regulator

Fluorescence-Based Single-Tube Assays to Rapidly Detect Human Gene Mutations

...on in the cystic fibrosis transmembraneconductance regulator (CFTR) gene, and the other two are single nucleoti...10 of thecystic fibrosis transmembrane conductance regulator (CFTR) gene, accounts forapproximately 70% of all mutant CF alleles. 3,4 The Factor II(G20210A) Mx4...

Assessing Gene Function with siRNA Libraries

...ol. Cyclin B1 is a well-studied cell cycle regulator known to play a key role in initiating mitosis, and therefore was expected to yield a clear decrease in mitotic index in this study. The <A href="http://www.ambion.com/catalog/CatNum.php?4611"> Silencer ...

Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System

...mportant to set the helium pressure at the regulator valve 200 psi over the pressure rating of the rupture disk being used, and to adjust the helium metering valve so that the helium flow rate into the gas acceleration tube occurs at a rate such that a 1,550 psi rupture disk wil...

Single-Cell Complementation of Barley Mlo Mutants Using a PDS-1000/He Hepta System

...brane and is presumed to act as a negative regulator of a basal defense mechanism (Devoto et al. 1999). We have previously shown that transient single-cell expression of wild-type Mlo in Mlo resistant leaves restores susceptibility to Blumeria graminis (Shirasu et al. 199...

The development of a serotonin 5-HT2C receptor-binding assay using the LEADseeker Multimodality Imaging System

...ammals, serotonin (5-hydroxytryptamine, 5-HT) is a regulator of neural transmission which induces its biological effect by binding to serotonin receptors. <P >The serotonin 5-HT 2C receptor is a subtype of the serotonin receptor that belongs to the rhodopsin-like seven transmembrane superfamily of G ...

Barriers will not stop convergence of medical technologies

...ic confluence of the glucose load with the glucose regulator insulin means that for a non-diabetic person, glucose control is much more precisely controlled. This is not just a physiological mechanism but a result of very specific anatomic relationships. In the case of a diabetic patient whose subcutaneously...

On track with the FDA -- But what about your coverage and reimbursement strategy?

...iveness. By contrast, CMS is both a purchaser and regulator of medical products. In many situations, data that is sufficient for the FDA to conclude that a new product's benefits outweigh its risk for purposes of product approval is not sufficient for CMS to authorize payment. CMS authorizes payment through a...

The new techie dilemma MBA or JD?

...ntal affairs department or one local legislator or regulator that has an impact on how your company does business. Not that big a company? Doesn't really matter. The field of play isn't restricted to just your business anymore. It's the whole environment in which we conduct business and culture. The days whe...

Third Wave boosts numbers in latest report

...ditions cystic fibrosis transmembrane conductance regulator (CFTR), hepatitis C virus (HCV) and human papillomavirus (HPV), among others. "We met those milestones," Puisis said during a company conference call on Wednesday. "The combination of our commitment to building strong relationships and releasing supe...

AT&T Challenges SBC in Wisconsin With Local, Long-Distance Bundling

...le for Midwest long-distance relief forges on with regulator and watchdog adversity. Like with its other states, AT&Ts residential entrance in Wisconsin is made possible by renting parts of SBCs Wisconsin network. Known by the "UNE" moniker, Crull says UNE rates in Wisconsin havent yet been finalized, adding...