Cells in Biological Technology

ThermoGenesis Announces Expanded Collaboration With Celling Technologies

... for the concentration of bone marrow-derived stem cells at the point of care. Celling will be the ... disposable bag set for concentrating stem cells derived from bone marrow. It allows clinicians ... blood processing disposables for harvesting stem cells in closed systems. The AXP device is used for the ...

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

... therapeutic potential of targeting cancer stem cells to treat solid tumors. OMP-21M18 is currently in ... Cell suggests that reducing the ratio of these cells within tumors may dramatically improve ... decreased the proportion of cancer stem cells found in tumors compared to chemotherapy alone. ...

Plastics that convert light to electricity could have a big impact

... world over are striving to develop organic solar cells that can be produced easily and inexpensively as ... light to electricity. The goal is to develop cells made from low-cost plastics that will transform ... that threshold, nanostructured plastic solar cells could be put into use on a broad scale, he said. ...

W.M. Keck Foundation Awards $1 Million to Hutchinson Center Scholar to Study How Cells Go Awry

... cancer knows the rapidly growing, opportunistic cells don't play fair. But in order to expose exactly how cancer cells cheat their host, scientists must first study the ... enhances the potential for learning how cancer cells cheat - Fred Hutchinson Cancer Research Center ...

Micromet Receives European Orphan Drug Designation for Treatment of Acute Lymphoblastic Leukemia with BiTE Antibody Blinatumomab

... therapeutic antibody that activates a patient's T cells to seek out and destroy cancer cells. In ... but retained a detectable level of ALL cancer cells in their bone marrow - so called minimal residual ... a new class of antibodies that activate the T cells of a patient's immune system to eliminate cancer ...

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

... Company's studies have shown that proliferative cells migrate into the Gene Activated Matrix and then ... the availability of therapeutic proteins to the cells performing tissue repair and lower the overall ... a key role in the transformation of mesenchymal cells into bone and naturally recruit ...

United States FDA Clears the REGEN Trial to Test Bioheart's Combination Gene and Stem Cell Therapy in Heart Failure Patients

... MyoCell SDF-1 is a composition of myogenic stem cells derived from a patient's own thigh muscle that ... patient who is suffering from heart failure, the cells are injected into the scar tissue that has formed ... Bioheart has acquired covering the myogenic cells and SDF-1 compositions and methods are expected ...

Junying Yu, Leading Stem Cell Researcher, Joins Cellular Dynamics International

... the power of induced pluripotent stem (iPS) cells to reproducibly differentiate into essential cell ... in developing commercially available terminal cells (e.g. heart, blood, neural cells, etc.) derived from iPS cells for drug development. This progress has been ...

Heart disease: Research off the beating patch

... us to introduce living, healthy heart muscle cells into damaged areas of the heart in a way that is ... the conventionally practiced method of injecting cells into heart tissue," says study leader Steven ... Unlike most existing approaches, in which cardiac cells with no supporting structure are injected into ...

NeoStem, Inc. Appoints Leading Chinese Medical Official to Its Advisory Board

... processing and long-term storage of adult stem cells for future medical need, announced today it has ... to donate and store their own (autologous) stem cells when they are young and healthy for their ... that are generally found in embryonic stem cells and is pursuing other technologies to advance its ...

NeoStem Featured on CBS2 News; Success of Licensed Stem Cell Treatments Shown for Arthritis and Orthopedic Problems; Procedure to be Used by NeoStem Affiliate in China

... processing and long-term storage of adult stem cells for future medical need, was featured on CBS2 ... that rapidly grows a patient's own adult stem cells to treat a variety of musculoskeletal diseases. ... medical expert, stated that autologous adult stem cells "have become the cutting edge way to treat ...

Cellular Dynamics International In-Licenses Key Patent Portfolio for Using Stem Cell-Derived Cells in Drug Testing

... selection process and on using heart cells (cardiomyocytes) in drug testing. The ... important concepts for using stem cell-derived cells for drug screening. First, the Field patents ... requirement for commercial application of these cells as tools in the pharmacology and toxicity testing ...

Significant Milestone Marks the Beginning of FDA-Authorized Breast Cancer Trial

... as a cancer antigen (a protein found on cancer cells that can be targeted by the body's own immune ... own immune system to target and attack the cancer cells with the intent to improve patient survivability ... monthly injections of the patient's own dendritic cells that have been sensitized to OFA. It is ...

New method may accelerate drug discovery for difficult diseases like Parkinson's

... of Nature Chemical Biology , uses baker's yeast cells to perform most of the same work in a matter of ... He then inserted the cyclic peptides into cells of a well-established yeast model of Parkinson's ... rigidity, and slowed movements. In the neural cells of Parkinson's patients' brains, researchers have ...

