Infection in Biological Technology

First genetically engineered malaria vaccine to enter human trials

... Professor Alan Cowman, head of the institute's infection and Immunity division, said in developing the ... the malaria parasite is halted during its liver infection phase, preventing it from spreading to the blood ... provide protection against subsequent malaria infection in animal models and humans in developing the ...

Novavax Announces Selection of a Respiratory Syncytial Virus Vaccine Candidate for Advanced Preclinical Studies

... and cell mediated immune responses to prevent infection of the respiratory tract and attack respiratory ... dose (1.0 mcg) of RSV-F vaccine prevented RSV infection in the lungs of these mice. However, protection from RSV infection was not observed in unvaccinated mice. Based on ...

MacroGenics Announces the Initiation of a Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Monoclonal Antibody MGAWN1 in Subjects with Suspected Central Nervous System Infection Due to West Nile Virus

... individuals with suspected central nervous system infection due to West Nile Virus (WNV). MacroGenics, a ... than 28,000 cases of confirmed symptomatic WNV infection in the U.S., which include more than 11,000 WNND ... than 1,100 deaths. In 2008, 1,356 cases of WNV infection were reported to the Centers for Disease Control ...

Innocoll Announces Provisional Findings From Its Three Phase 2 Clinical Trials Investigating CollaRx(R) GENTAMICIN TOPICAL for the Treatment and Prevention of Diabetic Foot Infections

... TOPICAL for the treatment and prevention of infection in diabetic foot ulcers. Chronic ulcerations ... systemically acting antibiotics less effective. infection can also spread to the bone (osteomyelitis), ... the product for the prevention of diabetic ulcer infection versus placebo control (collagen sponge) in a ...

Three Rivers Announces Positive Results from Phase 3 DIRECT Trial of Once-Daily INFERGEN(R) with Ribavirin in Hepatitis C Virus Treatment Failures

... is indicated for the treatment of chronic HCV infection in patients 18 years of age or older with ... Hepatitis C is a liver disease that results from infection with the hepatitis C virus. It can range in ... "acute" or "chronic." Acute hepatitis C virus infection is a short-term illness that occurs within the ...

Clostridium difficile Infection: Strategic Approaches for Better Outcomes

... the epidemiology of Clostridium difficile infection (CDI) has been changing. This trend may be the result of antimicrobial use, infection control practices, or other factors. It is ... gastroenterology, microbiology, epidemiology, and infection control. Healthcare professionals can visit ...

Study Finds Noninvasive Blood Test for Liver Fibrosis May Alleviate Need for Liver Biopsies for Some Patients with Chronic Hepatitis C

... in a subset of chronic HCV patients." infection with HCV most often results in chronic HCV, a ... liver cirrhosis or cancer. Physicians manage HCV infection based on assessments of the degree of a patient's ... hundred and ninety one patients with chronic HCV infection undergoing liver biopsy were enrolled from the ...

Optimer Pharmaceuticals Announces Lower Recurrence Rates for Fidaxomicin Versus Vancocin(R) in Subgroup Analyses from Its Phase 3 Study for the Treatment of CDI

... in patients with Clostridium difficile infection (CDI) were presented today by clinical ... the Division of Infectious Diseases, Chair of the infection Prevention and Control Unit at Jewish General ... About Clostridium Difficile infection CDI has become a growing problem in hospitals, ...

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

... be discontinued if a patient develops a serious infection or sepsis. Reported infections include: ... use and during therapy. Treatment for latent infection should be initiated prior to CIMZIA use. ... for the development of signs and symptoms of infection during and after treatment with CIMZIA, including ...

PharmAthene Presents Data for SparVax(TM), a Novel Vaccine for the Prevention and Treatment of Anthrax Infection, at the 12th Annual Conference on Vaccine Research

... "primed" the immune system to respond to natural infection by producing antibody due to immunologic memory.) ... anthrax. Initial symptoms of inhalation anthrax infection may resemble a common cold. After several days, ... for the prevention and treatment of anthrax infection Protexia(R) - a novel bioscavenger for ...

Cepheid Announces Symposium Speakers and Program Highlights for 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)

... the symposium where leading microbiology and infection control specialists will present data on the ... Will Community MRSA and C. difficile Change infection Control in Hospitals? ... all elective admissions and other developments in infection control across Europe," said Dr. David Persing, ....

Health Canada Approves SIMPONI(TM) (golimumab) for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... the use of SIMPONI in patients with a chronic infection or a history of recurrent infection. Patients should be monitored for signs and symptoms of infection while on or after treatment with SIMPONI. If a patient develops a serious infection or sepsis, SIMPONI therapy should ....

Roche to Introduce New LightCycler(R) MRSA Advanced Test in the EU

... Molecular Diagnostics. "This new test will aid infection control programs, and ultimately result in better ... in the past few years, feeding the pipeline of infection in hospitals, and underscoring the need for comprehensive infection control programs. Dr. Reinhard Frodl, ...

