Metabolism in Biological Technology

Accera, Inc. Launches Neuera Pharmaceuticals, Inc.

... where the mechanism of defective energy metabolism or hypometabolism is involved. Neuera ... provide a real world validation of the energy metabolism platform for Neuera Pharmaceuticals' pipeline ... hallmark of Alzheimer's disease. Defective metabolism of glucose has been shown to precede the onset of ...

XenoTech LLC Offers Drug Industry New Metabolite Profiling Services Following Acquisition of Waters Synapt HDMS System

... scientific consultants with in vitro drug metabolism study data to support its clients' drug discovery ... "We enjoy a very strong reputation for drug metabolism research and for our consultative approach to ... accurate mass," said Paul Toren, Director of Drug metabolism and Analytical Chemistry at XenoTech. "We were ...

Orexigen(R) Therapeutics Announces First of Four Phase 3 Trials of Contrave(R) Meets Co-Primary and Key Secondary Endpoints

... the central nervous system regulates appetite and metabolism as well as the mechanisms that limit weight loss ... to control the balance of food intake and metabolism and another designed to control food preference, ... of treatment by reducing appetite, increasing metabolism and allowing the body to continue losing weight ...

Study From the University of Texas M.D. Anderson Cancer Center Demonstrates That AHCC(R) is Safe in Combination With Most Chemotherapeutic Agents

... agents. As most chemotherapy agents undergo metabolism in the body through the CYP450 (Cytochrome P-450) ... same isoenzymes. The results of this in vitro metabolism study indicated that AHCC is not an inhibitor of ... CYP450 2D6 is not a predominant pathway for metabolism of the most commonly used chemotherapy agents. ...

Life at the jolt

... in their daily diet. By linking bacterial metabolism directly with electricity production, the MFC ... fuel cell, but its relevance to bacterial metabolism has been less clear. The next important concept ... studies have shown that the rate of bacterial metabolism at the anode increases when the electrical ...

Amylin Pharmaceuticals Announces Positive Results from Dose-Ranging Clinical Study of Pramlintide/Metreleptin Combination Treatment for Obesity

... by fat cells that plays a fundamental role in the regulation of energy metabolism and body weight. To date, more than 1,200 overweight or obese individuals ... research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is ...

Orexigen(R) Therapeutics Presents Additional NB-302 Contrave(R) Data at American Diabetes Association (ADA) 69th Scientific Sessions

... system: one associated with controlling the balance of food intake and metabolism and another involved in controlling food preference, reward and cravings. ... weight loss over one year of treatment by reducing appetite, increasing metabolism and allowing the body to continue losing weight by offsetting its natural ...

Orexigen(R) Therapeutics Issued a Key Fourth U.S. Patent on Contrave(R)

... central nervous system: one that controls the balance of food intake and metabolism and another which controls food preference and cravings (also known as the ... over one year of treatment we believe by reducing appetite, increasing metabolism and allowing the body to continue losing weight by offsetting its natural ...

Technique for Creating Authentic Rat Embryonic Stem Cells Published in Cell

... Alternatively, the insertion of genes such as those involved in drug metabolism in the human liver means that knock-in models can provide information on ... researchers to knock-in human genes it will be possible to conduct drug metabolism and toxicology studies with even higher predictability in rats than ever ...

Bionovo Reports Third Quarter 2008 Financial Results

... cancer in the U.S. -- The Company presented an analysis of the metabolism of one of the active chemical ingredients of MF101, the Company's ... Society for Pharmacology and Experimental Therapeutics, Drug metabolism and Disposition, adds to the growing body of data supporting MF101's ...

Molecular Biometrics Announces Results of Parkinson's Disease Research and Receipt of Grant From Michael J. Fox Foundation to Advance Diagnostic Technology

... individual signals from many molecular compounds produced by cellular metabolism which, when evaluated as a whole, represent unique biomarkers of biologic ... disease and Parkinson's disease), maternal fetal medicine, pulmonary metabolism and edema, and lactate metabolism. Molecular Biometrics is privately held ...

IDF Urges Healthcare Providers to Address the Relationship Between Type 2 Diabetes and Sleep Apnea

... P, Person C, Ouksel H, Urban T, Racineux JL: Impaired glucose-insulin metabolism in males with obstructive sleep apnoea syndrome. Eur Respir J22(1): ... T, Awad Tageldin M, Boman G: Sleep-disordered breathing and glucose metabolism in hypertensive men: a population-based study. J Intern Med 249(2): ...

