Tumors in Biological Technology

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

... that reducing the ratio of these cells within tumors may dramatically improve anti-cancer treatment," ... the proportion of cancer stem cells found in tumors compared to chemotherapy alone. In addition, we ... of published experiments using primary human tumors in xenograft models, OncoMed scientists assessed ...

PTC Therapeutics Initiates Phase 2 Clinical Trial of PTC299 in Patients with Neurofibromatosis Type 2

... vessels. Patients with NF2 typically develop tumors that compress the auditory nerves, often leading ... problems with balance. If unchecked, NF2-related tumors may eventually damage other cranial nerves and ... Current standard treatments for NF2-related tumors include surgery and radiation therapy. However, ...

Santaris Pharma - Interim Report for the Period 1 January to 30 June 2009

... developed Hif-1alpha inhibitor targeting solid tumors at the AACR meeting in May. Enzon expects to ... its phase I clinical trials targeting solid tumors with EZN2968 in the 2nd half of 2009. Further ... initiated a phase I clinical trial in solid tumors with the LNA-based drug Survivin targeting ....

Data Presented at Society of Nuclear Medicine 2009 Annual Meeting Supports Potential of Peregrine's Cotara(R) for the Treatment of Brain Cancer

... agent Cotara(R) specifically localizes to brain tumors at high concentrations with minimal radiation ... the study, the concentration of Cotara in brain tumors was on average more than 300-fold higher than in ... the concentration of Cotara in GBM patients' tumors and in their healthy brain tissue, as well as in ...

PTC Therapeutics Receives $2.6 Million in Government Grants

... of the central nervous system, typically develop tumors that compress the auditory nerves, often leading ... problems with balance. If unchecked, NF2-related tumors may eventually damage other cranial nerves and ... Current standard treatments for NF2-related tumors include surgery and radiation therapy. VEGF ...

The World's Smallest Hero! Rexin-G, Targeted Therapy for Metastatic Cancers

... body seeking out cancerous tissues and metastatic tumors that have spread far and wide. Imagine an entire ... within the flagrant, otherwise intractable tumors with one goal in mind: to destroy the metastatic ... for the treatment of all solid chemo-resistant tumors in the Republic of the Philippines. It has ...

Proteolix to Present Carfilzomib Clinical Data During the 2009 ASCO Annual Meeting

... Multiple Myeloma and Advanced Solid tumors Featured in Oral Presentations SOUTH SAN ... in multiple myeloma and advanced solid tumors will be presented at the 2009 Annual Meeting of ... patients with selected advanced metastatic solid tumors will be presented on Saturday, May 30 during an ...

Access Pharmaceuticals Presents New Data on ProLindac(TM) at the 2009 AACR Annual Meeting

... shown to be active in a wide variety of solid tumors in both preclinical models and in human trials. ... shown to be active in a wide variety of solid tumors in both preclinical models and in human trials. ... which is activated in the hypoxic zones of solid tumors to kill cancer cells; Alchemix, a ...

Groundbreaking Research Begins for Pancreatic and Lung Cancers

... molecular basis of chemotherapy resistance. Some tumors respond very well to chemotherapy while others ... By comparing the gene expression patterns in tumors that have become resistant to chemotherapy with patterns of these same tumors prior to chemotherapy, the research team hopes to ...

InSightec Ltd. Announces US$15 Million Investment Round

... metastases, prostate cancer, breast cancer, liver tumors and brain tumors. Recent publications have shown ... pain-relieving treatment for tumors that have spread to the bones (bone metastases). ... intensity focused ultrasound to thermally ablate tumors inside the body non-invasively. MR thermometry, ...

Quest PharmaTech Announces Results Showing its Photosensitizer, SL052, is an Effective Immuno-Stimulant when combined with Immunotherapy for the Removal of Solid Tumors

... enhance its therapeutic effect on both primary tumors and metastases at distant sites. The study ... with broad potential to treat a variety of solid tumors using photodynamic (light activation) therapy or ... therapy is applicable for superficial level solid tumors and sonodynamic therapy targets more deeply ...

Safer nanoparticles spotlight tumors, deliver drugs

... is promising when it comes to illuminating tiny tumors or precisely delivering drugs, but many worry ... their safer nanoparticles in mice, they saw tumors glow for several hours, then dim as the particles ... February 22. This is the first sudy to image tumors and organs using biodegradable silicon ...

AngioGenex Presents Data on its Id Targeted Anti-Angiogenesis Inhibitors at Two Scientific Conferences

... on the control of new blood vessel formation into tumors by the Id genes and proteins confirms that drugs ... prevent the formation of new blood vessels into tumors (angiogenesis). The Company's technology is ... of new blood vessels into tumors, allowing tumors to grow and metastasize. Dr. Benezra demonstrated ...

