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Calcification in Medical News

Study estimates radiation dose, cancer risk from coronary artery calcium screening

... of the JAMA/Archives journals. Coronary artery calcification is associated with coronary artery disease. ... a tool for routine screening for coronary artery calcification in asymptomatic individuals as part of a ... undergoing CT screening for coronary artery calcification from a range of available protocols in the ...

Mutant rats offer clues to medical mystery

... mutation also leaves them susceptible to arterial calcification and, potentially, osteoporosis. The discovery ... found what could be the link that solves the calcification paradox, the puzzling association between metabolic bone disease and vascular calcification that has eluded researchers for years. Kohn, an ...

Heavy Traffic Can Be Heartbreaking

... from major traffic, the risk of coronary artery calcification was 63 percent higher for people living within 50 ... away amounts to a similar difference in coronary calcification as six months of aging," she said. Her team ... have suffered a greater increase in coronary calcification during the past five years. So what can ...

Apples and oranges: Tumor blood vessel cells are remarkably atypical

... researchers went on to demonstrate blood vessel calcification in human and mouse prostate tumor specimens. This bone-like calcification has also been described in diseased blood vessels ... in prostate cancer. "It is possible that calcification of tumor blood vessels could impair blood flow or ...

Readily available treatment could help prevent heart disease in kidney patients

... that high blood phosphate directly stimulates calcification of blood vessels and that phosphate-binding drugs ... the bloodstream. This therapy decreased arterial calcification in the mice. The treatment also diminished the ... phosphate in their bloodstreams and decreased the calcification of blood vessels. "BMP-7 restores the ability ...

Research sheds light on carotid artery stenting risk in elderly

... techniques to reduce risk. Increased aortic calcification in patients older than 75 years: Implications for ... factor that is a marker for aortic arch calcification and arch complexity. Preprocedural determination of aortic arch morphology and calcification may help to determine which elderly patients are ...

Cutting Phosphate May Protect Kidney Patients From Heart Trouble

... the researchers found that high blood phosphate levels directly stimulate calcification of blood vessels and that phosphate-binding drugs can decrease this ... called BMP-7 (bone morphogenic factor-7) reduced phosphate levels and calcification of blood vessels in mice with CKD. "Elderly osteoporosis patients and ...

Saline Wash May Ease Shoulder Tendonitis

... recovery time is about an hour. In 71.7 percent of patients, the calcification was fully removed in one treatment, resulting in improved mobility and ... presence of more than one calcification. In 3.8 percent of patients, the calcification had moved or dissolved before treatment. In 0.9 percent of patients, there ...

Marital Stress Linked to Heart Disease

... hardening of the arteries, Smith and his colleagues discovered. Levels of calcification were particularly high among those women whose husbands also were hostile. ... and received free CT scans of their coronary arteries to check for any calcification that could lead to future risk of heart attack. Couples were recruited ...

Researchers Discover the Tale Behind Short Dogs

... which the team believes may cause growth receptors to be switched on at the wrong time during fetal development. This may be behind the known calcification of growth plates that prevents these breeds' legs from growing, a condition known as disproportional dwarfism, or chondrodysplasia, that is ...

First-degree relatives of patients with bicuspid aortic valve should be screened

... instead of the normal three, is the most common cardiac anomaly, affecting up to two percent of the general population. The defect can result in calcification deposits on the heart valve, leakage of the valve and may results in a feeling of tightness in the chest as well as shortness of breath. The ...

Patients Call for Continued FDA Preemption Authority

... pain after receiving a neurostimulator. Tom Price, a long-distance runner from Syracuse, New York, was unable to run more than a mile due to calcification and severe regurgitation in his bicuspid aortic valve. After aortic valve replacement, he has resumed his active lifestyle. Mike Roman, from ...

Computer based model helps radiologists diagnose breast cancer

... to help the radiologist calculate breast cancer risk based on abnormality descriptors like mass shape; mass margins; mass density; mass size; calcification shape and distribution," said Elizabeth S. Burnside, MD, and Jagpreet Chhatwal, MD, lead authors to the study. "When the radiologist combined his/her ...