Aethlon Medical Announces Data Supported Strategy to Increase Hepatitis-C (HCV) Cure Rates

... of care and other candidate therapies. HCV infection is considered cured when SVR extends beyond six ... Hemopurifier(R) inhibited the progression of HCV infection in ESRD patients when included during dialysis ... are treated each year. Although chronic HCV infection varies greatly in its course and outcomes, 70% of ...

NOVAVAX Announces Preclinical Study Results for a Respiratory Syncytial Virus ('RSV') Vaccine Candidate Directed Against the Fusion (F) Protein

... against RSV, which are important for preventing infection and lower respiratory illness, were highest in ... identified cause of lower respiratory tract infection in infants and young children with repeated ... patients are hospitalized annually due to RSV infection in the US and major European countries. In the ...

PharmAthene Presents Data for SparVax(TM) and Valortim(R), a Novel Vaccine and Anti-Toxin for the Prevention and Treatment of Anthrax Infection at the 7th Annual ASM Biodefense Meeting

... to provide significant protection against anthrax infection when administered prophylactically post-exposure ... anthrax. Initial symptoms of inhalation anthrax infection may resemble a common cold. After several days, ... for the prevention and treatment of anthrax infection Protexia(R) - a novel bioscavenger for ...

Sangamo BioSciences Initiates Phase 1 Trial of CCR5-ZFP Therapeutic to Treat HIV/AIDS

... has been shown in an animal model of HIV infection to lead to an increase in CD4+ T-cell counts, a ... make a patient's T-cells permanently resistant to infection by CCR5-specific strains of HIV and we are very ... "The ability to protect immune cells from infection with HIV and the expansion of CCR5-modified ...

bioMerieux Introduces Surveillance Tool to Fight Healthcare-Associated Infections

... solution provider of healthcare-associated infection (HAI) case management and surveillance software. ... automates the collection of data required by the infection control teams (ICT), providing real time alerts, ... company dedicated to improving efficiency within infection control teams, through providing innovative ...

DiFUSION Technologies Completes Successful Testing of Antimicrobial Spinal Implant

... DiFUSION's solution will not only improve infection ratios, it will also save the patient from ... a profound impact on lowering the devastating infection rates recently reported by the HHS' Centers for ... with antimicrobial coatings which do not fight infection past the first 48 hours. Our technology provides ...

New Biologic STELARA(TM) Receives Approval in Europe for Treatment of Moderate to Severe Plaque Psoriasis

... STELARA during an active infection. If a serious infection develops, monitor patients carefully and stop STELARA until the infection resolves. Patients should be evaluated for tuberculosis (TB) infection prior to initiating treatment with STELARA. ...

Tips from the journals of the American Society for Microbiology

... findings in the August 2008 issue of the journal infection and Immunity . Transmitted by infected fleas, ... avirulent Yersinia pseudotuberculosis strain. infection and Immunity, 76. 8: 3808-3816.) Oral ... Lactobacillus from Breast Milk May Treat Common infection in Lactating Mothers Oral administration of ...

ASP Announces Availability of EVOTECH(TM) Endoscope Cleaner and Reprocessor - First Commercially Available System to Eliminate Manual Cleaning of Endoscopes

... of how ASP is continually delivering innovative infection prevention solutions that meet our customers' ... record of designing and delivering innovative infection prevention solutions that dramatically raise the ... to simplify the process of buying and operating infection prevention products and services every day, for ...

Ultrasound Transducer Disinfection in Many Cases Insufficient

... Nanosonics is currently focused on developing infection control solutions for the global healthcare ... (1) Rutala WA, Weber DJ, Healthcare infection Control Practices Advisory Committee. Guideline ... . (2) Association for Professionals in infection Control and Epidemiology (APIC). Press release, ...

New Data Suggest CIMZIA(R) (Certolizumab Pegol) Active in Treating Moderate to Severe Crohn's Patients With Fistulizing Disease

... contents into other organs, or a life-threatening infection or abscess. These results focus on a ... percent and less than 1% respectively were due to infection or infestation; 2% and 4% respectively were due ... treatment of patients with latent tuberculosis infection reduces the risk of reactivation in patients ...

ANA598 Receives Fast Track Designation From the FDA for the Treatment of Chronic Hepatitis C Infection

... Clinical Need and Market Opportunity in HCV infection Chronic HCV infection is a serious public health concern affecting ... Cirrhosis of the liver resulting from chronic HCV infection is the leading indication for liver ...

Nephros Provides Corporate Update

... filtration products for therapeutic applications, infection control, and water purification, today provided ... U.S. Sales of DSU filters for institutional infection control Developed initial concepts for ... expansion of DSU product sales for institutional infection control and preparation for the anticipated ...