Neurosurgery Journal Issues Supplement Dedicated to CyberKnife Radiosurgery Experience

... reported on the treatment of 199 benign cranial tumors using CyberKnife radiosurgery delivered in two to ... with single-session radiosurgery because the tumors were too large or too close to sensitive ... robotic radiosurgery system designed to treat tumors anywhere in the body non- invasively. Using ...

Oncology Biomarker KRAS to be Discussed at FDA Panel Meeting

... showed that mCRC patients with mutated KRAS tumors do not respond to Vectibix monotherapy. Conversely, patients with wild-type KRAS tumors treated with Vectibix have a better response rate ... restricting use to those patients with mCRC whose tumors have wild-type KRAS genes." To further ...

Cryoablation of Early Invasive Ductal Breast Cancer With MRI Confirmation Shows Promising Clinical Benefits, According to Study Presented at RSNA

... destroy cancerous and noncancerous tumors of the liver, prostate, kidney and breast, the gating factor for the treatment of breast cancer tumors was the ability to visualize the extent of the ... used in the cryoablation of non-cancerous tumors called fibroadenomas since its initial FDA market ...

Vicenza Hospital Becomes First European Facility to Purchase Its Second CyberKnife System

... radiosurgery have evolved beyond brain and spine tumors into extracranial applications, such as lung ... arteriovenous malformations (AVM) and benign tumors in the brain such as neuromas and meningiomas. ... CyberKnife radiosurgery has evolved to address tumors anywhere in the body, demand for the treatment ...

University of Florida and Cyntellect Collaborate to Unlock Mysteries of Cancer Stem Cells

... CSCs are cancer cells (found within tumors or hematological cancers) that possess ... non-tumorigenic cancer cells. CSCs may generate tumors through the stem cell processes of self-renewal ... cell types. Such cells are proposed to persist in tumors as a distinct population and cause relapse and ...

Data Presented at Cancer Molecular Markers Meeting Suggests Clinical Benefit for Integrating New Molecular Tests

... of metastatic tumors, and 82 percent of the tumors in studies containing a blend of primary and ... were separated into two subgroups: metastatic tumors only (n=368 specimens), and blended studies that combined primary tumors and metastases (n=298 specimens). The ...

CyberKnife System Achieves 38 Percent Growth in Extracranial Treatments During Fiscal Year 2008

... today that treatments of extracranial tumors using the CyberKnife(R) Robotic Radiosurgery ... only -- dedicated radiosurgery system to treat tumors anywhere in the body. "The CyberKnife System ... support the use of CyberKnife radiosurgery for tumors throughout the body, including the brain, spine, ...

Large-scale genetic study sheds new light on lung cancer

... researchers found more than two-thirds of the 188 tumors studied had at least one gene mutation affecting ... the TSP's finding that more than 30 percent of tumors had mutations affecting the mammalian target of ... percentage of lung adenocarcinoma patients whose tumors have mutations that activate the KDR gene. In ...

First CyberKnife System Purchased in Latin America

... ability to treat not only intracranial tumors but also extracranial tumors with extreme accuracy is unrivaled in the ... robotic radiosurgery system designed to treat tumors anywhere in the body non- invasively. Using ...

Swedish Neuroscience Institute and Institute for Systems Biology in Seattle Form Alliance to Learn More about Brain Diseases

... to a deep understanding of the kinds of brain tumors today that are inevitably fatal." ISB has been ... "One thing that's made learning about these tumors difficult is that there are few patients at any one center and the tumors progress so rapidly without treatment. With the ...

Delaware Man Spearheads Brain Tumor Awareness

... Americans will become just as familiar with brain tumors as they are with breast cancer, and to get ... and one of six accompanying facts, such as "brain tumors are the second leading cancer-related cause of ... and best friend Kelly, I'm working to make brain tumors as familiar in the future as breast cancer ...

Epeius Biotechnologies' Lead Product, Rexin-G for Metastatic Cancer, Aptly Highlighted by National Cancer Institute Journal

... and accumulating in primary tumors and metastatic tissues that have spread ... in the Philippines for the treatment of all solid tumors that are refractory to standard chemotherapies. ... own immune cells in the area of residual tumors to prevent recurrence. Remarkably, several of the ...

Brain Cancer Patients at Two Leading Hospitals Treated Using Fast and Efficient RapidArc Radiotherapy Technology from Varian Medical Systems

... radiosurgery is used to quickly eradicate tumors by targeting them with high doses of radiation ... which targets treatment beams at tumors while rotating continuously around the patient, ... treatments for head & neck, brain and prostate tumors but from September onwards RapidArc will replace ...

