Ion in Biological Technology

Waters Introduces New SYNAPT G2 with Greater Power, Versatility and Speed Than Any Other High-End Mass Spectrometer

... dynamic range and enhanced (high-efficiency) ion mobility resolution that is truly game-changing." ... G2 will displace generic QTof and electrostatic ion trap systems as the de facto choice in high-end ... pusher and dual stage reflectron with a novel ion detection system in an optimised, folded, TOF ...

ChanTest Awarded $4.8 Million Through the Ohio Third Frontier Research and Commercialization Program

... 6 /PRNewswire/ -- ChanTest, the leading expert in ion channels and GPCRs (G-protein coupled receptors) ... million grant to expand its library of validated ion channel and GPCR cell line products and services, ... our development of the world's most comprehensive ion channel library, which now covers half of the ...

Cellectricon and BioFocus DPI Advance High Throughput ion Channel Drug Discovery

... research organization with leading expertise in ion channel screening. BioFocus DPI will ... capacity, particularly for fast ligand-gated ion channels. "Cellectricon's unique high ... us to further develop our leading platform for ion channel screening. This collaboration gives us ...

X marks the spot: Ions coldly go through NIST trap junction

... and Technology (NIST) have demonstrated a new ion trap that enables ions to go through an ... critical to information processing. The new ion trap, a rectangle roughly 5 by 2 millimeters in ... electrodes. It is more complex than previous NIST ion traps, with 46 electrodes supporting ...

ChanTest Acquires Applied Cell Sciences

... Feb. 26 /PRNewswire/ -- The leading experts in ion channels and GPCR (G-protein coupled receptors) - ... are now united. ChanTest, the leading provider of ion channel testing services and validated cell ... the most-comprehensive portfolio available of ion channel and GPCR services, reagents, and cell ...

A supercharged metal-ion generator

... says Anders, "under certain conditions, the ion current can greatly exceed the discharge ... rate. When the voltage is high enough, the ion current does not fall off as the gas is depleted ... electrons). At low to moderate power levels the ion current reaches a preliminary maximum, and then ...

Prosolia and Indigo BioSystems Come Together to Create FireFly(TM) Data Conversion Software for Mass Spectrometers

... LTQ mass spectrometer and Omni Spray (R) ion Source users now have the capability to convert ... data sets, Prosolia's Omni Spray ion Source can routinely generate in combination ... Prosolia continues to build upon the Omni Spray ion Source product and produce advanced platforms, ...

Prosolia to Introduce Omni Spray(R) Ion Source in 2-D Format

... Inc. introduces a new advanced Omni Spray ion Source model based on the Desorption Electrospray Ionization (DESI) technology. The Omni Spray 2-D ion Source has an automated surface platform which ... micro-titer plate. The Omni Spray 2-D ion Source achieves a step resolution down to ...

Cellectricon Partners With The Automation Partnership - Bringing Next Generation Ion Channel Screening System to Market.

... Cellectricon's next generation high throughput ion channel screening platform. Dynaflow(R)HT will be ... Addressing the limitations of current ion channel screening technologies, the Dynaflow(R)HT ... system to the market is a milestone for ion channel screening. The system offers unmatched ...

Cyprotex Purchases Applied Biosystems Sciex QTRAP(R) 5500 LC-MS/MS

... in their facilities of one of the most sensitive ion trap and triple quadrupole instruments in the ... most sensitive and fastest scanning linear ion trap. It combines exceptional quantitative and ... capability, and allows accurate and precise ion detection over a wide dynamic range. The ...

Cold atoms could replace hot gallium in focused ion beams

... into a wide variety of targets. In principle, ion beams also could produce better images of ... the brightness or intensity necessary for the ion beam to cut into most materials. The NIST team ... different approach to generating a focused ion beam that opens up the possibility for use of ...

Dendreon Presents Preclinical Data Validating Anti-Tumor Activity of D-3263, a Trp-p8 Agonist

... titled, "Preclinical Validation of the TrpM8 ion Channel as a Cancer/ Benign Prostate Hyperplasia ... Dendreon's in-house discovery efforts. It is an ion channel that is triggered by cold temperatures ... small molecule agonists that activate the Trp-p8 ion channel and induce cell death. About Dendreon ...

ChanTest to Highlight the World's Largest Catalog of Ion Channel-Expressing Cell Lines and Discovery Services at Assays & Cellular Targets Conference, Booth 11

... CEO is featured speaker: "Case Study - Screening ion Channels for Safety and Efficacy" on ... -- ChanTest will feature its expanding line of ion channel services and cell lines for ... San Diego, September 24-26. ChanTest designed its ion channel cell lines and services to provide ...

