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Encephalopathy in Medical News

Hyperion Therapeutics Announces Results of Phase I Study in Patients With Liver Cirrhosis

... preparing to initiate phase II trial in hepatic encephalopathy - SOUTH SAN FRANCISCO, Calif., June 2 ... and coagulation variables. "Hepatic encephalopathy (HE) is a significant clinical problem," said ... for the use of HPN-100 in treating hepatic encephalopathy later this year. About ...

Resuscitated Newborns at Risk for Lower IQs

... birth called encephalopathy. The signs of encephalopathy can be seizures, abnormalities of muscle tone, ... require resuscitation at birth but are free of encephalopathy will have normal growth and development. "It ... who had to be resuscitated and had symptoms of encephalopathy had more than a sixfold risk of having a low IQ. ...

JCI table of contents: Dec. 20, 2007

... of a fatal brain disease Hypertensive encephalopathy is an often-fatal disease of the brain that ... of delta-PKC protects against hypertensive encephalopathy through prevention of blood-brain barrier ... ACCOMPANYING COMMENTARY TITLE: Hypertensive encephalopathy and the blood-brain barrier: is delta-PKC a ...

Hyperion Therapeutics Raises $60 Million Series C

... resulting in brain damage, coma, and/or death. About Hepatic encephalopathy Hepatic encephalopathy (HE) is a serious but potentially reversible neurological disorder that ...

Farmed fish may pose risk for mad cow disease

... be contracted by eating parts of an animal infected with bovine spongiform encephalopathy (BSE or mad cow disease). An outbreak in England attributed to infected ... the United Kingdom attributed to eating infected beef. Bovine spongiform encephalopathy has been identified in nine Canadian and three U.S. cattle. ...

Center for the Study of Traumatic Encephalopathy announces new findings

... FLA) Leading medical experts at the Center for the Study of Traumatic encephalopathy (CSTE) at Boston University School of Medicine (BUSM) reported today that ... former Tampa Bay Buccaneer Tom McHale was suffering from chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by head trauma, when he died in ...

Hyperion Therapeutics Announces Enrollment of First Patient in Phase 2 Clinical Trial in Patients With Hepatic Encephalopathy

... multi-factorial disease process." About Hepatic Encephalopathy Hepatic encephalopathy (HE) is a serious, progressive and potentially reversible neuropsychiatric ... therapy for the treatment of acute hyperammonemia and associated encephalopathy in patients with deficiencies in enzymes of the urea cycle. In acute ...

Liver Cirrhosis May Also Harm Brain, Heart

... and a condition known as hepatic (liver) encephalopathy, which occurs when an increasing amount of unfiltered toxins reaches the brain. Hepatic encephalopathy can affect both physical and mental performance. All three conditions are linked to increased systemic inflammation, say a team from the ...

Give the foie gras a miss

... mechanism akin to the replication of similar protein fragments in the brain diseases Creutzfeldt-Jakob Disease (CJD), scrapie, and Bovine Spongiform encephalopathy (BSE), also known as mad cow disease, might occur when amyloid fibrils enter brain tissue or the pancreas. He points out that high levels of these ...

Hunter-Killed Elk Test Negative for CWD and Other Diseases

... for and collect samples from deer and elk that appear sick or behave abnormally. First identified in 1967, CWD is a transmissible spongiform encephalopathy (TSE) that affects cervids, including all species of deer, elk and moose. It is a progressive and always fatal disease, which scientists theorize is ...

Bioniche Invited to Participate in Canadian Beef Value Chain Roundtable

... Beef Value Chain Roundtable was launched in January, 2003 and emerged as a key vehicle for helping ensure a coordinated response to Bovine Spongiform encephalopathy (BSE) and as a key focal point for various working groups to engage with representatives of the entire beef value chain. Now more focused on ...

Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients

... injection site necrosis, vasculitis and phototoxicity. Additional serious adverse events included hallucinations, bipolar disorder, mania, encephalopathy (usually elderly treated with higher doses of PEGINTRON), hypotension, tachycardia, retinopathy including macular edema, retinal hemorrhage, cotton ...

Schering-Plough Announces FDA Approval of PEGINTRON(TM) and REBETOL(R) Combination Therapy for Treating Pediatric Hepatitis C

... injection site necrosis, vasculitis and phototoxicity. Additional serious adverse events included hallucinations. bipolar disorder, mania, encephalopathy (usually elderly treated with higher doses of PEGINTRON), hypotension, tachycardia, retinopathy including macular edema, retinal hemorrhage, cotton ...