Study Suggests GAMMAGARD LIQUID May Target the Primary Pathway Involved in Alzheimer's Disease

... The oral presentation, "Intravenous Immunoglobulin Increases Brain Glucose metabolism in Alzheimer Disease," will also be presented on April 17 and will discuss the analysis of brain activity using imaging data. The brain metabolism results were based on serial Positron Emission Tomography (PET) scans, an ...

NuRx Pharmaceuticals Retains Russo Partners for Investor Relations, Corporate Communications Counsel

... supportive therapy), the treatment of diabetes, the regulation of lipid metabolism and bone metabolism and repair. The company's lead compounds are (1) NRX4204, a highly ...

Cell Therapeutics, Inc. (CTI) Receives SPA Approval from FDA and Launches Gender-Specific Phase III Trial for Advanced Non-Small Cell Lung Cancer

... studies show the influence of estrogen on the anti-tumor effect and metabolism of XYOTAX and provide the likely scientific basis for the clinical ... chemotherapy. Preclinical and clinical studies support that XYOTAX metabolism by lung cancer cells may be influenced by estrogen, which could lead to ...

Salugen Announces the U.S. Launch of GenoTrim - a DNA Customized Nutritional Solution for Weight Management

... GenoTrim uniquely identifies specific genetic factors affecting hunger, metabolism and body composition that may contribute to the weight challenges of many ... to address the underlying genetic factors involved in hormones and metabolism that Harvard Medical Experts suggest influence 70% to 80% of overweight ...

GeneGo Donates Proprietary Cytokine Pathway Maps to ISICR

... analysis tools enable functions such as determining the biological enrichment and representative networks for a gene (or list of genes), associated metabolism and diseases, and therapeutic drugs complete with supportive links to the public domain literature. Additional tools include full interactome ...

Canadian researchers discover gene related to the appearance of aging

... service. Through genomic research, scientists were able to identify the gene responsible for CL2 in these patients, citing an interruption of the metabolism of the amino acid, proline. The gene, pyrroline-5-carboxylate reductase 1, carries out the final step of proline synthesis. Proline is a major ...

Amylin Pharmaceuticals to Webcast Second Quarter Results

... (pramlintide acetate) injection and BYETTA(R) (exenatide) injection. Amylin's research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Further information on Amylin ...

Santaris Pharma - Interim Report for the Period 1 January to 30 June 2009

... below. Development SPC3649-HCV SPC3649 is a potent and specific inhibitor of microRNA-122 known to be involved in cholesterol metabolism and in hepatitis virus replication in the liver. In April 2009, Santaris Pharma completed a Phase I First-in-Man single dose study of SPC3649 with 60 ...

Evidence for a New Genetic Link to Therapeutic Efficacy for Alzheimer's Disease

... trials, Axona has been shown to safely improve cognitive function and memory in AD patients. Axona addresses the hypometabolism or defective metabolism of glucose that occurs in those areas of the brain that are involved in Alzheimer's disease. Accera engages in research, development and ...

New Drug Application for Exenatide Once Weekly Accepted for Review by FDA

... development and commercialization of innovative medicines. Amylin's research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Through a long-standing ...

Covance Appoints Dr. Steven M. Michael as Vice President and Chief Scientific Officer of Global Bioanalytical Services

... & Metabolism. As a member of the executive leadership team, he provided strategic leadership for the Worldwide Pharmacokinetics, Dynamics & metabolism group and led the regulated bioanalytical support of the Pfizer human health portfolio. Dr. Michael's experience also includes drug discovery, drug ...

deCODE Discovers a Gene Linked to Risk of Kidney Stones and Osteoporosis

... between cells. As calcium is a key component both of most kidney stones and of bone, the deCODE team examined the relationship between CLDN14 and the metabolism of calcium. The results suggest that the SNP may be contributing to increased calcium excretion in urine, a major risk factor for kidney stones and ...

Cordex Completes Production of ATPace(TM) Clinical Trial Material

... based upon the emerging pharmacology of adenosine 5'-triphosphate (ATP) and nitric oxide (NO). These two molecules play critical roles in cellular metabolism and signal transduction, the manipulation of which constitute novel therapeutic modalities for the treatment of major cardiovascular disorders. ...

