Protein in Biological Technology

Repligen Reports First Quarter Fiscal Year 2010 Financial Results

... quarter fiscal year 2010 revenue was comprised of protein A product revenue of $2,473,000 and royalty and ... HDAC inhibitors increase production of the protein frataxin which may have the potential to arrest ... are the world's leading supplier of recombinant protein A, the sales of which partially fund the ...

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

... of platelet-derived growth factor-B (PDGF-B) protein as a treatment for patients with non-healing ... a temperature of about 4 degrees Celsius. PDGF-B protein is a well known bone growth mediator and is ... is designed to provide a therapeutic level of protein synthesis at a specific site in the body and can ...

Debiopharm and MSM Protein Technologies Sign Agreement for Research and Development of Debio 0929, a Novel Oncology Biologic

... drugs that target unmet medical needs, and MSM protein Technologies (MSM), a human antibody drug ... http://www.debiopharm.com . About MSM protein Technologies MSM is a closely held drug ... Receptors (GPCRs) GPCRs comprise a large protein family of transmembrane receptors that sense ...

Sangamo BioSciences Reports Second Quarter 2009 Financial Results

... Corporation, enabling technology agreements in protein production and research grants. The revenue ... Sangamo's proprietary zinc finger DNA-binding protein nuclease (ZFN) technology. Genentech is using ZFN ... with novel characteristics for pharmaceutical protein production purposes. The milestone achievement ...

Laureate Pharma Appoints Daniel E. Leone as Vice President of Business Development

... a full-service biopharmaceutical development and protein production company, today announced the ... a full-service biopharmaceutical development and protein production company located in Princeton, New ... industry: monoclonal antibodies and recombinant protein products. For more information, contact us at ...

Novavax Announces Selection of a Respiratory Syncytial Virus Vaccine Candidate for Advanced Preclinical Studies

... This new candidate is directed against a protein on the surface of the virus, the "F" or "fusion" protein, which is the protein that the virus uses to infect and fuse with cells ... containing the F protein. The structure of the F protein in these particles is identical to the ...

Muscular protein bond -- strongest yet found in nature

... cluster" called the Center for Integrated protein Science and Prof. Matthias Wilmanns of the ... of mechanical stability in the titin-telethonin protein complex show it to be a highly "directed" bond, ... the titin-telethonin complex is the strongest protein bond found so far in nature. When force was ...

Champions Biotechnology Partners with Do-Coop Technologies to Advance Its Novel Oncology Compound Into Biomerk Tumorgraft(TM) Testing

... models to target microtubule associated protein tau (MAPT) deficient tumors with promising ... inhibitors target MAPT (Microtubule-Associated protein Tau) deficient tumors. In both in vitro and in ... Biotech companies can benefit from enhanced protein stability, cell growth clonability and secretion, ...

Inspiration Biopharmaceuticals Presents Safety Data on IB1001, a Novel Recombinant Factor IX for the Treatment of Hemophilia at the International Society on Thrombosis and Haemostasis (ISTH) Annual Meeting

... the progress that we have made in advancing our protein manufacturing technology have facilitated the ... with Inspiration's proprietary recombinant protein manufacturing technology, which significantly ... disorder caused by low levels or absence of a protein called a clotting factor, essential for blood ...

Novel drug discovery tool could identify promising new therapies for Parkinson's disease

... can rescue yeast cells from toxic levels of a protein implicated in Parkinson's disease by stimulating ... in patients with Parkinson's disease accumulate a protein called alpha-synuclein. Moreover, genetic ... toxicity. Cyclic peptides are fragments of protein that connect end-to-end to form a circle. ...

DuPont and Arzeda Collaborate to Develop Improved Crops to Increase Productivity

... to work with Arzeda, the industry leader in protein engineering and designing enzymes with novel ... Arzeda will use its proprietary computational protein design technology to custom-design novel enzymes ... in the field of computational and experimental protein engineering. Pioneer Hi-Bred, a DuPont ...

2009: Immunotec announces important clinical research initiative: New study to be launched with the goal of improving the quality of the aging process

... Study on the Effect of the Cysteine-Rich Whey protein Isolate (Immunocal(R)) in Combination with ... to determine whether taking a cysteine-rich whey protein isolate (IMMUNOCAL(R)) compared to casein (a milk protein used as control, which contains little cysteine) ...

Bioinformatics Expert Dr. Jiaan Yang Joins Sundia MediTech With Innovative PFSC Technology

... announced today that Sundia has acquired protein Folding Shape Code (PFSC) technology for doing ... and to develop an innovative method to describe protein complex 3D structure, and achieved PFSC, an ... For a long time, it has been a great challenge to protein chemists and biologists how to obtain a complete ...

