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Vessels in Biological Technology

Angiotech Pharmaceuticals announces FDA approval of next-generation TAXUS(R) Liberte(R) Atom(TM) Stent system

... coronary vessels. It was approved for use in vessels as small as 2.25 mm in diameter and joins the ... percutaneous coronary interventions have small vessels ((less than)2.5 mm). Until recently, many ... treatment choice for patients with small vessels who will now have the additional option of the ...

FDA Approves Boston Scientific's Next-Generation TAXUS(R) Liberte(R) Atom(TM) Stent System

... coronary vessels. It was approved for use in vessels as small as 2.25 mm in diameter and joins the ... percutaneous coronary interventions have small vessels (<2.5 mm). Until recently, many physicians ... treatment choice for patients with small vessels who will now have the additional option of the ...

Old and new therapies combine to tackle atherosclerosis

... plus a statin could stop the growth of tiny blood vessels that feed arterial plaques. Their results suggest that the dual treatment also prevents the vessels from restarting their growth, which could shrink ... a substance that made them stick in growing blood vessels and with fumagillin, a potent compound that stops ...

ThromboGenics N.V. - Business Update

... that blocks the formation of the new blood vessels that are needed by solid tumours to support ... to competing agents, TB-403 only blocks blood vessels in tumour tissue and not in healthy tissue. This ... RESISTANT TUMORS WITHOUT AFFECTING HEALTHY vessels - Christian Fischer, Bart Jonckx, Massimiliano ...

European Regulatory Agency Supports OPAXIO(TM) Brand Name for Cell Therapeutics' Lung Cancer Drug

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing ...

Publication in Clinical Cancer Research Confirms Ability of Peregrine's Bavituximab to Target Tumor Blood Vessels with Excellent Specificity

... specificity of bavituximab to target tumor blood vessels with little or no localization to normal ... localized to the tumor blood vessels with great specificity. In these subjects, 22 ... evidence that bavituximab targets tumor blood vessels with excellent specificity," said Steven W. King, ...

Cell Therapeutics, Inc. (CTI) to Submit Marketing Authorization Application for XYOTAX(TM) for First-line Non-small Cell Lung Cancer Ahead of Schedule

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules like ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed ...

Presentation of Phase IIa Results for Cytos Biotechnology's Hypertension Vaccine at the American Heart Association Scientific Sessions 2007

... of blood pressure. Angiotensin II causes blood vessels to narrow, resulting in increased blood pressure. ... receptors and subsequent narrowing of blood vessels should be decreased. The RAS has already been ... of the RAS inducing vasoconstriction of blood vessels and other effects to raise blood pressure. ...

Cell Therapeutics, Inc. (CTI) Receives SPA Approval from FDA and Launches Gender-Specific Phase III Trial for Advanced Non-Small Cell Lung Cancer

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing ...

Cardica Receives European CE Mark for C-Port Flex A System for Use in Coronary Artery Bypass Surgery

... the automated anastomosis, or attachment of blood vessels and grafts, during less invasive coronary artery ... reliable and reproducible connections of blood vessels during CABG surgery. The C-Port Flex A system has ... is effective in creating compliant anastomoses in vessels as small as one millimeter in internal diameter; ...

Video: Axel Ullrich Named Winner of 2009 Dr. Paul Janssen Award for Biomedical Research

... system involved in regulating tumor angiogenesis, the growth of blood vessels in tumors. He discovered that inhibiting a key player in the signaling ... growth factor receptor or VEGFR) suppresses the generation of blood vessels in tumors and slows down cancer cell growth. Years later, a small molecule ...

Calvert Research Licenses Novel Technology to Treat Age Related Macular Degeneration from Tulane University

... (atrophic) and wet (exudative) form. Wet AMD occurs when abnormal blood vessels behind the retina begin to grow under the macula, often leaking blood and ... drug candidate designed to specifically target and kill abnormal blood vessels found in wet AMD patients. The lead compound from this technology ...

AngioGenex Presents Data on its Id Targeted Anti-Angiogenesis Inhibitors at Two Scientific Conferences

... either the Id genes or proteins to prevent the formation of new blood vessels into tumors (angiogenesis). The Company's technology is based on the ... that activation of the Id genes is required for the formation of new blood vessels into tumors, allowing tumors to grow and metastasize. Dr. Benezra ...

OmegaGenesis Announces Angiogenesis Application Collaboration

... spread of cancer and malignancies. In cancer and malignancies, new blood vessels feed the cancer cells with oxygen and nutrients, allowing these cells to ... the current limitation of therapy to create new functional blood vessels in ischemic diseases, this finding has significant potential for clinical ...

