causative in Biological Technology

MEDomics Announces MitoDx(TM), the First NextGen Mitochondrial Genome Diagnostic Test

... dystrophy or cancer. Most mitochondrial disease may go undiagnosed because a primary care physician does not suspect the disease or because the causative mutation is missed by current methods. " To my knowledge, MEDomics is the first laboratory to offer a whole genome clinical diagnostic test ...

Thomson Reuters Examines Highly Cited Research in Bioterrorism

... third spot was the Imperial College of London with an impact of 31.55. The most cited bioterrorism paper was published in 2001, regarding the causative agent of plague, Yersinia pestis; this paper has been cited nearly 500 times. The second most cited paper, entitled "Anthrax," was published two ...

Sequella Commences Phase 1B Study for New Tuberculosis Drug SQ109

... activity against drug sensitive and both multi-drug resistant and extensively-drug resistant (MDR and XDR) Mycoba c terium tubercul o sis , the causative agent of tuberculosis (TB). The Phase 1B study will assess safety, pharmacokinetics and tolerability of multiple ascending doses of SQ109 in three ...

Science Magazine to Host Webinar on Advances in Cancer Genomics

... for cellular growth and/or cell death. Despite advances, technological limitations or excessive cost have historically restricted research into causative factors. Next-generation genomic platforms now are enabling scientists to study individual genomes in more depth, giving them a better understanding ...

Researchers at the University of Georgia Discover Protein is Crucial to Reproduction of Parasites Involved in Disease

... of the parasite. "Understanding that DrpA is necessary for apicoplast fission gives researchers a new working model to understand how the causative agents of several parasitic diseases flourish in human and animal hosts," said van Dooren. Indeed, the team's search for similar ...

Tips from the journals of the American Society for Microbiology

... report their findings in the August 2008 issue of the journal Infection and Immunity . Transmitted by infected fleas, Yersinia pestis is the causative agent responsible for bubonic and pneumonic plague. Both highly contagious, the bubonic form of the disease is the most common in the world and can ...

Tips from the journals of the American Society for Microbiology

... report their findings in the August 2008 issue of the journal Infection and Immunity . Transmitted by infected fleas, Yersinia pestis is the causative agent responsible for bubonic and pneumonic plague. Both highly contagious, the bubonic form of the disease is the most common in the world and can ...

FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania

... during the first few months of therapy. In these patients, SEROQUEL XR should be discontinued at the first sign of a decline in WBC absent other causative factors. Patients with neutropenia should be carefully monitored, and SEROQUEL XR should be discontinued in any patient if the absolute neutrophil ...

Tips from the journals of the American Society for Microbiology

... report their findings in the August 2008 issue of the journal Infection and Immunity . Transmitted by infected fleas, Yersinia pestis is the causative agent responsible for bubonic and pneumonic plague. Both highly contagious, the bubonic form of the disease is the most common in the world and can ...

Industry Pioneer Joins Profectus BioSciences to Support Innovation in Therapeutic and Preventative Vaccines

... technologies to reduce the morbidity and mortality caused by human viral diseases, including the human immunodeficiency virus (HIV), the causative agent of AIDS. Founded to fulfill the mission of its co-founders Drs. Gallo, Blattner, and Redfield (collectively, the founders) for ...

Arpida's iclaprim MAA Accepted for Review by EMEA

... patients were treated). Patients enrolled in the Phase III trials exhibited a high incidence of methicillin-resistant Staphylococcus aureus (MRSA) as causative pathogen. In both of these two independent Phase III trials, intravenous iclaprim achieved the pre-specified primary endpoint of non-inferiority as ...

Sagent Pharmaceuticals Launches Ceftriaxone, USP, and Cefuroxime for Injection, USP

... gonorrhea. In certain cases of confirmed or suspected gram-positive or gram-negative sepsis or in patients with other serious infections in which the causative organism has not been identified, cefuroxime may be used concomitantly with an aminoglycoside. Cefuroxime may be used prophylactically to prevent ...

