Virulence in Biological Technology

Quick microchip test for dangerous antibiotic resistant bacteria

... a test chip which can accurately identify 56 virulence genes in the diarrhoea-causing Escherichia coli ... surveillance studies to monitor the way genes for virulence and antimicrobial resistance are spread in the ... unique and previously unknown combinations of virulence genes, whose significance still needs to be ...

The Plasmodium vivax genome provides new routes and challenges in the global fight against malaria

... from this centre have contributed their experience in studying the virulence of the parasite in order to validate and analyse the data obtained in the ... field when they discovered the largest family of genes controlling the virulence of this parasite in a study also published in Nature in 2001. The ...

Scientists develop strategy to rapidly describe outbreak strains with next-generation DNA sequencing

... attack, rapid identification of the genetic changes responsible for virulence or drug resistance is essential to mounting an effective response. ... to identify immediately the genetic determinants responsible for modified virulence or transmission, explains La Scola. The aim of this work was to evaluate ...

Isis Announces Equity Investment in Ibis Biosciences Subsidiary by Abbott; Option Acquired to Purchase Remaining Ibis Equity

... viruses and fungi, and can provide information about drug resistance, virulence and strain type of these pathogens within a few hours. Under the terms ... viruses and fungi, and can provide information about drug resistance, virulence and strain type of these pathogens. Commercial applications for the Ibis ...

CEL-SCI Corporation Releases Letter to Shareholders

... anticipate its evolution and prepare for mutant strains to appear from remote regions of the globe. Those mutant strains of the virus could possess virulence and other properties that far exceed those of the current strains. We believe the therapeutic and longer-term preventative vaccine approaches we are ...

Abbott Exercises Its Option to Acquire Ibis Biosciences, a Subsidiary of Isis

... in diagnostic procedures. It is capable of identifying virtually all bacteria, viruses and fungi, and can provide information about drug resistance, virulence and strain type of these pathogens. Commercial applications for the Ibis T5000 Biosensor System include epidemiologic surveillance, monitoring of ...

STC.UNM Signs License Option Agreement With GeneThera for E. coli O157:H7 Vaccine

... but now Chief of Environmental Microbiology in the Maryland Department of Health. These bacteria are harmless to humans and animals because the key virulence genes of the bugs are mutated by molecular approaches. According to the CDC, " ... there may be about 70,000 infections with E. coli O157 each year ...

Isis' Ibis Biosciences Subsidiary Highlights the Power of the Ibis T5000 Pathogen Identification and Characterization System at the ICAAC/IDSA Meeting

... in diagnostic procedures. It is capable of identifying virtually all bacteria, viruses and fungi, and can provide information about drug resistance, virulence and strain type of these pathogens. Commercial applications for the Ibis T5000 Biosensor System include epidemiologic surveillance, monitoring of ...

Isis Announces Award of Up to $8.4 Million in New Government Grants and Contracts to Its Ibis Biosciences Subsidiary for Pathogen Detection and Human Forensics

... in diagnostic procedures. It is capable of identifying virtually all bacteria, viruses and fungi, and can provide information about drug resistance, virulence and strain type of these pathogens. Commercial applications for the Ibis T5000 Biosensor System include epidemiologic surveillance, monitoring of ...

U.S. Genomics Inc. Receives $4.5 Million Investment from BD

... molecular diagnostic test. A diagnostic platform based on DLA has the potential to provide information to physicians concerning pathogen identity, virulence and drug resistance within hours, as opposed to the multi-day techniques such as culturing, plating, and staining that are done today. U.S. ...

Abbott Invests Additional $20M in Isis' Subsidiary Ibis Biosciences

... in diagnostic procedures. It is capable of identifying virtually all bacteria, viruses and fungi, and can provide information about drug resistance, virulence and strain type of these pathogens. Commercial applications for the Ibis T5000 Biosensor System include epidemiologic surveillance, monitoring of ...

Webcast Alert: Isis Pharmaceuticals Announces a Business Update Conference Call

... in diagnostic procedures. It is capable of identifying virtually all bacteria, viruses and fungi, and can provide information about drug resistance, virulence and strain type of these pathogens. Commercial applications for the Ibis T5000 Biosensor System include epidemiologic surveillance, monitoring of ...

Laureate Pharma Announces Manufacturing Agreement With Alopexx Pharmaceuticals, LLC

... resistance. The target of the antibody is a carbohydrate on the bacterial capsule known as PNAG. PNAG has been found to be a critical factor in the virulence and immune response to MRSA as well as non-MRSA staphylococcal infections and is also expressed by other bacterial pathogens. Alopexx ...

QuoNova Global Executive Appointments

... to communicate and recognize population density (Quorum Sensing) in order to organize their social behaviour, and co-ordinate the production of virulence factors, such as the release of toxins and biofilm formation. Biofilms are complex matrices produced by colonies of micro-organisms, and are very ...

QSB Anti-Virulence Platform Inhibits Biofilm Formation by Staphylococcus Aureus MRSA and Candida sp

... to communicate and recognize population density (Quorum Sensing) in order to organize their social behaviour, and co-ordinate the production of virulence factors, such as the release of toxins and biofilm formation. Biofilms are complex matrices produced by colonies of micro-organisms, and are very ...

Tips from the Journals of the American Society for Microbiology

... into Wyeth and MVA strains, we have developed two smallpox vaccine candidates with greater immunogenicity and efficacy yet with more-attenuated virulence than the currently licensed Dryvax vaccine suitable for contemporary populations, say the researchers. (L.P. Perera, T.A. Waldmann, J.D. Mosca, N. ...

Isis Announces $4.2 Million in Government Contracts Awarded to Its Ibis Subsidiary for Biodefense Applications Development

... agents. The Ibis T5000 is capable of identifying virtually all bacteria, viruses and fungi, and can provide information about drug resistance, virulence and strain type of these pathogens. Commercial applications for the Ibis T5000 Biosensor System include epidemiologic surveillance, monitoring of ...

Separation and Comparison of Proteins From Virulent and Nonvirulent Strains of the Fish Pathogen Flavobacterium psychrophilum, Using a 2-D Electrophoretic Approach

... likely been hampered by altered expression of virulence factors among different strains of F. ... (2-D PAGE) to identify antigens and virulence factors of this bacterium that may be targeted ... The role these play in pathogen virulence and immunoprotection is currently being evaluated ...

Microfluidic analysis of multiplex PCR products for the genotyping of Helicobacter pylori

... that certain combinations of virulence subtypes of different H. pylori sub-strains ... Briefly, genomic sub-fragments of the virulence factors vacA, cagA, and iceA were ... (mPCR) assay in order to identify the different virulence factors of Helicobacter pylori, vacA, cagA ...

Whole Genomes From Microbes to Man

... used to discover why patients experience toxic side effects, or fail to respond to medication and to identify the causes of antibiotic resistance and virulence in pathogenic organisms. Wisconsin- based OpGen, has announced the commercial launch of its Optical Mapping(TM) system for rapid, cost-effective ...

Flu institute a booster shot for Wisconsin biotech stature

... how flu viruses organize their genetic material to create infectious particles. Kawaokas lab is studying the molecular basis of the high virulence of the H5N1 avian flu virus in mammals, and how it was directly transmitted from birds to humans. His research is basically on the virus, itself, how ...

Use of the DCode System to Detect the Food-Borne Bacterial Pathogen Listeria monocytogenes

... cases the primers typically target a hypervariable region of the 16S rRNA gene (16S rDNA), or a sequence of a gene coding for a virulence factor unique to this bacterium. 4 There are instances, however, where one may wish to screen for more than one type of ...