Human Genome Sciences Reports Positive Long-Term Data for BENLYSTA(TM) (Formerly LymphoStat-B(R)) in Patients With Active Systemic Lupus Erythematosus
... (defined by an improvement in SELENA SLEDAI
score of 4 points or greater, no BILAG worsening, and ... experiencing one new BILAG A organ domain
score (which would indicate a severe flare of lupus ... or more than one new BILAG B organ domain
score (which would indicate a moderate flare of disease ...
Boston Scientific Welcomes Launch of Syntax Score Website
... Scientific Program in Barcelona.
The SYNTAX
score was developed in connection with the SYNTAX ... informed treatment decisions.
The SYNTAX
score was used in the trial to characterize coronary ... frequency, complexity and location; it assigned a
score to each patient. Higher SYNTAX Scores indicate ...
Genomic Health Announces Positive Preliminary Results from QUASAR Validation Study of Oncotype DX(R) Colon Cancer Assay
... to make the Onco type DX colon cancer Recurrence
score available to physicians and patients in early ... make the Onco type DX colon cancer Recurrence
score available to physicians and patients in early ... Health logo, Oncotype, Oncotype DX and Recurrence
score are trademarks or registered trademarks of ...
Frost & Sullivan Lauds Carl Zeiss Meditec for Dominating the OCT Market for Ophthalmic Applications
... overall Frost & Sullivan Competitive Metrics
score in the recently completed Strategic Analysis of ... segment of the Analysis."
With an overall
score of 10.22, Carl Zeiss Meditec received tier I ... 'growth strategy,' and 'leveragable assets'. The
score break-up is 2.67 for 'market positioning and ...
Physicians in Europe Rate Novartis #1 on Service Delivery, While Merck Earns Top Honors in the US
... in any other market.
"In the US, companies
score well on rep attributes -- such as knowledge, ... In the US, for example, the average TRI*M(TM)
score -- a measure of relationship strength -- fell ... their scores tumble. Though the UK's TRI*M(TM)
score overall remains fairly low, individual companies ...
Genomic Health Announces Commencement of QUASAR Clinical Validation Study for Oncotype DX(R) Colon Cancer Assay
... designed to generate both a prognostic Recurrence
score and predictive Treatment Score. Researchers will evaluate the association of the Recurrence
score with recurrence in stage II colon cancer patients ... also evaluate the association of the Treatment
score with the magnitude of chemotherapy benefit in ...
Phase 3 Data Demonstrate Efficacy and Tolerability of Paliperidone Palmitate, an Investigational Long-Acting Therapy for the Treatment of Schizophrenia
... of the trial was change in PANSS(c) total
score from baseline to endpoint.
The results ... primary endpoint was the change in PANSS total
score from baseline to endpoint. Non-inferiority was ... in the least square adjusted mean change in PANSS
score was -2.6 points, with a 95% confidence interval ...
Genomic Health Announces Publication of a Study Demonstrating the Oncotype DX(R) Breast Cancer Assay Influences Chemotherapy Treatment Recommendation in 44 Percent of Patients Evaluated
... three risk categories based on the Recurrence
score result.
Researchers compared treatment recommendations made utilizing the
Recurrence
score result to recommendations made based on the 2007 ... alone based on their Oncotype DX Recurrence
score of
less than 18. Conversely, and notably, four ...
One-Year Data Show Golimumab Improved Signs and Symptoms In Patients with Psoriatic Arthritis In Phase 3 Study
... as measured by good or
moderate Disease Activity
score 28 (DAS 28) response. At week 24, 64
percent and ... to placebo patients
worsening by a mean of 0.01
score (P < 0.001). At one year, the mean
improvements ... Maastricht Ankylosing
Spondylitis Enthesitis
score (MASES), respectively. In patients ...
FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania
... Depression Rating Scale) total
score compared to placebo
at week 8. In the study, ... than placebo. The mean change in MADRS total
score from
baseline to Week 8 was -17.4 for SEROQUEL XR ... in YMRS(**) (Young Mania Rating Scale)
total
score compared to placebo at week 3. The study showed ...
FDA Approves GlaxoSmithKline's AVODART(R) in Combination with Tamsulosin for the Treatment of Symptomatic Enlarged Prostate
... was the change in International Prostate
Symptom
score (IPSS) from baseline at Month 24 for combination ... to 125 mL and International
Prostate Symptom
score (IPSS) greater than or equal to 12] ...
* The International Prostate Symptom
score (IPSS) is a symptom index for enlarged ...
Anavex 7-1037 reduces rate of cancer tumor growth 69% in pre-clinical studies, compared to currently marketed drug Dacarbazine showing no measurable activity
... at
dosage levels of 100 mg/kg. A deltaT/deltaC
score of 31% was demonstrated,
where T is equal to the ... 7-1037 group than in the control group.
The 31%
score achieved with ANAVEX 7-1037 is far better (lower) than the
42% deltaT/deltaC
score standard set by the U.S. National Cancer ...
U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) as the First Medication for Add-On Treatment of Major Depressive Disorder (MDD)
... symptoms. A reduction in MADRS Total
score represents an
improvement in depressive symptoms. ... placebo plus ADT in reducing the mean SDS Total
score in one
study. In these studies, adjunctive ... Rating Scale (HAMD17), minimal HAMD17
score of 14, and a Clinical Global Impressions ...
SAPHRIS(R) (asenapine) Meets Primary Endpoint in Long-Term Extension Study in Patients With Predominant, Persistent Negative Symptoms of Schizophrenia
... repeated measures (MMRM), least square mean changes in the NSA-16 total
score were -15.8 for SAPHRIS vs. -11.0 for olanzapine (P=0.015). Full results ... demonstrated statistically significantly greater change in NSA-16 total
score from the core study baseline after one year of treatment, the primary ...
New Report Just Published: World Prostate Cancer Therapeutics Market Report
... Ultrasound II-26
Staging of Prostate Cancer II-26
Gleason
score II-27
Gleason
score and Grading of Prostate Cancer II-27
TNM Staging II-27
T-Staging ...
BioSyntech Reports Positive Results from Pivotal Trial for BST-CarGel(R) Cartilage Repair Device
... between treatment groups at p(less than)0.05. First, the Overall ICRS II
score was significantly better for the BST-CarGel group than for the ... important parameter within the ICRS II scoring system, the ICRS II Overall
score assimilates all the parameters listed in the grading system to generate an ...
AEterna Zentaris to Report Data from Safety Study of Phase 3 Program in Benign Prostatic Hyperplasia with Cetrorelix Ahead of Schedule
... stability of voiding symptoms based on the International Prostate Symptom
score (IPSS). Patients are then randomly allocated to cetrorelix or placebo in a ... will be followed-up for safety, International Prostate Symptom
score (IPSS) and quality of life during the extended treatment, providing ...
AEterna Zentaris Opens Extended Study for Cetrorelix in Benign Prostatic Hyperplasia
... study will be followed-up for safety, International Prostate Symptom
score (IPSS) and quality of life during the extended treatment, providing ... stability of voiding symptoms based on the International Prostate Symptom
score (IPSS). Patients are then randomly allocated to cetrorelix or placebo in a ...
Study Finds Noninvasive Blood Test for Liver Fibrosis May Alleviate Need for Liver Biopsies for Some Patients with Chronic Hepatitis C
... from a study of 214 healthy volunteers. The diagnostic performance
score for Hepascore by AUROC(1) was 0.81 for significant fibrosis, 0.83 for ... a test's overall performance based on sensitivity and specificity, with a
score up to 1.0. The closer a test scores to 1.0, the more accurate its ...
Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients
... was defined as the rate of response (defined as a decrease in CDAI
score greater than or equal to 100 points from baseline) at week 6. Remission was defined as a CDAI
score of less than or equal to 150 points. After the induction period, 62 ...
Novel Once Daily Anti-Epileptic Zebinix(R) Approved in the European Union
... health related quality of
life (HRQoL) as measured by the QOLIE-31
score during a one year open label
extension of the above 3 studies. ESL is ... a statistically significant improvement from baseline in the
overall MADRS
score (p<0.0001) and individual domains of the MADRS scale
including ...
Traditional Risk Factors Often Miss Heart Disease Warning Signs
... a series of clinical studies showing that the traditional Framingham risk
score doesn't always do a good job of estimating that risk, especially among ... III guidelines.
The authors concluded that, "The Framingham risk
score underestimates cardiovascular risk in individuals with a family history of ...
Sangamo BioSciences Announces Results From Diabetic Neuropathy Clinical Trial SB-509-601
... analog scale for pain intensity
(VASPI), a modified Neuropathy Impairment
score -- Lower Limbs (NIS-LL)
scoring system as well as total neuropathy
score (TNS) to assess signs and
symptoms of the condition. In addition, data ...
Global Study Shows That Majority of Women with Osteoporosis Do Not Consider Themselves at Higher Risk for Fractures
... self-care, usual activities of daily living, pain, and
depression. The
score is expressed as a health utility score, 1
representing perfect health and ... 45 years (0.78 vs.
0.74 and 0.65, respectively). The mean health utility
score ranged from
0.76 for women with wrist fractures to 0.64 for women with ...
Sanofi Aventis : New Study Results Support the "Basal Plus" Strategy With LANTUS(R) and APIDRA(R) to Improve Blood Sugar Control in Patients With Type 2 Diabetes
... In the Telecare arm of the study, 50.6%
of patients reached an A1C
score of less than or equal to 7%, whereas in
the standard blood glucose monitoring arm, 54.6% of patients similarly
achieved an A1C
score of less than or equal to 7%.
About the ELEONOR Study
ELEONOR was an ...
Landmark SYNTAX Trial Reports Comparable Safety Outcomes for Complex Patients Treated With TAXUS(R) Express2(TM) Stents or Bypass Surgery
... defining a new measure
for anatomical complexity - the SYNTAX
score - which seeks to provide
guidance to physicians on optimal treatment options for this high-risk
group of patients. The SYNTAX
score characterizes vasculature based on
lesion frequency, complexity and ...
Video: Higher Initial Dose of Gleevec Achieved Better Early Responses than Standard Dose for Patients with Chronic Myeloid Leukemia
... standard 400 mg/day dose in a 2:1 ratio. Patients were
stratified by Sokal
score for evaluation. Sokal
score is a clinical measure
that is used to identify those at highest risk for ...
Phase 3 studies show golimumab significantly improved signs and symptoms of rheumatoid arthritis
... with some patients achieving remission as measured by Disease Activity
score (DAS28). Findings from two multicenter, randomized, double-blind, ... clinically relevant improvement in physical function (improvement in HAQ
score of at least 0.25 from baseline), compared with 39 percent of patients ...
Genomic Health Announces Expansion of Oncotype DX(R) Breast Cancer Test to Include Quantitative Estrogen Receptor (ER) and Progesterone Receptor (PR) Scores
... or a semi-quantitative result, RT-PCR by Oncotype DX
generates a specific
score across a continuous range of expression which
allows physicians to factor ... Health, the Genomic Health logo, Oncotype, Oncotype DX
and Recurrence
score are trademarks or registered trademarks of Genomic
Health, Inc. All other ...
Vermillion Biomarker Panel Potential Aid in the Diagnosis of Peripheral Artery Disease
... combinations of protein markers to create a
distinct biomarker panel
score to stratify individuals according to their
risk of having PAD. However, ... Drug Administration (FDA)."
