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ANTIGEN in Medical News

PharmAthene, Inc. Announces $19.3 Million Private Placement of Convertible Notes and Common Stock Warrants

... - a second generation recombinant protective antigen (rPA) anthrax vaccine Third generation rPA ... agents RypVax(TM) - a recombinant dual antigen vaccine for plague For more ... Proposals for an Anthrax Recombinant Protective antigen (rPA) Vaccine for the Strategic National ...

CEL-SCI Expands Testing of Its Vaccine to Determine Efficacy Against More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... proprietary L.E.A.P.S. technology (Ligand Epitope antigen Presentation System) to determine its efficacy ... to induce and elicit protective immunity and antigen specific antibody production in animal models. ... constructs are chimeric peptides which combine antigen specificity with immune response modulation. ...

Early Detection of Melanoma Plus Regular Skin Exams is Vital For Beating Disease

... targeted antibody known as MART-1 (Melanoma antigen Recognized by T cells), which improves the speed ... to test a vaccine known as the MAGE-A (melanoma antigen - family A) vaccine that would be used as an ... types of stage III and IV melanoma. MAGE is an antigen that exists in every cell in the body, but it is ...

PharmAthene Reports Year End 2008 Financial Results

... novel second generation recombinant protective antigen vaccine candidate, has been selected by the ... of 25 million doses of a recombinant protective antigen vaccine for the Strategic National Stockpile. ... - a second generation recombinant protective antigen (rPA) anthrax vaccine Valortim(R) - a ...

American Urological Association Statement in Support of Prostate-Specific Antigen Testing

... Journal of Medicine about prostate-specific antigen (PSA) testing. The American Urological ... the two studies about prostate-specific antigen (PSA) testing recently published in the New ... Best Practice Statement about prostate-specific antigen testing that will be unveiled during our upcoming ...

Polymedco Introduces Point of Care Test for Recurrent Bladder Cancer Detection

... BTA stat(R) Test Detects Bladder Tumor Associated antigen in Urine CORTLANDT MANOR, N.Y., Jan. 29 ... detect the presence of bladder tumor associated antigen in urine. It is a single-step, rapid immunochromatographic assay for bladder tumor-associated antigen in voided urine. The specificity of the BTA ...

Inverness Medical Innovations Announces 4th Generation Rapid HIV Test - Determine(TM) HIV-1/2 Ag/Ab Combo

... which enables simultaneous detection of HIV p24 antigen (Ag) and antibodies (Ab) for HIV-1 and HIV-2 in human serum, plasma or whole blood. The p24 antigen is present during the first few weeks of HIV ... to aid in early HIV detection. By targeting p24 antigen as well as the HIV antibody response, Determine ...

Crucial factors in lymphoma development and survival discovered

... development of tumors both in the presence of an antigen and when no antigen was present. When no antigen was present, the mice developed a lymphoma ...

Targeted Anticancer Drugs - In Vitro Assessment and Non-Invasive Imaging of Patient and Tumor Status Will Determine Clinical and Commercial Success

... 1B1 (CYP1B1); cytotoxic T lymphocyte-associated antigen 4 (CTLA4); dihydrofolate reductase (DHFR); ... cell death-1 (PDCD1); prostate specific antigen (PSA); prostate stem cell antigen (PSCA); prostate-specific membrane antigen (PSMA); proteasome; protein kinase A type I ...

OHSU Cancer Institute finds that drug stimulated immune system in prostate cancer

... Last year his cancer count, or prostate specific antigen (PSA), was at a high level -- an indicator that ... responding to any drugs. A prostate-specific antigen test measures the amount of prostate-specific antigen in the blood. PSA is released into a man's blood ...

Immunotherapy: enlisting the immune system to fight cancer

... stage IVb. Listeria monocytogenes infects antigen presenting cells (APCs) a very special piece of ... it and to cause it to secrete a tumor-specific antigen fused to a listerial protein, which makes it more ... we focus a very strong immune attack against the antigen in question, which is typically specific to a ...

Iomai Wins Department of Defense Grant to Develop a Stable, Patch-Based Anthrax Vaccine

... in an effort to formulate a dry version of antigen that can be combined with an Iomai adjuvant on a ... limitation, the supply of anthrax antigen from Avecia Biologics Ltd.; that pre-clinical ... that Iomai's dry patch formulation of the anthrax antigen will be stable and capable of being stored and ...