Novel drug discovery tool could identify promising new therapies for Parkinson's disease

... the researchers showed that they can rescue yeast cells from toxic levels of a protein implicated in Parkinson's disease by stimulating the cells to make very small proteins called cyclic ... peptides had a protective effect on the yeast cells and on neurons in an animal model of Parkinson's ...

Nanopillars promise cheap, efficient, flexible solar cells

... demonstrated a way to fabricate efficient solar cells from low-cost and flexible materials. The new ... early attempts to make photovoltaic cells based on pillar-shaped semiconductors grown from ... to 18 percent range of mass-produced commercial cells is higher than most photovoltaic devices based on ...

Stem cells' 'suspended' state preserved by key step, scientists report

... a gene that is essential for embryonic stem cells to maintain their all-purpose, pluripotent state. ... may lead to a greater understanding of how cells acquire their specialized states and provide a strategy to efficiently reprogram mature cells back into the pluripotent state, an elusive step ...

Cellular Dynamics International Reprograms Blood Cells into Stem Cells

... a readily obtainable source of pluripotent stem cells from the millions of samples in storage at blood ... "Industry's challenge was to reliably create iPS cells from a commonly available and easily accessible ... officer of CDI. "Generating pluripotent stem cells from small volumes of blood, either freshly ...

iZumi Bio and Pierian Merge to Form iPierian to Advance Cellular Reprogramming

... therapeutics using induced pluripotent stem (iPS) cells for patients with difficult-to-treat diseases. ... "Disease-specific pluripotent stem cells are powerful new tools for drug screening and ... whose lab first succeeded in inducing iPS cells in mouse. Newly Formed Scientific Advisory ...

Cellular Dynamics International and Roche Expand Existing Cardiotoxicity Screening Agreement

... created from induced pluripotent stem cells (iPSCs), to Roche, and the two companies will ... as toxicology tool. iPSCs are adult tissue cells that have been reprogrammed to a pluripotent, ... CDI harnesses the power of pluripotent stem cells and their ability to differentiate into any cell ...

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... presented data that showed that blood and spleen cells from immunized mice produced gamma interferon in response to the vaccine, while the cells from mice in the various control groups did not. ... can activate and cause human blood monocyte cells to become ...

UCF team's advanced nerve cell system could help cure diabetic neuropathy, related diseases

... and spinal cord, where the damage from MS occurs, cells called oligodendrocytes surround the nerves and ... with diabetic neuropathy originate, Schwann cells perform this function. Due to the famous ... recognized the need for lab-grown motor nerve cells that myelinate and form nodes of Ranvier so that, ...

NeoStem Featured in Business Week; 'Promising' Adult Stem Cell Market Discussed in Fortune-CNNMoney.com Article

... processing and long-term storage of adult stem cells for future medical need, was featured in Gene ... (NBS), which collects and stores adult stem cells for future medical use, have helped catapult its ... article, which compares prospects for adult stem cells versus those for embryonic stem cells, also notes ...

Cord Blood America Continues International Expansion

... on bringing the life saving potential of stem cells to families nationwide and internationally, which ... compelling advantages. We see the storage of stem cells internationally as potentially very profitable. ... be lucrative. The advantages of storing stem cells at birth, and at other times in life, are ...

Fallopian tubes offer new stem cell source

... could be a rich additional source of stem cells for regenerative medicine. New research from ... fallopian tubes are abundant in mesenchymal stem cells which have the potential of becoming a variety of ... has previously been shown that mesenchymal stem cells obtained from umbilical cords, dental pulp and ...

Scientists identify gene vital to early embryonic cells forming a normal heart and skull

... regions of the embryo. While doing so, the cells are supposed to differentiate and give rise to ... show that a deficiency of SHP2 in neural crest cells results in a failure of cell differentiation at ... trigger a cascade of biochemical reactions in cells as they specify to form certain tissues. ...

A Worldwide Milestone in Cell Analysis - 40 Years of Flow Cytometry

... procedures. Using most modern optoelectronics, cells and particles of small size, even in nanometer range, are detected. The cells are marked with specific reagents and excited by ... signals are collected. With the obtained data, cells can be characterized, classified, quantified and ...

Data Presented at Society of Nuclear Medicine 2009 Annual Meeting Supports Potential of Peregrine's Cotara(R) for the Treatment of Brain Cancer

... GBM patients. Cotara specifically targets cells at the center of brain tumors, so its radioactive payload is able to kill cancer cells while leaving healthy tissue largely unaffected. ... histone complex that is exposed by dead and dying cells found at the center of solid tumors. Cotara's ...

