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Acetaminophen in Medical News

Docs Say No to Pulling Drugs Containing Acetaminophen off the Market

... (82%) do not believe that drugs containing acetaminophen should be pulled off the market. (Logo: ... the FDA's warnings and concerns regarding the acetaminophen have not affected their prescribing habits. ... More likely to prescribe products containing acetaminophen 1% ...

Cadence Pharmaceuticals Announces Priority Review and Acceptance of NDA Submission for Acetavance(TM) for Treatment of Acute Pain and Fever

... than 53 million patient exposures to intravenous acetaminophen in countries outside the United States. ... intravenous formulation of acetaminophen. acetaminophen is the most widely used medication for the ... Europe and other parts of the world. Intravenous acetaminophen is approved in approximately 80 countries, ...

Viles & Beckman, LLC: Stop Your Headache NOT Your Liver

... MYERS, Fla., July 2 /PRNewswire-USNewswire/ -- acetaminophen is an ingredient found in many over-the-counter ... pain and reduce fever. Many people refer to acetaminophen by a brand name, Tylenol and prescription brand ... the maximum single dose to 650 milligrams. acetaminophen overdoses are the leading cause of liver damage ...

Pain Medicine Experts Recommend Safe and Responsible Use of Acetaminophen

... Administration (FDA) to put new restrictions on acetaminophen this week, physician leaders from the ... supports the safe and responsible use of acetaminophen both in over-the-counter and prescription ... AAPM recognizes that analgesics that combine acetaminophen and an opioid do pose additional risk for ...

If 2 Painkillers Are Banned, What Next?

... and ibuprofen. Vicodin and Percocet combine acetaminophen with an opiate narcotic in one pill. Vicodin ... to treat moderate to severe pain. But acetaminophen is the active ingredient in such popular ... Excedrin. And consumers may also not know that acetaminophen is present in many other over-the-counter ...

FDA Panel Urges Ban on Vicodin, Percocet

... drugs like Vicodin or Percocet, which combine acetaminophen with an opiate narcotic, should be banned, and ... can result from a lack of consumer awareness that acetaminophen -- which is easier on the stomach than such ... to problems with prescription opiate combination acetaminophen products, whereas the number of deaths clearly ...

FDA Panel Urges Tough Controls on Acetaminophen Painkillers

... to lower the maximum dose of over-the-counter acetaminophen -- the key ingredient in Tylenol, Excedrin and ... can result from a lack of consumer awareness that acetaminophen -- which is easier on the stomach than ... to problems with prescription opiate combination acetaminophen products, whereas the number of deaths clearly ...

FDA Advisers Urge Smaller Doses of Acetaminophen

... to lower the maximum dose of over-the-counter acetaminophen -- the key ingredient in Tylenol, Excedrin and ... can result from a lack of consumer awareness that acetaminophen -- which is easier on the stomach than ... health risks. And consumers may not know that acetaminophen is present in many over-the-counter products, ...

FDA Advisers Recommend Smaller Doses of Acetaminophen

... lowering the maximum dose of over-the-counter acetaminophen -- the key ingredient in Tylenol, Excedrin and ... can result from a lack of consumer awareness that acetaminophen can cause such injury. Also, many people may take ... health risks. And consumers may not know that acetaminophen is present in many over-the-counter products, ...

Painkillers May Be Good for the Prostate

... NSAID users in her study as well. Men taking acetaminophen also were included in Singer's study, and they ... levels. But, because the number of men who took acetaminophen was low, the result was not great enough to be ... and other problems, Singer warned. And too much acetaminophen has been associated with liver toxicity. The ....

Buster Brands Launches Natural Alternatives to Acetaminophen Pain Killers

... warnings and dose limits for drugs containing acetaminophen in both the prescription and over-the-counter (OTC) versions. Negative publicity for acetaminophen has been building for several years now, which ... warnings and dose limits for drugs containing acetaminophen in both the prescription and over-the-counter ...

FDA Report Urges Tougher Acetaminophen Warning

... and limits on doses for both prescription acetaminophen and over-the-counter acetaminophen, best known as ... can result from a lack of consumer awareness that acetaminophen can cause such injury. Also, many people may take ... health risks. And consumers may not know that acetaminophen is present in many over-the-counter products, ...

FDA Adds New Label Warnings to Over-the-Counter Painkillers

... on all their over-the-counter products containing acetaminophen (best known as Tylenol), and on all non-steroidal ... apply to any over-the-counter drug that contains acetaminophen and NSAIDs mixed with other drugs, Holman said. ... to raise awareness of potential liver damage from acetaminophen and the potential for stomach bleeding from ...

