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kinetics in Biological Technology

Migenix Takes Operational Actions To Extend Cash Past Upcoming Key Milestones

... - Phase II viral kinetics 12 week study results in Q3/08 CLS001 (rosacea ... planned extension of the celgosivir viral kinetics study to include a 600 mg celgosivir combination ... have results from the celgosivir Phase II viral kinetics study in the third quarter of 2008; our plans to ...

MIGENIX Reports Third Quarter Fiscal Year 2008 Financial Results

... for tolerability, pharmacokinetics and viral kinetics when combined with the standard of care drugs, ... at 600 mg dose in the celgosivir Phase II viral kinetics study and having results from the study in ... the 600 mg dose in the celgosivir Phase II viral kinetics study and having results from the study in the ...

MIGENIX to Add 600mg Daily Celgosivir Dose to Phase II Viral Kinetics Study

... arm to its currently enrolling Phase II viral kinetics study in hepatitis C virus ("HCV") ... The currently enrolling Phase II viral kinetics study is a 12-week randomized, active-controlled ... from the first 10 patients in the current viral kinetics study who had completed 4-weeks of therapy were ...

MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results

... first 10 patients in an ongoing Phase II viral kinetics combination study of celgosivir in patients with ... on the tolerability, pharmacokinetics and viral kinetics when combined with the standard of care drugs, ... to the standard of care drugs alone. The viral kinetics in both treatment groups are similar and, due to ...

DNA Software, Inc. Awarded $2.5 M in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies

... after a long time) of DNA and RNA reactions, none can model the kinetics (i.e. how fast the reaction takes place). In addition, most software can ... tests and therapeutics. DNA Software is combining the unique features of kinetics and modified nucleotides with its existing OMP™ (Oligonucleotide ...

MIGENIX Corporate Update and Requisition of Special Meeting

... assessing 400 mg celgosivir for tolerability, pharmacokinetics and viral kinetics when combined with the standard of care drugs, pegylated interferon ... by the end of 2008; to have results from the celgosivir Phase II viral kinetics study in the next several weeks; MX-2401 being our next clinical program ...

MIGENIX Second Fiscal Quarter 2008 Financial Results Conference Call & Webcast Notification

... Company to Report Interim Celgosivir 4-Week Viral kinetics Study Data on Monday December 3, 2007 VANCOUVER ... the Company will report interim 4-week data from a Phase II viral kinetics combination study of celgosivir in patients with chronic HCV (genotype 1) ...

MIGENIX to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference

... Company Provides Revised Timing on Interim Celgosivir Viral kinetics Study Data VANCOUVER and SAN DIEGO, ... interim 4-week data expected in October from a Phase II viral kinetics combination study of celgosivir in patients with chronic HCV (genotype 1) ...

MIGENIX Reports First Quarter Fiscal Year 2008 Financial Results

... interested parties for the partnering of celgosivir. A Phase II viral kinetics combination study of celgosivir in patients with chronic HCV (genotype 1) ... by the end of 2007; 4-week interim results from the Phase II viral kinetics combination study of celgosivir in approximately 10 treatment-naive ...

ForteBio Launches Two Revolutionary High-Throughput, Label-Free Instruments: The Octet(R) RED384 and the Octet QK384

... drug discovery and development. These systems enable real-time, label-free analysis of biomolecular interactions, providing information on affinity, kinetics and concentration. ForteBio's analytical capabilities enable significantly easier, faster and better characterization of drug candidates, thus ...

ForteBio Launches New Assay Capabilities for High-Sensitivity Protein Quantitation and Fragment Screening on Its Octet(R) Platform

... drug discovery and development. These systems enable real-time, label-free analysis of biomolecular interactions, providing information on affinity, kinetics and concentration. ForteBio's analytical capabilities enable significantly easier, faster and better characterization of drug candidates, thus ...

Angiotech Pharmaceuticals, Inc. announces financial results for the first quarter ended March 31, 2009

... Stents with BSC's first-generation TAXUS Express Stent. While the second-generation TAXUS Liberte Stent uses identical drug dose, polymer and release kinetics as the TAXUS Express Stent, it features thinner struts and a uniform architecture specifically designed for drug delivery. One-year results from the ...

AACR 100th Annual Meeting Highlights Superior Ability of InNexus' DXL-Modified Anti-CD20 Antibody to Attach and Kill NHL With Safety Comparable to Approved Antibody Therapies in Preclinical Studies

... Dose 100-Fold Above The Anticipated Therapeutic Dose ", (AACR# 1231) and " Oxidative Modification Of An Anti-CD20 Antibody Imparts Autophilic Binding kinetics ", (AACR# 1230). Posters and company representatives will also be available within the AACR Antibody and Antibody Targets Session from 1:00-5:00 PM ...