Mexican Department of Public Health to Launch Screening for Human Papillomavirus (HPV), Cause of Cervical Cancer

... for screening - including the HPV test. infection with the papillomavirus is very common. In fact, ... it causes any problems. However, in others, the infection lingers and can cause abnormal cells to form. ... that 80 percent of women will get an HPV infection at some point in their lives. However, in most ...

Tips from the journals of the American Society for Microbiology

... findings in the August 2008 issue of the journal infection and Immunity . Transmitted by infected fleas, ... avirulent Yersinia pseudotuberculosis strain. infection and Immunity, 76. 8: 3808-3816.) Oral ... Lactobacillus from Breast Milk May Treat Common infection in Lactating Mothers Oral administration of ...

Dorset County Hospital Enhances MRSA Surveillance Programme Through Rapid Patient Screening

... surgery Alison Tong, Director of Nursing and infection Prevention and Control, says, "We are always looking for new ways to further prevent infection and improve patient care. Xpert MRSA rapid ... by the bacteria, including blood poisoning, organ infection and lung infection. Owing to the risk carriers ...

Anadys Pharmaceuticals Commences Dosing ANA773 in Hepatitis C Patients

... Market Opportunity in HCV Infection Chronic HCV infection is a serious public health concern ... Cirrhosis of the liver resulting from chronic HCV infection is the leading indication for ... Most infected individuals are unaware of their infection status and the large majority of individuals who ...

Sangamo BioSciences Presents Data at ICAAC Demonstrating 'In Vivo' Protection Against HIV Infection by CCR5-ZFN Therapeutic

... Advantage of ZFN-Treated Immune Cells after HIV infection and Reduced Viral Loads WASHINGTON and ... T-cells can be made permanently resistant to HIV infection by treatment with zinc finger DNA-binding protein ... mutation were highly resistant to infection by HIV. Consequently, a variety of small molecule ...

Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R)

... modeling for therapeutic intervention in anthrax infection (in contrast to post-exposure prophylaxis) has ... a positive ECL were used to identify an active infection that required therapeutic intervention, and ... to provide significant protection against anthrax infection when administered prophylactically post-exposure ...

The Plasmodium vivax genome provides new routes and challenges in the global fight against malaria

... result of the research refers to the routes of infection of the parasite, as analysis of the genome ... complex life cycle. These alternative routes of infection have not been observed in previous research and ... form and, months or years later, when the primary infection has been overcome, can cause clinical relapses. ...

Cepheid Receives FDA Clearance for First Rapid On-Demand Molecular Diagnostic Test for MRSA and S. aureus

... from suspected skin and soft tissue infection swabs to determine if a patient is infected with ... makes it possible to accurately detect a staph infection before a patient is released, and it provides ... length of stay is 18 days following a MRSA infection and 9 days for a SA infection. Xpert MRSA/SA ...

Tips from the journals of the American Society for Microbiology

... findings in the August 2008 issue of the journal infection and Immunity . Transmitted by infected fleas, ... avirulent Yersinia pseudotuberculosis strain. infection and Immunity, 76. 8: 3808-3816.) Oral ... Lactobacillus from Breast Milk May Treat Common infection in Lactating Mothers Oral administration of ...

eGenomics Awarded First U.S. Patent Covering Rapid DNA Sequencing Technology Platform to Control Hospital-Acquired Infections

... algorithms. The platform allows hospital infection control teams to monitor in "real time" the ... problems. "The eGenomics platform will allow infection control teams to monitor and prevent potential ... It will allow us to focus our infection control efforts on the most critical areas," ...

GeoVax Labs, Inc. Announces Six Month Financial Results and Provides Operational Update

... vaccine (vaccine administered prior to infection with the HIV virus). In Phase 1 trials, ... to the primates to reduce the viral RNA infection levels to very low levels creating a non ... whether the vaccine could control the SIV infection during the absence of the drugs. Data from ...

U.S. Clinicians Indicate a Strong Need for New Tools to Combat Sepsis

... caused by the body's response to a severe infection of the blood and/or tissues, affects between 5 ... (PCT) -- a telltale sign of systemic bacterial infection -- recently received 510(k) clearance from the ... are frequently prescribed even before bacterial infection is confirmed. This could increase the development ...

Improved culture system for hepatitis C virus infection

... of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a ... culture system, which mimics the biology of HCV infection in humans. "This is the first efficient and ... more from liver cancer are attributed to HCV infection in the United States each year. The HCV life ...

Cepheid Signs Group Purchasing Contract with Novation, the Nation's Largest Healthcare Contracting Organization

... time, is a key component of a comprehensive infection control program," said Rob Koska, Cepheid's ... cause of Healthcare Acquired Infections (HAIs). infection rates have increased every year since 1970. Xpert ... Novation hospitals to implement more efficient infection control measures, leading to lower HAI rates and ...