Mutant proteins result in infectious prion disease in mice

... to chronic wasting disease (CWD). CWD is a highly infectious prion disease found in free-ranging deer and elk that is similar to bovine spongiform encephalopathy (BSE, or "mad cow disease") in cattle and Creutzfeldt-Jakob disease in humans. Prion diseases are thought to be a result of a misfolded form of the ...

Possible association between CP and LC of alcoholic etiology

... and elastase-1 test was altered in only 7% and severely altered in none. In patients with CP, clinical characteristics of cirrhosis such as ascites, encephalopathy and gastrointestinal haemorrhage were present in one case, Child-Pugh grade > A in 5.7%, and altered indocyanine green test in 1.9% cases. In ...

New Test Scans Beef for Mad Cow Disease

... slaughter has been developed by U.S. researchers. They said the test is an advance in efforts to protect the human food chain from bovine spongiform encephalopathy (BSE) or "mad cow disease." The removal of brain, spinal and other central nervous system tissue after slaughter is "one of the highest priority ...

Federal Advisory Committee Votes to Include Newly Licensed Pentacel(R) Vaccine in Vaccines for Children Program

... of a prior vaccine containing tetanus toxoid; or if adverse events have occurred in temporal relation to receipt of pertussis-containing vaccine. encephalopathy within 7 days of administration of a previous dose of a pertussis-containing vaccine or a progressive neurologic disorder is a contraindication. ...

FDA Approves KINRIX(TM) - New Combination Vaccine for Children

... fever, and loss of appetite. Previous hypersensitivity to any component of KINRIX, including neomycin and polymyxin B, is a contraindication. encephalopathy within 7 days of administration of a previous pertussis-containing vaccine or a progressive neurologic disorder is a contraindication. The decision ...

US FDA licenses Sanofi Pasteur's new pediatric combination vaccine, pentacel

... of a prior vaccine containing tetanus toxoid; or if adverse events have occurred in temporal relation to receipt of pertussis-containing vaccine. encephalopathy within 7 days of administration of a previous dose of a pertussis-containing vaccine or a progressive neurologic disorder is a contraindication. ...

U.S. FDA Licenses Sanofi Pasteur's New Pediatric Combination Vaccine, Pentacel(R)

... of a prior vaccine containing tetanus toxoid; or if adverse events have occurred in temporal relation to receipt of pertussis-containing vaccine. encephalopathy within 7 days of administration of a previous dose of a pertussis-containing vaccine or a progressive neurologic disorder is a contraindication. ...

First atomic-level look at a protein that causes brain disease

... how certain kinds of proteins, called prions, cause degenerative brain diseases such as CAA. More common prion diseases include bovine spongiform encephalopathy (mad cow disease), and Creutzfeldt-Jakob disease in humans. All are incurable and fatal. Jaroniec understands that any discovery related to prions ...

Chronic Exposure to Solvents Disturbs Brain's Wiring

... may cause disturbances in the brain's wiring, researchers report. These abnormalities play a role in a condition called chronic solvent-induced encephalopathy (CSE), the Dutch team conclude in the April issue of the Annals of Neurology . People with CSE experience problems with memory, attention and ...

Disturbances in brain circuitry linked to chronic exposure to solvents

... memory, attention and psychomotor function, frequently persists even after exposure has ceased, is usually referred to as chronic solvent-induced encephalopathy (CSE). Although CSE is an acknowledged occupational disease in an increasing number of western countries, and is classified according to the World ...

Government Concludes Vaccines Caused Autism

... documents state that the vaccines administered to the claimant significantly aggravated an underlying condition that ultimately led to regressive encephalopathy and symptoms of autism. According to official court documents, the child was developing normally until given the vaccines, and shortly after the ...

Better access to cool caps improves outcomes, lowers cost of treating asphyxia in newborns

... a regional healthcare system could lead to a 23 percent reduction in the number of newborns likely to develop permanent damage from hypoxic-ischemic encephalopathy (HIE), a form of asphyxia that damages the central nervous system. In Massachusetts, this would produce estimated annual savings of $4.4 million. ...

PEGINTRON(TM) and REBETOL(R) Approved in European Union for Retreating Hepatitis C Patients Who Failed Previous Pegylated or Non-Pegylated Interferon Therapy

... with PEGINTRON and/or INTRON A be discontinued, and the patient be carefully followed with psychiatric intervention, as appropriate. Cases of encephalopathy have been observed in some patients, usually elderly, treated with higher doses of PEGINTRON and/or INTRON A. Ischemic and hemorrhagic ...

