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Estrogen in Medical News

QuatRx Announces Further Positive Phase 3 Results For Ophena(TM) (Ospemifene Tablets) in Postmenopausal Vaginal Atrophy

... approval for Ophena(TM) , a new SERM (selective estrogen receptor modulator) for the treatment of the ... pain (dyspareunia) and irritation. Declining estrogen levels during menopause can cause tissues of the ... program. Fispemifene is a new selective estrogen receptor antagonist that is in Phase 2 studies as ...

Study Evaluating Efficacy and Safety of Two Low-dose Regimens of PREMARIN Vaginal Cream for the Treatment of Moderate to Severe Vaginal Atrophy Now Published

... you should know about PREMARIN Vaginal Cream (an estrogen mixture)? Estrogens may increase the ... and Vaginal Atrophy Women produce less estrogen after menopause. When estrogen levels begin dropping, vaginal walls become ...

Migraines Linked to Reduced Breast Cancer Risk

... Researchers suspect estrogen levels play a part in the connection ... triggers for migraine are also things that reduce estrogen levels," he said. It's well-known that many ... that women who have migraines may have drops in estrogen levels that trigger migraines. And women who have ...

Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer

... the biological effects of a novel membrane estrogen receptor, a finding that has potential ... transmembrane receptor, GPR30/GPER-1, to specific estrogen binding, rapid estrogen signaling and breast cancer metastasis. "What is ...

New Data: Efficacy and Responder Analyses of Divigel(R) (estradiol gel) 0.1 percent for the Treatment of Menopause

... women the lowest effective FDA-approved dose of estrogen therapy for MSVMS in post-menopausal women and ... treatment of MSVMS associated with menopause. The estrogen in Divigel(R) is derived from plant sources and is identical to the primary estrogen produced by a woman's ovaries before menopause. ...

Defeating nicotine's double role in lung cancer

... asked if nicotine may be to lung cancer what estrogen is to breast cancer. Eliot R. Spindel, M.D., ... Oregon Health & Science University, stated that estrogen can stimulate the development of breast cancer ... of breast cancer appears to be decreasing as estrogen hormone replacement therapy is being used less ...

Estrogen linked to lowered immunity in fish

... Exposure to estrogen reduces production of immune-related proteins in ... revealed that largemouth bass injected with estrogen produced lowered levels of hepcidin, an important ... study demonstrating control of hepcidin by estrogen in any animal. Besides being an important ...

HRT Ups Death Risk for Women With Lung Cancer

... regimen of hormone therapy, not to the use of estrogen on its own. The findings do appear to be ... combined hormone therapy -- conjugated equine estrogen (CEE) plus medroxyprogesterone acetate (MPA) -- ... months in favor of the group that did not receive estrogen plus progestin," Chlebowski said. The ...

Fighting "Brain Fog": How the Right Hormones Can Improve Mental Sharpness for Women

... example, most women aged 40 to 50 are actually estrogen dominant and benefit greatly from taking ... hormone levels shift again, and bioidentical estrogen replacement is also needed." Randolph, ... cream. Even after the body's level of estrogen has dropped so that periods stop ...

KLRI Releases 3rd Annual Report On Year's Top Longevity Research Findings

... Hormones and aging. While the Kronos Early estrogen Prevention Study (KEEPS), designed to evaluate the effect of estrogen on heart disease in younger, postmenopausal women ... and age-related skin changes and the effects of estrogen on blood cell function and the formation of blood ...

Estrogen May Help Men's Hearts

... TUESDAY, May 12 (HealthDay News) -- estrogen has long been implicated as being heart ... suggests that having just the right amount of estrogen might be helpful for men as well. The study, ... with heart failure who had the lowest levels of estrogen had about four times the risk of dying as men ...

Equality of the sexes? Not always when it comes to biology

... system than men. In fact, the production of estrogen by females could have a beneficial effect on the ... Academy of Sciences . More specifically, estrogen naturally produced in women seems to block the ... blocks the inflammatory process. The presence of estrogen would therefore have a beneficial effect on ...

Penn State professor investigates estrogen, heart disease connection in women

... will shed light on the connection between estrogen deficiency, heart disease and aging in women. ... women lose their ability to produce the hormone estrogen and researchers believe that low estrogen levels somehow make women more vulnerable to ...

