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Saturation in Biological Technology

Five New Clinical Studies Show Value of Masimo PVI & PI

... earlier, and more effectively manage blood transfusions. While oxygen saturation (SpO2) and hemoglobin are considered critical parameters for patient ... performance of Masimo SET(R) Oxygen saturation (SpO2), Pulse Rate (PR) and Perfusion Index (PI). About Masimo Masimo ...

Masimo Reports Second Quarter 2007 Financial Results

... and neonates. The Rainbow sensors are capable of measuring not only oxygen saturation (SpO2), Pulse Rate and Perfusion Index, but also, carboxyhemoglobin ... Masimo SET technology allows clinicians to accurately monitor blood oxygen saturation in critical care situations. Our Masimo SET platform has significantly ...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... should be discussed and the need for contraception evaluated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron ...

Spectros T-Stat Tissue Oximeter Clinical Studies Presented at PAS (Pediatric Academic Societies') Conference

... PRBC Transfusion in Very Low Birth Weight (VLBW) Neonates." The authors noted, "VLS is an easy to use and noninvasive method of assessment of tissue saturation in VLBW neonates with various severity of illness." The second poster was titled, "Noninvasive Measurements of Plasma Bilirubin Levels Using ...

InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF

... from Baseline to Week 72 in the percent predicted Hb-corrected DL(CO) 6. Change from Baseline to Week 72 in the worst oxygen saturation by pulse oximetry (SpO2) measurement observed during the Six-Minute Walk Test 7. Change from Baseline to Week 72 in ...

New Multi-Center Study Finds Masimo SET Pulse Oximetry Screening Significantly Improves Detection of Congenital Heart Disease in Newborns

... born between 2004 and 2007 at five well baby nurseries using Masimo SET pulse oximetry. A positive pulse oximetry result was defined as an oxygen saturation of <95% measured both preductally (right hand) and postductally (either foot), or a measurement difference >3% between the two measurements. ...

Capture of nanomagnetic 'fingerprints' a boost for next-generation information storage media

... nanodisks. Then they applied a series of magnetic fields to the wires and measured the responses from the nanodisks. By starting each cycle at full saturation that is, using a field strong enough to align all the nanomagnets then applying a progressively more negative field with each reversal, they ...

New Clinical Studies Presented at the American Society of Anesthesiology (ASA) Annual Meeting Show Masimo Technologies Provide Advanced Clinical Intelligence

... a clinical study led by Dr. Mitchell R. Goldstein at Loma Linda Children's Hospital in Loma Linda, California, evaluated whether methemoglobin saturation (SpMet(TM)) could be successfully measured in neonates without compromise in oxygen saturation (SpO2) accuracy. Researchers compared noninvasive ...

Masimo Initiates Limited Release of First-Ever Noninvasive and Continuous Hemoglobin Monitors

... clearance of its latest Rainbow family of adhesive sensors capable of noninvasively measuring total hemoglobin and oxygen content, along with oxygen saturation (SpO2), pulse rate, pleth variability index (PVI), and methemoglobin (SpMet(R)), for use with Masimo Rainbow SET-enabled devices. The limited ...

Masimo Announces Desaturation Index 3D Alarm as Standard Feature in All Radical-7 Pulse CO-Oximetry Devices

... now receive Desat Index 3D Alarm as a standard feature. Conventional pulse oximeters typically alarm based on large and isolated drops in oxygen saturation values, known as a "desaturation". However, published research has shown that a cycle of moderate desaturations has been shown to precede respiratory ...

SPO Medical Reports First Quarter 2008 Results

... 6100(TM) (hand-held device). Both products use Reflective Pulse Oximetry (RPO) technology for accurate and reliable measurements of blood oxygen saturation and heart rate. In addition, these devices utilize the new SPO Medical AutoSpot(TM) technology for accurate measurements even with patients that ...

The Recession List - Top 10 Industries to Fly and Flop in 2008

... this year and 2012, we believe that industry revenue will increase by 56 percent as Internet penetration still has some way to go to reach full saturation in American households," said Mr. Van Horn. "Furthermore, broadband services will account for an ever increasing share of domestic Internet users, ...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa)

... be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron ...