Amylin Pharmaceuticals to Present at Piper Jaffray Europe Conference

... (pramlintide acetate) injection and BYETTA(R) (exenatide) injection. Amylin's research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Further information about Amylin ...

Springborn Deploys eStudy(TM) Hosted Solution for Management of Global Environmental Testing

... and specialty and industrial chemical industries. Its testing services include avian toxicology , ecotoxicology, environmental fate and metabolism , product and analytical chemistry services. Visit www.springbornsmithers.com for more information. Inquiries: Diana ...

Kuvan Receives Priority Review Status From Health Canada

... 50,000 diagnosed patients in the developed world, is caused by a deficiency of the enzyme phenylalanine hydroxylase. PAH is required for the metabolism of phenylalanine, an essential amino acid found in most protein-containing foods. If the active enzyme is not present in sufficient quantities, Phe ...

Amylin Pharmaceuticals to Present at Goldman Sachs Annual Global Health Care Conference

... (pramlintide acetate) injection and BYETTA(R) (exenatide) injection. Amylin's research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Further information about Amylin ...

Amylin Announces Preliminary Tabulation of Annual Meeting Results

... (pramlintide acetate) injection and BYETTA(R) (exenatide) injection. Amylin's research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Further information on Amylin ...

Roche Announces Back-to-Basics Approach to Diabetes Care - Simpler is Better

... and diagnostics. Roche is the world's largest biotech company with truly differentiated medicines in oncology, virology, inflammation, metabolism and CNS. Roche is also the world leader in in-vitro diagnostics, tissue-based cancer diagnostics and a pioneer in diabetes management. Roche's ...

Poxel SAS Set up to Find Innovative Solutions for Metabolic Diseases Management

... pharmaceutical companies. Its pipeline consists only of innovative projects with new mechanisms of action, with a combined activity on glucose metabolism and other cardiovascular risk factors (lipid disorders and obesity) and with an improved safety profile compared to currently available therapies. ...

Genomas and Institute of Living Among Organizers of Pharmacogenetics Symposium at 2009 Annual Meeting of the American Psychiatric Association

... Papers presented at today's symposium were: Greater Utilization of Psychiatric Services is Associated with Pharmacogenetic Variation and metabolism Deficiencies Gualberto Ruano, M.D., Ph.D., and John W. Goethe, M.D. Genomas Inc. and Institute of Living/Hartford Hospital, Hartford, CT ...

Amylin Responds to Eastbourne Letter

... (pramlintide acetate) injection and BYETTA(R) (exenatide) injection. Amylin's research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Further information on Amylin ...

Amylin Comments on RiskMetrics Report

... (pramlintide acetate) injection and BYETTA(R) (exenatide) injection. Amylin's research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Further information on Amylin ...

Amylin Pharmaceuticals to Present at Deutsche Bank Health Care Conference

... (pramlintide acetate) injection and BYETTA(R) (exenatide) injection. Amylin's research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Further information about Amylin ...

Roche Announces Long-Term Commitment to Tackle Growing Epidemic of Diabetes

... and diagnostics. Roche is the world's largest biotech company with truly differentiated medicines in oncology, virology, inflammation, metabolism and CNS. Roche is also the world leader in in-vitro diagnostics, tissue-based cancer diagnostics and a pioneer in diabetes management. Roche's ...

AMT Starts Preregistration Trial for Glybera(TM)

... and potentially lethal disease. The randomized controlled trial has been designed to gather additional data on the effects of Glybera on lipid metabolism and the mechanisms underlying the prevention of pancreatitis attacks. The trial is being performed under a Clinical Trial Application approved by ...

Exenatide Once Weekly New Drug Application Submitted to FDA for Type 2 Diabetes

... development and commercialization of innovative medicines. Amylin's research and development activities leverage the company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Through a long-standing ...

Amylin Pharmaceuticals Announces a New Sales Approach to Better Target the Diabetes Market

... (pramlintide acetate) injection and BYETTA(R) (exenatide) injection. Amylin's research and development activities leverage the Company's expertise in metabolism to develop potential therapies to treat diabetes and obesity. Amylin is headquartered in San Diego, California. Further information on Amylin ...