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Rabbit in Biological Technology

Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R)

... animal model known as the New Zealand White (NZW) rabbit model. Valortim is a fully human monoclonal ... Inhalation Anthrax in the New Zealand White (NZW) rabbit Model" at the 48th ICAAC/ IDSA 46th Annual ... to attempt to refine the New Zealand White (NZW) rabbit model as a predictive therapeutic model for ...

Epitomics Announces the Creation of 1000th Rabbit Monoclonal Antibody

... today that it has developed its 1000th new rabbit monoclonal antibody. Each antibody has been ... QC'd in house utilizing Epitomics' proprietary rabbit monoclonal antibody technology. "We are very ... of the targets for which we have developed a rabbit Monoclonal, no other monoclonal antibody ...

Epitomics Appoints Dr. Zhiqiang An as Chief Scientific Officer

... /PRNewswire/ -- Epitomics, Inc., the world's sole provider of humanized rabbit monoclonal antibodies for therapeutic use, today announced the appointment ... maker of RabMAb(R) monoclonal antibodies, is the commercial supplier of rabbit monoclonal antibodies, with customers around the world, including major ...

IIVS Announces Initiation by EPA of a Pilot Program to Evaluate Non-Animal Eye-Irritation Methods

... approach." The goal of the EPA's pilot program is to evaluate the effectiveness of a non-animal testing method to replace the current Draize rabbit eye test. This approximately 18-month project encompasses the use of three in vitro assays: the Bovine Corneal Opacity and Permeability test (the use ...

Simcere Pharmaceutical Group Reports Unaudited First Quarter 2009 Results

... was primarily due to the recognition of an upfront payment to Epitomics Inc. under the agreement for the co-development and production of humanized rabbit monoclonal antibody therapeutics for multiple tumors. As a percentage of total revenue, research and development expenses were 5.7% for the first ...

Assay Designs(TM), Inc. Announces Agreement with Abnova Corp. of Taiwan

... Abnova's mission is to be the world's largest antibody distributor. They have the capacity of generating 500 mouse monoclonal antibodies and 500 rabbit polyclonal antibodies per month. "We are very pleased to be collaborating with Assay Designs on broadening the exposure and accessibility of Abnova ...

Elusys' Anthim(TM) Dramatically Improves Survival of Animals Treated After Active Anthrax Infection

... (75% survival) when administered at the onset of clinical symptoms of disease (24 hr. post exposure). These results are consistent with a recent rabbit study that showed significant survival of animals treated 24 hours after infection when bacteremia was present. Elizabeth Posillico, Ph.D., ...

3SBio Inc. Announces Unaudited Fourth Quarter and Fiscal Year 2007 Results

... monoclonal antibody (mAb) in development, anti-TNF mAb (SSS07), completed characterization of fully humanized clones, and the original potency of the rabbit mAb proved to be more advantageous than all known anti-TNF mAbs currently on the market. Sales and Marketing. In the fourth quarter 2007, we ...

Ferring Pharmaceuticals Announces EUFLEXXA(TM) as Title Sponsor of the National Senior Games Hockey Championships and the GeezerJock of the Year Award

... G (2002). Comparison of the effects of intra-articular injections of Hyaluronan and its chemically cross-linked derivative (Hylan G-F20) in normal rabbit knee joints. Clin Exp Rheumatol 20, 445-454. 3 Goomer RS, Leslie K, Maris T, & Amiel D (2005). Native hyaluronan produces less hypersensitivity ...

Targanta Therapeutics to Have Significant Presence at 47th Annual ICAAC Meeting

... In Vivo Efficacy of a New Sept. 19 10:15AM Osteotropic Prodrug in a CDT rabbit Model of Chronic Osteomyelitis 10:15AM- B-1357 Slide Tanaka Preparation and In ...

An entrepreneurial success story Frank Langley champions biocapitalism

... during the World Wars because unlike other meats, rabbit meat was not rationed. As time went on, Pel-Freez rabbit Meat, Inc. relocated to Rogers, Arkansas, because ... realized that the by-products from processing rabbit meat things ...

The IT drug Just say no?

... of most modern IT projects. The business-like rabbit rushing by, very late for a very important date, ... just out of reach around the next turn of the rabbit hole or opportunity, and unavailable for any ... starts with how we respond the next time that rabbit runs by or some shrink-wrapped wonder drops on ...

Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods

... in the seventies and replaces more and more the rabbit pyrogenic test which was used since ... has to be checked. The advantage of the rabbit test (Ph. Eur. 2002, 2.6.8) is that all known ... can be better standardized than the rabbit test. Moreover, it allows a quantitative ...

Quantitation of Oxybutynin in Rabbit Plasma Using the Varian 1200L LC/MS/MS System

... absorption through the urethra. Using a rabbit model, urethral suppositories, formulated with ... Preparation A 0.5 mL aliquot of rabbit EDTA plasma containing oxybutynin chloride is ... is generated from the analysis of a drug free rabbit plasma matrix fortified with various amounts of ...

Multiplex protein detection with the ECL Plex fluorescent Western blotting system using the Ettan DIGE Imager

... A3653 rabbit polyclonal anti–human transferrin ... (Thr180/Tyr182) Antibody, rabbit (Cell Signaling) 10x PBS ...

The blots were then incubated with the rabbit anti–human transferrin or the mouse ...

