Peptide in Biological Technology

Palatin Technologies, Inc. Receives U.S. Patent Allowance for Heart Failure Drug Candidate

... Number 11/694,260, titled "Cyclic Natriuretic peptide Constructs." Allowed claims cover a family of cyclic compounds that bind to natriuretic peptide receptor A (NPRA), including PL-3994, Palatin's ... "PL-3994 and related compounds are first-in-class peptide mimetics with extended half-lives and favorable ...

DOR BioPharma Announces Issuance of European Patent for its LPM(TM) Oral Drug Delivery Technology

... biotechnology products derived from synthetic peptide chemistry or recombinant DNA," said Christopher ... clinical development of an oral form of the peptide hormone drug leuprolide using the LPM(TM) technology. Leuprolide is a synthetic peptide agonist of gonadotropin releasing hormone (GnRh) ...

METTLER TOLEDO Introduces an Affordable Reaction Block for Solid Phase Peptide Synthesis (SPPS)

... an affordable reaction block for solid phase peptide synthesis and purification of peptide libraries: MiniBlock. For a limited time, you can register to win a MiniBlock® for Solid Phase peptide Synthesis (SPPS). ...

Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data

... ) last week analyzed the most recent peptide genomic sequence data available and determined ... ) last week analyzed the most recent peptide genomic sequence data available and determined ... testing. It used the same approach to produce a peptide H5N1 (avian flu) vaccine that successfully ...

First H1N1 Swine Flu Vaccine, Replikins-Based, Is Ready Now for Testing Worldwide

... LONDON, May 4 /PRNewswire/ -- A synthetic peptide H1N1 vaccine is available now for testing ... developed the vaccine based on the same Replikins peptide technology which provided the surprise advance ... the company also takes full advantage of modern peptide synthesis techniques to allow rapid production of ...

Pulmo BioTech Inc. Announces Paper to be Presented at Symposium

... a paper at the 5th International Symposium on peptide Receptors and Kinin 2009 to be held in Quebec, ... Circulation", will be part of the session "From a peptide to a Drug: Rational Drug Design". This ... paper on our Molecular Imaging technology at the peptide Receptors International Symposium. As a company, ...

CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies

... The L.E.A.P.S. technology combines a small peptide that activates the immune system with a small peptide from a disease-related protein, such as a herpes ... to two different and known highly conserved peptide protective epitopes from two different essential ...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

... The L.E.A.P.S. technology combines a small peptide that activates the immune system with a small peptide from a disease-related protein, such as a herpes ... CEL-2000, a L.E.A.P.S. vaccine incorporating a peptide from a rheumatoid arthritis disease protein, was ...

Psylin Neurosciences Commences Development of Compound for Depression

... ) PSN0041, a peptide from Amylin's proprietary polypeptide hormone ... but also in preclinical tests of anxiety. The peptide has several anticipated advantages over current ... Psylin's mission is to pioneer the development of peptide therapeutics for the treatment of psychiatric ...

Global Biopharmaceutical Leader in Peptide Research Expands Commitment in San Diego/U.S. With New R&D Facility and Ready-To-Market Prostate Cancer Treatment Degarelix

... that will be dedicated to further development of peptide research and therapeutics. (Photo: ... prostate cancer. Degarelix is the first peptide new chemical entity (NCE) discovered by Ferring ... on natural, hypothalamus and pituitary-based peptide hormones. Headquartered in Switzerland, ...

BioMS Medical reports results of exploratory phase II trial of dirucotide in relapsing remitting multiple sclerosis

... ---------------- Dirucotide is a synthetic peptide that consists of 17 amino acids having a sequence ... immune attack as a result of high doses of peptide periodically delivered intravenously. The ... therefore expected to be related to the role this peptide plays in that patient's immune system and disease ...

Sigma-Aldrich Signs Agreement With CPC Scientific for the Distribution of PEPscreen(R) Custom Peptide Libraries

... a leading provider of high quality custom peptide synthesis, GMP peptides and peptide APIs for the pharmaceutical and biotechnology ... will offer Sigma-Aldrich's PEPscreen(R) custom peptide libraries ( http://www.sigma.com/pepscreen ) to ...

Novel Diabetes Drug Discovery Has Potential to Reverse Disease

... a 14- amino acid human peptide, Human proIslet peptide (HIP), consisting of the bioactive region in the ... stabilized and characterized this unique peptide in a variety of preclinical studies. In these ... pre- diabetes. About HIP Human proIslet peptide (HIP) is a 14-amino acid, stabilized ...