Hepatitis C treatment reduces the virus but serious liver problems may progress

... at risk for progressive liver disease. The outcomes assessed in HALT-C were death, liver cancer, ascites (excess fluid in the abdomen), or encephalopathy (brain and nervous system damage), and for those who did not have cirrhosis initially, the development of cirrhosis. At the end of the study, 34.1 ...

Primary biliary cirrhosis more severe in African-American and Hispanic patients

... authors report. Minority patients reported more limitation of activity, more severe itching and more serious complications such as ascites, hepatic encephalopathy and variceal bleeding. Results from the laboratory tests confirmed the disparity in disease severity. Mostly as a result of their poorer health ...

Gene Mutations Causing Rett Syndrome Occur in Both Sexes

... in young infant males who develop progressive encephalopathy including respiratory insufficiency, ... in Baltimore. "Infant males with progressive encephalopathy may go undiagnosed because the prevailing ... the role of the gene and its contribution to the encephalopathy of Rett syndrome," said Dr. Gary Goldstein, ...

Whole-body hypothermia reduces risk of death in Encephalopathy in infants

... Among infants, hypoxic–ischemic encephalopathy due to acute perinatal asphyxia remains an ... in childhood//. Infants with moderate encephalopathy have a 10% risk of death, and those who survive ... risk of disabilities. 60% of infants with severe encephalopathy die, and many, if not all, survivors are ...

Brain-child of Natus Medical, “Cool Cap”, Protects Brains of Babies Born With HE

... Babies are cool indeed, but those born with hypoxic-ischemic encephalopathy may need to get cooler at the top, to protect their brain. Some babies do ... who come into the world, with reasonable to intense hypoxic-ischemic encephalopathy (HIE). This product could be an answer to such problems during ...

Pump up the Thiamine levels after gastric surgery

... these comments to make, “This case highlights the variability of Wernicke encephalopathy where the classic trio of eye movement abnormalities, confusion, and ... gastric bypass surgery are diverse. Vitamin B1 deficiency and Wernicke encephalopathy should be carefully considered in surgically treated obese patients." ...

Mad Cow Disease Has Roots Traceable To Man

... has got traces of human remains, may be at the root of bovine spongiform encephalopathy or the mad cow disease. A report in the latest issue of The Lancet had ... Sheep scrapie or a previously undetected bovine transmissible spongiform encephalopathy (TSE) that arose spontaneously has long been considered as candidates. ...

New Insights into Prion Propogation

... -- infectious, oddly-folded proteins that are the main suspects in fatal neurodegenerative diseases such as Cruetzfeldt-Jakob and bovine spongiform encephalopathy , or "mad cow" -- remain mostly a mystery to scientists. Very few prions have been fully described. How they infect and propagate is not fully ...

Caution Against Re-use of Dental Tools

... there have been no such cases yet. This new advice to Dentists is only precautionary based on the recommendation from the expert Spongiform encephalopathy Advisory Committee. This would be applicable to instruments called as files and reamers. These instruments are employed most frequently to remove ...

Rare Brain Condition Linked to Obesity Surgery

... their conclusions by extensive survey of data relating to patients who had completed various types of bariatric surgery. The syndrome - Wernicke encephalopathy - affects the nervous system and brain, and can lead to confusion and the inability to co-ordinate movement. It is said to be caused by a lack of ...

Chronic Wasting Disease In Alberta

... disease// that has affected the deer population. This disease which affects the nervous system of the deer is similar to bovine spongiform encephalopathy or the mad cow disease that affects the cattle. Lyle Fullerton, speaking on behalf of Alberta Sustainable Resource Development said that as the ...

New Mad-Cow Case Detected in Canada Bull

... animal feed systems. However, the agency did not reveal where the animal was found or how old it was. When Mad Cow disease, or Bovine Spongiform encephalopathy (BSE) gets transmitted to people, who eat infected animals, they are at risk of contracting a rare form of deadly brain disease known as ...

Scientists Reverse Mad Cow Disease in Mice

... brain was also reverted and normal memory restored. The fact that these mice were very young in age contributed to the revival. Bovine Spongiform encephalopathy (BSE) which is commonly called as the cattle disease or mad cow disease is a neurodegenerative disorder has its equivalent in humans called the ...
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