Intermediate in Biological Technology

Hutchinson Center Receives $7.6 Million Federal Grant to Study How Genetic Variations Influence Risk of Common Diseases

... by looking at the associations between these genetic variations and intermediate biomarkers of disease, such as cholesterol levels as a marker for heart ... biological data that will permit us to link genetic variants to relevant intermediate biomarkers that will potentially provide important clues to the biological ...

Three Steps to Boost Asymchem's Investment in China

... these production modules with a total output of approximately 20mt of cGMP intermediate and APIs each year are designed according to international concepts and ... is the third one of Asymchem in the new Binhai area aims to produce cGMP intermediate and APIs on large scale following ICH Q7A guidelines. Recently, Asymchem ...

Atherotech Taps Canyons Medical Center Director, Lipidologist as Chief Medical Officer

... dozen cardiovascular and metabolic testing panels, including C-Reactive Protein (hsCRP), ApoE genotype and NT-proBNP for assessment of patients at intermediate to high risk of cardiometabolic diseases. Atherotech continues to add advanced and follow-up cardiovascular disease (CVD) risk profiles. ...

Pixantrone Significantly Increases Complete Remissions, Overall Response Rates, Frequency of Durable Remissions and Progression Free Survival in Patients with Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

... prior treatments with 50% of patients having failed three prior chemotherapy treatments. More than 70% of the patients on both arms were considered intermediate to high risk by the International Prognostic Index score (>=2). The median prior doxorubicin equivalent dose was approximately 300 mg/m2, the dose ...

Laboratory Test May Predict Effectiveness of ERBITUX(R) for Individual Colorectal Cancer Patients

... curves of the 54 primary colorectal cultures revealed that eight (8) percent of the cultures tested were responsive to cetuximab, 22 percent had an intermediate response, and 70 percent were deemed non-responsive. These results are consistent with a reported clinical response for cetuximab in colorectal ...

Pfizer Global R&D Presents 2008 Top Intermediates CMO Award to Asymchem

... was the first in an annual series to be presented to high performing chemical intermediates suppliers. "A global network of high-quality chemical intermediate manufacturers is critical to enable Pfizer to create and sustain a competitive advantage," said Laurie Chipperfield, Director of API Strategic ...

10,000 New Jobs, Investments Increased

... over its international competitors: a reliable energy supply, combined production potential, and the sharing of costs for raw materials and intermediate goods. Research Network The unique network of university and independent research institutes is a further advantage for Germany as a ...

Scientists determine the structure of highly efficient light-harvesting molecules in green bacteria

... the genes were responsible for improving the bacteria's light-harvesting capabilities. "Essentially, we went backward in evolutionary time to an intermediate state in order to understand, in part, why green bacteria acquired these genes," Bryant said. The team found that the more evolved, wild-type ...

The first DFG research centers to be funded for another 4 years

... Centre in Berlin and the "Molecular Physiology of the Brain" Research Centre in Gttingen were established in 2002 and, following their first positive intermediate evaluation in 2006, will again be reviewed in the coming year. The youngest institution is the "Regenerative Therapies" Research Centre in Dresden, ...

Atherotech to Exhibit its VAP(R) Cholesterol Test at Internal Medicine 2009 in Philadelphia

... risk factors such as Lp(a), remnants and small dense LDL. Atherotech recently announced the addition of more than a dozen tests for patients at intermediate to high risk of cardiometabolic diseases. The new test panels are available immediately and also include homocysteine, creatinine, creatine kinase ...

Atherotech Unveils New Cardiometabolic Test Panels

... Atherotech is adding more than a dozen new tests, including C-Reactive Protein (hsCRP), ApoE genotype, and NT-proBNP, for assessment of patients at intermediate to high risk of cardiometabolic diseases. The company is also adding advanced and follow-up cardiovascular disease (CVD) risk profiles. "We're ...

New Discoveries on a Fingertip Test for Screening Silent Heart Disease Promising Results of Recent Clinical Studies to be Presented during the 2009 American College of Cardiology Conference, March 29th - April 1st in Orlando

... so impressed that I have personally incorporated VENDYS into my office practice, and I believe it can improve risk assessment in patients with low to intermediate Framingham risk." About Endothelix Endothelix Inc. is based in Houston, Texas. The company is positioned as the first to incorporate ...

Waters Corporation Continues to Meet Today's Challenges for Improved Laboratory Operations with New Products at Pittcon 2009

... same QTof or tandem quadrupole mass spectrometer. With this added flexibility, scientists can analyze volatile and semi-volatile compounds of low and intermediate polarity traditionally analyzed by dedicated GC/MS instruments. Switching from an electrospray ionization source in LC/MS/MS mode to the APGC ...