SeqWright to Invest in LaserGen's Novel Lightning Terminators(TM)

... are expected to facilitate LaserGen's effort in achieving that goal. Financial terms of the transaction were not disclosed. The superior kinetics and natural DNA restoration of Lightning Terminators(TM) inform the promise of increased speed, throughput, and read-length, while lowering cost. ...

University of Minnesota Professor Dr. David Pui to Speak at American Filtration and Separation Society Conference

... Also speaking at the Wednesday morning session is Prof. Dr. Gerhard Kasper from the Universität Karlsruhe. He will speak on "The kinetics of Dust Filtration" AFS will also have featured speakers at its' lunches on May 5th and 6th. On May 5th, Elizabeth Carey, Chief Technical ...

Romark Announces Presentation of New Data for Controlled Release Nitazoxanide in Chronic Hepatitis C

... Association for the Study of the Liver (APASL) in Hong Kong. The presentation titled "Controlled Release Tablet Improves Pharmacokinetics, Viral kinetics and Tolerability of Nitazoxanide for Treatment of Chronic Hepatitis C," abstract FP052, was given by Emmet B. Keeffe, M.D. of the Romark ...

Recent Advances in Organic Chemistry Using Real-Time In Situ FTIR

... reaction conditions without sampling, facilitates an understanding of reaction mechanism and pathway, and a comprehensive knowledge of reaction kinetics that offline sampling can never provide. ### Read the full story at http://www.prweb.com/releases/Reaction/Monitoring/prweb1876444.htm . ...

InVitria's Cell Culture Media Components Showcased at WilBio's 2008 Cell Engineering Meeting

... the meeting and revealed data from a study entitled, "Recombinant Human Serum Albumin Expressed in Plants Improves the Productivity and Growth kinetics of CHO." Tests have shown that Cellastim outperforms plasma-derived human serum albumin and can result in improved doubling time and an average ...

Halozyme Therapeutics Begins Phase 2 Clinical Trial of Insulin With rHuPH20 in Type 1 Diabetic Patients

... insulin faster acting, which shifts insulin exposure and glucose lowering activity to earlier times and away from late postprandial times, insulin kinetics and activity for the combination of insulin plus rHuPH20 more closely mimics natural, endogenous prandial insulin release. About Halozyme ...

Stenum Hospital Does its 600th American Disc Replacement Surgery

... when multi-level indications exist, resulting in poor results and risky second surgeries. Stenum Hospital is now using the breakthrough Spinal kinetics M6 implant. This implant achieves the ultimate goal of replicating the healthy human disc. By providing shock absorption and graded variable motion ...

MRI Expands Energy Role: Launches Center for Integrated Algal Research and Creates Director of Energy Programs Position

... species using molecular tools -- developing and purification of seed cultures -- identifying and eliminating bioreactor contamination -- growth kinetics and optimizing growth conditions -- operating open and closed algal bioreactors -- developing and validating harvesting approaches -- devising ...

The Micell Rapid Absorption Polymer DES System to be Presented at TCT 2008

... eliminating the polymer faster than any other biodegradable coating that is commercially available," said Kandzari. "The controlled drug release and kinetics enables a lower drug dose while using known and proven polymers and an approved anti-proliferative drug. Taken together, the Micell DES has the ...

InterMune to Present Four Abstracts on HCV Protease Inhibitor ITMN-191 at the AASLD Meeting

... these abstracts demonstrate that in the experiments conducted, ITMN-191 was safe and very well tolerated in humans and demonstrated viral kinetics that are competitive with other direct anti-viral compounds in development. The safety and viral kinetic profile of ITMN-191 was observed in ...

ForteBio, Inc. Closes $25 Million In Series C Financing

... year ForteBio introduced its Octet RED system and additional biosensors, expanding its quantitation applications and broadening its small molecule kinetics capabilities. The company also added a European direct selling team and numerous distributors throughout the world this year in order to better serve ...

MIGENIX Reports First Quarter Fiscal 2009 Financial Results

... oral alpha-glucosidase I inhibitor; treatment of chronic hepatitis C virus infections): Following the report of interim results from a Phase II viral kinetics study of hepatitis C virus treatment-nave patients in July 2008, we are continuing to seek strategic options for advancing the development of ...

Nebulized Formoterol Fumarate Has Comparable Pharmacokinetic and Pharmacodynamic Profile to Dry Powder Formulation

... study; "A Pharmacokinetic Study in COPD Patients Comparing Formoterol Fumarate Delivered by Nebulization and DPI," showed comparability in linear kinetics and excreted drug levels between formoterol fumarate administered by nebulization and DPI. Transient and dose-related effects on serum potassium, ...

