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Insulin in Biological Technology

Sanofi-aventis Announces Second Quarter 2009 Results

... Net sales of Lantus ((R)) , the world's leading insulin brand, rose by 26% in the second quarter (to euro ... is one of the world's largest and most modern insulin production facilities, and will increase our insulin production capability. On June 26, 2009, ...

Patton Medical Devices Partners With Unomedical to Develop and Market the i-port Advance(TM) Injection Port for People Taking Multiple Daily Injections

... to the inserter technology used to apply most insulin pump infusion sets. Based on feedback received ... in designing and manufacturing high quality insulin delivery devices is a perfect match for bringing ... has been a leading provider of infusion sets for insulin pump therapy worldwide since the mid 1980's, and ...

Oramed Pharmaceuticals Reports Positive Results From a Study of Oral Insulin Capsule on Type 1 Diabetic Patients

... results from a Phase 2A study of its oral insulin capsule, ORMD-0801, on type 1 diabetic patients. ... in type 1 diabetic patients. Oramed's oral insulin capsule, (ORMD-0801), was well tolerated ... and no serious adverse events were observed. The insulin absorption was not affected when given before ...

Insmed Announces Results of IPLEX(TM) Phase II Trial in Myotonic Muscular Dystrophy

... Trial for IPLEX(TM) in MMD Patients with Severe insulin Resistance - RICHMOND, Va. , June 25 ... gastrointestinal function, pain, quality of life, insulin sensitivity, lipid metabolism, and safety and ... demonstrate improvements in standard measures of insulin sensitivity and reductions in fasting glucose, ...

Data for SemBioSys' insulin to be presented at the American Diabetes Association's 69th Scientific Sessions

... of the Phase I/II study with its biosimilar human insulin in a late-breaking scientific poster at the ... and Clinical Bioequivalence of Recombinant Human insulin from Transgenic Plants," by Joseph Boothe and ... clinical study of SBS-1000, a recombinant human insulin manufactured using the Company's proprietary ...

VIA Pharmaceuticals' DGAT1 Inhibitors Featured in American Diabetes Association Poster Presentation

... N. Morial Convention Center Session: insulin Action - Metabolism Title: Can DGAT Inhibition Improve insulin Sensitivity? (Poster 1279-P) DGAT1 ... have been shown to induce weight loss and improve insulin sensitization, glucose tolerance and lipid ....

Hospira Announces Plans to Integrate Symbiq(R) and EndoTool(R) Technologies

... It calculates the dose of intravenous (I.V.) insulin needed to effectively control blood glucose ... identifies individual patient responses to I.V. insulin to help manage current and predict future dosage ... the traditional paper-based system used to manage insulin treatment, EndoTool helps clinicians maintain the ...

SemBioSys provides update on insulin program

... its proprietary plant-produced recombinant human insulin program. In December 2008, SemBioSys announced ... proprietary plant-produced recombinant human insulin to be used primarily for AFRESA(TM), MannKind's ultra-rapid acting insulin product. At the time the option was taken, ...

SemBioSys Genetics Inc. Announces Clinical Results with Plant-Produced Insulin

... clinical study of SBS-1000, a recombinant human insulin manufactured using its proprietary platform. The ... SBS-1000 was bioequivalent to a recombinant human insulin with the expected safety profile. ... Lilly's Humulin(R) R, a widely-used human insulin in North America, meeting all four of the ...

MannKind Submits NDA for AFRESA for Treatment of Diabetes

... feature that distinguishes AFRESA from all other insulin products is not the route of administration - it ... upon contact with the lung surface, releasing insulin monomers that rapidly enter the bloodstream. AFRESA achieves peak insulin levels within 12-14 minutes of administration, ...

Tolerx Expands Phase 3 'DEFEND' Trial of Otelixizumab in Europe

... C-peptide levels (a surrogate of endogenous insulin secretion) and by measuring reductions in the amount of injected insulin used to maintain excellent glycemic control. ... diabetes, will reduce the amount of administered insulin required to control blood glucose levels by ...

MannKind Agrees with Pfizer on the Purchase of Frankfurt Insulin Manufacturing Plant

... Pfizer Inc. (NYSE: PFE ) to purchase Pfizer's insulin facility at Industriepark Hoechst, Frankfurt am ... the production equipment, a quantity of bulk insulin and a license to manufacture bulk insulin for use in pulmonary delivery. The aggregate ...

FDA Approves Apidra(R) SoloSTAR(R) - a Prefilled Disposable Insulin Pen

... - Apidra(R) SoloSTAR(R) is a Convenient insulin Delivery Device to Help Patients with Diabetes ... prefilled disposable pen containing rapid-acting insulin analog Apidra(R), which is indicated to improve ... of their insulins convenient. Basal-prandial insulin regimens that combine once-daily Lantus(R) as a ...

