genomics

QIAGEN Instrument Service insist on the best in service and support

...39 human cancer-related genes for functional genomics studies using RNA interference (RNAi). The Cancer siRNA Oligo Set Version 1.0 offers: A comprehensive set of genes - two siRNAs to each of 139 human cancerrelated genes and positive- and negativ...

Custom and library siRNA for efficient gene silencing

...nables targeted gene silencing in functional genomics studies. Now, QIAGEN offers a custom siRNA oligonucleotide synthesis service that includes a range of modifications and also library siRNAs directed against common target genes. QIAGEN siRNA Oligo Synthesis Service offers: ...

Custom and library siRNA for efficient gene silencing

...nables targeted gene silencing in functional genomics studies. Now, QIAGEN offers a custom siRNA oligonucleotide synthesis service that includes a range of modifications and also library siRNAs directed against common target genes. QIAGEN siRNA Oligo Synthesis Service offers: ...

Cancer siRNA Oligo Set Version 1.0

... of 139 human cancer-related genes for functional genomics research using RNAi. Cancer-related genes were chosen in collaboration with leading academic cancer researchers (see table below for a list of genes). Every siRNA has been designed using state-of-the-ar...

RNAi Gene Silencing System

...revolutionized the field of functional genomics by allowing targeted inhibition of gene expression using double-stranded RNA (dsRNA) that carries the same sequence as mRNA transcribed from the target gene. In mammalian cell systems, double-stranded siRNA oligos ...

WHOLE GENOME SEQUENCING

... Agencourt's sequencing team has over 75 years of genomics experience from organizations such as The ... our quality and past contributions to the genomics community by designating Agencourt as one of the Large Sequencing Centers to conduct genome ...

Microarray Target Purification Kit and the Microarray Target Synthesis Kit (T7)

...s make their way into different areas offunctional genomics research. Arrays provide immobilizedgene-specific sequences (probes) on differentsolid supports (e.g., nylon membranes, glass slides, orsilicon/ceramic chips) and are hybridized with labeledtargets that are copies of nucleic acids derived fromvarious...

RNA Interference and Gene Silencing: History and Overview

...mportantly, how can it be harnessed for functional genomics experiments? This article will briefly answe...d about RNAi's potential use as a functional genomics tool. Already RNAi has been used to ascertain the function of many genes in Drosophila , C. ...

RNA & cDNA Purification Using RNAClean

...nologies. Introduction As the genomics revolution moves from gene discovery to gene function analysis, techniques requiring RNA manipulation are becoming more prominent. Development of antisense RNA (aRNA) amplification technology has revolutionized gene expression...

Aurum Plasmid 96 Kit Tech Note, Rev A

...e plasmid DNA to glass membranes. However, genomics laboratories with automated fluorescence-based sequencing systems have created a demand for high-throughput plasmid purification in a 96-well format. Accordingly, high-throughput plasmid purification kits must take into accoun...

Amplification of genome-representative DNA from limited sources with GenomePlex WGA technology for use in genetic alterations studies

...ievement. The development of high-throughput genomics and DNA sequencing has provided researchers the ab...nd exact DNA sequences of many genomes. Functional genomics researchers use sequencing as an analysis tool for genotyping and microarray-based technologies. The...

Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma

...In addition, putative biomarkers identified from a genomics based discovery platform can also be included in this validation strategy as all that is required is the sequence of the protein. No peptide or protein standards are required for method development. High Quantitative Reproducibility: ...

Development of Radioligand Binding Assays for the Motilin Receptor Using ScreenReady Targets.

... Recent advances in combinatorial chemistry and genomics programs have led to an unprecedented increase in both the number of compounds and potential drug targets that can be screened. The development of automated liquid handling and microplate assay systems has helped to meet the demand for increased thro...

Protein Depletion for Plasma and Serum Proteomic Analysis

...dentifying disease- associated biomarkers: genomics and proteomics. In the genomics approach, genes that are associated with specific diseases or physiological processe...

NimbleGen to discontinue IPO after Roche's $272.5 million acquisition

... and Valium, acquired NimbleGen to gain entry into genomics research, which it considers a high-growth global ...ne in Roche's strategy to become a major player in genomics research. He called NimbleGen's array systems highly synergistic complements to Roche's portfolio of...

Who is minding the Innovation Gap?

