Genes in Biological Technology

Bacteria pack their own demise

... from the editorial board. It's in the genes For years, Nathalie De Jonge, Remy Loris and ... way of providing extra protection to important genes the toxin-antitoxin (T-A) system. These T-A genes are tucked in near ...

First genetically engineered malaria vaccine to enter human trials

... the vaccine the research team had deleted two key genes in the Plasmodium falciparum parasite which ... of malaria most deadly to humans. By removing the genes the malaria parasite is halted during its liver ... produce similar results in humans. "Although two genes have been deleted the parasite is still alive and ...

febit First to Offer Newly Published Mouse Genome on a Chip for DNA/RNA Detection and Enrichment

... enables up-to-date profiling and enrichment of genes and SNPs of interest using Gene Expression ... ncRNA analysis as well as targeted enrichment of genes for Next-Generation Sequencing (NGS). ... gaps, completes the list of protein-coding genes to a number of 20,210 and identifies 439 long, ...

Syngenta and Evogene to Collaborate on Soybean Nematode Resistance

... with Evogene, Ltd., focusing on identifying plant genes related to soybean nematode resistance. Under the ... receive exclusive licensing rights to candidate genes discovered by Evogene for use in soybean. ... trait discovery program, creating new sources of genes for biotech traits to strengthen our current ...

Israeli scientists show bacteria can plan ahead

... to lactose, and found that, in addition to the genes that enable it to digest lactose, the gene ... wine yeast feel the heat, they begin activating genes for dealing with the stresses of the next stage. ... had evolved to stop activating their maltose genes at the taste of lactose, only turning them on ...

DNA2.0 Awarded US Patents for Breakthrough Gene Optimization Technology -- Company's Unique Algorithm Enables Expression Yields up to 50 Times Greater than Competing Approaches

... 12/184,240--claim methods for designing synthetic genes to reliably increase levels of recombinant ... come to us for synthetic genes, they want those genes to express. The broad and fundamental claims in ... patents, speak to our leadership in designing genes for protein expression." Expression of ...

ASCP Joins ACLU Lawsuit Opposing Gene Patents

... challenging the legality of patents on human genes -- specifically, patents covering the BRCA1 and ... challenging the legality of patents on human genes -- specifically, patents covering the BRCA1 and ... at or interpreting a person's BRCA1 and BRCA2 genes to determine if the person is at a higher risk of ...

Biotechnology Company Provided Advance Warning of Mexican H1N1 "Swine Flu" Virus Outbreak

... which examines specific regions in virus genes which have been linked with past epidemics. The ... which examines specific regions in virus genes which have been linked with past epidemics. ... which examines specific regions in virus genes which have been linked with past epidemics. A ...

Chromosome breakpoints contribute to genetic variation

... source of genetic variation. The functions of genes found in these "breakpoint regions" differ ... the new chromosomes have the same arrangement of genes as the parent cells, but with new combinations of ... been unable to determine how the organization of genes along chromosomes and variation within the ...

International science consortium publishes analysis of domestic cattle genome sequence

... cattle (Bos taurus) contains approximately 22,000 genes and shares about 80 percent of its genes with humans. The researchers also report that the ... some of these chromosomal rearrangements affect genes related to immunity, metabolism, digestion, ...

Genomic Health Announces Positive Preliminary Results from QUASAR Validation Study of Oncotype DX(R) Colon Cancer Assay

... 1,800 colon cancer patients and 760 candidate genes were evaluated in four clinical studies to select the genes for the Onco type DX colon cancer assay. The resulting genes were then studied in more than 1,200 stage II ...

Polycystic Kidney Disease Assay at Cornell University Uses Transgenomic's Surveyor Nuclease & WAVE Technology

... scanning of PKD1 and PKD2 , two important genes used in the diagnosis and prognosis of autosomal ... improvement to the workflow for analyzing large genes such as PKD1 and PKD2 , which Hanna Rennert's ... very complex and expensive due to the size of the genes and the variety of mutations involved. ...

Groundbreaking Research Begins for Pancreatic and Lung Cancers

... technology allows examination of more than 20,000 genes in a single experiment. Differences in the expression of genes encoding cellular proteins are of special ... the research team hopes to identify the genes which mediate resistant. Identification of the ...

Genomic Study Shows Organic Skin Care Product Activates Key Anti-Aging Gene

... Chain Reaction (PCR) and is able to imeasure genes turned "on" or "off" by skin ... of specific collagens, keratins and matrix genes that promote anti-wrinkle effects in a ... activates anti-oxidant and anti-inflammatory genes involved in protective cellular mechanisms in a ...