Nile Therapeutics Announces Focus on CD-NP for Acute Heart Failure and Termination of 2NTX-99 Program

... resources on the development of its natriuretic peptide franchise, including CD-NP which is in Phase II ... to focus our resources on our core natriuretic peptide program, which is showing great promise as a ... CD-NP CD-NP is a novel chimeric natriuretic peptide in clinical development for the treatment of ...

Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist

... Zealand Pharma has applied its knowledge of peptide optimization and its proprietary SIP(r) ... Zealand Pharma's ability to bring innovative peptide projects from idea to clinical development and ... Zealand Pharma is one of the leaders within the peptide area, a growing market with significant ...

Palatin Technologies to Report Fiscal Year 2009 First Quarter Results; Conference Call and Webcast on November 17, 2008

... company dedicated to the development of peptide, peptide mimetic and small molecule compounds with a focus on melanocortin and natriuretic peptide receptor systems. The melanocortin system is ... inflammation-related diseases. The natriuretic peptide receptor system has numerous cardiovascular ...

New England Peptide Forms Scientific Advisory Board

... peptide manufacturer appoints globally renowned ... to formalize NEP's network of thought leaders in peptide chemistry. The group will assist in formulating ... gain access to a network of the world's leading peptide chemists." Vincent Bille, Ph.D. Bille ...

Palatin Technologies, Inc. Revised Call-In Number for Teleconference and Webcast to be held on September 30, 2008

... to the development of proprietary peptide, peptide mimetic and small molecule compounds with a focus on melanocortin and natriuretic peptide receptor systems. The melanocortin system is ... inflammation-related diseases. The natriuretic peptide receptor system has numerous cardiovascular ...

New England Peptide Names Director of Chemical Development

... and biophysical and biological evaluation of peptide and nucleic acid analogs, and the development of ... dyes for bioconjugation. In 2006, his work on peptide analogues for inhibiting amyloid protein ... in 1984 for the invention of solid phase peptide synthesis. "Bob brings tremendous ...

Peptimmune Presentation at Upcoming World Congress on Treatment and Research in Multiple Sclerosis

... First-in-Man Single Ascending Dose Study of peptide Copolymer PI-2301 for the Treatment of Multiple ... in early 2009. PI-2301 is a second-generation peptide copolymer from a similar compound class as ... focused on the development of peptide therapies to improve the management of chronic ...

BioMS Medical's lead drug, dirucotide (MBP8298) for the treatment of multiple sclerosis, receives fast track designation from FDA

... Dirucotide (MBP8298) is a synthetic peptide that consists of 17 amino acids having a sequence ... immune attack as a result of high doses of peptide periodically delivered intravenously. ... therefore expected to be related to the role this peptide plays in that patient's immune system. The degree ...

Palatin Technologies, Inc. Reports Positive Results of Phase 2a Clinical Study with PL-3994 for the Treatment of Heart Failure

... of PL-3994, a novel, long-acting natriuretic peptide receptor A (NPRA) agonist under development for ... to the development of proprietary peptide, peptide mimetic and small molecule agonist compounds with ... inflammation-related diseases. The natriuretic peptide receptor system has numerous cardiovascular ...

BioMS Medical announces positive interim analysis on phase III trial of dirucotide (MBP8298) for multiple sclerosis

... Dirucotide (MBP8298) is a synthetic peptide that consists of 17 amino acids having a sequence ... immune attack as a result of high doses of peptide periodically delivered intravenously. ... therefore expected to be related to the role this peptide plays in that patient's immune system. The degree ...

New England Peptide Implements Quality Management System, Prepares for ISO 9001: 2008 Registration

... by incorporating data harnessed though each peptide production run with decades worth of proven peptide chemistry knowledge and trends. New standard ... are fueling a surge in use. All segments of the peptide market - from therapeutics and vaccines to ...

Chromatide and Novasep Have Extended Their Partnership to Develop Large Scale Solid Phase Peptide and Oligonucleotide Synthesis Technology.

... partnership to develop large scale solid phase peptide and oligonucleotide synthesis technology. The ... experience in solid phase synthesis of peptide and oligonucleotides, including the production of ... "The Chromatide team has many years experience in peptide and oligonucleotide synthesis and has excellent ...

Self-assembled materials form mini stem cell lab

... even more exciting. One of the molecules is a peptide amphiphile (PA), small synthetic molecules that ... interesting about the interaction between peptide amphiphiles and biopolymers from our previous ... of the flat membrane, the researchers put the peptide amphiphile solution at the bottom of a shallow ...

MannKind Corporation Response to Recent Market Events

... associated with the ability to deliver a peptide hormone in ways that mimic normal ... efficacy and safety advantages in the delivery of peptide hormones. MannKind is committed to continuing the ... of Technosphere(R) Insulin and MKC253. A third peptide hormone for the treatment of obesity is in ...