Morphotek(R), Inc. Announces a Research Collaboration Agreement with Synageva BioPharma Corporation to Develop Potential Treatments for Cancer and Infectious Disease

... an integrated platform of proprietary systems for protein production, processing and purification. ... company specializing in the development of protein and antibody products through the use of novel ... in the areas of antibody therapeutics, protein therapeutics, product manufacturing, drug target ...

PROLOR Biotech Awarded Two U.S. Patents for Its Longer-Acting Human Growth Hormone and Longer-Acting Erythropoietin

... protein, CTP extends the time that the protein is active in the body. "These two new ... and the effectiveness of PROLOR's long-acting protein programs, which are made pursuant to the safe ... commercial products based upon its long-acting protein technology, including any long-acting versions of ...

Caliper Life Sciences Introduces Staccato Protein Workstation for Automated Protein Sample Preparation & Analysis

... Bottlenecks in Quality by Design Initiative for protein Therapeutics - HOPKINTON, Mass., June 29 ... sciences research, today launched the Staccato protein Workstation to specifically address bottlenecks ... as creating mechanisms for approval of follow-on protein products (biosimilars), the FDA has encouraged ...

KBI Biopharma Starts Cell Line Generation Process under Vendor Network Agreement for PER.C6(R)

... NC, applies cell line generation, extensive protein characterization, manufacturing process ... expert and integrated biophysical and biochemical protein characterization, formulation and process development and cGMP manufacturing of recombinant protein Active Pharmaceutical Ingredients (API's). For ...

Sigma-Aldrich and Atlas Antibodies Announce 2,300 New, Highly Validated Prestige Antibodies(RM)

... Additions to the Human protein Atlas, available exclusively through ... by the publicly available data of the Human protein Atlas (HPA), part of HUPO's Human Antibody ... (WB) data, all publicly accessible via the Human protein Atlas ( www.proteinatlas.org ). In August ...

CEM Wins Presidential Green Chemistry Challenge Award for the Sprint Rapid Protein Analyzer

... Conditions category for its Sprint(TM) Rapid protein Analyzer . The company will accept the award ... for generations to come." The Sprint Rapid protein Analyzer is a revolutionary technology that ... of hazardous chemicals, as the primary method for protein determination. Sprint uses CEM's iTAG(TM) ...

Rules-Based Medicine, Inc. Launches DiscoveryMAP(TM) Service for Drug and Diagnostic Development

... offering increases the odds of identifying new protein biomarker patterns in almost any drug development ... to give the most accurate and reproducible protein measurements. Multiplexing allows all of these ... Rules-Based Medicine (RBM) provides comprehensive protein biomarker products and services centered on its ...

Commercial Manufacturing of H1N1 'Swine Flu' Vaccine Underway

... week MERIDEN, Conn., June 15 /PRNewswire/ -- protein Sciences Corporation (PSC) announced that today ... also announced that it will begin shipping H1N1 protein for research use to customers with pre-orders. ... that are manufactured, using its patented protein expression technology, based upon baculovirus and ...

PTC Therapeutics Receives $2.6 Million in Government Grants

... or disease-related, production of the protein vascular endothelial growth factor (VEGF) in ... new drug that inhibits the production of the protein vascular endothelial growth factor, or VEGF, in ... to terminate translation before a full-length protein is generated. This causes ...

'Designer molecules' being developed to fight disease

... of Leicester are developing a new way to make protein based drugs with potential applications in ... functions in the human body. Over time each protein has evolved to optimise its function. Disease ... but complex set of function in the body and protein therapeutic drugs can perform better when ...

Repligen Reports Fourth Quarter and Fiscal Year 2009 Financial Results

... 52%. Total revenue for the year was comprised of protein A product revenue, and royalty and other revenue. ... Business Repligen has supplied recombinant protein A products, a consumable used in the manufacture ... are the world's leading supplier of recombinant protein A, the sales of which partially fund the ...

DNA2.0 Awarded US Patents for Breakthrough Gene Optimization Technology -- Company's Unique Algorithm Enables Expression Yields up to 50 Times Greater than Competing Approaches

... with this patent has been proven to increase protein expression yields by up to 50 times greater than ... -- DNA2.0 , the leading gene synthesis and protein engineering company, today announced that the ... genes to reliably increase levels of recombinant protein expression. DNA2.0's unique optimization ...

Sigma-Aldrich Introduces New Services Network Complementing Its Life Sciences Product Portfolio

... including cloning, mass spectrometry based protein characterization, protein expression and protein purification services to supplement their ...

Scripps Research Institute Highlights Groundbreaking Work of aTyr Pharma Scientific Co-Founder

... research with an essential enzyme of protein synthesis, tyrosyl tRNA synthetase. Synthetases are fundamental components of protein synthesis machinery in all organisms, but human ... do not disturb the activity required for protein synthesis, Professor Yang's research demonstrates ...

