Insertion in Biological Technology

Junying Yu, Leading Stem Cell Researcher, Joins Cellular Dynamics International

... be reprogrammed to a stem cell state through the insertion of four genes. iPS cells are similar to human ... over the potential risks associated with the insertion of foreign DNA into the cell's genome. For example, insertion mutations could affect the biology of the cell or ...

STAAR Surgical Receives FDA Clearance for the Epiphany(TM) Injector System

... of the Epiphany will usher in a new era of insertion devices for the company and pave the way for the ... offers the flexibility of either twist or push insertion techniques - a unique feature of STAAR's IOL ... Epiphany provides for effortless yet controlled insertion through a 2.8mm incision and, being a single use ...

Intarcia Therapeutics, Inc. Presents ITCA 650 Phase 1b Study Results as a Late-Breaker at the American Diabetes Association 69th Scientific Sessions

... for a 28 day treatment duration via a single insertion of ITCA 650. Fasting & ... for the full course of treatment with a single insertion of the ITCA 650 on day 1 and removal on day 29. ... allows for steady state drug delivery upon insertion and near immediate withdrawal of therapy to ...

The Pittsburgh Life Sciences Greenhouse Starts 2009 With Investment Momentum

... develops and manufactures sterile catheter insertion systems that address catheter related blood ... field to help prevent contamination during insertion -- potentially removing the need for an external ... proprietary Flexicath features to facilitate the insertion procedure. NeuroInterventional ...

Scientists fix bugs in our understanding of evolution

... between two sequences is a deletion in one or an insertion in the other sequence. For correct alignment of ... and chimp and can't tell if a deletion or an insertion happened. To solve this our tool automatically ... show the same gap as the chimp, this suggests an insertion in humans." Findings achieved with the new ...

Dow AgroSciences, Sangamo BioSciences Announce the Achievement of Key Milestones in Plant Agriculture Collaboration

... in a rapid, single-step process. The precise insertion of the gene into the targeted ... value and versatility of targeted transgene insertion into crops. Sangamo's ZFP transcription factor ... combinations or stacks of multiple traits and the insertion of new traits could address increasing demand for ...

Patton Medical Devices Partners With Unomedical to Develop and Market the i-port Advance(TM) Injection Port for People Taking Multiple Daily Injections

... i-port(R) , will also provide improved features which may help to reduce insertion pain and enhance the user experience. "We are excited about working ... may help alleviate the potential for error from an improper manual insertion while providing the key benefit of having a simple way to deliver ...

Intarcia Therapeutics, Inc. Announces Acceptance of ITCA 650 Phase 1b Study for Late-Breaker Presentation at the American Diabetes Association 69th Scientific Sessions

... phase 1 trial is administered for the full course of therapy with a single insertion of the DUROS device on day 1 and removal on day 29. Results of the phase 1 ... albumin fusions, DUROS delivery allows for steady state drug delivery upon insertion and near immediate withdrawal of therapy to manage side effects, if ...

Medical Simulation Corporation to Introduce Central Line Management Program at the National Teaching Institute and Critical Care Exposition

... Program brings together the best practices for central venous catheter insertion and management into a comprehensive program that increases the competence ... together national guidelines for CLABSI prevention and safe central line insertion practices in a dynamic and hands-on training format. Patient care ...

Dow AgroSciences Announces Early Exercise of Option for Commercial License With Sangamo BioSciences for Plants

... utility of ZFP nucleases for precision gene modification and targeted gene insertion in plants. These technologies have the potential to play a major role in ... generation of combinations or stacks of multiple traits and the insertion of new traits could address increasing demand for crops for food and ...

CyberKnife Prostate Cancer Planning Study Published in Leading Radiation Oncology Journal

... clinical evidence supporting its usage. Nevertheless, the required insertion of multiple catheters into the prostate, where they remain for the ... used in the treatment of prostate cancer. The procedure involves the insertion of catheters into the prostate gland, and then the delivery of a series of ...

Angiotech Pharmaceuticals, Inc. announces financial results for the second quarter ended June 30, 2009

... include a unique filter design that may reduce the potential for filter migration after implantation, thereby making the product safer for patients, insertion potential through either the femoral or jugular route, which may make the product easier for a physician to use, and the use of non-thrombogenic ...

EMcision Announces 510(k) Clearance of the Habib EndoHPB, its Novel Bipolar RF Device for the Palliation of Biliary and Pancreatic Tumours

... sludge or by tumour pressure narrowing the stent lumen, necessitating regular changing of the stent. Use of the Habib™ EndoHPB prior to stent insertion improves the stent patency by delaying tumour growth. 2) Clearance of obstructed metal stents: Self-expanding mesh metal stents (SEMS), which ...