NeoStem Signs Agreement with Shanghai Corporation to Develop A Stem Cell Collection and Treatment Network in Shanghai, Taiwan and Other Targeted China Provinces

... processing and long-term storage of adult stem cells for future medical need, announced today it has ... and systems that allow adults to have their stem cells safely collected and conveniently banked through ... to donate and store their own (autologous) stem cells when they are young and healthy for their ...

Assessment of safety and efficacy of human embryonic stem cell therapy

... online ahead of print in the journal Stem cells , shows long-term functional rescue using hESC-derived cells in both the RCS rat and Elov14 mouse, animal ... degeneration and Stargardt, respectively. The cells survived transplantation for prolonged periods ...

iZumi Bio Appoints Dr. Corey Goodman to Board of Directors and Scientific Advisory Board

... iZumi's technology involves reprogramming somatic cells to a pluripotent state. Because iPS cells have stem-cell-like properties and have the potential to differentiate into any cell type, iPS cells are considered to be of great potential for ...

NeoStem, Inc. Appoints Financial Expert with Broad International Experience to the Board of Directors and to Serve as Chairman of the Company's Audit Committee

... processing and long-term storage of adult stem cells for future medical need, announced today it has ... to donate and store their own (autologous) stem cells when they are young and healthy for their ... that are generally found in embryonic stem cells and is pursuing other technologies to advance its ...

Celator(R) Pharmaceuticals Presents Data on the Activity of CPX-351 Against Leukemia at the European Hematology Association Congress

... led the investigators to conclude that leukemia cells could be exposed to cytotoxic drug levels ... the uptake of CPX-351 by human leukemia cells both in vitro and in vivo (mouse xenograft ... They reported that CPX-351 ablated leukemic cells but permitted the regrowth of normal bone ...

Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on GenSpera, Inc.

... cells. GenSpera's prodrugs target cancer cells in one of two ways: (1) by targeting ... technology can also be used to attack cancer cells directly by targeting the prodrug to enzymes ... antigen (PSA), a protein produced by the cells of the prostate gland that is used by physicians ...

Celsense, Inc Receives NIH Grant to Translate Cell Imaging Technology for Clinical Use

... The Cell Sense technology makes transplanted cells visible by MRI. Therapeutic cells are labeled ex vivo with the Cell Sense reagent ... data from pre-clinical studies using human cells show that the Cell Sense reagent is highly ...

Ascenta Therapeutics Announces Presentation of Promising Results From Clinical Trials of AT-101 in Prostate, Brain, and Lung Cancers at 2009 ASCO Annual Meeting

... per RECIST. A reduction in circulating tumor cells was also reported after the first cycle of ... factors, AT-101 lowers the threshold for cancer cells to undergo apoptosis in various tumor types. ... that restore the natural potential for cancer cells to undergo cell death (apoptosis). Ascenta's ...

NIMOTUZUMAB DEMONSTRATES EFFICACY IN RANDOMIZED HEAD & NECK CANCER STUDY WITHOUT THE TOXICITIES ASSOCIATED WITH OTHER EGFR DRUGS

... of that drug to discriminate between healthy cells and tumor cells," said David Allan, Chairman and ... target the higher density of EGFR found in tumor cells while avoiding the lower density of EGFR in the cells of skin, kidney and gut. In the clinical setting, ...

OncoGenex Pharmaceuticals Announces OGX-427 Treatment Demonstrates Safety, Evidence of Declines in Circulating Tumor Cells and Reductions in Tumor Markers in a Phase 1 Cancer Trial

... demonstrated declines in circulating tumor cells at all doses evaluated as well as evidence of ... in tumor markers. Reductions in circulating tumor cells and tumor markers both suggest single-agent ... and Tumor Marker Results Circulating tumor cells (CTCs), an emerging metric to assess treatment ...

New Cellular Bioenergetics Workshops Series Inaugurated by Seahorse Bioscience with Two of the World's Leading Bioenergetics Researchers

... " Understanding When and How to Use Intact cells and Isolated Mitochondria in Investigating ... on putting bioenergetics in the context of living cells is necessary in order to gain a better ... how the function of mitochondria within living cells is regulated to give the exquisite control of ...

MIT, BU engineer cellular circuits that count events

... and Boston University engineers have designed cells that can count and "remember" cellular events, ... Performing very elaborate computing inside cells would be extremely difficult because living cells are much harder to control than silicon chips. ...