic
granulomas have found sarcoidosis and tuberculosis to be the most common causes of hepatic
granulomas, recent works have noted some patients with chronic hepatic
A potential drug for ischemia/reperfusion related liver injury
injury caused by ischemia/reperfusion (I/R) has ... effect of resveratrol against I/R-induced hepatic
injury, using biochemical and histological ... group. Malondialdehyde levels and the hepatic
injury score decreased, while superoxide ...
New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes
... is needed for patients with mild to moderate hepatic
insufficiency or in patients with mild renal ... syndrome [see Warnings and Precautions (5.3); hepatic
... from pancreatic alpha cells, leading to reduced hepatic
glucose production. By increasing and prolonging ...
Mayo Clinic's new imaging technology accurately identifies a broad spectrum of liver disease
... highly accurate in detecting moderate-to-severe hepatic
fibrosis even with the variety in age, types of ... with a needle, can underestimate the degree of hepatic
fibrosis about 20 to 30 percent of the time ... changes can help stop the progression of hepatic
fibrosis to liver cirrhosis and liver failure, ...
New study indicates that exercise prevents fatty liver disease
... activates specific precursors known to promote hepatic
steatosis," said Jamal Ibdah, professor of ... signs of factors responsible for promoting hepatic
steatosis. In the animals tested immediately at ... of voluntary running, there were no signs of hepatic
"Physical activity prevented fatty ...
Low-carb diets alter glucose formation by the liver
... study shows that a low-carbohydrate diet changes hepatic
energy metabolism. When carbohydrates are ... has been difficult.
To better understand hepatic
energy production and glucose formation among ... Medical Center measured the sources of hepatic
glucose and TCA cycle flux in weight-stable ...
An effective strategy for inhibition of cirrhosis
... Medicin Qianggan-Rongxian decoction can inhibit hepatic
fibrosis resulted from chronic liver injure, ... and type IV collagen are good serum markers of hepatic
fibrosis. In this study, the serum contents of ... decrease serum levels of ALT and AST in rats with hepatic
injury caused by DMN. It indicates that ...
Stem cells from umbilical cord used in the treatment of hepatic diseases
... be an appropriate therapy for the treatment of hepatic
diseases such as hepatitis, and therefore mean an ... cord blood cells (HUCBCs) can be useful for hepatic
regenerative medicine, as they can nest in the ... to rat in which HUCBCs were injected through the hepatic
portal vein of rats with hepatitis caused by ...
How to diagnose peliosis hepatis
... upper right abdominal pain for four months. After hepatic
lobectomy of the right lobe, histopathological ... hypodensity lesion in segment VIII was peliosis hepatic
and gumma, respectively.
This study, performed ... the differential diagnosis of an atypical focal hepatic
lesion. Besides looking into the patient's ...
New findings: The anti-fibrotic mechanism of plant extract Cpd 861
... In human hepatic
stellate cells, the key cells involved in both ... in the World Journal of Gastroenterology.
fibrosis, which can lead to portal hypertension ... collagens) is the major pathogenic feature in the hepatic
fibrosis process. Although remarkable progress ...
Antipodean Pharmaceuticals Announces Results of Phase 2 Study of Lead Compound MitoQ(R)
... interventions such as MitoQ,
which block either hepatic
necroinflammation or fibrogenesis."
"In the ... Targeted antioxidants can reduce the hepatic
oxidative damage that is
induced by viral ... (mitoquinone
mesylate), for the treatment of hepatic
inflammatory disorders caused by
oxidative stress ...
Researchers study new drug and indications for heated chemotherapy treatment
... of IPHC in patients with peritoneal cancer and hepatic
metastases (HM), or liver cancer that has ... that patients with peritoneal carcinoma and hepatic
metastases undergoing cytoreductive surgery and ... In select patients with peritoneal carcinoma and hepatic
metastases, cytoreductive surgery and IPHC may ...
How to effectively avoid many common complications and liver damage in bile duct exploration?
... surgery. In operations combining laparoscopic hepatic
left lateral lobectomy with fiber ... Fu Zhou General Hospital performed laparoscopic hepatic
left lateral lobectomy combined with fiber ... complications.