VerteLoc™ Tops 500 Surgical Procedures, VGI Announces VerteLX™ and Seeks Potential Investors for Growth

... difficult to use inter-operatively. VGI will introduce a system that utilizes just a few small instruments for the lateral surgical approach and insertion of a unique biomechanically superior implant." The VerteLX™ implant is like nothing ever seen previously in the spine market. VGI ...

Quest Diagnostics to Present Genomic Studies Related to New Testing Techniques for Leukemia and Prostate Cancer at 2009 ASCO Meeting

... percent of patients with CML who are resistant to treatment with imatinib exhibited the presence of alternatively spliced BCR-ABL1 mRNA with a 35-bp insertion (BCR-ABL135INS). The scientists also determined that imatinib, when combined with nilotinib or homoharringtonine (HHT), showed strong synergy, ...

Dow AgroSciences Confirms Efficacy of Zinc Finger Nucleases for Precise Genome Modification in Maize

... (PRWEB) April 29, 2009 - Scientists at Dow AgroSciences LLC, a wholly owned subsidiary of The Dow Chemical Company (NYSE:DOW), have demonstrated insertion of a gene for a herbicide-tolerant trait to a specific, pre-determined location in the maize genome confirming that precise modification is practical ...

Chromosome breakpoints contribute to genetic variation

... or it has to be of some benefit." Evolutionary biologists have historically focused on small changes in the genome such as point mutations or the insertion of viral genes that sometimes lead to the development of new forms, Lewin said. "But by overlooking the importance of chromosome rearrangements, ...

Fate Therapeutics and Stemgent Launch Catalyst: A Unique Industry Program for First Access to the Most Advanced Induced Pluripotent Stem Cell Technology

... cell therapies. Previously, iPS cell generation required the delivery of genetic material through viruses or plasmids, which carry risks from insertion and are time-consuming, inefficient methods. Now, in collaboration with Dr. Ding, Fate Therapeutics and Stemgent have developed small molecules and ...

Ancient diatoms lead to new technology for solar energy

... the interaction between photons and the dye to promote the conversion of light to electricity, and improve energy production in the process. The insertion of nanoscale tinanium oxide layers into the diatom shell has been reported in ACS Nano , a publication of the American Chemical Society, and the ...

Trusted LASIK Surgeons Welcomes Leading Laser Expert and Inventor Jon Dishler, M.D., to Its Unique LASIK Eye Surgeon Directory for Consumers

... to develop an FDA approved Excimer laser. His inventions include the Dishler Excimer Laser, the Excimer Beam Profiler, the Dishler LASIK Cannula, an insertion system for corneal implants, and a surgical visual feedback and eye fixation method and apparatus. Dr. Dishler has written over 10 peer-reviewed ...

Hebrew University scientist develop technique for eliminating reblockage of arteries

... Jerusalem, March 9, 2009 An easily implementable technique to avoid reblockage of arteries that have been cleared through angioplasty and stent insertion has been developed by researchers led by Prof. Boris Rubinsky of the Hebrew University of Jerusalem. Angioplasty is the "gold-standard" ...

AcroMetrix Announces the Release of OptiQuant-S Hepatitis C Virus (HCV) Panel

... a second generation viral RNA material which behaves very similar to enveloped mammalian RNA viruses like HCV or HIV. This new technology allows insertion of synthetic sequences into a mammalian RNA virus which were shown to be stable in replication and capable of forming infectious RNase resistant ...

Historic Seed Delivery Made in Illinois for First New Soybean Varieties With the Greater Yield Potential of Roundup Ready 2 Yield(TM)

... dependable weed control and crop safety as original Roundup Ready soybeans, but with higher yield potential resulting from advanced gene mapping and insertion technology. The technology provides higher yields by producing more beans per pod on the plant. Roundup Ready 2 Yield soybeans are the next ...

Heinlein Trust and SpaceX Announce Competition to Promote Research Innovation in Zero Gravity

... ten. With the Falcon 1 and Falcon 9 vehicles, SpaceX offers highly reliable/cost-efficient light, medium and heavy lift capabilities for spacecraft insertion into any orbital altitude and inclination. In addition, the Dragon spacecraft provides Earth to LEO transport of pressurized and unpressurized ...

Technique for Creating Authentic Rat Embryonic Stem Cells Published in Cell

... of response or different response profile to drugs compared with non-engineered animals can provide information on drug efficacy. Alternatively, the insertion of genes such as those involved in drug metabolism in the human liver means that knock-in models can provide information on drug safety & ...

Video: Allergan Announces U.S. Food and Drug Administration (FDA) Approval of Latisse(TM) -- First and Only Treatment Approved by the FDA for Hypotrichosis of Eyelashes

... cervical dystonia patients with all botulinum toxins. In these patients, there are reports of rare cases of dysphagia severe enough to warrant the insertion of a gastric feeding tube. Precautions Patients or caregivers should be advised to seek immediate medical attention if swallowing, speech, ...