FDA Clears Cellsearch(TM) Circulating Tumor Cell Test for Monitoring Metastatic Prostate Cancer Patients

... parameters, such as prostate specific antigen (PSA) measured in MPC patients. A decrease in the ... combination of CTC analysis and prostate specific antigen (PSA) assessment may provide the most accurate ... prognosis much earlier than the prostate specific antigen serum tumor marker test. In August 2004, a ...

Novel molecules developed at UB can boost vaccine potency

... small amount of LT-IIa or LT-IIb with an existing antigen and dripping the mixture into a mouses nose ... In contrast, immunizing the mouse with only the antigen generates a much lower level antigen-specific ... through the nose, all I have to do is dry the antigen and my adjuvant. When I get to the middle of ...

Resisting lung cancer recurrence

... a general way, and the other component, the tumor antigen in this case, the MAGE-A3 antigen directs the immune response specifically against ... showed that a cancer vaccine based on the tumor antigen NY-ESO-1 stimulated an immune response in women ...

Serum carcinoembryonic antigen level can reflect adrenal adenoma

... Unexpectedly, the serum carcinoembryonic antigen (CEA) level was elevated. Fluorodeoxyglucose ... of cortisol, catecholamines and carcinoembryonic antigen were significantly elevated in the drainage vein ... The cortisol, catecholamine and carcinoembryonic antigen levels normalized immediately after surgery. ...

Why Obese Men Post Lower PSA Levels

... undergo a PSA blood test that looks for an antigen made by the prostate that helps it function. The antigen leaks into the bloodstream at a steady rate, and ... PSA levels are lower in larger men is because the antigen gets diluted in larger volumes of blood. "It's ...

Planet Technologies Announces Completion of Antigen Laboratories Acquisition

... existing allergen avoidance product business. The antigen transaction continues to deliver on our strategy ... Chief Executive Officer and President of Planet. antigen will operate as a wholly owned subsidiary of ... doses by subcutaneous injections ("SCIT"). antigen provides allergenic extracts to over ...

PharmAthene and Medarex Announce Additional $0.8 Million U.S. Government Appropriation for Continued Development of Anthrax Therapeutic Valortim(TM)

... protein component known as the anthrax protective antigen (PA) of the lethal toxin complex produced by the bacterium. The anthrax protective antigen is believed to initiate the onset of the illness ... Valortim is designed to target anthrax protective antigen and protect the cells from damage by the anthrax ...

PSA Testing Still Valuable for Prostate Cancer

... key is whether the level of prostate-specific antigen is rising rapidly SUNDAY, Oct. 7 ... have debated the value of the prostate-specific antigen test to determine a man's risk for prostate ... seems to be emerging -- it's not the level of the antigen in the blood that helps predict the likelihood of ...

T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells

... an artificial T cell receptor called a chimeric antigen receptor -- designed to specifically bind to ... on the surface of B cells and B cell cancers. antigen receptors are what allow T cells, in combination ... immune system-related genes, creates the chimeric antigen receptor protein called 19-28z, which does not ...

Planet Technologies Announces Agreement to Acquire Antigen Laboratories

... and sale of allergen avoidance products, and antigen Laboratories, Inc. (Antigen), a privately-held ... will acquire all of the outstanding equity of antigen for $10 million, plus the payment of certain ... 4,000 physicians in the United States annually. antigen will operate as a wholly owned subsidiary of ...

Ferring Pharmaceuticals Announces Trade Name FIRMAGON(R) (degarelix for injection) for Advanced Prostate Cancer Treatment

... with 96.4 percent for leuprolide. In addition, prostate-specific antigen (PSA) levels were lowered by 64 percent two weeks after administration of ... testosterone levels.(4) FIRMAGON also reduces levels of prostate-specific antigen (PSA). Unlike luteinizing hormone-releasing hormone (LHRH) agonists, such ...

PATH Malaria Vaccine Initiative and Crucell to test new malaria vaccine approach

... common cold and other mild respiratory infections) to deliver a malaria antigen to the immune system. Dr. Jaap Goudsmit, Chief Scientific Officer at ... has been seen to date from the circumsporozoite protein (CSP), the only antigen that has proven to be protective against malaria in controlled challenge ...

Bcl6 gene sculpts helper T cell to boost antibody production

... lots of antibodies. In the adaptive immune system, B cells present an antigen - a distinctive piece of an invading bacterium or virus - to T cells. The bound antigen converts a nave T cell to a helper T cell that secretes cytokines which ...

Tips from the journals of the American Society for Microbiology

... available to reach mass populations and they must include the minimal antigen dose (substance that promotes the generation of antibodies) to result in ... to improve the immune response) in vaccine development may lower the antigen dose required and ultimately ease the demand on vaccine supply during a ...