MUSC Spin-Off Company to Test Regenerative Wound Healing Gel

... trial process for its unique, wound-healing peptide gel. Already past the preliminary approval ... Digestive Kidney Diseases grant to study the peptide in treating diabetic wounds. The two entities are ... helps regulate communication between cells. This peptide accelerated wound healing and tissue regeneration ...

Peptimmune Announces First Close of Series D Private Financing

... About PI-2301 PI-2301 is a second generation peptide copolymer from a similar compound class as ... been optimized using Peptimmune's novel platform peptide chemistry and in pre-clinical studies, has shown ... focused on the development of peptide therapies to improve the management of chronic ...

Lilly and BioMS Medical Announce Global Licensing and Development Agreement

... About MBP8298 MBP8298 is a synthetic peptide that consists of 17 amino acids having a sequence ... immune attack as a result of high doses of peptide delivered periodically by the intravenous route. ... therefore expected to be related to the role this peptide plays in that patient's immune system. The degree ...

Xenome Receives a Syndicated US$10 Million Equity Investment from Queensland BioCapital Fund, Amylin Pharmaceuticals and Innovis Investment Partners

... company developing novel peptide drugs, announced today that it has successfully ... of new compounds from Xenome's unique peptide library using Amylin's assay technologies in the ... provides a tremendous validation of the Company's peptide drug discovery platform and will facilitate ...

New drugs faster from natural compounds: A UC San Diego breakthrough

... identified this fact. These algorithms make sense of the flood of tiny peptide fragments that are generated by machines called mass spectrometers that ... the authors present new algorithms that computers use to piece these peptide fragments back together in order to determine the chemical structure of a ...

Calvert Research Licenses Novel Technology to Treat Age Related Macular Degeneration from Tulane University

... were developed in the laboratory of Dr. David H. Coy and his team at the peptide Research Laboratory at Tulane University. AMD is a leading ... Calvert T1 combine the known anti-proliferative effects of a somatostatin peptide analog with a cytotoxic drug chemically linked to the peptide, resulting ...

CEL-SCI Developing Immune-Based Treatment Against Swine and Other H1N1 Flu Viruses Using Proprietary L.E.A.P.S. Technology

... from the L.E.A.P.S. technology, showed adjuvant activity when used with a peptide based malaria vaccine and a DNA based malaria vaccine in animal challenge ... linked to an Immune/T-cell binding ligand (I/TCBL) can be manufactured by peptide synthesis or by covalently linking the two peptides. Depending upon the ...

Nile Therapeutics CD-NP Clinical Program for Acute Heart Failure Released From Clinical Hold by FDA

... end of 2009. About CD-NP CD-NP is a novel chimeric natriuretic peptide in clinical development for the treatment of acute heart failure. CD-NP ... developing its lead compound, CD-NP, a novel rationally designed chimeric peptide in clinical studies for the treatment of heart failure, and CU-NP, a ...

H1N1 Influenza "Swine Flu" Peptide Vaccine Now Available For Testing Worldwide

... The company has developed the vaccine based on the same Replikins peptide technology which provided the surprise advance warning one year ago that ... The company has developed the vaccine based on the same Replikins peptide technology which provided the surprise advance warning one year ago that ...

Kun Run Biotechnology, Inc. Year-End Revenues Increase 56% to $11.6 million

... portfolio has broadened from one single flagship product, TP-5, to four peptide products that make and will make major revenue contributions. The Company ... two state-of-art manufacturing plants and possesses one of the largest peptide synthesizing capacities across Asia. Safe Harbor Statement ...

Nile Therapeutics Provides Update on Phase II CD-NP Clinical Trial for Acute Heart Failure

... patients. About CD-NP CD-NP is a novel chimeric natriuretic peptide in clinical development for the treatment of acute heart failure. CD-NP ... developing its lead compound, CD-NP, a novel rationally designed chimeric peptide in clinical studies for the treatment of heart failure, and CU-NP, a novel ...

Nile Therapeutics Announces Positive Results from Phase 1b Safety and Pharmacodynamics Study of CD-NP in Patients with Heart Failure

... About CD-NP CD-NP is a novel chimeric natriuretic peptide in clinical development for the treatment of ADHF. CD-NP was rationally ... developing its lead compound, CD-NP, a novel rationally designed chimeric peptide in clinical studies for the treatment of heart failure; 2NTX-99, a small ...

ConjuChem and Novozymes Enter Long-Term Supply Agreement for Recombumin(R) use in PC-DAC(TM):Exendin-4

... Novozymes Biopharma has been an integral partner in the development of our peptide conjugation platform. These two Agreements further solidify our ... conjugate has a much longer half-life and efficacy than the peptide alone. The product is a highly soluble liquid formulation that is ...