Top LASIK and Refractive Experts in Trusted LASIK Surgeons Directory Present Research and Educate Their Peers at Annual AAO Meeting in Atlanta

... Group OMIG), which includes many of the world's leading specialists in ocular infections, entitled "Culture-positive endophthalmitis after insertion of the Staar Intraocular Collamer Lens". This was the FIRST such case to be reported in the United States since the introduction of this new ...

CAS Registers 40 Millionth Substance in CAS REGISTRY(SM)

... findings on November 21, 2008. Titled "Intramolecular Huisgen-Type Cyclization of Platinum-Bound Pyrylium Ions with Alkenes and Subsequent insertion into a Benzylic C-H Bond," the article describes a novel method for the synthesis of polycyclic substances with "a central seven-membered ...

Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on The Medical House PLC

... is intended to offer patients an easier, safer, and more convenient self-injection method. The ASI(TM) autoinjector is entirely automated-from needle insertion and medication injection to needle withdrawal and full retraction back into the device. When the shot is completed, the entire unit is disposable. ...

Sangamo BioSciences Reports Third Quarter 2008 Financial Results

... service for developing ZFNs for specific gene targets, the CompoZr ZFN platform will eventually include ZFN-based kits for targeted transgene insertion and a catalog of off-the-shelf reagents for commonly studied gene targets, gene families, and pathways. For more information on ...

One-Year Data Show Golimumab Improved Signs and Symptoms In Patients with Psoriatic Arthritis In Phase 3 Study

... though the changes were not statistically significant with the 50 mg dose. Enthesitis, an inflammation of a tendon, ligament or joint capsule insertion to the bone, and dactylitis, a swelling of digits in the hands or feet, are estimated to affect more than one-third of people with psoriatic ...

New Opportunities in X-Ray Based Surgical Navigation With Ziehm NaviPort 3D

... we are offering our customers an advanced solution for more efficiency in the operating room, a lower x-ray exposure dose and the more precise insertion of implants. Surgeons and patients world-wide will benefit from the integration of our two technologies", says Martin Herzmann, Director Global ...

Sigma-Aldrich Launches Breakthrough Genome-Editing Tools

... service for developing ZFNs for specific gene targets, the CompoZr ZFN platform will eventually include ZFN-based kits for targeted transgene insertion and a catalog of off-the-shelf reagents for commonly studied gene targets, gene families, and pathways. Applications for Sigma's new platform ...

Intact Medical Corporation's Intact(R) Excise XL Receives 510(K) Marketing Clearance from the FDA

... the product to physicians in the fourth quarter of this year. As with the Intact (R) BLES, the Intact (R) Excise XL procedure involves the insertion of a slender wand through a small incision in the breast to remove an intact sample of suspicious tissue for histopathologic analysis. The procedure ...

RADI Medical Systems Launches Next Generation PressureWire(R) Certus

... for physicians. The new large entry funnel allows for fast and easy wire reconnection into the proximal connector, while also exhibiting less insertion friction. In addition, the new locking cap provides positive reinforcement when the wire and the connector are locked in place via a user intuitive ...

Anesiva Launches Needle-Free Zingo(TM) to Reduce Pain from IV Starts and Blood Draws in Children

... line placements and blood draws in children three to 18 years of age. Zingo works quickly, within one to three minutes, to relieve pain at the needle insertion site. "Zingo is the first easy-to-administer, fast-acting local anesthetic that could lead to a paradigm shift in the approach to venous ...

New Liko Multiple Purpose Lifting Straps Facilitate Patient Care Tasks

... use across various departments. In burn units, the Multi-Strap Narrow can suspend a limb with limited skin contact. For the initial insertion or -reinsertion of a catheter for a patient of size, one Multi-Strap Ultra can help support each leg and eliminate the need for additional ...

Abbott Launches Next-Generation StarClose(R) SE Vascular Closure System

... procedure commonly used to evaluate or treat certain types of disease in vessels of the heart and other parts of the body. The procedure involves the insertion of a flexible tube, called a catheter, into the femoral artery in the leg. The physician will use the catheter to observe the condition of the ...

StemCor Systems, Inc. Awarded NIH SBIR Grant for Bone Marrow Aspiration Platform

... manner, in the outpatient setting, and without general anesthesia. This is in contrast to the current practice of bone marrow aspiration through the insertion of a large gauge needle into multiple sites of the iliac crest of the hip, which usually requires general anesthesia, an operating room, and ...

Angiotech showcases its Hemostream(TM) Dialysis Catheter at the Society of Interventional Radiology (SIR) Annual Meeting

... Ensures functional flow rates in the event that two lumens become completely occluded. - Transition: Provides atraumatic over-the-wire insertion without the need for a peel-away sheath. - 360 degree Arterial Tip Configuration: Eliminates catheter "side- walling" against vessel. ...