Surrogate markers
... outcome or end point . [1]
Surrogate
markers are used when it is unethical to look for the end ... for the end point. The measurement of surrogate
markers provides a way to test the effectiveness of a ... clinical trials that show a benefit to surrogate
markers instead of to end points.
A commonly used ...
Hematopathology
... lymphomas . The hematopathologist uses immunohistochemistry and flow cytometry , techniques using antibodies to specific lymphocyte surface
markers , to determine the type of lymphoma in the pathology specimen .
Notes
^ Jaffe, ES, Harris, NL, Stein, H., and Vardiman, JW, ...
Pathology
... contains an infiltrating ductal carcinoma of the breast. A pathologist will use immunohistochemistry and fluorescent in-situ hybridization to detect
markers which determine the optimal chemotherapy regimen for this patient.
Main article: Anatomical pathology
Anatomical pathologists ...
Predictive medicine
... The goal of predictive medicine is to identify biological
markers in order to enrole individuals at high risk for developing a disease in special early detection trials. Different approaches exist to develop ...
Sexual orientation and medicine
...
^ http://www.baphr.org/about/default.asp
^ Hamer, Hu, Magnuson, Hu and Pattatucci (1993) A linkage between DNA
markers on the X chromosome and male sexual orientation. Science 261(5119): pp. 321-7.
^ Healthy People 2010, 2nd ed. "A Systematic Approach to Health ...
Thymocyte
... for both CD4 and CD8). The final stage in maturation is the single positive stage (positive for either CD4 or CD8).
Stage
Defining surface
markers
Location
Significant events
Double negative 1 or ETP (Early T lineage Progenitor)
Lineage- CD44 + CD25 - CD117 +
cortex
-
...