ChanTest to Highlight the World's Largest Catalog of Ion Channel-Expressing Cell Lines and Discovery Services at Ion Channel Targets, Booth 5

... -- ChanTest, the preeminent provider of validated ion channel-expressing cell lines and services for ... services and cell lines in booth 5 at the ion Channel Targets conference in San Francisco ... 9th at 2:30. "There are 400 genes encoding ion channels in the human genome, and countless ...

ChanTest Launches New Business to Provide Validated Ion Channel Expressing Cell Lines to the Research Community

... ChanTest, the world-leading provider of validated ion channel-expressing cell lines and services for ... lines that the company has validated on the major ion channel platforms, including manual patch clamp, ... available during 2008 to 64. "As the preeminent ion channel company, our goal is to serve all the ion ...

ChanTest to Highlight the World's Largest Catalog of Ion Channel-Expressing Cell Lines and Discovery Services at Drug Discovery Technology, Booth 839

... Company CEO to present talk: "Successes Using ion Channel Targets for Repurposed Drugs" on ... role as the preeminent provider of validated ion channel-expressing cell lines and services ... be exhibiting in booth 839 its expanding line of ion channel services designed to give drug-discovery ...

Cellectricon and AstraZeneca - Partners in New High Throughput Ion Channel Drug Discovery Technology

... high throughput platform, Dynaflow(R)HT, for ion channel screening. Cellectricon and AstraZeneca ... collaboration aims to accelerate our efforts in ion channel drug discovery and has been very fruitful ... academic and industrial research in ion channel drug discovery. I am happy to see us ...

ChanTest Launches Redesigned Web Site

... at a click of a button, to consult a ChanTest ion channel expert. We also take seriously our ... in learning more about the importance of ion channels in drug safety. An explanation of the ... and events. About ChanTest The preeminent ion channel services company, ChanTest serves its ...

China Sun Group High-Tech Co. Completes Share Exchange to Create 100% Ownership in DLX Subsidiary

... Group") produces anode materials used in lithium ion batteries. Through its wholly-owned ... state-of-the-art components for advanced lithium ion batteries. Leveraging its state-of-the-art ... ore to finished products, including lithium ion batteries. For more information, visit ...

ChanTest to Highlight Most-Comprehensive Range of Ion Channel Profiling Screens and Consultation Services at 14th Annual SBS Conference, Booth 1104

... SBS conference the company's expanding line of ion channel services designed to give drug-discovery ... the drug-discovery process, ChanTest's functional ion channel screens can save considerable time, ... the functional effects of drugs directly on ion channel currents. For higher-throughput ...

ChanTest to Highlight Expanded Ion Channel Testing Services for Preclinical Safety at ToxExpo, Including the World's Largest Catalog of Validated Ion Channels, Booth 2504

... we've designed our comprehensive range of ion channel assays, follow-up models, and ... trials. ChanTest is the most experienced ion channel services company in the world. Our ... accurate, and reliable results. We specialize in ion channel screening. Customers count on ChanTest ...

Sigma Launches The New Ion Channel Solutions Brochure and Web Site

... Cell Biology solutions through the new ion Channel Solutions Brochure and ion Channels Web site ( ... elucidation of ion channel function. The Sigma ion Channel Solutions Brochure provides a scientific ...

Treatment blocks pain without disrupting other functions

... in this study is unique in that it uses a type of ion channel (TRPV1 channels) as an avenue to deliver medication. ion channels are pores in the cell membrane that ... from expression of dozens of different types of ion channels. Some of ...

New target for anti-flu drug development

... homeostasis. M2 protein of flu virus forms ion channels allowing ion trafficking into cells that cells no longer ... M2 kills mammalian cells, but also showed that ion channeling through M2 pores may be a molecular ...

A molecular ripcord for chemical reactions

... work; weakest link The researchers packed a catalytically active metal ion completely in using two molecular caps (ligands). They attached two ... end was now broken off from the active metal ion, which allowed the metal ion to become catalytically active. In other words, it could now accelerate ...

Peter Zoller and Ignacio Cirac, awarded by the BBVA Foundation

... for a quantum computer. They based their conjectures on what are known as ion traps, in which electrically charged and cooled atoms are trapped by an ... prototypes of quantum computers have already been built based on the ion trap idea. In the last few years, work done at numerous laboratories has ...

Researchers develop new model for cystic fibrosis

... a person inherits two mutated copies of the CFTR gene leading to loss of ion channel function that adversely affects many organs. To create the CF ... The researchers established that piglets lacking CFTR have the abnormal ion channel activity that is a hallmark of CF disease. They also showed that ...