Isabel Healthcare Adds Hospitals in Wisconsin & Minnesota

... base contains all age groups, has 11,000 diagnoses including bio-terrorism and other emergency preparedness situations. It also contains 4,200 causative drugs. Isabel is available as a web-based stand-alone subscription or can be purchased interfaced with several EMR partner systems. Based in Falls ...

/C O R R E C T I O N -- Mobidiag Ltd/

... The challenge in sepsis treatment is starting adequate treatment with the appropriate antibiotics on time. Currently, the diagnostics of causative pathogen(s) needed for the antibiotic treatment decision takes 2-5 days based on blood culturing and subsequent pathogen identification. Using ...

Scientists develop strategy to rapidly describe outbreak strains with next-generation DNA sequencing

... of this work was to evaluate the recently available automated pyrosequencing technology without finishing for this purpose. F. tularensis , the causative pathogen of tularemia, is one of the most infectious bacteria known, and there is particular concern that this organism could be manipulated for use ...

AstraZeneca Submits sNDA for SEROQUEL XR(TM) for the Treatment of Major Depressive Disorder

... first few months of therapy. In these patients, SEROQUEL and SEROQUEL XR should be discontinued at the first sign of a decline in WBC absent other causative factors. Patients with neutropenia should be carefully monitored, and SEROQUEL and SEROQUEL XR should be discontinued in any patient if the ...

Profectus BioSciences Inc. Names Shawn Patrick O'Brien CEO

... technologies to reduce the morbidity and mortality caused by human viral diseases, including the human immunodeficiency virus (HIV), the causative agent of AIDS. Founded to fulfill the mission of its co-founders Drs. Gallo, Blattner, and Redfield (collectively, the founders) for "bench- ...

GeneSeek Selects the British Midlands as Base for New UK/European Operations

... industries. We provide customers with a full range of solutions, from basic research to high throughput genomic screening for predictive and causative mutations, clinical diagnostics systems and devices, and therapeutic protein production and discovery. GeneSeek enables development, testing and ...

OpGen Database Helps to Reduce Bioterrorist Threat

... DNA. One of the most infectious bacteria, Francisella tularensis, is a causative agent of Tularemia, a disease often referred to as rabbit or deer fever. ... genome map of this Category "A" pathogen. Early identification of the causative agents in disease outbreaks, whether natural, or the result of bioterror ...

Use of the DCode System to Detect the Food-Borne Bacterial Pathogen Listeria monocytogenes

... involve culture and incubation for positive identification of causative agents of disease delays implementation of preventive action to ... techniques that provide positive identification of the causative agent of disease without the need to culture the suspect ...

Americas Third Coast nurtures biotechnology

... at OpGen are constructing a database of infectious agents as a resource for rapid identification of suspect organisms. Early identification of the causative agents in disease outbreaks is critical to mounting an effective response, says Dr. Dykes. Bone Care International ( www.bonecare.com ) ...

SNPs Powerful Tools for Association Studies

... change that results in a RFLP is also the causative change (i.e., an A-to-T change in the number two ... focus the search for possible surrogate or causative SNPs in candidate gene or candidate region ... forms of a gene or a genetic locus. causative SNPs Changes in a single nucleotide that cause ...

Separation and Comparison of Proteins From Virulent and Nonvirulent Strains of the Fish Pathogen Flavobacterium psychrophilum, Using a 2-D Electrophoretic Approach

... In Faisal M and Hetrick FM (ed), Annu Rev Fish Dis, New York, Pergamon Press, 127144 (1993) Holt RA, Cytophaga psychrophila, the causative agent of bacterial coldwater disease in salmonid fish, PhD thesis, Oregon State University, Corvallis, Oregon (1987) ...

Preparative SDS-PAGE Electrophoresis of a Recombinant Epstein-Barr Virus Encoded Protein and Its Application in Serodiagnostic Test Systems, Rev C

... recombinant proteins to near homogeneity. Epstein-Barr virus (EBV) is an ubiquitous human B-lymphotropic herpesvirus. It is the causative agent of infectious mononucleosis, a mostly self-limiting lymphoproliferative disease, and is closely associated with an increasing ...