Mindset BioPharmaceuticals (USA) Inc Obtains Notice of Allowance for European Patent Related to Use of Insulin Sensitizers in Senile Dementia, Dementia and Memory Loss

... to patent applications describing the use of insulin sensitizer drugs for the prevention and treatment ... results from resistance to the action of insulin. insulin sensitizer drugs such as Rosiglitazone and ... Several clinical studies have shown that these insulin sensitizer drugs improve learning and memory. ...

SemBioSys announces senior management changes

... essential in helping us bring our plant-produced insulin forward into clinical trials and to initiate the negotiations now underway for our insulin and Apo AI candidates." James Szarko joined ... profit and non-profit sectors. "We believe with insulin and Apo AI that we have only begun to exploit the ...

InteKrin Therapeutics to Present at the 27th Annual JP Morgan Healthcare Conference on Tuesday, January 13

... side effects. INT131 is a next-generation insulin sensitizer that addresses insulin resistance, a ... type 2 diabetes. Treating and improving insulin sensitivity in diabetic patients by activating ... and is ideally positioned to safely reduce insulin resistance, addressing an important unmet medical ...

SemBioSys receives US$2.5 million from option agreement with MannKind for plant-produced insulin

... proprietary plant-produced recombinant human insulin for use primarily in MannKind's ultra-rapid ... on March 31, 2009. About SBS Plant-Produced insulin SemBioSys' plant-produced insulin is ...

SemBioSys begins phase I/II trial of insulin produced in plant seeds

... a phase I/II clinical trial of its plant-produced insulin with the first injection of its drug in humans. ... healthy volunteers in a three-arm study (SBS-1000 insulin and two commercial standards) to demonstrate the bioequivalence of safflower-produced insulin to ...

Video: Insulet Unveils Video Contest for OmniPod Users

... invited to create a short video to tell how using insulin pump therapy with the easy-to-use, tubing-free ... . About the OmniPod insulin Management System Cleared by the Food & Drug Administration (FDA) in January 2005, the OmniPod insulin Management System offers people living ...

Halozyme Therapeutics Reports 2008 Third Quarter Financial Results

... I am pleased with the initiation of our Phase 2 insulin clinical trial. The study will test our ... and Scientific Achievements -- A Phase 2 insulin clinical trial has been initiated in Type ... of a standardized liquid meal challenge and insulin pharmacokinetics after administration of each of ...

ConjuChem Provides Development Update

... achieve our objective of a more peakless basal insulin with a longer duration of activity." Results of ... About PC-Insulin PC-Insulin is a basal insulin with potential use in patients with either Type I ... is being developed to have advantages over basal insulin therapies that may show clinically ...

FDA Approves Additional Indication for Norditropin(R) for Small for Gestational Age (SGA) in Children

... cortisone acetate, thyroid hormone, insulin and/or oral diabetes medicines, drugs metabolized ... or thyroid hormone. If you are treated with insulin and/or oral diabetes medicines, the dose of your ... the most advanced products within the area of insulin delivery systems. In addition to diabetes care, ...

Halozyme Therapeutics Begins Phase 2 Clinical Trial of Insulin With rHuPH20 in Type 1 Diabetic Patients

... co-formulations with Humulin(R) R (regular insulin human injection) and with Humalog(R) (insulin ... of a standardized liquid meal challenge and insulin pharmacokinetics (PK) after administration of ... have achieved our goal of advancing our Phase 2 insulin program into the clinic before the end of the ...

Lilly Announces Launch of Color Differentiation System for Humalog(R) and Humulin(R) U-100 Insulin Products in the United States

... of a color differentiation system for U-100 insulin products marketed in the United States, ... [rDNA origin]) and Humulin(R) (regular insulin human injection, USP [rDNA origin)]). The Lilly ... the introduction of bar coding of packaging and insulin vials instituted in the U.S. by Lilly in 2004. ...

Nomad Bioscience: New Plant Biotechnology Company Founded to Focus on Biomaterials and Biopharmaceuticals

... product, Insulin, targets the US$7.5 billion insulin market. NOMAD's insulin will provide an economical alternative to commercially available insulin to better serve developing nations and meet ...

Halozyme Therapeutics Appoints Head of Endocrinology Clinical Development

... immediately add value to the advancement of our insulin and bisphosphonate programs," said Jonathan ... was the sole physician on the Lilly inhaled insulin development effort and the AIR(R) Insulin team. ... is how he became aware of Halozyme's proprietary insulin program and its recombinant human hyaluronidase ...

MannKind Unveils Proposed Trade Name at Dedication of Danbury Manufacturing Facility

... use AFRESA as the trade name for its Technosphere insulin System. AFRESA (pronounced uh-FRESS-uh) was ... care for prandial insulin needs, a rapid acting insulin analog. Later this Fall, we will report ... upon contact with the lung surface, releasing insulin monomers that rapidly enter the bloodstream. As ...