Venter Institute Launches the J. Robert Beyster and Life Technologies 2009-2010 Research Voyage of the Sorcerer II Expedition

... so far discovered approximately 20 million new genes and thousands of new protein families, we are ... will add to the growing catalogue of microbes and genes my team has been compiling through the Sorcerer ... Bermuda's Sargasso Sea in which 1.2 million new genes and more than 1,800 new species were identified, ...

Proteomics Study Reveals That Genes Involved in Invertebrate Longevity Have Surprising Parallels in Humans.

... today the publication of the discovery of genes that are likely to have a role in the aging ... Though the existence of longevity-extending genes has been known for experimental organisms such as ... this is the first demonstration that similar genes have a role in the aging process of humans. ...

DNA2.0 Introduces Freedom of Expression With a New Family of Bacterial Expression Vect:ors

... of the world with lax IP protection, all DNA2.0 genes are made at the company's state-of-the-art ... and biotechnology industries. DNA2.0 has provided genes to thousands of customers, for whom it has ... DNA2.0 explores novel applications for synthetic genes and is exploiting the synergy between highly ...

Discovery of a new retinal gene involved in childhood blindness

... genetic therapy. Gene therapy targeting different genes has recently proved successful for the same ... have now identified a total of fifteen genes involved in LCA, but SPATA7 is the first gene ... gene therapies. Therapies targeting different genes for the same disease have already shown success ...

Mathematical models reveal how organisms transcend the sum of their genes

... models of a relatively simple virus to show that genes alone do not make an organism. With mathematical ... new paper, simply shuffling the order of the five genes in the virus's genome has a huge impact on how ... Yin says. "How does the biology of individual genes come together in genetic interactions to ...

Mosquito genes linked to insecticide resistance may be new target in fight against malaria

... ), researchers have identified specific mosquito genes associated with resistance to a common class of ... genetic culprits to members of a family of genes coding for enzymes known as cytochrome P450s. ... The researchers found two cytochrome P450 genes in An. funestus that are associated with ...

AngioGenex Presents Data on its Id Targeted Anti-Angiogenesis Inhibitors at Two Scientific Conferences

... company that is pioneering the targeting of Id genes and proteins for the discovery and development of ... new blood vessel formation into tumors by the Id genes and proteins confirms that drugs that inhibit ... molecules that act by inhibiting either the Id genes or proteins to prevent the formation of new blood ...

New Collaboration Aims To Expand Seed-Based Technologies, Benefit Farmers

... Another goal of the collaboration is to identify genes that help plants fight environmental stresses ... will provide a means of rapidly moving new genes and promoters into the field." About ... The RootArray facilitates the discovery of genes and gene promoters that could produce ...

Cardiovascular Side Effects of Pioglitazone and Rosiglitazone Linked to Vascular and Energy Pathways by Genomas Clinical Study

... statistically significant associations of certain genes in vascular and energy pathways to body mass ... A total of 222 cardiometabolic and neuroendocrine genes were selected and a physiogenomic analysis was ... BMI, the strongest associations were found among genes involved in energy homeostasis, adiposity, ...

DuPont and Athenix Collaborate to Advance Insect Control in Corn, Soybeans

... will use proprietary insect-resistance trait genes from Athenix to develop and commercialize ... have exclusive ownership of novel insect control genes enhanced through its gene shuffling technology ... crop production industry; and 2) the discovery of genes and proteins for use in the sustainable chemical ...

Genomic Health Announces Commencement of QUASAR Clinical Validation Study for Oncotype DX(R) Colon Cancer Assay

... more than 1,800 patients and 760 candidate genes to select the final 18-gene set for the Oncotype ... development studies to identify and select the 18 genes for the Oncotype DX colon cancer assay. The ... Recurrence Score, the prognostic and predictive genes in the colon cancer assay do not overlap. As ...

WaferGen's SmartChip(TM) System Performance Successfully Demonstrated in Initial Phase of Alpha Testing Program

... the product's complete workflow on 1,000 oncology genes using small amounts of samples from emphysema, ... control genes, as well as indicators of other genes that are known to be expressed in ... the ability to capture the expression of genes that have not been able to be seen using ...

AngioGenex Reviews 2008 Achievements and Sets Goals for 2009

... biotechnology company that leads in targeting Id genes and proteins for the discovery and development of ... molecules that act by inhibiting either the Id genes or proteins to prevent the formation of new blood ... City who established that activation of the Id genes is required for the formation of new blood ...