Spectrum Pharmaceuticals and Cell Therapeutics to Jointly Market ZEVALIN, a Proprietary, Marketed Oncology Drug

... blood cells and normally spreads through the lymphatic system, a system of vessels that drains fluid from the body. NHL can be broadly classified into two ... blood cells and normally spreads through the lymphatic system, a system of vessels that drains fluid from the body. NHL can be broadly classified into two ...

AngioGenex Reviews 2008 Achievements and Sets Goals for 2009

... either the Id genes or proteins to prevent the formation of new blood vessels into tumors (angiogenesis). The Company's technology is based on the ... that activation of the Id genes is required for the formation of new blood vessels into tumors, allowing tumors to grow and metastasize. Dr. Benezra ...

CorMatrix Announces Pre-Clinical Data Suggesting Next Generation ECM Technology(TM) Can Improve Cardiac Function

... enhanced, evidenced by increased density value of a-SMA-positive vessels (70+/-10 vs. 20+/-4/HPF) and vWF-positive vessels (95+/-14 vs. 34+/-8/HPF). At 42 days post reperfusion, echocardiography ...

FDA Approves Orphan Drug Status for Revolutionary Cancer Drug for Children

... formulation which allows the matter to migrate through the body's own vessels directly to the tumor cells. When the tumor cells uptake the matter, they ... cells -- The product is so small that it migrates right through blood vessels and cell walls -- This technology be applied to other diseases in the ...

33rd ESMO Congress in Stockholm, 12-16 September 2008

... 2008, 10:00 CEST) A new form of chemotherapy that destroys new blood vessels that grow around tumours has produced excellent results in a phase II ... drug that combats ovarian cancer by inhibiting the formation of new blood vessels has shown promise in a phase II trial, according to Prof. Michael ...

BugLab Launches Noninvasive Biomass Monitor for Continuous, On-Line Measurements

... to the outside of a variety of different fermentor types, from small glass vessels to large stainless steel vessels with glass viewing ports. Since no immersion port is required, it avoids ...

AngioGenex Appoints New CEO to Direct Development of Anti-Cancer Drugs

... either the Id genes or proteins to prevent the formation of new blood vessels into tumors (angiogenesis). The Company's technology is based on the ... that activation of the Id genes is required for the formation of new blood vessels into tumors, allowing tumors to grow and metastasize. Dr. Benezra ...

Peregrine Pharmaceuticals Presents Promising Phase I Data at ASCO and Provides Clinical Update on Its Phase II Bavituximab Breast Cancer Study

... helps mobilize the body's own immune system to attack tumors and the blood vessels supporting tumor growth and spread," said Dr. Raghunadharao Digumarti, ... but which becomes exposed on the outside of the cells that line the blood vessels of tumors, creating a specific target for anti-cancer treatments. By ...

ThromboGenics Completes Patient Enrolment of MITI IV Trial, a Phase II Study Evaluating the Safety and Preliminary Efficacy of Microplasmin in the Treatment of Acute Stroke

... About Stroke Stroke is a cardiovascular disease affecting the blood vessels of the brain. Stroke is caused by a blockage of the blood vessels of the brain, depriving the brain of oxygen, and can result in severe ...

Angiotech announces commercial launch of Cook Medical's Zilver(R) PTX(TM) drug-eluting peripheral stent in New Zealand

... Artery Disease (PAD) Peripheral Artery Disease (PAD) affects blood vessels that lead from the heart to other areas of the body, such as the legs, feet and kidneys. When the blood vessels become blocked due to the build-up of fatty deposits, blood circulation is ...

Vical Licensee AnGes MG Files NDA in Japan for Collategene Angiogenesis Product

... factor (HGF), a human protein that causes growth of blood vessels in areas of restricted blood flow. "The Japanese NDA filing positions ... which occurs by decreased blood flow caused by narrowing of blood vessels as a result of arteriosclerosis, and ischemic heart disease. This is a ...

Escalon(R) Announces FDA 510(K) Clearance for VascuView(TM) Visual Ultrasound System For Assisted Vascular Access

... -- Large image display providing easy visualization of targeted vessels and surrounding anatomy -- Touchscreen display with intuitive and ... vascular access assemblies, which are used to locate desired vessels for access. These patented devices utilize a miniature Doppler ultrasound ...

Cardica and Intuitive Surgical to Host Educational Symposium on 'Advanced Techniques and Technologies in Robotic Coronary Revascularization and Mitral Valve Repair'

... to enable automated, reliable and reproducible connections of blood vessels during CABG surgery. Unlike most hand-sewn anastomoses, Cardica's C-Port ... than rigid, shaft and is designed to create compliant anastomoses in vessels as small as one millimeter in internal diameter. Importantly, the flexible ...

