Keryx Biopharmaceuticals Announces Agreement with FDA on a Special Protocol Assessment for Phase 3 Trial of KRX-0401 (Perifosine) in the Treatment of Multiple Myeloma

... bortezomib (VELCADE((R))) and an immunomodulatory agent (REVLIMID((R)) or THALIDOMID((R))), and been ... potentially first-in-class, oral anti-cancer agent that inhibits the phosphoinositide 3-kinase ... adult and pediatric tumor types, both as a single agent and in combination with novel therapies. KRX-0401 ...

SLAICO Takes the Medicare Supplement Application Online - Eliminating All Paperwork Offline.

... Insurance Company (SLAICO) for their clients. The agent simply completes the e-application on the secure ... their approval. Within a short 48 hours, the agent can view the decision online. A "first" ... it by regular mail to the Agent, or for the agent to email the application to the client for an ...

Agent Orange Linked to Parkinson's, Heart Disease

... FRIDAY, July 24 (HealthDay News) -- Exposure to agent Orange and other herbicides that were sprayed far ... among soldiers who served in that conflict. agent Orange is made up of compounds known to be ... American forces could fight more effectively; agent Orange was the herbicide used most often to ...

Limited data suggest possible association between Agent Orange exposure

... suggestive but limited evidence that exposure to agent Orange and other herbicides used during the ... be a relationship between Parkinson's disease and agent Orange exposure stems from its review of 16 ... animal studies testing the chemical components of agent Orange for their potential to cause ...

Caltech chemists say antibody surrogates are just a 'click' away

... subunits together. To create a capture agent for a particular protein, the scientists devised ... in which the first subunit of the capture agent is identified, and that unit, plus the protein, ... about a third of the length of the final capture agent the scientists are trying to makeis then ...

Remote-control closed system invented for inserting radio-active atoms inside fullerenes

... is a fullerene that encases a sensitive contrast agent (gadolinium) for MRI applications, including as a diagnostic and therapeutic agent for brain tumors. Dorn and Fatouros at VCU have ... the fullerene with the 177Lu such as a targeting agent (interleukin-13) and an MRI contrast agent," said ...

Urgent(R) PC and Macroplastique(R) Featured in Numerous IUGA 2009 Sessions

... PC, Macroplastique, our 'Gold Standard' bulking agent for the treatment of adult female stress urinary ... "Transurethral Injection OF Bulking agent For The Treatment OF Recurrent Or Persistent ... Macroplastique(R) Implants, a urethral bulking agent for the treatment of adult female stress urinary ...

Purdue researchers create prostate cancer 'homing device' for drug delivery

... support from Endocyte Inc. A radioimaging agent linked to the targeting molecule will be injected ... said. There is currently only one radioimaging agent for prostate cancer approved by the Food and Drug ... are very poor," Low said. "The existing imaging agent is limited because of its large size, which is ...

Lilly Receives Fourth FDA Approval for ALIMTA(R) (pemetrexed for injection)

... received consecutive approvals: it was the first agent to be approved in combination with cisplatin as a ... for curative surgery, and then as a single agent for the second-line treatment of patients with ... indication. ALIMTA is now indicated as a single agent for the treatment of patients with locally ...

Biomarkers predict brain tumor's response to therapy

... tyrosine kinases. It is an investigational, oral agent that is administered once daily. Using a form of ... cediranib, those patients who benefited from the agent and those who did not. "We found that results ... treatment effects in patients treated with this agent combined with standard radiation and ....

New Market Research Study Shows Lung Cancer Treatments Differ Significantly by Both Age and Geography

... with a chemotherapy doublet plus a targeted agent far more common in the US than in Europe. ... doublets most often chosen and whether a targeted agent is concurrently administered," says J.F. ... "The most extensive use of doublets plus targeted agent is in the US, in contrast with Europe and Japan. ...

Mayo Clinic Researchers Say Agent Provides Treatment Option for Women with Hot Flashes

... treatment, for hot flashes. Gabapentin, an agent that has long been on the market to treat pain ... six weeks of treatment, women using a placebo agent reported about a 50 percent decrease in their hot ... all, this study demonstrates that we have another agent to add to the list of medications that offer ...

Sodium channel blocker shows promise as a potential treatment for cystic fibrosis

... results suggest that we have identified a new agent that acts directly on a specific pathway, which ... a specific epithelial sodium channel-blocking agent called GS-9411, which prevents sodium from being ... Concurrent animal studies revealed that the agent enhanced mucous clearance for more than four ...

