... the thymus . It causes transcription of a wide selection
of organ-specific genes. This reduces the threat ... autoreactive T cells by the process of negative selection
if they are too reactive to self.
It is mutated ... Liston, A. et al. (2003) Aire regulates negative selection
of organ-specific T cells. Nat Immunol 4 (4), ...
... . The processes of beta-selection, positive selection
and negative selection
shape thymocytes into a peripheral pool of T ...
2.1 Thymus Settling
2.2 Beta selection
... AIRE .
After exposure to self antigens, T cells and B cells become immunologically tolerant (non-reactive) in a number of ways :
( apoptosis )
Receptor editing (changing the specificity of the autoreactive cell) 
Division to a ...
... Main article: Clinical pathology
Pathogenic organisms are grown from patient specimens in clinical microbiology labs, allowing selection
of the correct antibiotics
Clinical pathology , also known as laboratory medicine , is the medical specialty concerned with diagnosing ...
... at university is 5 years (4 if the student already holds a degree). Amongst some institutions and for some students, it may be 6 years (including the selection
of an intercalated BSc - taking one year - at some point after the pre-clinical studies). This is followed by 2 Foundation years afterwards, namely ...