Researchers use magnetism to target cells to animal arteries

... heart disease commonly receive metal stents in partially blocked blood vessels to improve blood flow, both by widening the vessels and delivering drugs. However, many stents fail over time as smooth muscle ...

JCI table of contents: Dec. 3, 2007

... a patients chances of survival are very poor. The functionality of small vessels feeding the transplanted organ is likely to play a key role in preventing ... to organ tissues, researchers examined the functionality of mouse blood vessels following tracheal transplants where surgical revascularization was not ...

ThromboGenics and BioInvent Announce Publication of Exciting Data on a Novel Class of Angiogenesis Inhibitors in Cell

... are due to PIGF inhibitors acting by blocking the formation of new blood vessels only in the cancer tissue. ThromboGenics and BioInvent have made the ... in diseased conditions, without, importantly, affecting normal blood vessels in healthy tissues. These findings pave the way for the development of a ...

On the road to a new cancer therapy -- starving the tumor

... growth factors. These growth factors stimulate the formation of blood vessels that feed the tumor cells. In this way, even the innermost part of the ... to develop new therapies for cancer. Indeed, when the formation of blood vessels that feed tumor cells is blocked, the tumor starves due to the lack of ...

Baxter Adds Recombinant Protein to Specialty Therapeutics Portfolio

... (TTP), marked by the formation of platelet-rich blood clots in blood vessels throughout the body. Recombinant ADAMTS13 is being developed for the ... that is caused by the formation of platelet- rich thrombi in blood vessels throughout the body. Hereditary TTP, also known as Upshaw Schulman ...

ChemoCentryx Demonstrates Recently Discovered Chemokine Receptor CXCR7 is Essential in Tumor Growth

... by both the malignant tumor cells and by the tumor-associated blood vessels in the tumor mass, but not found on healthy cells or normal vasculature ... strongly suggesting that CXCR7 is central to the formation of new blood vessels during development (a process known to resemble aspects of new blood ...

Study Published in Clinical Cancer Research Confirms Potential Of Peregrine's Bavituximab Combined With Radiation In Lung Cancer

... may have contributed to the finding that the density of tumor blood vessels was reduced by more than 90% and tumor growth was reduced by 80% in ... is believed to help mobilize the body's immune system to destroy the blood vessels needed for tumor growth and spread. In a Phase lb trial in advanced cancer ...

ThromboGenics - Business Update and Interim Results for the Seven Month Period Ending 30 June 2007

... is a humanized monoclonal antibody that blocks the formation of new blood vessels in solid tumors. By blocking the formation of new blood vessels (anti-angiogenesis), TB-403 has the potential to reduce the growth and ...

Angiotech Pharmaceuticals, Inc. announces financial results for the second quarter ended June 30, 2009

... stent system, a next-generation paclitaxel-eluting stent specifically designed for treating small coronary vessels. It was approved for use in vessels as small as 2.25 mm in diameter and joins the TAXUS Express Atom(TM) stent as the only drug-eluting stents ("DES") approved for small vessel use in ...

PTC Therapeutics Initiates Phase 2 Clinical Trial of PTC299 in Patients with Neurofibromatosis Type 2

... of VEGF. (Logo: http://www.newscom.com/cgi-bin/prnh/20010919/PTCLOGO ) VEGF plays a critical role in the formation of new blood vessels or angiogenesis and its suppression has been shown to decrease tumor size and improve hearing in some patients with NF2. PTC299 selectively blocks ...

Study Published in Child and Adolescent Psychiatry and Mental Health Demonstrated Once-Daily Vyvanse(R) (lisdexamfetamine dimesylate) CII Provided Significant Improvement of ADHD Symptoms for Children at 13 Hours After Administration

... suggest heart problems, such as chest pain or fainting. Vyvanse should not be taken if you or your child has advanced disease of the blood vessels (arteriosclerosis); symptomatic heart disease; moderate to severe high blood pressure; overactive thyroid gland (hyperthyroidism); known allergy or ...

Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost

... cost of failure are both great. "Unlike a long range missile, the millions of shipping containers that are used to transport goods in ocean-going vessels provide terrorists with a way to hide a nuclear device destined for U.S. shores," they write. "Further, by using a container, terrorists can ...

Study Showed VYVANSE(R) (lisdexamfetamine dimesylate) CII Provided Significant Efficacy at 14 Hours After Administration in Adults with ADHD in an Adult Simulated Workplace Environment

... that suggest heart problems, such as chest pain or fainting. Vyvanse should not be taken if you or your child has advanced disease of the blood vessels (arteriosclerosis); symptomatic heart disease; moderate to severe high blood pressure; overactive thyroid gland (hyperthyroidism); known allergy or ...
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