ProMetic to obtain controlling stake in Pathogen Removal and Diagnostic Technologies Inc.

... and goats, and Bovine Spongiform Encephalopathy ("BSE"), a newly emergent disease that affects both cattle and humans. Dr. Rohwer's studies on the kinetics of inactivation of the TSE agents have provided the scientific foundation for disinfection guidelines in the U.S. and worldwide. Recently Dr. Rohwer ...

Prometic to present at the American Chemical Society

... and goats, and Bovine Spongiform Encephalopathy ("BSE"), a newly emergent disease that affects both cattle and humans. Dr. Rohwer's studies on the kinetics of inactivation of the TSE agents have provided the scientific foundation for disinfection guidelines in the U.S. and worldwide. More recently Dr. ...

MIGENIX releases CEO message #22

... Phase III results in H2/08 - NDA submission in H1/09 - Rest of world partnership Celgosivir (hepatitis C virus): - Phase II viral kinetics study results (including 600mg) in Q3/08 - Partnership CLS001 (rosacea and other dermatologic conditions): - Enter Phase III clinical ...

Clontech Laboratories, Inc. Releases the ProteoTuner(TM) Systems

... Lou, General Manager of Clontech Laboratories, Inc. Clontech's ProteoTuner systems have broad applications in basic and applied research. The fast kinetics of protein stabilization/destabilization make it possible to study transient effects of the protein of interest that might otherwise have been ....

Odyssey Thera Granted U.S. Patent for Animal Imaging

... used at Odyssey Thera to monitor drug response. The invention makes it possible to monitor specific biochemical parameters, including the extent and kinetics of drug target modulation, in a live subject. "This patent extends our broad estate in drug discovery technologies," said John K. Westwick, Ph.D., ...

Acrylamide Polymerization A Practical Approach

... Gelfi C and Righetti PG, Polymerization kinetics of polyacrylamide gels I. Effect ... Gelfi C and Righetti PG, Polymerization kinetics of polyacrylamide gels II. Effect ... Righetti PG et al., Polymerization kinetics of polyacrylamide gels. III. Effect ...

Calcium Flux Assays using the LabChip 3000

... cells can be detected (Step 3). Once feasibility has been established, the kinetics and magnitude of response to agonist exposure is measured (step 4) and, in ... than ten times the baseline noise. 4. Determine kinetics of Response The LabChip 3000 calcium flux chip is designed ...

Who is minding the Innovation Gap?

... Memorial Day redux Most chemical reactions involve a sequence of steps from initial reactants to final products. It is a well known law of kinetics that the overall rate of a reaction is determined by the slowest (or rate-limiting) step in that process. The Innovation Gap is more than just a sad ...

FERMENTATION BASICS

... when to terminate the process and/or to transfer or harvest the product * Calculating the mass and thermal balances, rates of reaction, kinetics and yields (see Table 4) * Providing information for statistical records on consistency and for archival purposes * Monitoring ...

Calcium Plus Assay Kit, Superior Detection for Specialized Targets

... higher and more distinct. Additionally, tighter CVs across 96- and 384- well plates are observed. Figure 2 illustrates the difference in kinetics and dynamic range between the equivalent concentrations of RANTES and MIP1a. RAPID ASSAY DEVELOPMENT ...

Luciferase Reporter Gene Cells and Recombinant Luciferase Dilutions Studied with the CLIPR Luciferase Assay Kit and the LMax Microplate Luminometer (MaxLine Application Note #38)

... measured easily withan Lmax microplate luminometer. The CLIPR Luciferase Assay reagent was originally developed for use in aglow kinetics mode in the Molecular Devices CLIPR high throughputmicroplate luminometer. However, the reagent can also be used in a flash modeto measure cell-based ...

QBT Fatty Acid Uptake Assay Kit datasheet

... OPTIMIZED ASSAY The QBT Fatty Acid Uptake Assay is a single-step homogeneous fluorescent assay that provides real-time uptake kinetics and is ideally suited for high throughput screening applications in both 96-well and 384-well formats. The kit employs a BODIPY -dodecanoic acid ...

Receptor Binding Assays using Fluorescence Polarization Detection: the [FP]2TM Characterized Tracers

... binding to GPCR targets. In addition to the eight ligands described here, fully optimized kits (pharmacology, assay performance, DMSO tolerance, kinetics and stability) are available. See [FP] 2 brochure, reference number H78392, for more detailed lists. Principles of Fluorescence ...
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