Quantitative Analysis of Protein-DNA Associations in Vivo Using Real-Time PCR, Rev A

... sample immunoprecipitated with normal rabbit serum. Fold differences (Pdx1 ChIP ... immunoprecipitated with normal rabbit serum and NIH 3T3/EV chromatin immunoprecipitated with Pdx1 antiserum or normal rabbit serum). This finding (ΔΔC T = 3) ...

Delivery of pCMV-S DNA Using the Helios Gene Gun System Is Superior to Intramuscular Injection in Balb/c Mice

... hr. Following five more washes, 100 l of 1:1,000 rabbit anti-mouse-HRP (Serotec Ltd, Oxford, ... as described above with the exception that the rabbit anti-mouse HRP antibody was replaced ... a 96-well plate was coated with 50 l of 1:1,000 rabbit anti-mouse immunoglobulins (Dako, Ely, ...

Enzyme Immunoassay for Studying Intracellular Levels of cAMP

... conjugate that binds to rabbit anti-cAMP-specific antibodies. ... precoated with goat anti-rabbit IgG. rabbit anti-cAMP antibodies are combined with ... a fixed quantity of tracer for the rabbit anti-cAMP-specific antibodies. All unbound ...

Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies

... a colloidal-gold conjugation technique to label rabbit anti-mouse l and k light chain antibodies as indicating reagents, and rabbit anti-mouse isotyping immunoglobulin ... a complex containing mouse immunoglobulin and rabbit anti-mouse l or k gold-conjugated ...

Utilization of Donkey Anti-Rabbit PS SPA Imaging Beads in the quantitative measurement of cAMP in cells

... Beads coated with donkey anti-rabbit antibody enable the immobilization of rabbit secondary antibodies during the assay. The Donkey Anti-Rabbit PS SPA ... methyl ester, 147.5 kBq, 4 µCi, lyophilized. rabbit anti-succinyl cAMP serum, lyophilized. Lysis reagent 1 ...

OpGen Database Helps to Reduce Bioterrorist Threat

... mapping of DNA. One of the most infectious bacteria, Francisella tularensis, is a causative agent of Tularemia, a disease often referred to as rabbit or deer fever. The bacterium is naturally found in rodents, rabbits and hares in the United States. If F. tularensis was used as an airborne ...

The Year Ahead in IT

... activity in the first quarter as firms try to put to work uninvested money before the end of the fund's term. There's just not enough time to pull a rabbit out of the hat, however, and venture capitalists in all but the top tier are in for a world of hurt. 3. Expect the re-emergence of the Consumer ...

Why are new drugs failing?

... Running of animal cardio tox tests in a relatively cost-effective manner versus traditional cardio tox studies The isolated heart model uses a rabbit heart model to determine the effects of new drugs on coronary vasculature and cardiovascular pump function. CorDynamics looks at the left ventricular ...

The Croquet Project: An open source solution to the OS monopoly

... they were making the Internet do its job differently. They opened with a 3-D courtyard dubbed the "Cirque du Croquet." Using avatars of the White rabbit and Alice Little, Lombardi and Austin moved through the environment to show off some of the qualities of Croquet. Inside the system, each avatar can ...

DNA Damage and Repair - Quantification of Sub-Cellular Events Using Automated Confocal Imaging

... monoclonal anti-phospho serine 139 H2AX antibody (Chemicon, 05-636) at 2 μg/mL in 1% BSA block was used. 53BP1 was detected using the anti-53BP1 rabbit polyclonal antibody (Novus Biologicals, NB 100-304) diluted as described for H2AX. After 1h at room temperature, the primary antibody was ...

Caspase-3 Activation - An Indicator of Apoptosis in Image-Based Assays

... binding was blocked for 1h with 5% goat serum in PBS buffer containing 0.3% Triton X-100. Cells were then incubated with cleaved caspase-3 (Asp 175) rabbit polyclonal antibody (Cell Signaling Technology, 9661, 1:100 dilution) in 5% goat serum and 0.3% Triton X-100 over night at 4C. Further wash steps ...

Apoptosis detection by annexin V and active caspase-3 with the Agilent 2100 bioanalyzer

... BD FACS Permeabilizing Solution 2 (500 tests) Camptothecin: Prepare a 10 mM solution in DMSO. rabbit anti-active caspase-3 mAb Cy5-conjugated AffiniPure F(ab')2 fragment goat anti-rabbit IgG (H+L) SYTO16 Staining ...

EndoFree Plasmid Kits

... EndoFree DNA yields high transfection efficiencies with primary cells Primary rabbit gastric parietal cells were transfected with pEGFP-N2 (CLONTECH) prepared by the methods indicated. Transfections were performed ...

Effectene Transfection Reagent

... Effectene Reagent with Primary Cells Expression of green fluorescent protein (GFP) in primary rabbit aortic smooth muscle cells transfected using Effectene Reagent. 1 x 105 cells were seeded one day prior to transfection, and ...

Detect Released Oligosaccharides Using the Eagle Eye II Still Video Imaging System

... profiling kit. Transferrin, fetuin, and carboxypeptidase Y were taken from Boehringer Mannheims DIG Glycan Differentiation kit. The rabbit polyclonal antibody (IgG) was raised against human P-glycoprotein in our lab. Sample proteins were treated with PNGase F (Bio-Rad kit) to release ...

Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling

... previously, it has been used as a marker for synapse formation and elimination. 8 Stratagene introduces an affinity-purified rabbit polyclonal synapsin antibody, Anti-Synapsin I, that can be used for studying synapsin expression in different cell types and brain ....
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