Arthritis in Biological Technology

Video: New Way RA(TM) Talk Show Premieres Online for People Living With Rheumatoid Arthritis (RA)

... and information for adults living with rheumatoid arthritis (RA). Deborah Norville and expert guests discuss ... of New Way RA .) About Rheumatoid arthritis Rheumatoid arthritis is characterized by persistent and progressive ...

Schering-Plough Reports Financial Results for 2009 Second Quarter

... therapy for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis; SIMPONI was also ... the signs and symptoms in patients with psoriatic arthritis and ankylosing spondylitis. Separately, a new ... with moderately to severely active rheumatoid arthritis who received subcutaneous injections of SIMPONI ...

New Survey Reveals That More Than Half of Rheumatoid Arthritis Patients in Europe and Canada Feel Their Disease Controls Their Lives

... Surveyed Experience Daily Pain From Rheumatoid arthritis Despite Current Treatment; Findings Unveiled at ... (RAISE) survey of more than 500 rheumatoid arthritis (RA) patients throughout Europe and Canada ... public polling organization. "Rheumatoid arthritis is a debilitating disease that has a significant ...

Resverlogix's Success in Inflammation Program Results in 2 Patents Filed

... results achieved in the collagen induced arthritis (CIA) model in rats demonstrated that ... example, a small molecular drug for rheumatoid arthritis is estimated to range in price from US $180 - US ... annum. In 2007, the global market for rheumatoid arthritis alone was estimated to be in excess of US $11 ...

Rigel Announces First Quarter 2009 Financial Results

... Phase 2b clinical trials of R788 in rheumatoid arthritis (TASKi2 and TASKi3) . As a result of the ... patients studied with R788 in rheumatoid arthritis to the 189 patients studied from our Phase 2a ... diseases such as rheumatoid arthritis thrombocytopenia and asthma, as well as in ....

Health Canada Approves SIMPONI(TM) (golimumab) for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... of moderately to severely active rheumatoid arthritis (RA), active psoriatic arthritis (PsA) and active ankylosing spondylitis (AS). ... of RA, PsA and AS. About Rheumatoid arthritis RA is a chronic and debilitating disease ...

Trubion Pharmaceuticals Inc. Announces Work-Force Reductions and Restructuring

... -- Announce TRU-015 Phase 2b (15002) rheumatoid arthritis re-treatment data at the annual meetings of the ... -- Announce TRU-015 Phase 2b (2203) rheumatoid arthritis trial data by end of Q4 2009 (currently ... -- Announce SBI-087 Phase 1 rheumatoid arthritis trial data by end of Q4 2009 (currently ...

Antiangiogenic Role of 2ME2 Demonstrated in Rheumatoid Arthritis Models

... (Panzem(R) or 2- methoxyestradiol) in rheumatoid arthritis (RA). The results of the study, conducted by ... involutes rat collagen-induced arthritis and suppresses synovial VEGF and bFGF ... in a preclinical model of established rheumatoid arthritis demonstrated that daily oral administration of ...

Rigel Announces Third Quarter 2008 Financial Results and Clinical Update

... Phase 2b clinical trials of R788 in rheumatoid arthritis (TASKi2 and TASKi3). Stock-based compensation ... R788 Rigel expects that R788 for rheumatoid arthritis will continue to be the primary clinical focus ... Rigel does not plan to start a second rheumatoid arthritis program at this time so as not to compete with ...

Golimumab Phase 3 Data Show Significant Improvement In Physical Function In Patients with Rheumatoid Arthritis

... with active moderate to severe rheumatoid arthritis (RA) were presented at the American College of ... alone (P < 0.001). According to the arthritis Foundation, in addition to joint pain ... five pivotal Phase 3 trials in RA, psoriatic arthritis and ankylosing spondylitis. About the GO-AFTER ...

From Pain to Unexpected Fame: One Woman's Journey to Know Fibro

... Lawrence, et al. "Estimates of the Prevalence of arthritis and Other Rheumatic Conditions in the United States." arthritis and Rheumatism 2008; 58(1):31. (2) Leventhal, ... of fibromyalgia in the general population." arthritis Rheum 1995; 38(1):19-28. (4) Wolfe, F, et al. ...

One-Year Data Show Golimumab Improved Signs and Symptoms In Patients with Psoriatic Arthritis In Phase 3 Study

... substantial improvements in physical function and arthritis and psoriasis components of the disease. ... of Safety and Efficacy in Subjects with Psoriatic arthritis Using a Human Anti-TNF Monoclonal Antibody ... achieved at least 20 percent improvement in arthritis signs and symptoms as measured by ...

MedImmune Presents Data Highlighting its Progressive Inflammatory Disease Portfolio at the 72nd Annual Meeting of the American College of Rheumatology

... called follicles. In patients with rheumatoid arthritis the levels of CXCL13 are elevated within the ... reduces severity of established experimental arthritis - Matthew Sleeman, Ph.D., Monday, October 27 ... for the treatment of patients with rheumatoid arthritis - Matthew Sleeman, Ph.D., Tuesday, October ...