First ASMS Hites Award for Outstanding Research Publication Presented to Prof. Alison Ashcroft for Her Use of Waters Synapt HDMS System to Explore Protein Complexes

... Copopulated Conformational States During protein Folding Events Using Electrospray Ionization-Ion ... SYNAPT(TM) HDMS System to study the function of protein molecules and their assembly into macromolecular ... our research. We can now quantify the amount of protein that is in its native state and the amount that ...

OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer

... to inhibit the production of clusterin, a protein that is associated with cancer treatment ... reductions in pain, and a decline in PSA, a protein that is often elevated in patients with prostate ... designed to inhibit the production of a specific protein associated with treatment resistance; OGX-427 is ...

Caprion Proteomics Inc. and Applied Bioystems Work Together to Accelerate Protein Biomarker Verification and Validation

... to accelerate the verification and validation of protein biomarker candidates toward potential use in ... no available commercial assays for a given set of protein biomarker candidates, the MRM technique offers a ... and specific post translational modifications or protein isoforms are critical to monitor but difficult to ...

AFFiRiS AG: Atherosclerosis Vaccine Development Receives EU Support

... AFFITOME(R) platform technology. The target is a protein known as CETP (cholesteryl ester transfer ... vaccination against cholesteryl ester transfer protein (CETP). By transferring cholesteryl ester from HDLc to LDLc and VLDLc, this protein reduces "good" HDL and has a detrimental impact ...

ForteBio Launches New Assay Capabilities for High-Sensitivity Protein Quantitation and Fragment Screening on Its Octet(R) Platform

... two new assay modules - for high-sensitivity protein quantitation and fragment screening, respectively ... mL levels of analytes in quantitation mode. "For protein quantitation, life science researchers have ... assays can be run by biotinylating the protein of interest using streptavidin biosensors. ...

Structure of enzyme against chemical warfare agents determined

... one of only three sources worldwide equipped for protein crystallography. In contrast to structure ... yield complementary information about a protein structure. This information about hydrogen atoms ... times. Though the first neutron structure of a protein was reported 40 years ago, in 1969, to date only ...

MIT reels in RNA surprise with microbial ocean catch

... chemicals or pressure and modify their protein expression accordingly. But that sensitivity ... the observer causes the microbes to change their protein expression. That same sensitivity makes some of ... in seawater before the microbes change their protein expression, the research team collaboratively ...

OncoGenex Pharmaceuticals Announces Release of Two ASCO Abstracts: Impact of OGX-011 on Survival in Randomized Phase 2 Trial and Phase 1 Safety Data for OGX-427

... to inhibit the production of clusterin, a protein that is associated with cancer treatment ... reductions in pain, and a decline in PSA, a protein that is often elevated in patients with prostate ... is designed to reduce production of Hsp27, a protein that is over-produced in response to many cancer ...

Transgenomic and Power3 Medical Introduce NuroPro(R) Tests for Alzheimer's and Parkinson's Diseases at AAN Annual Meeting

... developed by Power3, are a panel of blood serum protein biomarkers evaluated by biostatistical analysis ... blood serum concentrations of some of the key protein biomarkers utilized in the NuroPro PD assay with ... detection and prognosis of disease, identify protein biomarkers, and drug targets, and its diagnostic ...

Recombinant C-Reactive Protein

... announced that it will increase its C-Reactive protein product line to include recombinant C-Reactive Protein. C-Reactive protein is a protein found in the blood that operates as a marker for ...

Protein Sciences Announces Signing of a Forbearance Agreement With Emergent BioSolutions

... MERIDEN, Conn., April 30 /PRNewswire/ -- protein Sciences Corporation ("PSC"), a privately owned ... Daniel D. Adams , President and CEO of protein Sciences said, "We are pleased to have an ... that are manufactured, using its patented protein expression technology, based upon baculovirus and ...

OncoGenex Receives Confirmation from FDA on the Design of a Second Phase 3 Trial Evaluating OGX-011 for the Treatment of Advanced Prostate Cancer

... to inhibit the production of clusterin, a protein that is associated with cancer treatment ... reductions in pain, and a decline in PSA, a protein that is often elevated in patients with prostate ... target and inhibit production of clusterin protein in tumor cells. OncoGenex and Isis partnered in ...

United States Recognizes Leading Scottish Scientist for Disease Research

... non-U.S. scientists. As Director of the MRC protein Phosphorylation Unit and the Scottish Institute ... In particular, he has studied abnormal protein phosphorylation as a cause or consequence of ... and cancer drugs in development. For instance, protein kinase inhibitors have been approved for clinical ...