Mayo Clinic researchers say agent provides treatment option for women with hot flashes

... treatment, for hot flashes. Gabapentin, an agent that has long been on the market to treat pain ... six weeks of treatment, women using a placebo agent reported about a 50 percent decrease in their hot ... all, this study demonstrates that we have another agent to add to the list of medications that offer ...

Women's Digital Imaging of Ridgewood First Private Medical Practice in New York Area to Screen With Breast Specific Gamma Imaging (BSGI)

... function. The patient is injected with a tracing agent that is absorbed by all the cells in the body. ... a special Imaging camera detects the tracing agent and translates it into a digital image of the ... cells absorb a greater amount of the tracing agent than non-cancerous cells, due to their increased ...

Schering-Plough Starts Patient Enrollment in Phase 3 Trial for Acadesine, an Investigational Agent Being Studied for Prevention of Complications From Cardiac Surgery

... Patient Recruitment for Potentially Life-Saving agent KENILWORTH, N.J., May 11 ... potentially first-in-class adenosine regulating agent (ARA). Acadesine was licensed from PeriCor ... with the CABG procedure. In addition, an agent that can be shown to reduce surgical ...

4-in-1

... Cheon have developed the basis for a four-in-one agent that can detect, target, and disable tumor cells ... cells. The magnetic particles act as a contrast agent for magnetic resonance imaging, and the ... an aide for transport, they are also a contrast agent for MRI. This reveals where the tumors are, ...

Agent Orange Exposure Tied to Prostate Cancer Return

... -- U.S. male military veterans exposed to the agent Orange herbicide/defoliant are at increased risk ... Of those, the 206 men who'd been exposed to agent Orange were nearly 50 percent more likely to ... of cancer aggressiveness -- to double among the agent Orange-exposed veterans with recurrent cancer, ...

Targeted agent shows promise in biliary cancer study

... COLUMBUS, Ohio An experimental agent has shown promising results in people with ... it provides a strong rational for developing this agent further in larger trials either alone or in ... to be well tolerated with mild toxicities. The agent belongs to a class of drugs called protein kinase ...

Former National Century Financial Enterprises CEO Sentenced to 30 Years in Prison, Co-owner Sentenced to 25 Years in Prison for Conspiracy, Fraud and Money Laundering

... is immediately and negatively impacted," Special agent in Charge of the Internal Revenue Service's ... at any level." FBI Cincinnati Special agent in Charge Keith L. Bennett noted the significant ... Mooney; and Immigration and Customs Enforcement agent Celeste Koszut. Assistant U.S. Attorney Douglas ...

Cleveland Trials Set In Nephrogenic Systemic Fibrosis (NSF) Gadolinium MRI Side Effects Cases

... litigation involving gadolinium MRI contrast agent side effects and nephrogenic systemic fibrosis . ... litigation involving gadolinium MRI contrast agent side effects and nephrogenic systemic fibrosis ... Federal Court trials of gadolinium MRI contrast agent cases involving nephrogenic systemic fibrosis ...

Abbott Announces Required Offer to Repurchase Convertible Senior Subordinated Notes of Its AMO Subsidiary

... Convertible Notes must be delivered to the Paying agent at or prior to the Expiration Time. Holders that ... submit a physical election notice to the Paying agent if such holders comply with the transmittal ... available through the Paying Agent. The Paying agent can be reached at (800) 934-6802. This press ...

United States Files Complaint Against Forest Laboratories for Allegedly Violating the False Claims Act

... Michael J. Sullivan; Warren T. Bamford, Special agent in Charge of the Federal Bureau of Investigation ... Boston Field Division; Susan J. Waddell, Special agent in Charge of Health and Human Services -- Office ... of Investigations; Mark Dragonetti, Resident agent in Charge of the Food and Drug Administration, ...

Dosing Begins in Phase 1 Clinical Study Evaluating NKTR-105 in Cancer Patients With Refractory Solid Tumors

... Docetaxel is a versatile chemotherapy agent currently approved by the FDA for use in five ... a number of cancer types, both as a single agent and in combination with other therapies. ... sustained exposure of this potent anti-mitotic agent to constantly dividing cancer cells." About ...

Tracon Pharmaceuticals to Present Clinical Stage Programs at AACR 2009

... of commonly used antimetabolite and alkylating agent chemotherapies. The molecule is currently being studied as an oral agent in combination with pemetrexed (Alimta(R)) and as an i.v. agent in combination with temozolomide (Temodar(R)). ...

High and Super-High Potency Topical Corticosteroids Will Remain Decision Resources' Clinical Gold Standard Through 2017 for the Treatment of Atopic Dermatitis

... A Once-Daily Topical agent With a Novel Mechanism of Action and Efficacy ... Therapy also finds that a once-daily topical agent with a novel mechanism of action and efficacy ... On the other hand, in Europe, such an agent would earn a 25 percent patient share, according ...