...crete terms, while fundamental discoveries such as genomics and molecular medicine and related R&D spending grow exponentially, the number of novel drugs and products reaching the market continues to decline. Some call it the sparse pipeline problem, but that is only one manifestation - the tail end - of the ...

Personalized medicine and technology convergence

...uman Services. A number of measures to encourage genomics and biobanking research. Enhancement of genomics workforce training. An income tax credit for patients paying for genetic tests or the research re...

IPO-bound NimbleGen traveling in fast company

...r. Leroy Hood, a prominent molecular biologist and genomics researcher, joined NimbleGen's board of directors. Hood, who is co-founder and president of the Seattle-based Institute for Systems Biology , gained notoriety by helping to create a DNA sequencer to map the human genome. Hood, who will serve as ch...

Lucigen Corp. enters global licensing agreement

...s a way to expand its research product lines from genomics , the study of the genome, to proteomics , the la...s using the OverExpress cells with its single-cell genomics cloning technologies to produce new types of enzymes from rare microorganisms isolated from boiling ...

Genomics researcher Hood joins NimbleGen board

...r. Leroy Hood, a prominent molecular biologist and genomics researcher, has joined the board of directors of NimbleGen Systems , a Madison biotechnology firm. Hood, who is co-founder and president of the Seattle-based Institute for Systems Biology , will serve as chairman of NimbleGen's scientific advisory...

Biotech executive books a career flight that's closer to home

...us has held executive positions with Amersham , a genomics company that now is part of GE Healthcare , and Covance, Inc., in Madison. Pete Shagory, a partner in Baird Venture Partners, the U.S.-based venture capital arm of Baird Private Equity, said Fergus would reinforce Baird's focus on the life-scien...

UW scientist, former WiCell director found stem cell company

...w term in "metabolomics. The field, a companion to genomics and proteomics, is the study of metabolism in organisms, and it's the research focus of Cezar, who came to UW-Madison last year after working as a senior research scientist with Pfizer . The proprietors got to know each other as part of the stem c...

DNASTAR catches second wave of sequencing

...contributed to a somewhat underappreciated role in genomics - at least among the general public. "People insi...and he was involved in the founding of the Madison genomics firm NimbleGen . With reluctance, Blattner concedes that he is a serial entrepreneur, the kind tha...

Marshfield Clinic and UW combine to speed tech growth

...tive for specific individuals. It is essentially a genomics bank that will help tailor drugs and treatments to a person's specific genetic code. Merging might The UW System has about 200 researchers working on developing therapeutic molecules for various diseases, medical imaging technologies for diagnosi...

UW-Madison gets $333,000 for biofuels research

...ucts would build on DOE's strategic investments in genomics to promote the development of alternative energy sources. To develop a reliable energy source, he noted that farmers and ranchers "would need to grow biomass in large quantities," and the grants are designed to improve the efficiency with which bioma...

Prodesse joins forces with Invitrogen

...ession studies, biomarker analysis, and functional genomics experiments. The advantage of LUX, according to Invitrogen, is in its improved sensitivity and specificity over traditional methods of analysis, and its ability to examine multiple targets in one experiment. "Scientists in basic research and drug d...

GE Healthcare partners with genomics institute

...he alliance is designed to apply advanced cellular genomics technologies to accelerate research in translation...munity," Spyro Mousses, director of pharmaceutical genomics and cancer drug development for TGen, said in a statement. Mousses also said the imaging systems pr...

Doyle launches 2025 alternative energy plan

...hnologies. It cites the UW's capabilities in plant genomics and plant biochemistry, and calls for continued investments to strengthen that capacity. Doyle said that during his push to install more E85 pumps in gas stations across the state, he was stymied by "senseless action by the legislature to back away ...

The mushrooming of biotechnology in the U.S.

...ses. Arizona earmarked $90 million to attract a genomics research center in Phoenix (home of Arizona State University in nearby Tempe), and Tucson (University of Arizona) seems to be exploding in scientific and biotech activity, and has been a huge recipient of NASA research funding. Missouri is apparen...

Searle spirit lives on in Chicago as alumni celebrate at former home

..."wet labs" for biology, chemistry, toxicology, and genomics laboratory work; the state-of-the-art vivarium and toxicology center (J building) consisting of 133,000 square feet; the pilot manufacturing center (P building) containing both a GMP pilot solid dosage form manufacturing suite (tablets and capsu...

