Researchers identify individuals at risk for developing colon cancer
... activities. The individuals with this genetic defect
appeared to develop colon cancer later in life. ... at UH Case Medical Center and Johns Hopkins.
in glycosylation is a hallmark of many cancers, but the reason for this defect
has been unknown. This study discovered the ...
For the First Time in U.S. History, Congress Addresses the Needs of the Congenital Heart Defect Population by Introducing the 'Congenital Heart Futures Act'
... defects (CHDs) - America's most common birth defect
that affects approximately one out of 120 babies ...
"A child is born with a congenital heart defect
every fifteen minutes," says Senator Richard ... increase of public funding of congenital heart defect
efforts," says Bill Foley, Executive Director of ...
Obese Moms More Likely to Have Babies With Birth Defects
... defects, cleft lip and palate, and anencephaly (a defect
in brain development). Birth defects are a ... pooled risk of having a baby with a neural tube defect
was 87 percent higher for obese mothers compared ... risk of an obese woman having a baby with a birth defect
is still low. "Birth defects occur in between 2 ...
The Children's Heart Foundation to Support National Congenital Heart Coalition (NCHC) on Capitol Hill by Participating in National Congenital Heart Lobby Day on February 10
... Heart Disease Registry, Congenital Heart defect
Research and Education
CHICAGO, Feb. 9 ... for CHDs, the most prevalent and deadly birth defect
National Congenital Heart Lobby Day falls during Congenital Heart defect
Awareness Week (February 7-14, 2009), an annual ...
Neural Stem Cells May Help Repair Spina Bifida in Utero
... results in the treatment of a this congenital defect
(Vocus) ... spinal cord, along with surgical coverage of the defect
while in utero, may help repair spina bifida ... develop outside, instead of inside, the body. The defect
develops at around the fourth week of gestation ...
Sexually transmitted disease, urinary tract infections may be bad combination for birth defect
... to have babies with gastroschisisa severe birth defect
in which infants are born with their intestines ... School of Medicine and director of the Utah Birth defect
Network. The National Center on Birth Defects and ... Control and Prevention (CDC), and the Utah Birth defect
Network were partners in the study.
Cystic Fibrosis Foundation announces positive early results for phase 2 clinical trial of VX-770
... an oral drug in development that targets a basic defect
in CF, showed promising results in an ongoing ... small molecules can correct the basic defect
and affect the clinical indicators of cystic ... screeningto find compounds to attack the core defect
in CF. Since that time, the Foundation has ...
New cataract gene discovered
... researchers was able to identify the location and defect
in the coding region of the gene through analysis ... cell mem-branes. Surprisingly, this genetic defect
may also lead to the condition of renal glucosuria, a non-pathological kidney defect
with elevated levels of glucose in the urine, but ...
Children's Heart Foundation (CHF) Hosts 4th Annual Arizona 'Swing For Their Hearts' Golf Event
... Raise Awareness and Funding for Congenital Heart defect
TUCSON, Ariz., Feb. 14 /PRNewswire/ ... Kline -- born with a congenital heart defect
-- hosts the 4th Annual Arizona "Swing for Their ... much-needed funding for congenital heart defect
research, the number one ...
Oregon researchers discover a mechanism leading to cleft palate
... mechanism for cleft palate, a common birth defect
in humans that has challenged medical ...
The first known attempt to correct the defect
occurred in 500 A.D. The defect
occurs with or without cleft lip (a separation of ...
Heart attack risk from smoking due to genetics
... less to do with tobacco than genetics. A common defect
in a gene controlling cholesterol metabolism ... The findings also show that smokers without the defect
normally have heart attacks no sooner than their ... They found that smokers with the genetic defect
had their first heart attack eight to nine years ...
Brain Defect Helps Drive Fragile X Syndrome
... 20 (HealthDay News) -- A newly discovered brain defect
might be a target for the treatment of the ...
"We discovered what the specific underlying defect
is," he said. "It is actually a defect
in the mGluR5 receptor, which is on the surface ...
Study Puts 1 Alzheimer's Theory in Doubt
... one leading hypothesis is that there is a defect
in the mitochondrial energy production system in ... he said.