Arpida Announces Full Year 2008 Financial Results

... external experts and the FDA to develop a roadmap to approval. The regulatory filing in the European Union is ongoing. Arpida has received an intermediate report from the European Medicines Agency (EMEA) containing the findings of the review carried out so far. The company is working closely with EMEA ...

VAP Cholesterol Test Helps In Search For New Heart Disease Drugs

... of mutation carriers included: significantly lower levels of non-HDL, very low density lipoprotein (VLDL), VLDL3 (the most-dense VLDL subfraction), intermediate density lipoprotein (IDL), real LDL, and remnant lipoprotein cholesterol. Higher (cardioprotective) levels of both HDL2 and HDL3 cholesterol were ...

Cylene Pharmaceuticals Initiates Phase II Clinical Trial of Quarfloxin (CX-3543) in Patients With Carcinoid/Neuroendocrine Tumors

... in the tissues in which C/NET arise." In this open-label Phase II trial, quarfloxin will be administered to patients with low or intermediate grade C/NET, including those receiving concomitant treatment with a stable dose of octreotide. This multi-centered study will include an assessment ...

Hovione Buys Pfizer's Loughbeg API Facility

... produce spray-dried formulations. Hovione is the world's leading provider of GMP spray-drying services covering every scale (lab, pilot and several intermediate production scales) and is able to provide R&D support and commercial manufacturing. At a time when most fine chemical producers are ...

ScinoPharm Granted US Patent for Novel Crystal Forms

... irinotecan hydrochloride. ScinoPharm has already been granted a US Patent No. 7,157,179 covering the proprietary process for the preparation of a key intermediate of irinotecan hydrochloride. The present invention provides crystalline forms of irinotecan hydrochloride that are more easily filtered from ...

Sigma-Aldrich Introduces MISSION(R) In VIVO QUALITY and iScale Oligos(TM) siRNA, a Superior Quality siRNA Designed for RNAi Research in Animal Models

... siRNA required for RNAi research in animal models. These siRNA are believed to be well suited to target validation and pre-clinical siRNA testing. intermediate and large synthesis scales and a wide variety of modifications are also available. "Increasingly, RNAi researchers are utilizing animal ...

Vermont Surgeon Implants First Accommodating Crystalens in Russia

... distance vision but also reported improved near vision. Tatiana was very happy with the result because she now enjoys a broad range of distance, intermediate and near vision. Like other Crystalens patients, she is enjoying improved functional vision and a better quality of life," added Dr. Singer. Dr. ...

Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy

... from one risk category to another of a significant proportion of the overall cohort. The impact was most pronounced in the categories of intermediate risk, in which individuals were estimated to be at a 5-10% risk of CHD in the next ten years, and intermediate-high, with individuals at an estimated ...

VAP(R) Cholesterol Test Helps Researchers Identify Treatment Effects of Combination Therapy

... was achieved by examining their effects on individual lipoprotein subclasses. Cholesterol associated with very low density lipoprotein (VLDL), intermediate density lipoprotein (IDL), LDL and HDL subfractions was quantified using the Vertical Auto Profile method. LDL particle size was determined ...

Dry Eye Survey: Ophthalmologists Cite Treatment Limitations/Gaps in Treatment of Moderate to Severe Dry Eye

... eye, where it gently dissolves to provide lubrication and protection to the surface of the eye. Lacrisert provides practitioners and patients with an intermediate treatment option between artificial tears and more aggressive treatments. Treatment Goals and Considerations In other survey results, the chief ...

Positive Study Results for Ceftaroline Phase III Clinical Study for the Treatment of Complicated Skin and Skin Structure Infections Presented at ICAAC / IDSA

... used an in vitro model system to compare the activity of ceftaroline with vancomycin. Ceftaroline was more active against a S. aureus strain with intermediate susceptibility to vancomycin and showed similar or superior activity against MRSA, suggesting that it may provide a new option for the treatment of ...

Volcano Corporation Announces Launch of PrimeWire(TM) Pressure Guidewire and s5-FFR Option for Existing Fleet of s5 IVUS Consoles

... not treated with PCI based on FFR guidance achieved long-term outcomes out to five years equivalent to patients who underwent PCI for similar intermediate lesions. DEFER outlines a revascularization strategy for angiographically equivocal stenoses that deploys FFR technology to identify and treat only ...

Dragon to Present at BioContact Quebec 2008

... in Vancouver, Canada, is a leading manufacturer and distributor of a broad line of high-quality antibiotic products including 7-ACA, a key intermediate to produce cephalosporin antibiotics, clavulanic acid, and formulated cephalosporin antibiotic drugs. Dragon is the third largest 7-ACA producer and ...