NIST studies how new helium ion microscope measures up

... mechanisms of this new technology. The clearest advantage of the helium ion microscope is that the images show the actual edge of a sample better than ... processes. NIST received the first-ever commercial helium ion microscope, called Orion, from Carl Zeiss, Inc., last summer as part of a ...

New FTMS System From Varian, Inc. Offers Switchable LC and GC Sources and True Triple Quadrupole Capabilities

... a true triple quadrupole mass spectrometer with its own off axis ion detector independent of the FT cell in the magnet. The choice of two ... pending) that allows rapid changing (e.g. GC to LC) or maintenance of ion sources without the long down time required when venting the ultra high ...

RG Global Corporate Update: First Coal Bed Methane Water Treatment Plant Near Completion; Expanding Water Treatment Applications

... end of February on its first plant employing the Catalyx Fluid Solutions ion exchange technology to treat water discharged during the harvesting of ... in negotiations with multiple companies for additional applications of its ion exchange technology, which can be used to remove nitrates, arsenic, sodium ...

Aureus Pharma Announces Renewal and Expansion of Licensing Agreement With Bristol-Myers Squibb for its AurSCOPE Knowledge Databases

... Aureus' AurSCOPE GPCR, and has also licensed Aureus' AurSCOPE Kinase and ion Channel Knowledge databases. Aureus Pharma's target-family-based AurSCOPE ... access to knowledge for important drug target classes including GPCR, ion Channel, Kinase as well as other critical pharma topics including ...

Bruker Announces Availability of New HUPO World Congress Proteomics Posters on Web Site

... and General Mass Spectrometry -- Novel CID Fragmentation Techniques in ion Traps for Improved Peptide Characterization Poster M103 -- Sequence ... Characterization by the Combination of High Resolution-CID and ion Trap-ETD Poster T345 -- Automated LC-MALDI Analysis of Glycopeptides from ...

Stevens researchers provide new information about mass spectrometry

... and mechanistically rationalized. For example, the spectrum of m/z 121 ion of deprotonated ortho-hydroxybenzaldehyde shows an intense peak at m/z 93 ... heterolytic fragmentation mechanism. In contrast, the m/z 121 ion derived from meta and para isomers undergoes a charge-remote homolytic ...

HUYA Bioscience International Licenses Clinical Stage Anti-Arrhythmic Compound from the Shanghai Institute of Materia Medica

... compound, HBI-3000 or sulcardine, exhibits a unique profile of myocardial ion channel regulation, compared to approved US and European anti- arrhythmic ... of Product Development at HUYA, commented that "the compound displays an ion channel selectivity profile that may contribute to effective treatment of ...

IBM and Imago find a crucial difficulty in semiconductor device scaling

... properly Cottrell atmospheres) of dopant atoms form around defects after ion implantation and annealing. Furthermore, these atmospheres persist in ... enable nanotechnology. Previously, researchers have used secondary ion mass spectrometry (SIMS) and transmission electron microscopy (TEM) to ...

Rapid heating prepares energy-saving zeolite for greater role in industrial separations

... crystalline aluminosilicate materials whose compositions and nanoporous structures can be fine-tuned for applications in catalysis, adsorption and ion exchange. They are called "molecular sieves" because their pores, being small and very uniform in size, can sort and separate molecules selectively ...

Solace Pharmaceuticals Appoints Professor David Julius, Renowned Pain Physiologist, to Scientific Advisory Board

... response to tissue or nerve injury. Professor Julius discovered that capsaicin, the main pungent ingredient in chili peppers, activates an excitatory ion channel, called TRPV1, on sensory nerve endings, and that TRPV1 functions as a molecular integrator of physical and chemical signals that regulate ...

University of Lodz Invests in the Unique Cellaxess(R)HT System for Research on Multidrug Resistance Genes in Cancer

... development, the Cellaxess(R)HT System enables high throughput transfection in genomic screening and the Dynaflow(R)HT System greatly advances ion channel drug discovery. Contact Details: Jonas Ohlsson, CEO Phone: +46(0)709-73-47-92, E-mail: jonas.ohlsson@cellectricon.com ...

NIH funds support UAB joint replacement research

... joint replacement procedures are recurrent, or revision, surgeries. Vohra said the nanostructured diamond-coated devices should reduce the metal ion release to the surrounding tissues and perform better during long-term implantation in the human body, which could significantly cut the follow-up ...

Covance Appoints Dr. Steven M. Michael as Vice President and Chief Scientific Officer of Global Bioanalytical Services

... including Analytical Chemistry, Journal of Pharmaceutical and Biomedical Analysis, and International Journal of Mass Spectrometry and ion Process. Offering global flexible capacity and more than 350 bioanalytical scientists with more than 2,600 years of combined industry ...