ACTEMRA(R) (tocilizumab) Studies to be Featured at American College of Rheumatology Annual Scientific Meeting

... Outcomes in Patients with Rheumatoid arthritis Who Have Inadequate Response to TNF ... rheumatoid arthritis, juvenile idiopathic arthritis and systemic-onset juvenile idiopathic arthritis were also approved in Japan. The serious ...

Ardea Biosciences' Advances RDEA806 Into Phase 2a Proof-of-Concept Study for Gout

... Gout and with the Outcome Measures for Rheumatic arthritis Clinical Trials (OMERACT) group for chronic gout. He serves on the editorial boards of arthritis Rheumatism (Care & Research), Bone Joint Spine, ... but he has also investigated lupus, rheumatoid arthritis and fibromyalgia. Dr. Perez-Ruiz has published ...

Ardea Biosciences Presents Inflammation Program Data for Arthritis and Gout at 2008 Annual European Congress of Rheumatology

... in Animal Models of arthritis - - RDEA594 Shows Promise as an Effective ... in ankle swelling in the adjuvant-induced arthritis model in rats; -- Reduced arthritic scores by up to 82% in the collagen antibody-induced arthritis model in mice. "We are making excellent ...

Phase 3 studies show golimumab significantly improved signs and symptoms of rheumatoid arthritis

... in the signs and symptoms of rheumatoid arthritis (RA) as well as in physical function and disease ... studies for the treatment of RA, psoriatic arthritis and ankylosing spondylitis. In the study, ... director of the Rebecca MacDonald Centre for arthritis & Autoimmune Disease at Mount Sinai Hospital in ...

Professors Marc Feldmann and Sir Ravinder Maini Named Winners of the 2008 Dr. Paul Janssen Award for Biomedical Research

... as an effective therapeutic target for rheumatoid arthritis and other chronic inflammatory conditions ... that have transformed the treatment of rheumatoid arthritis and other chronic inflammatory conditions. ... target for treatment not only in rheumatoid arthritis but also other chronic inflammatory conditions, ...

Centocor, Inc. and Schering-Plough Submit Application Requesting Approval of Golimumab in Europe for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... for adults with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. The ... option for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis," said Jerome A. ... 1,400 adults with moderate to severe rheumatoid arthritis will be presented at the European League Against ...

Wyeth Reports Earnings Results for the 2007 Fourth Quarter and Full Year

... ankylosing spondylitis, psoriatic arthritis and psoriasis. Enbrel is now the leading biotech ... being treated for active early rheumatoid arthritis with Enbrel plus methotrexate compared to ... were from the first major early rheumatoid arthritis clinical trial of a biologic to use clinical ...

Abbott's HUMIRA(R) Receives Positive Opinion From EMEA for Treatment of Moderate to Severe Plaque Psoriasis

... increased background lymphoma risk in rheumatoid arthritis patients with long-standing, highly ... antibody approved for the treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS) and Crohn.s ...

REMICADE(R) Becomes First Anti-TNF Biologic Therapy to Treat One Million Patients Worldwide

... such as rheumatoid arthritis. "Rheumatoid arthritis derailed my life," said Ellen Shmueli, ... and pediatric), ulcerative colitis, rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis and psoriasis. "This significant milestone was ...

More Than 230 Cyclists to Ride in Amgen California Coast Classic Bike Tour to Raise $1.3 Million for Arthritis Foundation

... to raise more than $1.3 million this year for the arthritis Foundation. The Amgen California Coast Classic ... this year," said Dr. Robin Dore, chair of the arthritis Foundation, Southern California Chapter, ... more than $4 million, which continues to help the arthritis Foundation support its research, education and ...

Five Questions About Protopic (tacrolimus) Ointment

... Handout on Health: Atopic Dermatitis. National Institute of arthritis and Muscoskeletal and Skin Diseases. NIH Publication No. 03-4272. Revised ... page 1 Handout on Health: Atopic Dermatitis. National Institute of arthritis and Muscoskeletal and Skin Diseases. NIH Publication No. 03-4272. Revised ...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

... CEL-2000, a L.E.A.P.S. vaccine incorporating a peptide from a rheumatoid arthritis disease protein, was shown to curtail the progression of tissue damage ... since these cytokines cause much of the damage seen in rheumatoid arthritis patients." L.E.A.P.S. technology is a novel T-cell modulation ...

European CHMP Adopts Negative Opinion on Cymbalta for the Treatment of Fibromyalgia

... of Fibromyalgia Patients With or Without Major Depressive Disorder. arthritis Rheum 2004; 50(9):2974-84. (4) Chappell, AS, et al. Duloxetine 60-120 mg ... 1999; 131: 850-858. (7) Arnold, L, et al. Family Study of Fibromyalgia. arthritis & Rheumatism. 2004; 50(3): 944-952. (8) White, et al. Classification, ...

Use of Biologic Agents Continues to Expand Among US Rheumatologists - Can New Agents Shift the Treatment Paradigm in Rheumatoid Arthritis?