RNAi Helps Illuminate the Inner Workings of the Cell Cycle: Synthetic RNAissance™ Genes Created by DNA2.0 Enable Key Research

... DNA2.0 has designed RNAi-resistant genes that enabled a breakthrough in understanding the ... workings of the cell cycle. DNA2.0's RNAissance genes are simultaneously optimized for expression in ... announced today that the company's RNAissance genes had been used to shed new light on the mechanisms ...

Unraveling the genetic picture of lung cancer

... 23, 2008) -- A study seeking possible cancer genes elucidated the mutations and the genetic pathways ... called the Tumor Sequencing Project identified 26 genes that play a significant role in the development ... members of the consortium sequenced key candidate genes from 188 tumor samples and matching non-cancerous ...

Large-scale genetic study sheds new light on lung cancer

... Sequencing Project (TSP) consortium identified 26 genes that are frequently mutated in lung ... achievement that more than doubles the number of genes known to be associated with the deadly disease. ... forms of lung adenocarcinoma and tumor suppressor genes that would ordinarily prevent cancer cell ...

deCODE Discovery Sheds Light on Risk of the Most Common Form of Skin Cancer

... variants in or near the MC1R, ASIP, TYR and TYRP1 genes that deCODE has reported in earlier studies. ... and resources have enabled us to isolate key genes contributing to major public health challenges from cardiovascular disease to cancer, genes that are providing us with drug targets rooted in ...

Repligen Announces Publication of Positive Results with Proprietary HDAC Inhibitor in Huntington's Disease Model

... were also analyzed for changes in the hundreds of genes whose expression in the brain is altered in the ... gene microarrays, the researchers identified genes in three brain regions whose expression was ... treating Huntington's disease and that specific genes may be useful as biomarkers in clinical trials. ...

RainDance and Scripps to Collaborate on Targeted Sequencing for 'Wellderly' Study

... a diverse set of samples. "Looking at the genes of healthy elderly people is a unique approach ... and clinical programs focused on defining the genes that underlie susceptibility to disease, and will ... ancestry in an attempt to identify and define genes responsible for major disease and the ...

DOE JGI Director Eddy Rubin highlights the genomics of plant-based biofuels in the journal Nature

... to degrade cellulose, and fungi that express genes associated with the decomposition of the most ... a better picture of the metabolic potential of genes and how they can be enlisted for the enzymatic ... November 2007]), which has yielded more than 500 genes related to the enzymatic deconstruction of ...

Xceed Molecular to Launch New Inflammation Xpress Chip(TM)for the Ziplex(R) Automated Gene-Expression Analysis System at Clinical Lab Expo 2008, Booth 2155

... in general. Expression changes in specific genes and pathways represented on the Inflammation ... Inflammation Xpress Chip) contain published genes of interest for common pathways or disease ... arrays. Xceed's Metabolic Xpress Chip offers genes of interest for investigators exploring metabolic ...

Symbiotic microbes induce profound genetic changes in their hosts

... including a set of evolutionarily conserved genes that may hold the secrets to developing a ... colonize their host. They identified hundreds of genes affected by the establishment of a stable ... to bacteria. The involvement of several genes typically associated with responses to bacterial ...

New technique produces genetically identical stem cells

... cells using lentiviruses to randomly insert four genes (Oct4, Sox2, c-Myc and Klf4) into the cells' DNA. ... cells also were modified to switch on these four genes when a drug trigger, doxycycline, is added to the ... the viruses used to insert the reprogramming genes could integrate anywhere in the cell's DNA with ...

Dow AgroSciences Announces Early Exercise of Option for Commercial License With Sangamo BioSciences for Plants

... precision to add new genetic material, delete genes altogether and even regulate or edit native ... The ability to selectively control specific genes is emerging as a critical tool in modern ... and precise targeting to a particular gene or genes of interest. Sangamo BioSciences and Dow ...

New molecular imaging techniques may lead to advances in disease treatment

... research shows that using antibodies as reporter genes in PET imaging provides these capabilities and ... These data indicate that antibody-based reporter genes represent a promising new platform for the ... probe combinations. Antibody-based reporter genes have several potential advantages over other ...

Dow AgroSciences, Sangamo BioSciences Announce the Achievement of Key Milestones in Plant Agriculture Collaboration

... of the ZFP platform to both regulate and modify genes in commercially important plant species. We have ... control of the expression of existing genes. Many genes have already been identified in crop species that ... The ability to selectively control specific genes is emerging as a critical tool in modern ...