Lilly Granted Preliminary Injunction to Prevent Launch of Generic Raloxifene

... Ltd. About EVISTA EVISTA(R), a selective estrogen receptor modulator (SERM), recently classified by the FDA as an estrogen agonist/antagonist, is indicated for the ... before taking EVISTA. Do not take EVISTA with estrogen in the form of pills, patches, or injections. ...

Korein Tillery Takes Herbicide Atrazine Case to the Court of Public Opinion

... causing demasculinization in male frogs and is an estrogen disruptor. Dr. Hayes explains, "In frogs and ... be having the same effect over the production of estrogen in people." High levels of estrogen he notes, have been linked to breast cancer. ...

Genomic Health Announces Study Confirming Prognostic Value of Oncotype DX(R) Recurrence Score(R) Result in Japanese Breast Cancer Patients

... prognostic value in Japanese women with estrogen receptor-positive early-stage breast cancer. ... a large portion of patients in Japan who had estrogen receptor-positive early-stage breast cancer as ... tumor samples from 200 patients with early-stage, estrogen receptor-positive, lymph node negative breast ...

Oral contraceptives associated with increased risk of lupus

... combined oral contraceptives (COCs) containing estrogen and progestogen. During an average of eight years ... women and possibly a dose-response effect of estrogen on SLE onset," according to the authors. They note that estrogen can directly modulate the immune response, which ...

Grapefruit-Heavy Diet Helped Spur Dangerous Clot

... grapefruit juice magnifies the effects of the estrogen in the birth control pill the woman was taking; one effect of estrogen is to increase the likelihood of clotting. The ... it was the combination of grapefruit juice, the estrogen in the birth control pill, the clot-inducing ...

Penn study examines power of exercise to prevent breast cancer

... the disease. Building on evidence that reducing estrogen in the body reduces cancer risk, and that elite female athletes experience a drop in estrogen levels that often cause them to stop ovulating ... undergo genetic testing. Previous research on estrogen exposure strongly suggests that reducing ...

New study suggests Rx estrogen delivery through the skin may show safety benefits as opposed to oral delivery

... NY (March 25, 2009) Transdermal delivery of estrogen therapy available by prescription "seems not to ... Menopause Society. Prescription transdermal estrogen therapy is bioidentical to estrogen produced by a woman's ovaries before menopause ...

NYU study finds new risk factor for melanoma in younger women

... genetic variant in a gene called MDM2. When estrogen binds to this gene, it turns on production of ... the Institute for Advanced Study, Princeton, the estrogen binds more strongly, resulting in far greater ... of the MDM2 protein. Women with higher estrogen levels and who also have the genetic variation ...

Bionovo to Present at Wall Street Analyst Forum's 20th Annual Institutional Investor Conference

... to the Endocrine Society indicating that estrogen receptor beta may have a role in cancer ... describing the structural elucidation of active estrogen receptor beta selective compounds from VG101, ... well provide superior efficacy and safety versus estrogen therapy. About Bionovo, Inc. ...

Preventium is 'where the prevention of breast and prostate cancer begins'

... The researchers have discovered that certain estrogen derivates (metabolites) can react with ... initiate the start of breast and prostate cancer. estrogen can initiate cancer when natural protective ... function properly in the body, which then allows estrogen metabolites to react with DNA. Since both men and ...

March 2009 Mayo Clinic Women's HealthSource Highlights Molecular Breast Imaging, Canes and Walkers, Training for an Event and Hormone Therapy for Women

... Initiative (WHI) found that older women taking estrogen plus a synthetic form of progesterone (progestin) ... example, direct application of a very low dose of estrogen cream can relieve vaginal dryness while ... side effects. Age might matter: Although estrogen therapy is no longer recommended to prevent ...

Lilly Granted Temporary Restraining Order to Halt Launch of Generic Raloxifene

... Ltd. About EVISTA EVISTA(R), a selective estrogen receptor modulator (SERM), recently classified by the FDA as an estrogen agonist/antagonist, is indicated for the ... before taking EVISTA. Do not take EVISTA with estrogen in the form of pills, patches, or injections. ...

Technique May Let More Women Use Tamoxifen

... -- Researchers have found a way to "switch on" estrogen sensitivity in breast tumor cells, thereby making ... aromatase inhibitors, which also interfere with estrogen production in the body. "We are currently ... alternatives for the group of women who start out estrogen receptor-positive but later become negative and ...