The findings suggest that a defect
in the COX10 gene develops after amyloid ... been thought, Moraes said.
"The mitochondrial defect
in Alzheimer's disease appears to be a ...
Heart Defect Spotted During Surgery May Not Need Repair
... 14 (HealthDay News) -- Patients may not benefit from repair of a heart defect
that's discovered during surgery for another condition, a new study has found.
-- patent foramen ovale (PFO) -- is an opening in the upper chambers of ...
Young People With Heart Defects Not Checking In With Heart Doc
Another study defines genetic risk of having same heart defect
as parent, sibling
The risk of having a heart defect
is three-fold to 80-fold higher in families who have already experienced ...
First-degree relatives of patients with bicuspid aortic valve should be screened
... anomaly, affecting up to two percent of the general population. The defect
can result in calcification deposits on the heart valve, leakage of the ... the gene has not been identified, and in some families, incidence of this defect
could run as high as 20 percent.
A new study, published in the ...
Hypospadias, a birth defect of the male urethra, is not increasing in New York state
... by increases in testicular cancer and hypospadias -- a congenital defect
in which the opening of the urethra is on the underside, rather than at ... Children of mothers aged 35 years and older show higher rates of the birth defect
-- a finding that is consistent with other recent epidemiological studies. ...
Packard/Stanford study suggests two causes for bowel disease in infants
... They reviewed medical records from 76 infants who had a congenital heart defect
together with necrotizing enterocolitis and 126 infants who had ... that babies who had both necrotizing enterocolitis and a congenital heart defect
fared better than those who had necrotizing enterocolitis alone. Even ...
Study Links Pesticides to Birth Defects
... that if our suspicions are right, and pesticides are contributing to birth defect
risk, we can reverse or modify the factors that are causing these lifelong ... even mothers who didn't have these risk factors had higher overall birth defect
rates for babies conceived from April to July, the study found.
2-day results predict ultimate response to therapy in chronic hepatitis C
... important because they point toward the presence of some block or defect
in the immediate antiviral response of those who do not respond to ... are necessary to uncover the relevant mechanisms that underlie this defect
in IFN signaling with the hope that such mechanisms can be manipulated to ...
B12 Deficit May Boost Risk of Birth Defects
... Either the women had previously given birth to a baby with a neural tube defect
or were known to be carrying babies with the disorder.
Women with B12 ... had roughly three times the risk of having a child with a neural tube defect
as those with higher B12 blood levels. Those women whose levels were less ...
Long-term outlook good for rotator cuff repairs
"Our obvious concern for patients who have a recurrent rotator cuff defect
after surgical repair is that symptoms may recur over time. Our study ... benefit from surgery and remain asymptomatic, even if a recurrent defect
is present. This is encouraging for both the surgeon and the patient ...
Scientists identify new congenital neutropenia syndrome and causative gene mutation
... investigator of the study. "Knowledge about the underlying genetic defect
is an important first step in developing a targeted therapy."
The ... mutation in a subgroup of SCN patients: homozygous mutations (where the defect
is present in both copies of the gene) in the HAX1 gene.
To conduct the ...
Study investigates Gore-tex-type device to stop strokes and mini-strokes
... FDA for the treatment of atrial septal defects (ASDs), a congenital heart defect
found in young children.
"This PFO-closure device uses a ... adulthood. It is not until a patient experiences a stroke that a PFO defect
is often diagnosed. Many of these strokes occur in people under the age ...
Pediatric Heart Surgeons May Be Best Choice for Adults
... a congenital heart defect, a new study suggests.
A congenital heart defect
occurs when there's abnormal pre-birth development of the heart or blood ... analyzed a national database to identify 30,250 congenital heart defect
surgeries performed from 1988 to 2003. They compared results of cases ...
NIH scientists discover crucial control in long-lasting immunity
... Their finding may also explain why some individuals who have a genetic defect
that prevents them from making this proteincalled SAPsuffer from lethal ... is rarely fatal (Epstein-Barr virus), while others with this genetic defect
have problems with B-cell lymphomas.
The new study was a ...
Oral vitamin D may help prevent some skin infections
... at UC San Diego found that use of oral vitamin D appeared to correct a defect
in the immune systems in patients with this skin disease. Their findings ... that oral vitamin D use by the patients appeared to correct the skin's defect
"These results suggest that supplementation with oral ...