SemBioSys eligible to proceed with Phase I/II plant-produced insulin trial after submission of IND

... Phase I/II human clinical trial of plant-produced insulin now that the 30-day review period of ... intends to conduct the Phase I/II insulin trial in Europe. Prior to proceeding with the ... "The company continues to achieve its insulin development milestones on time. Our recent ...

Sanofi Aventis : New Study Results Support the "Basal Plus" Strategy With LANTUS(R) and APIDRA(R) to Improve Blood Sugar Control in Patients With Type 2 Diabetes

... Meeting demonstrating that the "basal plus" insulin strategy with LANTUS(R) (insulin glargine ... In the ELEONOR (Optimising basal plus insulin therapy in type 2 diabetes by telecare assistance ... blood glucose) and OPAL (Adding a single dose of insulin glulisine at breakfast or main meal to ...

Oramed Pharmaceuticals Partners With ETI Karle Clinical to Conduct Phase 2B Trials on Its Oral Insulin Capsule, ORMD 0801

... to conduct Phase 2B clinical trials on its oral insulin capsules. The study is intended to evaluate the ... and efficacy of ORMD 0801, Oramed's oral insulin capsule, on diabetic type 2 patients. It is ... patented flagship product, an orally ingestible insulin capsule currently in phase 2 clinical trials. ...

Insulet Appoints Bill Arthur as Vice President of Business Development

... and world-wide marketing of the company's insulin pump infusion set disposables. Previously, ... where he helped drive annual sales of insulin infusion pumps from $6 million to over $294 ... to expand the use of continuous subcutaneous insulin infusion (CSII) therapy among people with ...

British School Kids With Diabetes Gain First Time Freedom From Injections With New Insulin Pump Guidelines

... control for their condition, by greater access to insulin pump therapy. The new recommendations finally ... new guidelines that recommend greater access to insulin pump therapy to manage Type 1 diabetes, ... young people, with pumps replacing traditional insulin injections which have been shown to interrupt the ...

ReceptorBio Announces Diabetes License Agreement With Telik

... Pre-clinical testing has indicated that these insulin receptor activators, as single agents, lower ... at the dose levels examined. This synergy with insulin suggests the compounds could potentially be ... other anti-diabetic agents including insulin. The insulin receptor activating activity of these compounds ...

Insulet Reports Second Quarter 2008 Results

... The studies are utilizing the OmniPod as the insulin delivery device along with a model-predictive, ... titled "Clinical Experience with a Tubeless insulin Pump System," concluding that the OmniPod insulin Management System was safe and effective in ...

Halozyme Therapeutics Reports 2008 Second Quarter Financial Results

... results showed faster absorption and onset for insulin when co-administered with our PH20 enzyme, a ... enzyme (rHuPH20) with Humulin R(R) (regular insulin human) or Humalog(R) (insulin lispro) yielded ... mimicked physiologic prandial (mealtime) insulin release and activity than Humulin R or ...

SemBioSys announces second quarter 2008 financial and operational results

... Canadian Biotechnology Company hits key insulin and Apo AI(Milano) milestones TSX symbol: ... and operational results. Highlights insulin Program - Submitted an Investigational New Drug Application (IND) for safflower-produced insulin to the U.S. Food and Drug Administration ...

SemBioSys submits IND for safflower-produced insulin to U.S. FDA

... Submission demonstrates progress of plant-derived insulin program scheduled to enter the clinic later ... for safflower-produced recombinant human insulin to the United States Food and Drug Administration ... and structural analysis of safflower-produced insulin to a reference standard, results from 28-day ...

Telik Announces Publication of Diabetes Research in Bioorganic & Medicinal Chemistry Letters

... The compounds developed activate the insulin receptor and may have the potential to be an ... been actively sought after since the discovery of insulin in the 1920s by Banting and Best, and could ... of compounds that are capable of activating the insulin receptor and were also shown to increase glucose ...

Oramed Pharmaceuticals to Present Oral Insulin Trial Results at ADA Conference (June 6-10, San Francisco)

... (PK) and Pharmacodynamics (PD) of Oral insulin in Healthy Subjects, at the upcoming 68th Annual ... highlighting the successful results from its oral insulin trials on healthy volunteers. The abstract will ... and Pharmacodynamics of Alternate insulin Delivery Systems," on Saturday, June 7, 2008 from ...

Amylin Pharmaceuticals to Present Promising Data From Diabetes and Obesity Programs at ADA 2008

... 4. Oral Late Breaker: "Pramlintide or Mealtime insulin Added to Basal insulin Treatment in Patients with Type 2 Diabetes" will ... destroyed, resulting in reduced secretion of both insulin and amylin after meals. The use of SYMLIN ...
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