Seth Dobin heading up Marshfield's Mammalian Genotyping Service

... He plans to apply his experience in genetics and genomics research to problems of mental health and development of new genetic and genomics tools. Dobrin said he hopes to build on discoveries he made earlier in his career as well as discove...

Successful Wisconsin VC sets sights on data integration and mass storage

...rocedure can demand up to 750 MB. And then there's genomics information: the data generated to create just one optical map file can eat up to 1 terabyte of memory. As critical as storage is, of the three hot spots, data integration (for example, integrating widely disparate data at hospitals) is the hottest,...

Third Wave boosts numbers in latest report

... revenue decline in a once-lucrative revenue area, genomics research. The company is looking for a clinical re...d other product strategies, despite the hit to its genomics research revenue, Third Wave's strategy should put the company in a solid position going forward, ac...

Five seed-stage funding groups filling Midwest Life Science void

...tory is Third Wave Technologies, a publicly traded genomics diagnostics company in Madison with a current market cap of about $140 million. It has raised more than $82 million to date. Another difference between the Kegonsa Seed Fund, Venture Investors and IllinoisVENTURES is that the latter two groups have...

Life Sciences: Wisconsin- The Smart Choice

...ective for specific individuals. Its essentially a genomics bank that will help tailor drugs and treatments to a persons specific genetic code. The Blood Research Institute Tied to the Blood Center of Southeastern Wisconsin, this Milwaukee research center provides basic research in these areas: transfusio...

Bruker AXS launches new products at PITTCON 2004

... increasing interest in high-throughput structural genomics in both basic biosciences and drug discovery. That this is a high national priority is reflected in, for example, the recent announcement and the significant funding of the second phase of the NIH Protein Structure Initiative, said Roger Durst, Bruke...

Networking of Healthcare Information

...tive drug reactions could be identified. Clinical genomics can have an impact on drug studies and negative reactions, Taylor said. A successful trial would be targeted to people responsive to that therapy....

The Role of Engineering in Health Science and Technology

...otech Age. With the incredible rate of advance in genomics and proteomics, we stand on the threshold of a new era which holds the potential for personalized medicine and individualized health care that promises to be much more effective than todays technology. With the ability to detect disease much earlier...

Barriers Outlined for Wisconsins Biotech Growth

...mes Prudent, chief science officer with functional genomics company EraGen Biosciences , Madison, points to advances in bioscience development in China and the lack of a major pharmaceutical company in Wisconsin as stumbling blocks. If you ask what the difference is between Wisconsin and Nebraska, the answe...

Marshfield Clinic charges ahead in genetic research

... rushing to establish ways to implement functional genomics in the clinical world, Wilke said. The Right Mix Catherine McCarty, a molecular epidemiologist and director of the PMRC, said that two fields of knowledge now can be blended at the clinic in unprecedented ways to get a leg up on disease. Epidemi...

Whole Genomes From Microbes to Man

...(now GlaxoSmithKline) and led GW's UK genetics and genomics programs from 1993-1998. Prior to joining OpGen, h...rience in applying molecular biology, genetics and genomics to the discovery and development of human therapeutics and diagnostics. OpGen's has raised almost $...

ePrairie Uncovers 80 Biotech Companies in Illinois

...Genomics Chicago * Private Veterinary genomics 69 Proteintech Group Chicago * ...). There are four nanotech companies, four genomics companies, three companies involved in veterinary or plant science biotech, six companies in...

Molecular Cloning Systems Gets Distributor

... with Lucigen to leverage their unique single cell genomics technology will provide Agencourt with an innovati...rated into its current CloneSmart gene cloning and genomics products, PicoClone cloning services, and Single Cell Genomics technology for new product discovery....

Chipping Away at Drug Development

...ng research in breakthrough medical fields such as genomics and proteomics, two fields intimately tied to the medical breakthroughs that have helped to put UW-Madison squarely atop the medical research field. With its GenLink surfaces and surface chemistry products, GenTel is hoping to meet its basic chal...

Molecular Cloning Systems Gets Distributor

... with Lucigen to leverage their unique single cell genomics technology will provide Agencourt with an innovati...rated into its current CloneSmart gene cloning and genomics products, PicoClone cloning services, and Single Cell Genomics technology for new product discovery....