Senior Market Sales Offers Discounted E&O Insurance for Agents

... in different product lines. For example, an agent who specializes in health insurance -- including ... Medicare Solutions for Senior Market Sales. "An agent who only sells Medicare products doesn't have to ... Senior Market Sales. For example, a health agent working exclusively with Senior Market Sales can ...

CRi to Distribute VisEn Medical's Portfolio of Fluorescence In Vivo Imaging Agents and Labels in North America

... partnering with VisEn around their unparalleled agent products, and we look forward to continually ... VisEn also offers its specialized in vivo agent labeling platforms, including its proprietary ... fluorescence labeling dyes for custom in vivo agent development, and its NanoSpark (R) in vivo ...

Better MRI scans of cancers made possible by TU Delft

... scan depends partly on the ability of this agent to 'search out' the tumour and induce contrast. ... Kristina Djanashvili has developed a new contrast agent with enhanced tumour affinity and contrast ... sooner and visualised more accurately. The new agent is a compound incorporating a lanthanide chelate ...

Micro-Bubble Echo Contrast Procedures Continue to Rebound in October 2008

... their institutions. A micro-bubble echo contrast agent is administered intravenously and used for ... being performed and cardiac ultrasound contrast agent and pharmacological stressing agent usage. About the U.S. ...

Glowing Substance Lights Up Cancer in Mice

... compounds, our compound consists of a targeting agent and a fluorescing agent that act independently. We can target the fluorescing agent to different types of cancer cells by using any ...

QLT announces commencement of tender offer

... Communications Inc. will serve as information agent and Computershare Investor Services Inc. will ... tender offer may be directed to the information agent at (866) 733-9452. Any questions regarding the tender offer may be directed to the information agent at the telephone number above, to Goldman Sachs ...

HLTH Corporation Announces Preliminary Results of Its Tender Offer

... for the tender offer is Citi. The Information agent for the tender offer is Innisfree M&A ... and information, please call the Information agent toll free at 1-888-750-5834 or the Dealer Manager ... INNISFREE M&A INCORPORATED, THE INFORMATION agent FOR THE TENDER OFFER, TOLL-FREE AT ....

Leading Healthcare Provider Signs Agreement With UCN for inContact

... order to unify reporting capabilities and track agent availability more efficiently. The customer plans ... between their multiple centers based on agent availability. inContact also helps manage ... and CTI (Computer Telephony Integration). agent performance optimization features ...

DFMO may affect Barrett's esophagus

... is very preliminary and further study of this agent in a larger number of patients is needed," said ... the drug and a possible cancer risk marker. The agent works by inhibiting an enzyme in polyamine ... warrants further evaluation as a chemopreventive agent in patients with Barrett's esophagus and mucosal ...

Keryx Biopharmaceuticals' KRX-0401 (Perifosine) Data Selected for Oral Presentation at the 50th Annual Meeting of the American Society of Hematology

... efficacy of KRX-0401, both as a single agent and in combination with other approved agents, in ... potentially first-in-class, oral anti-cancer agent that modulates Akt and a number of other key ... variety of tumor types. KRX-0401 has shown single agent partial responses in renal cell and ...

Companies Turn to Click-to-Chat Technology to Reduce Operating Expense and Enhance Customer Service

... customer service center. "When a voice agent completes a call, she'll turn to her colleagues ... abandonment of the Chat session. For example, an agent can "push" to the customer ... snippets such as: "Your customer service agent is researching your question and will be right ...

CHEST 2008: Featured abstracts

... (Wednesday, October 29, 1:00 PM EST) The novel agent cobinamide could be an ideal antidote for cyanide ... of cobinamide make it potentially an ideal agent for treatment of mass casualty cyanide exposures. ... procedure involving the injection of a hardening agent into the upper palate, may help to reduce simple ...

Sugammadex Study First to Show Rapid Reversal of Profound Rocuronium-Induced Muscle Relaxation is Possible

... muscle relaxation than the conventional reversal agent neostigmine. Importantly, this is the first ... Sugammadex is a novel selective relaxant binding agent that works in an entirely new and unique way to ... study demonstrates that sugammadex is the first agent to permit rapid reversal of a profound level of ...

NeoVista Presents Anatomic Outcomes of Novel Wet AMD Therapy at 2008 American Society of Retina Specialists Meeting

... monthly intravitreal injections of an anti-VEGF agent for an indefinite period of time. In contrast, ... two injections of an anti-VEGF agent are delivered one month apart to maximize the ... with two intravitreal injections of an anti-VEGF agent (bevacizumab), which are delivered to maximize ...