Surface dislocation nucleation: Strength is but skin deep at the nanoscale, Penn engineers discover

... 10-50 nanometers for most metals. For comparison, computers now contain microchips with 45 nanometer strained silicon features. Associated with this saturation in strength is a transition in the rate-controlling mechanism, from collective dislocation dynamics to single dislocation nucleation. ...

Ortho Biotech Statement On JAMA Publication Regarding Erythropoiesis-Stimulating Agents

... be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron ...

SPO Medical Begins Shipping PulseOx 6000(TM) and PulseOx 6100(TM)

... the PulseOx 6000(TM) and PulseOx 6100(TM) use Reflective Pulse Oximetry (RPO) technology for accurate and reliable measurements of blood oxygen saturation and heart rate. In addition, these devices utilize the new SPO Medical AutoSpot(TM) technology for accurate measurements even with patients that ...

Nonin Medical, Inc. Receives Frost & Sullivan's 2007 Award for Product Differentiation Innovation

... more people and applications worldwide. "Nonin's PureSAT(R) signal processing and PureLight(R) sensor technologies offer unparalleled blood oxygen saturation level recording and analysis by eliminating the effect of low perfusion and motion artifacts," said the Frost & Sullivan report. With its patented ...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa) Label Reflects Recommendations from Recent FDA Advisory Committee Meetings

... be discussed and the need for contraception evaluated. * Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron ...

Ortho Biotech Supports FDA Advisory Committees' Recommendations on Use of ESAs in Chronic Renal Failure Patients

... be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron ...

Apria Healthcare Chooses Masimo SET Pulse Oximetry for Use in the Company's Home Health Care Business

... proven in more than 100 independent clinical and laboratory studies to provide the most trustworthy continuous noninvasive arterial blood oxygen saturation and pulse rate measurements even under the most difficult clinical conditions, including patient motion and low peripheral perfusion. These studies ...

Development of Radioligand Binding Assays for the Motilin Receptor Using ScreenReady Targets.

... Results and Discussion saturation Binding Assays Membranes from CHO cells ... [ 125 I]-motilin for the receptor was determined. saturation experiments using motilin ScreenReady Targets ... high affinity binding sites was detected from the saturation experiment performed on the day of membrane ...

Detection of Phosphorylated and Total ERK and p38 MAPK by Bio-Plex Assay, ELISA, and Western Blotting, Rev A

... 1B). The data also suggest high-end saturation over 10 g/well. With the western blot, ... (Figure 2A). The ELISA displayed a high-end saturation plateau in samples with a protein ... blot. The Bio-Plex assay showed saturation at the high end but potential to detect the ...

Quantitation of Cabergoline at Extremely Low Plasma Concentrations with a Triple Quadrupole Mass Spectrometer

... to be nonlinear and/or for detector saturation to occur for linear dynamic ranges as low as 3 ... concentration analyte, sacrificing detector saturation of the higher concentration analytes. Since ... for applications where detector saturation is typically encountered. The broad dynamic ...

Development of a histamine H1 receptor binding assay using the LEADseeker Multimodality Imaging System

...

Results K d determination saturation binding was performed with dilutions of [ pyridinyl -5- 3 H]Pyrilamine to ... h at room temperature and in darkness prior to imaging. Figure 1 shows the saturation curve, which was fitted using non-linear regression with the data analysis ...

The development of a melanocortin MC4 receptor binding assay using the LEADseeker Multimodality Imaging System

...

Results K d determination saturation binding was carried out with dilutions of [ 125 I] NDP-α-MSH to give ... from 4.05 pM to 10.43 nM in the assay wells. Figure 1 shows the saturation curve which was fitted using non-linear regression with the data analysis ...

Keys to Successful Densitometry

... an image for integrated density determinations, the user must keep the saturation Warning function of the View menu enabled to avoid saturating pixels within bands or spots of interest. Enabling the saturation Warning function results in image pixels with values of 255 to be ...

The flattening world and its impact on U.S. biotech

... these by foreign countries, is leading toward a global registration dossier that would allow registration in many countries at the same time. The saturation of the U.S. patient population for clinical trials is driving the performance of these trials off-shore, where patients can be found faster and ...

Sonic Foundry reports first cash-positive quarter

... and distance learning markets and the estimated 25 million rooms that need LCD projectors - analysts believe that the company is nowhere near market saturation and very near early stage in terms of market potential. The math is maybe too big to be believable, Buinevicius said. Perhaps the best ...

