Quark Pharmaceuticals Announces Data Indicating Potential Utility of QPI-1007 for Treatment of Glaucoma
... that QPI-1007 prevents progressive retinal ganglion
cell (RGC) loss in an increased ocular pressure ... of QPI-1007 in two additional models of retinal ganglion
cell (RGC) death - induced by optic nerve crush ... vision loss are caused by the death of retinal ganglion
cells. While existing therapeutics are capable of ...
'Cool' New Treatment for Hot Flashes in Breast Cancer Survivors
... of the safety and efficacy of the stellate ganglion
block in 13
breast cancer survivors. It is called ... on
healthy menopausal women that the stellate ganglion
block can effectively
'shut off' these troubling ... over time.
If the effect of the stellate ganglion
block on hot flashes and night
awakenings did not ...
'Cool' new treatment for hot flashes in breast cancer survivors
... study of the safety and efficacy of the stellate ganglion
block in 13 breast cancer survivors. It is called ... on healthy menopausal women that the stellate ganglion
block can effectively shut off these troubling ... over time.
If the effect of the stellate ganglion
block on hot flashes and night awakenings did not ...
Mouse study: Real-time imaging device may improve surgery for congenital colon disease
... does not detect the presence or absence of ganglion
cells themselves. Instead, the spectral signature ... although the entire colon can be involved. ganglion
cells normally stimulate smooth muscle of the ... pathologist looks for the presence or absence of ganglion
cells and other features. But this process may ...
5 Brown faculty elected to world's largest scientific body
... Specifically, he explores structural and functional diversity among the ganglion
cells of the eye, the retinal neurons that communicate directly with the brain. Current research focuses on one very unusual type of ganglion
cell that senses light directly. These neurons drive reflexive responses ...
Blind humans lacking rods and cones retain normal responses to non-visual effects of light
... mammals have an additional light-sensitive photoreceptor in the retinal ganglion
cell layer (pRGCs) that is directly sensitive to light and is primarily ... effects were maximal in response to wavelengths of light that the retinal ganglion
cells respond best to, and not the wavelength that the visual system ...
Growth factor TGF-B helps maintain health of retinal blood vessels
... tissue, and fluid was leaking out of the vessels, which does not happen when the vessels are functioning properly. These defects led to the death of ganglion
cells (nerve cells in the innermost part of the retina) and a loss of visual function.
According to D'Amore and Walshe, the demonstration of the ...
Experts examine causes, treatment and prevention of glaucoma
... Although scientists know progressive degeneration of retinal ganglion
cells and their axons is the primary cause of glaucoma, researchers have yet to identify a way to stop or prevent the degeneration.
The challenge ...
Protein Might One Day Prevent Blindness
... call neuro-protective, in that it has protective benefits on both the photoreceptor layer that gets damaged in macular degeneration as well as on the ganglion
cell layer which is damaged by glaucoma. So this finding could actually turn out to be a major accomplishment, affecting a lot of patients down the ...
Quark Pharmaceuticals to Present at the 20th Annual Piper Jaffray Health Care Conference
... having a novel, proprietary structure covered by Quark's intellectual property. Data has validated its neuroprotective effects on dying retinal ganglion
cells, a cause of blindness and glaucoma.
About Quark Pharmaceuticals, Inc.
Quark Pharmaceuticals, Inc. is a development-stage ...
Different processes govern sight, light detection
... ) and in the May 1 print issue, Hattar and colleagues reported that they genetically modified mice so that a particular set of retinal ganglion
cells cells that receive input from the rods and cones of the animals eyes and send information to the brain no longer functioned.
The mice ...
Scientific poster abstracts from the 24th annual meeting of the American Academy of Pain Medicine
Perils of Depomedrol Injections into the Vertebral ArteryAn Animal Study
Transsacrococcygeal Approach to ganglion
Impar Block for Management of Chronic Perineal Pain: A Prospective Observational Study.
Methylnaltrexone Treatment of Opioid-Induced ...
Upcoming meeting will explore new technologies for glaucoma clinical drug trials
... central vision.
Glaucoma is a complex group of neurodegenerative diseases that arises from progressive damage to the optic nerve and retinal ganglion
cells and their axons.
It is one of the four major aging eye diseases, alongside age-related macular degeneration, diabetic retinopathy and ...
Neural Insights Could Bring Better Cochlear Implants
... all the way into the brain," team leader and neuroscientist Robin Davis said in a prepared statement.
"Our studies have revealed that sprial ganglion
auditory neurons possess a rich complexity that is only now beginning to be understood," Davis explained.
In this latest research with mouse ...
GlaxoSmithKline Obtains Exclusive U.S. OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc.
... taking the
highest recommended dose (as measured by total enzyme inhibitory activity).
Vestibulocochlear Wallerian-like degeneration and retinal ganglion
chromatolysis were also seen in dogs treated for 14 weeks at 180 mg/kg/day,
a dose which resulted in a mean plasma drug level (Cmax) similar to ...
Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
... Stein Eye Institute, UCLA, in an accompanying editorial.
Why should IOP fluctuation be damaging" Theories abound about the mechanisms of retinal ganglion
cell damage in glaucoma, but no single cellular or molecular cause satisfactorily explains the condition in all patients, Dr. Caprioli writes. ...
Measuring the Quantity of Information Passed on From the Eye to the Brain
... recorded spikes of electrical impulses from ganglion
cells using a miniature multi-electrode array. ... processes neural signals when it detects light. ganglion
cells carry information from the retina to the ... of the visual world. The axons of the retinal ganglion
cells, with the support of other types of cells, ...
New Drug Effective for Low Blood Pressure
... down. When standing up, however, nerve signaling traffic in the autonomic ganglion
increases. Researchers theorized a drug that affects the autonomic ganglion
would improve nerve transmission for orthostatic hypotension patients and ...
Nanomedicine Gives the Way for Nerve Cell Regeneration
... inhibitory interface and the tissue beyond a CNS related injury. Using optic nerve and spinal cord tissues as in vivo models and dissociated retinal ganglion
neurons as an in vitro model, De Silva and his colleagues are currently investigating how these magnetic nanoparticles can be incorporated into ...
Software System to Improve the Function of Retinal Implants
... For this purpose, clinicians open the eye ball and attach a thin foil at the retina. Small protruding contacts reach neurons, which form the ganglion
cell layer of the retina. These electrical stimulation contacts feed camera signals into the optic nerve. The camera may be attached to a frame of ...