Early Menopause Doubles Stroke Risk

... Experts suspect lowered estrogen levels might be a factor FRIDAY, ... menopause at age 55 or older. None had used estrogen before menopause. The researchers followed the ... the link remains unclear, she said. The lower estrogen levels associated with menopause might play a ...

Estrogen found to increase growth of the most common childhood brain tumor

... Cincinnati (UC) researchers have discovered that estrogen receptors are present in medulloblastomathe most ... act to increase tumor growth and progression. estrogen receptors are also the most important drug ... that we may be able to use anti-hormone or estrogen drug therapieslike those used to treat breast ...

Newly Published Menopause Study: 'Bioidentical' and FDA-Approved Divigel(R) (estradiol gel) 0.1 Percent Safe and Effective Treatment for Moderate to Severe Hot Flashes Associated With Menopause

... and offers women the lowest FDA-approved dose of estrogen therapy for hot flashes," Dr. Richard ... vasomotor symptoms associated with menopause. The estrogen in Divigel(R) is derived from plant sources and is identical to the primary estrogen produced by a woman's ovaries before menopause. ...

Jan Ake Gustafsson, M.D., Ph.D., Joins Bionovo's Scientific Advisory Board

... Dr. Gustafsson's landmark discovery of the estrogen receptor beta (ERB) transformed the future of ... to the more recent discovery of a second estrogen receptor, estrogen receptor beta, resulting in a paradigm shift in ...

Internationally Acclaimed Researcher Joins UH Faculty

... bring an internationally recognized team to study estrogen action in normal and diseased tissues that will ... and expressed. Gustafsson discovered a major estrogen receptor protein and has worked in a variety of ... discovered the existence of a previously unknown estrogen receptor that plays a pivotal role in the ...

Drop in Breast Cancer Rates Due to Drop in HRT Use

... "safe" period for combined use of progestin and estrogen to relieve postmenopausal symptoms was probably ... women assigned to take the combined HRT (but not estrogen alone). When Chlebowski's group looked in more ... use? "Our paper suggests after starting estrogen plus progestin, you probably have two or three ...

Study identifies potential 'safe period' for hormone replacement use

... risk of breast cancer, confirming that the use of estrogen plus progesterone increases the risk of both ... a two-year "safe" period for the use of estrogen and progesterone; and finding that the increased ... and that use of a regimen that includes both estrogen and progesterone is more detrimental for the ...

HRT Shrinks the Brain

... women taking conjugated equine estrogens (either estrogen alone or estrogen plus progestin). In the primary paper, ... of age who took CEE-based hormone therapy [either estrogen alone ...

Hormone Therapy May Cut Colorectal Cancer Risk

... colorectal cancer among women who had ever used estrogen alone, a 25 percent reduced risk among women ... and a 26 percent reduced risk among those using estrogen for 10 or more years. Among women taking estrogen plus progestin, there was a 22 percent reduced ...

Also in the Dec. 30 JNCI

... This relationship has been attributed to the high estrogen levels in many obese postmenopausal women. ... of insulin in breast cancer while controlling for estrogen levels. In the current study, Marc Gunter, ... other breast cancer risk factors, including estrogen levels. "These data suggest that ...

Diet may cut second breast cancers in women without hot flashes

... hot flashes are associated with lower circulating estrogen levels, while the absence of hot flashes is associated with higher estrogen levels. Reducing the effect of estrogen is a major treatment strategy in breast cancer," ...

Diet may cut risk of breast cancer recurrence in women without hot flashes

... hot flashes are associated with lower circulating estrogen levels, while the absence of hot flashes is associated with higher estrogen levels. Reducing the effect of estrogen is a major treatment strategy in breast cancer," ...

HRT Users Who Get Breast Cancer Less Likely to Die

... diagnosis were more likely to be diagnosed with estrogen receptor-positive cancer, as well as having ... positive breast cancers depend on estrogen to grow. Giving anti-estrogen therapy (such as ... [current or previous hormone use], those on estrogen alone, and those on estrogen-progestin." Those ...

Osteoporosis Drug Seems to Shrink Breast Tumors

... reducing the risk of recurrences in women with estrogen receptor-positive tumors. Encouraging findings ... alone. After compensating for variables such as estrogen receptor status and treatment duration, residual ... included: Postmenopausal women with estrogen receptor- and/or progesterone receptor-positive ...
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