The study was conducted to develop an index
score based on a
combination of proposed biomarkers for PAD, including two based ...
JADO Reports Clinical Proof of Concept With Raft Modulator in Atopic Dermatitis
... through a highly significant improvement in TIS (Three
Item Severity)
score after three week treatment. Both TF002 and
hydrocortisone achieved an improvement of the TIS
score of more than 1.5
which was defined as being clinical efficacious. This ...
Significant Progress Made in Nation's Preparedness to Respond to Public Health Emergencies; But Gaps in Critical Areas Threaten Overall Readiness
... they did not
achieve, therefore zero is the lowest possible overall
score and 10 the
highest. Data for the public health indicators were collected ... funding for
public health programs for FY 2005-06 to FY 2006-07?
State
score Summary
10 out of 10: Illinois, Kentucky, Nebraska, New Jersey, ...
Recent Study Confirms Alimentary Health's Bifantis(R) Demonstrates Efficacy in the Treatment of Irritable Bowel Syndrome
... infantis 35624
resulted in significant improvement in the composite
score abdominal
pain/discomfort, bloating/distention and bowel movement ... incomplete evacuation,
straining, passage of gas and a composite
score of abdominal
pain/discomfort, bloating/distention, and bowel movement ...
Genomic Health Announces Second Quarter 2009 Financial Results and Business Progress
... disclaims any obligation to update these forward-looking statements.
NOTE: The Genomic Health logo, Oncotype, Oncotype DX and Recurrence
score are trademarks or registered trademarks of Genomic Health, Inc. All other trademarks and service marks are the property of their respective owners. ...
Evidence for a New Genetic Link to Therapeutic Efficacy for Alzheimer's Disease
... scores than those previously reported were observed at each assessment time point (Day 45, 90 and 104). At Day 45 the improvement in ADAS-cog
score was 4.18 (p=0.0004), while at Day 90 the difference was 4.73 (p=0.001). Of interest, a significant difference in cognitive test scores of 3.27 was ...
Brazil's Scientific Research On The Rise, Thomson Reuters Study Finds
... below the overall world average for scientific impact, Brazil has been steadily rising towards parity since the late 1980s. It has moved from a
score that was at 44 percent of the world average during the 1985-1989 time period to 63 percent of the world mark during 2004-2008. In recent years, ...
Study Showed VYVANSE(R) (lisdexamfetamine dimesylate) CII Provided Significant Efficacy at 14 Hours After Administration in Adults with ADHD in an Adult Simulated Workplace Environment
... to placebo. The key secondary efficacy measure was to assess the duration of efficacy of VYVANSE compared to placebo using PERMP; the PERMP total
score is the sum of the number of math problems attempted (PERMP-A) plus the number of math problems answered correctly (PERMP-C) in a 10-minute session. ...
Pixantrone Significantly Increases Complete Remissions, Overall Response Rates, Frequency of Durable Remissions and Progression Free Survival in Patients with Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma
... chemotherapy treatments. More than 70% of the patients on both arms were considered intermediate to high risk by the International Prognostic Index
score (>=2). The median prior doxorubicin equivalent dose was approximately 300 mg/m2, the dose that is associated with six cycles of CHOP ...
ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week
... phase of the study is the attainment of a clinical response defined as a decrease from baseline in the Crohn's Disease Activity Index (CDAI)
score of at least 70 points.
About ChemoCentryx
ChemoCentryx, Inc., is a clinical-stage biopharmaceutical company focused on discovering, ...
Ocera Therapeutics Presents Data on AST-120 in Patients With Hepatic Encephalopathy at the European Association for the Study of Liver Disease Annual Meeting
... 150 patients with MHE. Patients will be evaluated on neurocognitive improvement at the end of the study, defined as the change in the global summary
score of the RBANS or Repeatable Battery for the Assessment of Neuropsychological Status.
"The ASTUTE trial will use a battery of neuropsychometric ...