... publication, providing insight into the management of Rheumatoid arthritis (RA), Psoriatic arthritis (PsA), and Ankylosing Spondylitis (AS). This report is based on responses ...

Johnson & Johnson Honors 2008 Recipients of The Dr. Paul Janssen Award for Biomedical Research

... factor-alpha (TNF-alpha) as an effective therapeutic target for rheumatoid arthritis and other chronic inflammatory conditions. "Thanks to their pioneering ... that our research defining TNF as a good therapeutic target for rheumatoid arthritis has subsequently led to TNF blockade in Crohn's disease, psoriasis, ...

A Perfect Storm Threatens Patient Access to Specialty Medical Care

... for bone and joint disease. Among the most common joint diseases, arthritis affects approximately 47 million Americans, including 50 percent of ... by 2030, according to the National Center for Health Statistics. Worse, arthritis and other bone and joint diseases are among the most expensive medical ...

Rapid Quantification of Osteoarthritis With a Novel, Office-Based, High-Resolution Digital Imaging Device

... software for the management of rheumatoid arthritis and psoriatic arthritis About D3ATM Medical Systems D3A Medical Systems designs, manufactures ... - KneeAnalyzer(TM) for osteoarthritis, HandAnalyzer(TM) for rheumatoid arthritis and SpineAnalyzer for osteoporosis - are all based on the Optasia(R) ...

Shire Divests Non-Core Product Portfolio to Almirall

... divested included: LODINE(R) (etodolac) for treatment of rheumatoid arthritis and osteoarthritis, COLAZIDE(R) (balsalazide) for treatment of mild to ... CEBUTID(R) (flurbiprofen) for treatment of the symptoms of rheumatoid arthritis and osteoarthritis, ROBAXIN(R) (methocarbamol) for relief of pain from ...

Trubion Pharmaceuticals Announces Upcoming Presentations at American College of Rheumatology Annual Scientific Meeting

... abstracts, including its late-breaking abstract for TRU-015 for rheumatoid arthritis (RA), have been accepted for presentation at the American College of ... Friday, Nov. 9, 2007 Poster L7: TRU-015 Improves Rheumatoid arthritis Disease Activity in a Randomized, Double-Blind, Placebo-Controlled, ...

Nitec's IND Application for Clinical Development With Lodotra Accepted by the FDA

... the efficacy of orally administered low-dose prednisone in Rheumatoid arthritis (RA). Lodotra has the additional, clinically important advantage of ... Lodotra(R), a circadian cytokine modulator for the treatment of rheumatoid arthritis (RA). Nitec was originally founded in 2004 as a spin-out of Merck KGaA. ...

Small Bone Innovations Introduces the Artelon(R) STT Spacer to Increase Treatment Options for Thumb Arthritis

... KY, added: "Artelon is a major advance in the treatment of small joint arthritis by providing an inert interpositioning material between joint surfaces ... of repetitive stress conditions in the thumb leading to earlier onset of arthritis and prompting more surgical procedures such as the use of Artelon spacers. ...

NIH funds support UAB joint replacement research

... The broadened UAB research opportunity is funded by a four-year, $790,931 National Institutes of Health (NIH) grant through the National Institute of arthritis and Musculoskeletal and Skin Diseases (NIAMS). UAB's research, titled Bioengineering Research Partnership (BRP) in Total Joint Replacements, will ...

Centocor Ortho Biotech Inc. Awarded $1.67 Billion Patent Jury Verdict from Abbott Laboratories

... case against Abbott," said Kim Taylor, President, Centocor Ortho Biotech Inc. The patent in question relates to the company's anti-TNF class of arthritis treatments, and is co-owned by New York University and Centocor, for which Centocor is the exclusive licensee. "We are particularly gratified ...

Horizon Therapeutics Names Dr. Jeffrey W. Sherman Executive Vice President and Chief Medical Officer

... pharmaceutical experience to Horizon and will lead the regulatory and clinical strategy for Horizon's investigational therapies for mild-to-moderate arthritis and pain, including HZT-501, a fixed-dose combination tablet containing the most prescribed non-steroidal anti-inflammatory drug (NSAID), ibuprofen, ...

Amgen to Participate in Reproductive Health Drugs Advisory Committee Meeting in August

... have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically ...

Knocking the Wind Out of Asthmatics: Help from Hippocrates

... asthma, perennial rhinitis and skin problems, but also metabolic disorders that interfere with weight loss, and other inflammatory conditions such as arthritis and migraine, without the use of drugs. Hippocrates must be smiling. About Cell Science Systems Cell Science Systems (CSS) is a ...

FDA Appointed Arthritis Advisory Committee Recommends U.S. Food and Drug Administration Approval for KRYSTEXXA(TM) for Refractory Chronic Gout

... Eastern Time EAST BRUNSWICK, N.J., June 16 /PRNewswire-FirstCall/ -- Savient Pharmaceuticals, Inc. (Nasdaq: SVNT ) announced today that the arthritis Advisory Committee appointed by the U.S. Food and Drug Administration (FDA) recommended by a vote of 14 to 1 that KRYSTEXXA(TM) (pegloticase), a ...