In this research, laparoscopic hepatic
left lateral lobectomy combined with fiber ...
Hyperion Therapeutics Announces Enrollment of First Patient in Phase 2 Clinical Trial in Patients With Hepatic Encephalopathy
... medical need in the treatment of hepatic
encephalopathy," said Roger
Williams M.D., ... of this multi-factorial disease process."
encephalopathy (HE) is a serious, progressive and ...
New IDSA Clinical Practice Guidelines Recommend NOXAFIL(R) (Posaconazole) for Antifungal Prophylaxis in Certain High-Risk Patients
... clinical trials,
there were infrequent cases of hepatic
reactions (e.g., mild to moderate
elevations in ... and/or
clinical hepatitis). Rarely, more severe hepatic
cholestasis or hepatic
failure including fatalities were reported ...
An emerging candidate for protecting patients from liver injury after abdomen surgery
... Ginsenosaide Rb1 (R1) is able to prevent hepatic
microcirculatory disturbance and subsequent liver ... pills prevent gut ischemia/reperfusion-induced hepatic
microvascular dysfunction in rats fed ethanol ... This enables a dynamic examination of the hepatic
microcirculatory parameters under investigation ...
JCI online early table of contents: Jan. 10 2008
... by a condition known as either fatty liver or hepatic
steatosis, which is the accumulation of fat in ... copies of the Ppara gene developed severe hepatic
steatosis followed by HCC. However, neither ... functional copies of the Ppara gene developed hepatic
steatosis and HCC. Consistent with the idea that ...
MRI techniques evolving towards better assessment of liver fibrosis
... way to determine the existence and extent of hepatic
fibrosis. It could eventually help the ... ).
Currently, the best way to assess hepatic
fibrosis is liver biopsy; however, it is an ... imaging have shown promise for detecting hepatic
fibrosis, though they require further refinement. ...
Who is the arch-criminal in the development of hepatopulmonary syndrome?
... dilatations that are often associated with severe hepatic
disease. HPS occurs in 15-20% of patients with ... and severity of HPS and the degree of hepatic
dysfunction, and explored how intestinal ... deterioration between the lung function and the hepatic
function in the cirrhotic rats. This indicated ...
High-fat diet makes mice susceptible to liver injury
... to obesity, can range in severity from simple hepatic
steatosis to nonalcoholic steatohepatitis (NASH) ...
Tregs have recently emerged as a key player in hepatic
immune regulation, so researchers, led by Xiong ... were fed a normal diet.) They examined the mices hepatic
lymphocyte population by flow cytometry. The ...
Video and Photo: Tasigna(R) Receives US Approval Providing New Hope to Chronic Myeloid Leukemia Patients With Resistance or Intolerance to Existing Therapies
... taking dose.
Use with caution in patients with hepatic
impairment. ECGs should be
obtained to monitor ... CYP3A4 inhibitors. Use
caution in patients with hepatic
impairment. Obtain ECGs at baseline, seven
days ... AST/ALT, and alkaline phosphatase. Check hepatic
periodically. Electrolyte ...
Attenuation of NASH by stimulation of free fatty acid metabolism
... MCD diet, when fed to rodents, rapidly produces hepatic
steatosis and steatohepatitis by blocking fatty ... of NASH remains to be defined. In hepatic
steatosis, an excess of non-esterified fatty ... A potential strategy to protect the liver from hepatic
steatosis would involve mechanisms to ...
96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy
Use in Specific Populations
Impairment: INTELENCE should be used with caution in patients with severe hepatic
impairment (Child-Pugh Class C) as pharmacokinetics of INTELENCE have not ...
NUCYNTA(TM) (tapentadol) CII Immediate Release Tablets Now Available for Relief of Moderate to Severe Acute Pain
NUCYNTA(TM) is not recommended in patients with severe renal or hepatic
impairment. NUCYNTA(TM) should be used with caution in patients with moderate hepatic
impairment. Like other drugs with mu-opioid agonist activity, NUCYNTA(TM) ...