US Drug Watchdog Expands Its National Investigation Into The Drug Called Digitek, And Would Like To Talk To Possible Victims
... According to the Food & Drug Administration (FDA), "the Digitek defect
could expose users to twice the amount of active ingredient, which could ... is sold generically as digoxin by several companies.
The Digitek defect
could expose users to twice the amount of active ingredient, which could ...
Bat Scan to the Rescue: New Clubhouse CT Scanner Helps Eliminate Exploding Bats
... than ash and supposedly more durable, but there is a
greater chance of defect
in a maple bat compared with a bat made of ash.
Hidden defects in the ... rules on the measurement of bat handles -- no reports
about a maple bat defect
identifier have been issued.
BatteryMate(TM) is ...
St. Jude study shows how T cell's machinery dials down autoimmunity
One implication of our findings is that a relatively small defect
in the efficiency of signal transduction through the T cell receptor could ... need a very big reduction in T cell receptor signal strength to have a defect
in negative selection.
The study also showed that different T cell ...
The Children's Heart Foundation Teams Up With ProFlowers(R) to Raise Awareness and Funding for the Leading Birth Defect in America
... is the country's leading organization
solely committed to congenital heart defect
(CHD) research funding and is
comprised of parents, family members and ... is the only organization created solely to fund
congenital heart defect
research. There are currently six chapters
nationwide with aggressive ...
Muscle Weakness Found in Some Autistic Children
... Genetic defect
in mitochondria might explain other aspects of the disorder, researcher ... muscle weakness in a child with autism may point to an underlying genetic defect
that's causing mitochondrial disease, which means the muscles don't get ...
American Academy of Dermatology Research Confirms Genetic Skin Barrier Defect Linked to Eczema
longstanding theory that atopic dermatitis might be caused by a defect
the skin's protective outer layer -- known as the epidermal barrier ... development
and functioning of the skin's impermeable outer layer cause a defect
allows irritants to penetrate the skin.
This new information ...
JCI table of contents: Nov. 21, 2007
... eventually develop leukemia, it is thought that a second genetic defect
occurring as the mice age is required for this to happen. Support for this ... have now determined that individuals with WBS also have a developmental defect
in the retina (the thin layer of neural cells that lines the back of the ...
Gene Mutation Key to Infertility in Male Mice
... If same defect
exists in men, it could lead to new treatments, study says,,,,
WEDNESDAY, Oct. 17 (HealthDay News) -- A defect
in a gene that's essential for the formation of functioning sperm cells ...
Impact of elevated homocysteine levels on vision under study
... tube defects, such as spina bifida, in their babies. People with a genetic defect
that results in a homocysteine level 40 times the norm are tall, thin, ... disease and retinopathy; and a second model of the rare genetic defect
that results in extraordinarily high homocysteine levels.
They will ...
Severe heart defect likely caused by genetic factors
... while the risk of a sibling having an HLHS-associated cardiovascular defect
was 22 percent. In families where a child and one parent had HLHS, the ... genes function, scientists hypothesize that HLHS may result from a primary defect
in the growth of muscle tissue during the hearts development.
AGA Medical Corporation Receives Approval for the AMPLATZER Muscular Ventricular Septal Defect Occluder
... in patients for
transcatheter closure of a complex ventricular septal defect
sufficient size to warrant closure (large volume left to right ... at high risk for surgical
closure based either on the anatomy of the defect
or the patient's overall
medical condition. VSDs typically occur in ...
Flu Shot May Be Less Effective in Those With Lupus
... the researchers added.
Flu vaccination did not impact lupus disease activity, the team said.
"Clinicians should be aware that this combined defect
might increase the morbidity and mortality due to influenza virus infection, in particular in patients receiving prednisone and/or azathioprine," the ...
Immune responses to flu vaccine are diminished in lupus patients
... responses to flu vaccination in SLE patients are representative of what occurs in daily practice. "Clinicians should be aware that this combined defect
might increase the morbidity and mortality due to influenza virus infection, in particular in patients receiving prednisone and/or azathioprine," ...