Gleevec Receives FDA Priority Review as First Therapy to Reduce Recurrence of Gastrointestinal Stromal Tumors After Surgery

... surgery in kit-positive gastrointestinal stromal tumors (GIST). FDA priority review status is granted to ... also has a therapy for the treatment of carcinoid tumors and acromegaly and multiple treatments in the ... About gastrointestinal stromal tumors (GIST) Gastrointestinal ...

Rosetta Genomics Reports Second Quarter 2008 Financial Results

... in differentiating between the many possible tumors in the lung and pleura. Based on a few ... differentiate mesothelioma from adenocarcinoma tumors including lung adenocarcinoma and metastases ... differentiating primary from metastatic tumors of the brain. The results have been published ...

St. Luke's Episcopal Hospital to Add CyberKnife System to Treatment Offerings

... it will give the hospital flexibility to treat tumors in the spine, lung, prostate, kidney and pancreas ... capable of delivering high doses of radiation to tumors anywhere in the body with ... The robotic arm also enables the system to target tumors that are unreachable by other radiosurgery ...

Access Licenses ProLindac(TM) to Jiangsu Aosaikang Pharmaceutical Co., LTD., a Leading Oncology Pharmaceutical Company for Manufacturing, Development and Commercialization in the Greater China Region

... shown to be active in a wide variety of solid tumors in both preclinical models and in human trials. ... shown to be active in a wide variety of solid tumors in both preclinical models and in human trials. ... which is activated in the hypoxic zones of solid tumors to kill cancer cells; Alchemix, a ...

Ipsogen Launches MapQuant Dx(TM) Genomic Grade Test to Identify Breast Cancer Patients who Benefit From Chemotherapy

... By contrast, most low-grade "grade 1" tumors should not be treated with chemotherapy because ... low-grade tumors. It can resolve these "grade 2" tumors into either "grade 1" or "grade 3" tumors in 80 % of cases. MapQuant Dx(TM) Genomic Grade ...

/C O R R E C T I O N -- Rosetta Genomics Ltd/

... in differentiating between the many possible tumors in the lung and pleura. Based on a few ... to differentiate between primary liver and brain tumors and metastases to these organs. - Women's ... molecular analysis of human brain cancer tumors to identify unique microRNA biomarkers that have ...

Rosetta Genomics Reports First Quarter 2008 Financial Results

... in differentiating between the many possible tumors in the lung and pleura. Based on a few ... to differentiate between primary liver and brain tumors and metastases to these organs. - Women's ... molecular analysis of human brain cancer tumors to identify unique microRNA biomarkers that have ...

JCI table of contents: April 22, 2008

... types of image are better than one for analyzing tumors Doctors treating individuals with cancer ... same time has been developed and used to image tumors in mice by Murali Krishna and colleagues, at the ... to determine the best treatment approach for tumors and other diseases as well as to monitor ...

Nanosized technology has supersized effect on tumors

... researchers focused a powerful drug directly on tumors in rabbits using drug-coated nanoparticles. They ... of blood vessel cells, so it inhibited tumors from expanding their blood supply and slowed ... in very low doses because they concentrate where tumors create new blood vessels. The rabbits that ...

EntreMed Announces 2008 Corporate and Clinical Program Priorities

... by the FDA and a Phase 1 study in solid tumors is expected to enroll patients in early 2Q08. ... 2008 include initiating a Phase 1 trial in solid tumors (1Q08); initiating a Phase 1 trial in hematological tumors (3Q08/4Q08); and entering into a development ...

Micromet, Inc. Reports Fourth Quarter and Full Year 2007 Financial Results

... that is highly expressed on many solid tumors and on cancer stem cells -- those cancer cells responsible for metastasis and resistance of tumors to chemotherapies. -- In 2007, Micromet ... trial of MT110 in patients with solid tumors in the first half of 2008. -- Micromet is ...

Anavex 7-1037 reduces rate of cancer tumor growth 69% in pre-clinical studies, compared to currently marketed drug Dacarbazine showing no measurable activity

... ANAVEX 7-1037 was administered beginning when tumors in advanced-stage subcutaneous mice models ... Administration of ANAVEX 7-1037 was stopped when tumors of the control group had grown to approximately ... of at least seven animals, which is equal to 14 tumors or ...

SuperGen Reports 2007 Fourth Quarter and Annual Financial Results

... and commercialization of therapies for solid tumors and hematological malignancies, today reported ... experienced patients with a variety of solid tumors irrespective of previous lines of therapy. ... and commercialization of therapies for solid tumors and hematological malignancies. SuperGen ...

Publication in Clinical Cancer Research Confirms Ability of Peregrine's Bavituximab to Target Tumor Blood Vessels with Excellent Specificity

... for Molecular Imaging of tumors - TUSTIN, Calif., March 3 ... tumor blood vessels, strongly localizing to the tumors rather than normal organs. The study was ... have utility for the non-invasive imaging of tumors in cancer patients. Although the study ...