Novel DNA vaccine leads to kidney damage prevention in systemic lupus erythematosus models

... regulating the immune system) has potential as a novel therapy to induce antigen specific tolerance and may help to prevent kidney damage in patients with ... in combination with IL-10 and another group vaccinated with the same antigen and IFN-gamma, both signaling molecules involved in the immune process. ...

Courageous Cancer Survivors Honored at Intergraph(R) Garden of Hope

... doctors discovered Wayne had prostate cancer. His Prostate-Specific antigen (PSA) levels had been consistently high for about a year, and biopsies ... During a routine exam in March 2008, Garth's Prostate-Specific antigen (PSA) test levels rated higher than normal. Given his family history of ...

Immune exhaustion driven by antigen in chronic viral infection

... of these experiments allowed us to answer a broad question: the role of antigen in driving exhaustion." When injected with LCMV, the altered mice had ... and more exhausted T cells. This contrast demonstrates how the level of antigen present is the motor behind immune exhaustion during the chronic ....

More Cancer Tests Mean More False-Positive Results

... along with a three- or five-year follow-up; annual tests for cancer antigen 125 (CA-125) and a transvaginal ultrasound yearly to check for ovarian ... exam to check for prostate cancer in men, as well as a prostate-specific antigen test. No information was included on mammography for women in either ...

Inverness Medical Innovations Launches New FDA Cleared C. DIFF QUIK CHEK COMPLETE(TM) Rapid Test

... of cross contamination and widespread outbreaks. The C. difficile antigen glutamate dehydrogenase (GDH) used in the test is common to all strains of ... offer a wide range of testing formats for the detection of C. difficile antigen glutamate dehydrogenase and toxins A and B that can suit all laboratory ...

Dendritic cells ensure immune tolerance

... for this job. They present the T cells with various antigens, and if an antigen matches a receptor, then that T cell will trigger an immune response from ... this tactic lies an element of danger to the organism: what happens if the antigen is not foreign, but originates from the body's own tissue instead? A ...

Study Links Blood Type and Pancreatic Cancer

... protein "backbone" called the H antigen. In people with type O blood, the antigen has no sugars attached to it. Previous studies have found that normal pancreas cells have blood-type antigen patterns that differ from those in pancreatic tumor cells, leading to ...

Ferring Pharmaceuticals Announces Immediate Availability of Degarelix for the Treatment of Advanced Prostate Cancer

... for leuprolide. Study findings also showed that prostate specific antigen (PSA) levels were lowered by 64 percent two weeks after administration of ... levels.(4) Degarelix also reduces levels of prostate-specific antigen (PSA). Unlike LHRH agonists, such as leuprolide, an established treatment ...

PSA Tests Not Race-Specific, Study Finds

... issue of Cancer Prevention Research . High levels of prostate-specific antigen (PSA), which cells in the prostate produce, often indicates an increased ... The U.S. National Cancer Institute has more about prostate-specific antigen levels . -- Kevin McKeever ...

A new light on tumor immunotherapy for gastric cancer

... Dendritic cells (DCs) are professional antigen presenting cells (APCs) that both initiate and modulate the immune response. DCs are cells in the pathway of antigen capture and presentation to T cells, with the unique ability to directly ...

New intranasal influenza vaccine triggers robust immunity with significantly less antigen

... study by NanoBio Corporation. The new vaccine used only half the standard antigen dose to produce this effect. Results of the study are being presented ... a paradigm shift in vaccinology. It can be used to safely deliver multiple antigen types directly into the lining of the nasal mucosa, which is rich in ...

CEL-SCI Presents Favorable Data for Leaps Vaccine Technology at Prestigious Immunology Conference

... Immunology, demonstrated that immunization with a LEAPS (Ligand Epitope antigen Presentation System) vaccine altered the immunological hormone (cytokine) ... that were examined include one that was previously shown to provide antigen specific protection and cellular immunity against herpes simplex virus ...

NYP/Weill Cornell physician-scientists present latest cancer findings at ASCO meeting

... Phase II trial of 177Lutetium radiolabeled anti-prostate-specific membrane antigen (PSMA) monoclonal antibody J591 in patients with metastatic ... metastatic prostate cancer with rapidly increasing prostate specific antigen (PSA) levels. Following only one dose of the J591 antibody loaded with the ...

Radiation Improves Survival for Advanced Prostate Cancer

... prostate, or no radiation until their blood levels of prostate-specific antigen rose. Prostate-specific antigen (PSA) is a protein produced by the cells in the prostate; because PSA can ...
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