AdvanDx Receives FDA 510(k) Clearance for Yeast Traffic Light PNA FISH(TM)

... used antifungal agents. While C. albicans and C. parapsilosis are generally susceptible to the antifungal drug fluconazole, C. tropicalis may display intermediate resistance to the drug while C. glabrata and C. krusei display the highest level of fluconazole resistance.(2) At the same time, recent reports ...

MEMC Provides Update on Hurricane Ike

... significantly, the company will issue another press release. About MEMC MEMC is a global leader in the manufacture and sale of wafers and related intermediate products to the semiconductor and solar industries. MEMC has been a pioneer in the design and development of wafer technologies over the past four ...

Pharmasset Reports Preliminary Results of a 4-week Proof-of-Concept Combination Study of R7128 for the Treatment of Chronic Hepatitis C in Genotype 2 or 3 Non-Responders

... therapy for chronic HCV infection. Cohort 1 administered R7128 500mg BID, Cohort 2 administered R7128 1500mg BID, and Cohort 3 administered an intermediate dose of 1000mg BID, all given in combination with pegylated interferon and ribavirin for 28 days. All subjects then went on to receive a total of 48 ...

Advance brings low-cost, bright LED lighting closer to reality

... "It all starts with silicon, which is a single crystal, and you end up with gallium nitride that's oriented with respect to the silicon through these intermediate layers of zirconium nitride and aluminum nitride," Sands said. "If you just deposited gallium nitride on a glass slide, for example, you wouldn't get ...

Discovery by UC Riverside physicists could enable development of faster computers

... are reflected back, leaving electrons with zero net spin in the semiconductor. But the surprising result for the researchers was that at an intermediate thickness, ranging from two to six atomic layers, the selectivity of the interface completely changes. "We see a dramatic and complete reversal in ...

Boston Scientific Welcomes Revised Outlook From Fitch Ratings

... has paid down $1.7 billion of debt during the past 12 months. Fitch added that it expects Boston Scientific's leverage will decline further in the intermediate term through increased cash flow growth and debt reduction. "We welcome this revised outlook and see it as another indication that we are moving in ...

EnzySurge, Maker of DermaStream(TM), Completes Funding Round of US$4 Million

... EnzySurge is currently completing the 2nd phase of a multi-centered, double blind clinical trial focused on chronic leg ulcers (venous ulcers). The intermediate results of the trial indicate a significant improvement and acceleration in treatment. "I am very excited about the results of our most recent ...

SAFC Hitech Introduces Large Scale Bubbler for Compound Semiconductor Production

... proven for many years, and our new EpiVapor unit builds on this technology for true, large-scale operation, with the OM700 now offering an attractive intermediate solution." The OM700 system is presently available. For more information, please visit http://www.safchitech.com . About SAFC Hitech: SAFC ...

Sumitomo Corporation of America Named Exclusive Distribution and Sales Agent for Chiral Quest

... sales agent for Chiral Quest in Japan and selected worldwide accounts. More than 40 percent of the ethical drugs manufactured today utilize chiral intermediate technology. Chiral chemocatalysts play a key role in the manufacture of medicines, fine chemicals, agricultural chemicals, and flavors and ....

Dragon Pharma announces 2007 full year financial results

... in Vancouver, Canada, is a leading manufacturer and distributor of a broad line of high-quality antibiotic products including 7-ACA, a key intermediate to produce cephalosporin antibiotics, clavulanic acid, and formulated cephalosporin antibiotic drugs. Dragon is the third largest 7-ACA producer and ...

Codexis Names David Anton VP Bioindustrials R&D

... and biocatalysis. He led the process research, development and commercialization of several products, including 1,3 propanediol (a chemical intermediate used in a variety of industrial applications ranging from airplane deicing fluids to textiles and carpet). As Vice President, Research and ...

Dragon retains leading investor relations firm

... in Vancouver, Canada, is a leading manufacturer and distributor of a broad line of high-quality antibiotic products including 7-ACA, a key intermediate to produce cephalosporin antibiotics, Clavulanic Acid, and formulated cephalosporin antibiotic drugs. Dragon is the third largest 7-ACA producer and ...

Dragon announces new product launch; increase in annual production output capacity

... in Vancouver, Canada, is a leading manufacturer and distributor of a broad line of high-quality antibiotic products including 7ACA, a key intermediate to produce cephalosporin antibiotics, Clavulanic Acid and formulated cephalosporin antibiotic drugs. Dragon is the third largest 7ACA producer and ...

Making gas out of crude oil

... says. That will help us with thermal recovery processes such as SAGD (steam-assisted gravity drainage). The research team also discovered an intermediate step in the biodegradation process. It involves a separate family of microbes that produce carbon dioxide and hydrogen from partly degraded oil, ...