Bioabsorbable stents show promise

... by far the most straight forward cases. The study doesn't show us if the new stent will work in real world situations of patients with long lesions, calcification or bifurcations." ...

Proper Sleep May Help Clear Arteries

... of potential risk factors, such as sex, race, and smoking habits, the researchers found that one more hour of sleep a night decreased the risk of calcification by a third. That's about as much as a 16.5-point reduction in blood pressure, the researchers said. "Nothing came out of the study as appearing to ...

Deaths From Heart Disease, Stroke Down 30%

... improving," she said. Yet the new report also foreshadows future problems, she noted. For example, it is now possible to measure coronary artery calcification -- deposits that can thicken to block arteries. One U.S. study found that 15 percent of men ages 33 to 45 and 5.1 percent of women of the same age ...

Major New Resource for Bone and Mineral Disorders Released

... this edition includes: Abnormalities in Bone and Calcium Metabolism Following Burns Bone Cancer and Pain Vascular calcification Bisphosphonate-Associated Osteonecrosis of the Jaw New International Drug Formulary covering the most widely used drugs in major ...

Cytochroma Announces Positive Comparative Data on CTA018 in Chronic Kidney Disease Model

... Prolonged elevation of PTH causes excessive calcium to be released from bone into the blood, leading to softening of the bones (osteomalacia) and calcification of vascular tissues. SHPT affects 40-60% of patients with moderate CKD and approximately 90% of patients with severe CKD. About Mitsubishi Tanabe ...

Long-term HIV treatment may reduce risk for atherosclerosis

... and other lifestyle factors. The study, part of the Multicenter AIDS Cohort Study (MACS) initiated in 1983, measured levels of coronary artery calcification (CAC) in nearly 950 HIV-positive and HIV-negative men by CT scanning completed between 2004 and 2006. Controlling for traditional atherosclerosis ...

Bone Disease Test Shows Death Risk for Dialysis Patients

... bone disease and cardiovascular health in CKD patients. "Alkaline phosphatase has recently been shown to be associated with increased vascular calcification in experimental studies. Our study shows the clinical manifestation of this association in real-world patients," he said. More information ...

Fondness for Fish Keeps Japanese Hearts Healthy

... Japanese-American men. Along with giving blood samples, all of the men underwent electron beam computed tomography (EBCT) to measure coronary artery calcification (plaque deposits on the heart's arteries) and ultrasound examinations of the carotid artery in the neck. Overall, the researchers found that ...

July 2008 Mayo Clinic Women's HealthSource Highlights Vitamin D, Savvy Use of Sunscreen and Gastrointestinal Upset and Celiac Disease

... research indicates that lower vitamin D levels are associated with a number of factors that affect cardiovascular health, including coronary artery calcification and, possibly, congestive heart failure. So, how much vitamin D is enough? Recommendations from medical groups vary, but a daily intake in the ...

New study finds coronary arterial calcium scans help detect overall death risk in the elderly

... failure. This study indicates coronary arterial scans are effective in measuring overall death risk in the elderly." A calcium scan looks for calcification or a hardening of the arteries caused by high blood fats and calcium deposits in the arteries leading to and from the heart. These calcifications ...

Arterial Calcium Scans Can Predict Death Risk

... and how to clinically use bioimaging tests of early atherosclerosis remains a topic of debate. More information There's more on coronary calcification at the American Heart Association . SOURCES: Matthew Budoff, M.D., associate professor, medicine, Harbor-UCLA Medical ...

New method effective in detecting dangerous coronary plaque

... effects of lifestyle intervention (diet, exercise and omega-3 fatty acid supplement) or salsalate medication compared to placebo on coronary artery calcification as assessed by MDCTA. (See description below.) ...

Calcium Scans Help Predict Coronary Risk

... to the people who are screened has not been shown." A calcium scan using computed tomography (CT) costs $300 to $600. These scans look for calcification -- hardening of the arteries caused by high blood fats and calcium deposits that can eventually cause blood vessel blockage. The scan is a potential ...