Acetaminophen, Cholesterol Drugs May Help Fight Stroke

... 14 (HealthDay News) -- Two new studies find that acetaminophen and statins can be of great benefit in either ... from normal (98.6 F) to 102.2 F who received acetaminophen soon after the onset of a stroke fared better ... the second study, focusing on the pain reliever acetaminophen -- best known in the United States under the ...

NeurogesX Reports Fourth Quarter and Year-End 2008 Results

... opportunities to advance its opioid and acetaminophen prodrugs. NGX-9674 and ... NGX-1576, a novel prodrug coupling acetaminophen to a liver protectant, has been evaluated in ... pre-clinical compounds which are prodrugs of acetaminophen and various opioids. The company has evaluated ...

Acute gastric injury due to high-dose analgesics?

... side effects of NSAIDs are well documented and acetaminophen is accepted to be a safe drug for the ... of short-term, especially high-dose NSAID and acetaminophen use have not been studied adequately. A ... the gastrointestinal side effects of high dose acetaminophen and ....

Painkillers Boost Muscle Mass Among Weight-Training Elderly

... Daily dose of ibuprofen, acetaminophen upped growth by 40% to 60%, study found ... News) -- A daily dose of either ibuprofen and acetaminophen appears to boost both muscle mass and strength ... on the short-term impact of ibuprofen and acetaminophen on muscle metabolism among young men and women ...

Scientific poster abstracts from the 24th annual meeting of the American Academy of Pain Medicine

... Patients 214 Efficacy and Safety of IV acetaminophen in the Treatment of Pain Following Vaginal ... 215 Pharmacokinetics, Efficacy, and Safety of IV acetaminophen in the Treatment of Pain Following Total Hip ... Study 216 Efficacy and Safety of IV acetaminophen in the Treatment of Pain Following PrimaryTotal ...

Caffeine Plus Acetaminophen Toxic for Some

... News) -- Very high doses of caffeine and acetaminophen (such as Tylenol), taken together, could lead to ... an enzyme that can form a toxic metabolite of acetaminophen in such a way that it increases the formation of ... In the study, Nelson's team tested the effects of acetaminophen and caffeine on E. coli bacteria. These ...

Study examines liver transplantation after drug induced acute liver failure

... induced acute liver failure is very rare, but can be life-threatening. acetaminophen is the most common cause, accounting for nearly half of cases in adults, ... drug groups causing liver failure that required transplantation were acetaminophen (40 percent), antituberculosis drugs (8 percent), antiepileptics (7 ...

Cadence Pharmaceuticals Announces Positive Topline Results of Phase III Clinical Trial of Acetavance in Laparoscopic Surgery

... with acute postoperative pain or fever demonstrated that intravenous acetaminophen has a hepatic safety profile comparable to placebo, with liver function ... as well as reports of adverse events from countries where intravenous acetaminophen is already approved and commercialized, may indicate that the prevalence ...

Ethnicity Plays Role in Parents' Treatment of Childhood Fever

... all parents tended to overtreat fever and reported giving their children acetaminophen and ibuprofen more often than recommended. The type of fever prescription ... fatigue and irritability. Important things to remember include: acetaminophen should be given every four to six hours with no more than five doses ...

Cadence Pharmaceuticals Reports Fourth Quarter and Full Year 2007 Financial Results and Provides Corporate and Clinical Program Overview

... our two product candidates, Acetavance(TM), an intravenous formulation of acetaminophen for the treatment of pain and fever, and Omigard(TM), a topical ... anti-pyretic action of Acetavance compared to orally-administered acetaminophen in 81 patients at one U.S. clinical trial site. -- Cadence has initiated ...

Labopharm Initiates Phase III Clinical Trial for Twice-Daily Formulation of Tramadol-Acetaminophen

... day. Labopharm believes that by metering the release of both tramadol and acetaminophen from a single tablet using its Contramid(R) controlled-release technology, ... offer the analgesic strength of tramadol and the rapid analgesia of acetaminophen in a single tablet. Tramadol-acetaminophen combination products were first ...

Cadence Pharmaceuticals Announces Topline Results of Two Phase III Clinical Trials of Acetavance(TM)

... pivotal, Phase III clinical trials of Acetavance(TM), a formulation of acetaminophen for intravenous use. One of these clinical trials did not meet its primary ... study of the antipyretic efficacy and safety of intravenous acetaminophen over a six-hour period. In this study, 60 adult patients at one United ...

Treatment with NAC is associated with better outcomes for children with liver failure

... N-acetylcysteine (NAC) on children with acute liver failure not caused by acetaminophen poisoning has found that the treatment was associated with a shorter ... ). Acute liver failure in children is rare but can be fatal. acetaminophen poisoning is a common cause, and is treated with NAC, which acts as an ...

