infections

Luminol-enhanced Assay for Superoxide Anion (O2 face="Symbol" )

...tients who have altered oxidative means to control infections and biochemical research involving the analysis of leukocyte signal transduction pathwayscomponents comprising NADPH oxidase and requirements of the respiratory burst. In addition, the assay may be used to study the generation of oxygen radicals in A...

HSVision Molecular Beacon Detection Module Rapidly Detects Herpes Simplex Virus DNA

...ial andgenital surfaces. However, more serious HSV infections can also involve thecentral nervous system and viscera, particularly in newborns andimmunocompromised patients, where they are often life threatening. There are twoHSV subtypes, HSV-1 and HSV-2, 2 which are serologically andgenetically distinct. HSV...

Normalizing cDNA libraries using the EppendorfThermomixer

...a cell to exogenous influences such as viral infections or medical treatment. To allow unstable mRNA to be examined more thoroughly, it is converted to cDNA. If all isolated mRNAs of a cell are converted to cDNA, the result is referred to as a "cDNA library." The synthesis of such a...

The QIAGEN Guide to Animal Cell Culture

...ely evaluated for contamination. Mycoplasmal infections are one of the more common and difficult-to-detect infections; their detection and eradication are described in further detail below. Mycoplasmal infection detection Mycoplasmas are small, slow-growing...

Microfluidic analysis of multiplex PCR products for the genotyping of Helicobacter pylori

...dwith H. pylori. But despite thehigh prevalence of infections onlya minority of infected individualswill develop gastric carcinoma orMALT lymphoma. Therefore, it isessential to identify factors thatmight determine the possiblesequelae of the H. pylori infection,such as host and environmentalfactors and bacteria...

Preparative SDS-PAGE Electrophoresis of a Recombinant Epstein-Barr Virus Encoded Protein and Its Application in Serodiagnostic Test Systems, Rev C

... diagnosis as well as the follow-up of severe infections are of vital importance. Previous experiments by our group led to identification of a 23 kD viral protein recognized by antibodies from more than 96% of EBV carriers tested. After identification of the coding region, the corres...

Detection of nitrofurane metabolites in food with HPLC/MS/MS

...s they were used for treatment of gastrointestinal infections in cattle and poultry. Due to its proven mutagenic and carcinigenic effect, nitrofuranes (except for furazolidone) was prohibited in 1993 in the European Union (VO (EWG) No. 2901/93). Furazolidone was prohibited in 1995 in the European animal breedin...

High sensitivity quantitation of metabolites of nitrofuran antibiotics in animal tissue using LC/MS/MS

...d additives for the treatment of gastrointerstinal infections in cattle, pigs, and poultry. Due to mutagenic and genotoxicity, these antibiotics are now banned in food-producing animals. The contamination may not only occur from deliberate and direct misuse of the drugs, but also from contaminated feed and envi...

Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods

...sible for much of the pathology in servere infections like sepsis and septic shock. LPS causes a very strong stimulation of different cells of the immune system, such as monocytes, macrophages, B cells, polymorphic nuclear- and endothelial vascular cells. LPS is biological...

Medical College team creates website for tracking flu

...netics data specialist Jack Littrel; and pediatric infections disease lab supervisor Andrea J. Kraft, M.S. Bi...nd IX International Symposium on Respiratory viral infections in Hong Kong. Henrickson said the website was well received at those gatherings, and he believes it...

ConjuGon raises $3.3 million to fund clinical trials

...pital for clinical trials of its treatment for the infections of large wounds, and to fund the development and testing of its core technology - therapies for the treatment of antibiotic-resistant bacterial infections. In recent years, antibiotic resistance has created a crisis in medicine, and it is responsib...

Nerites raises $1 million to improve medical tech

... evaluated in reducing the likelihood of bacterial infections at the site of medical implants. In addition to the testing, CEO and President Thomas J. Mozer said the funding has enabled Nerites to build corporate relationships, develop scientific partnerships, and begin working with clinicians that use its pro...

Technology played key role in E. coli alerts

...Milwaukee . "Occasional, sporadic cases of E. coli infections happen all the time, and it's not possible to chas...enetic fingerprints of these organisms to identify infections by identical pathogens in disparate geographic areas," explained Herb Bostrom, director of the Wisco...

UW finds new path to anti-cancer agents

...hat an alarming 59 percent of skin and soft tissue infections in emergency rooms nationwide were resistant to antibiotics now in use. The new technique, according to Thorson, will play a prominent role in the new UW-Madison National Cooperative Drug Discovery Group, a consortium of UW-Madison scientists seekin...

Human stem cells grown free of animal contamination

...or stem-cell treatments with lower risk of causing infections because of animal-cell contamination. Growing stem cells in the lab requires a careful mix of nutrients, hormones and other chemicals. Previously, "feeder" cells obtained from mouse embryos were used to grow many of the currently available human stem...

This wheelchair will save lives

...velop pressure ulcers, which can lead to secondary infections such as septicemia. In certain cases, septicemia can lead to septic shock, which can cause cardiac arrest and even death. An infected pressure sore, for example, led to Christopher Reeves death this October. The best way to prevent this downward sp...

ConjuGon lands $1 million angel investment

...atments. ConjuGon develops remedies for bacterial infections that have become resistent to standard drugs. In general, the funds are to test our therapeutic capabilities, said Sal Braico, chief operating officer of ConjuGon. ConjuGon has been enjoying a string of success in obtaining funding. Its total raise...

ConjuGon receives $500,000 to battle bacteria

...prevent or treat catheter-associated urinary tract infections and other kinds of resistant infections." ConjuGons first therapeutic is expected to be in pre-clinical testing next year, Braico added. SBIR grants are frequently peer-reviewed and are designed to prove the technological feasibility and credibili...