Rapamycin Optimized in 100 Liter Fermentor Using BioCommand Control Strategys

... altering setpoints on the basis of time or metabolic events. In this study, AFS-BioCommand was programmed to maintain a D.O. level of 30% of air saturation by automatically increasing agitation rates from 200 to 450 rpm, then vessel pressure from 0.35 to 0.75 bar, aeration rate from 0.5 to 1 VVM and ...

FERMENTATION BASICS

... rate or o xygen absorption rate which permits respiration without hindrance. Generally the critical oxygen concentrations are 5-25% of the oxygen saturation value in cultures. At oxygen absorption rates which are lower than the critical concentrations, respiration rate is correlated with the O 2 ...

New statistical algorithms for Monitoring Gene Expression on GeneChip® Probe Arrays

... gives a nearly 10% greater fraction of correct Increase calls than does MAS 4.0. The drop in accuracy seen at very high concentration is due to the saturation of probe sets by the vast excess of spiked transcripts. To understand the difference in the performance of calls generated by MAS 4.0 and ...

Coated Plate Immunoassay on the MicroBeta - eg. TSH - IRMA

... Wash 3 x with the wash solution 6. Saturate 1 hour at room temperature with 200 μL of 50 mM TSA-buffer containing 0.5% BSA saturation Buffer formulation: 50 mM Tris = 0.606 g Tris (Sigma) 0.9% NaCl = 0.9 g conc HCl 0.30 mL 7.5% BSA ...

Use of FlashPlate Technology for In Vitro Measurement of 125I-Labeled TGF-1 Binding on Chimeric Extracellular Domain of Type II Transforming Growth Factor Receptor

... receptor secreted by Cos-7 cells was able to effectively bind 125 I-labeled TGF-1 (Figure 1). The Protein A FlashPlate assay showed a typical saturation curve of TGF-1 binding to hTRIIs-Fc (Figure 2). The kinetics of 125 I-labeled TGF-1 binding, performed at room temperature, were relatively rapid, ...

Small-Molecule Quantitation Using Automated Single-Shot Averaging MALDI-TOF Mass Spectrometry

... mode. The spectra were evaluated and averaged in the following manner: The laser power was automatically adjusted to ensure no saturation of the analyte or internal standard peaks (Figure 1). Evaluation of single-shot mass spectra for averaging was done automatically by the acquisition ...

Development of a CRF1 neuropeptide receptor binding assay using LEADseeker Multimodality Imaging System

... binning.

Results K d determination saturation binding was performed with dilutions of [ 125 I]Tyr 0 -CRF to give a range of concentrations from 0.06 to 4.96 nM in the wells. Figure 1 shows the saturation curve, which was fitted using non-linear regression with the data analysis ...

Development of an adrenergic α2a receptor binding assay using the LEADseeker Multimodality Imaging System

...

Results K d determination saturation binding was performed with dilutions of [0-methyl- 3 H]Rauwolscine to give ... wells. Plates were incubated for 5 h prior to imaging. Figure 1 shows the saturation curve, which was fitted using nonlinear regression with the data analysis ...

The development of a serotonin 5-HT2C receptor-binding assay using the LEADseeker Multimodality Imaging System

... 3 binning. Results K d determination saturation binding was performed with dilutions of [ 3 H]Mesulergine to give a range of concentrations from 30 nM to 1.18 pM in the wells. The saturation curve (Fig 1) was fitted using non-linear regression with the data ...

The development of a somatostatin sst4 receptor-binding assay using the LEADseeker Multimodality Imaging System

...

Results K d determination saturation binding was carried out with dilutions of (3-[ 125 I] iodotyrosyl 11 ) ... of concentrations from 0.0 0347–3.00 nM in the assay wells. The saturation curve (Fig 1) was fitted using non-linear regression with the data ...

Development of an NK2 neuropeptide receptor binding assay using LEADseeker Multimodality Imaging System

...

Results K d determination saturation binding was performed with dilutions of [ 125 I]NKA to give a range of concentrations from 0.01 to 1.34 nM in the wells. Figure 1 shows the saturation curve, which was fitted using non-linear regression with the data analysis ...

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