Harvard Health Letter Special Section Features the Body's Unsung Marvels: The Feet

... this special issue: How Your Feet Work -- and Three Steps for Keeping Them Healthy Also in this issue:   All about shellfish acetaminophen overdose The Harvard Health Letter is available from Harvard Health Publications, the publishing division of Harvard Medical School, for $29 per ...

Nanotechnology Transforms Pain Relief

... pain reliever like MyOmega(R) is ideal because it offers a healthy alternative to pills and pain relief patches. Seemingly harmless drugs like acetaminophen and Methyl Salicylate have potentially fatal effects. Acetaminophen, the active ingredient in Tylenol(R) and other commonly prescribed pain ...

Zogenix and Astellas Enter Exclusive Co-Promotion Agreement in the US for Newly Approved Sumavel(TM) DosePro(TM)

... received FDA approval in July 2009. The company's pipeline also includes ZX002, a novel oral controlled-release formulation of hydrocodone without acetaminophen for the treatment of chronic pain, expected to enter Phase 3 clinical trials in 2009. Zogenix also plans to license the patented DosePro needle-free ...

NeurogesX Announces Resignation of Bruce A. Peacock from Board of Directors

... the timing of entering Phase 2 development. NeurogesX' early stage product pipeline includes pre-clinical compounds, which are prodrugs of acetaminophen and various opioids. The company has evaluated these compounds in vitro and in vivo and is currently seeking development partners for these ...

FDA Mandates Tougher Warnings for Pain Pills

... generic drug makers. Last week, an FDA advisory panel recommended that the popular prescription painkillers Vicodin and Percocet, which combine acetaminophen with an opiate narcotic, be banned. Darvocet contains acetaminophen. More information The U.S. Food and Drug Administration has more on ...

NeurogesX and Astellas Enter Commercialization Agreement for Qutenza(TM)

... the timing of entering Phase 2 development. NeurogesX' early stage product pipeline includes pre-clinical compounds, which are prodrugs of acetaminophen and various opioids. The company has evaluated these compounds in vitro and in vivo and is currently seeking development partners for these ...

Artificial liver may extend lives

... each year, including those with chronic liver diseases like hepatitis, as well as those whose livers were damaged, such as by taking too much acetaminophen pain medicine. If not treated effectively and promptly -- usually by transplantation -- patients experience organ failure, bleeding, coma and death. ...

Medical Director of Renowned Los Angeles Jewish Home Offers Advice to Seniors on Avoiding Swine Flu

... a doctor are always necessary with older patients," Smith said. Besides taking it easy, he encourages seniors to drink lots of fluids and take acetaminophen for pain. "Wash your hands frequently and thoroughly, and cover your mouth when you cough." Though it is not known exactly how severe this ...

Actress and Mom Alison Sweeney Teams Up With the American Pharmacists Association to Help Fellow Allergy Sufferers Find Relief This Spring

... shelves as well as behind the pharmacy or service counter. McNeil Consumer Healthcare is most widely recognized for the complete line of TYLENOL(R) acetaminophen products, the leading pain reliever brand in the adult and pediatric categories. The TYLENOL(R) product line consists of hundreds of products across ...

Labopharm reports results for Phase III study on twice-daily tramadol-acetaminophen formulation

... DDSS ) today announced the results of its recently completed North American Phase III clinical trial for its twice-daily formulation of tramadol and acetaminophen (study 06CCL3-001). Study 06CCL3-001 was a multi-centre, randomized, double-blind, parallel-arm study that compared the efficacy and safety of ...

CMEFirst Presents State-of-the-Art Arthritis CME Symposium

... complications associated with the long term use of Vioxx and other "COX-2" analgesics. This is remarkable since simple analgesics such as acetaminophen (Tylenol(R)) and the NSAIDs are the single most commonly used and prescribed category of drug on a world wide basis. Hence, to address these ...

Par Pharmaceutical Reports Fourth Quarter and Full Year 2008 Results

... volume and pricing declines included fluticasone, propranolol, cabergoline, various amoxicillin products, ranitidine syrup, tramadol HCl and acetaminophen tablets driven by Par's exit from the market, and lower royalty payments of ondansetron tablets, among others. These decreases were offset by higher ...

An Orthopaedic Roadmap for Osteoarthritis of the Knee

... symptomatic OA of the knee receive one of the following analgesics for pain unless there are contraindications to this treatment: acetaminophen (not to exceed 4 grams per day) Non-steroidal anti inflammatory drugs (NSAIDs) Intra-articular corticosteroids (for short term pain ...

Children's Sugar-Free, Dye-Free ZYRTEC(R) Allergy Syrup Now Available

... of well-known and trusted over-the-counter (OTC) products. McNeil Consumer Healthcare is most widely recognized for the complete line of TYLENOL(R) acetaminophen products, the leading pain reliever brand in the adult and pediatric categories. The TYLENOL(R) product line consists of hundreds of products across ...
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