Siemens Introduces New Dual Energy Applications to SOMATOM Definition

... distinction of the biochemical composition of renal calculi (e.g., uric acid or calcium oxalate) -- syngo DE Hardplaque for the display of calcification in the body and determination of the vessel status -- syngo DE Virtual Unenhanced for the subtraction of contrast medium in abdominal scans ...

Calcium Supplements Could Raise Heart Risks in Postmenopausal Women

... in light of calcium's beneficial effect on cholesterol. Yet the supplement has also been found to elevate blood calcium levels, which could speed up calcification of the blood vessels. Previous research has found that calcium build-up in the arteries can foreshadow coronary artery disease. "There is a point ...

FDA Approves the Opening of a Phase II Registration Protocol Using REXIN-G(R) for Osteosarcoma in California U.S.A.

... response evaluation process that is unique to the manner in which osteosarcoma responds favorably to therapy, i.e., with necrosis and increasing calcification in metastatic tumors and decreased glucose utilization using PET-CT imaging studies. Rexin-G is a tumor-targeted gene medicine that seeks out and ...

What's been causing your knee to ache? Smurfs!

... slowing the onset of arthritis and lessening its severity. Eventually, we hope to create an injection that will stop smurf2s ability to turn on the calcification and degeneration process in cartilage that leads to osteoarthritis. While Rosier admits the development of an injection is a long time off, he ...

Women Taking Oestrogen Therapy Showed Reduced Coronary Artery Calcification

... estrogens had significantly less coronary artery calcification at the end of the study period compared with those taking placebo. Coronary artery calcification is a marker of plaque in the arteries and a ... Wyeth is unaware of any coronary artery calcification data for women taking estrogen plus progestin. ...

More Fat Leads to Less Coronary Artery Calcification

... sign of heart disease called coronary artery calcification and body fat have found that, paradoxically, ... the skin had more evidence of coronary artery calcification than those with more fat. Thinner men also had more evidence of coronary artery calcification than men with a higher BMI. What it comes ...

Link Between Nanoparticles and Kidney Stones

... Medical scientists at Mayo Clinic are studying calcification at the molecular level in an effort to determine ... a growing body of scientific evidence that links calcification to the presence of nanosized particles, particles ... the unlikelihood that events linked to the calcification process are driven solely by physical chemistry, ...

Highway Robbers-Stealing Your Hearts Health

... extensive clinical examinations, and subjects had their coronary artery calcification (CAC) measured by electron-beam computed tomography (EBCT). The ... than 200 meters from major traffic. The chance of high coronary artery calcification was 63 percent greater for those living within 50 meters. For people ...

Women With Atypia Nearly Eight Times More Likely to Develop Breast Cancer

... group of women with the highest risk had three or more areas of atypia and calcification -- with a 10.4-fold risk over the general population. ... history of breast cancer. The majority (68.6 percent) of women showed calcification in the biopsy tissue, and 40 percent had multiple sites of atypical ...

Heart disease: Men Are From Mars, Women From Venus

... participants were subjected to CT examination to look for presence of calcification in the coronary arteries (arteries that supply the heart). Clogging of the ... calcification. Surprisingly, even asymptomatic patients were found to have calcification levels high enough to warrant a cardiac consultation. 'Women who are ...

Association Of Breast Arterial Calcifications With Diabetes And Hypertension

... retrospectively. Mammograms were evaluated for the presence of arterial calcification and results were coded. Patients who had been using insulin or oral ... of antidiabetic and antihypertensive therapy. Because breast pain and calcification decrease after renal transplantation in chronic renal diseases, the ...

Mutations in NOTCH1 cause an early developmental defect in the aortic valve

... left heart syndrome as well," said Dr. Srivastava. "Our work suggests that calcification of the aortic valve may be a manifestation of a mutation in NOTCH1 or ... of the study. Children’s with aortic valve defects develop early calcification of their aortic valves which leads to severe heart disease in their ...

Scan correlates susceptible heart plaque

... Researchers, felt that these 'hot spots' were distinct from areas of calcification - where the plaque is hardened. It may be that these 'hot spots' represent ... say the researchers, that these 'hot spots' were distinct from areas of calcification - where the plaque is hardened. It may be that these 'hot spots' represent ...
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