Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R)
... animal model known as the New Zealand White (NZW) rabbit
Valortim is a fully human monoclonal ... Inhalation
Anthrax in the New Zealand White (NZW) rabbit
Model" at the 48th ICAAC/
IDSA 46th Annual ... to attempt to refine the New Zealand White (NZW) rabbit
model as a
predictive therapeutic model for ...
Epitomics Announces the Creation of 1000th Rabbit Monoclonal Antibody
... today that it has developed its
1000th new rabbit
monoclonal antibody. Each antibody has been ... QC'd in house utilizing Epitomics' proprietary rabbit
antibody technology. "We are very ... of the targets for which
we have developed a rabbit
Monoclonal, no other monoclonal antibody ...
Epitomics Appoints Dr. Zhiqiang An as Chief Scientific Officer
... /PRNewswire/ -- Epitomics, Inc., the world's sole provider of humanized rabbit
monoclonal antibodies for therapeutic use, today announced the appointment ... maker of RabMAb(R) monoclonal antibodies, is the commercial supplier of rabbit
monoclonal antibodies, with customers around the world, including major ...
IIVS Announces Initiation by EPA of a Pilot Program to Evaluate Non-Animal Eye-Irritation Methods
The goal of the EPA's pilot program is to evaluate the effectiveness of a non-animal testing method to replace the current Draize rabbit
eye test. This approximately 18-month project encompasses the use of three in vitro assays: the Bovine Corneal Opacity and Permeability test (the use ...
Simcere Pharmaceutical Group Reports Unaudited First Quarter 2009 Results
... was primarily due to the
recognition of an upfront payment to Epitomics Inc. under the agreement for
the co-development and production of humanized rabbit
therapeutics for multiple tumors. As a percentage of total revenue, research
and development expenses were 5.7% for the first ...
Assay Designs(TM), Inc. Announces Agreement with Abnova Corp. of Taiwan
... Abnova's mission is to be the world's largest antibody distributor.
They have the capacity of generating 500 mouse monoclonal antibodies and
polyclonal antibodies per month. "We are very pleased to be
collaborating with Assay Designs on broadening the exposure and
accessibility of Abnova ...
Elusys' Anthim(TM) Dramatically Improves Survival of Animals Treated After Active Anthrax Infection
... (75% survival) when administered at
the onset of clinical symptoms of disease (24 hr. post exposure). These
results are consistent with a recent rabbit
study that showed significant
survival of animals treated 24 hours after infection when bacteremia was
Elizabeth Posillico, Ph.D., ...
3SBio Inc. Announces Unaudited Fourth Quarter and Fiscal Year 2007 Results
... monoclonal antibody (mAb) in development, anti-TNF
mAb (SSS07), completed characterization of fully humanized clones, and the
original potency of the rabbit
mAb proved to be more advantageous than all
known anti-TNF mAbs currently on the market.
Sales and Marketing. In the fourth quarter 2007, we ...
Ferring Pharmaceuticals Announces EUFLEXXA(TM) as Title Sponsor of the National Senior Games Hockey Championships and the GeezerJock of the Year Award
... G (2002).
Comparison of the effects of intra-articular injections of Hyaluronan and
its chemically cross-linked derivative (Hylan G-F20) in normal rabbit
joints. Clin Exp Rheumatol 20, 445-454.
3 Goomer RS, Leslie K, Maris T, & Amiel D (2005). Native hyaluronan
produces less hypersensitivity ...
Targanta Therapeutics to Have Significant Presence at 47th Annual ICAAC Meeting
... In Vivo Efficacy of a New Sept. 19 10:15AM Osteotropic Prodrug in a CDT rabbit
Model of Chronic Osteomyelitis
10:15AM- B-1357 Slide Tanaka Preparation and In ...
An entrepreneurial success story Frank Langley champions biocapitalism
... during the World Wars because unlike other meats, rabbit
meat was not rationed. As time went on, Pel-Freez rabbit
Meat, Inc. relocated to Rogers, Arkansas, because ... realized that the by-products from processing rabbit
meat things ...
The IT drug Just say no?
... of most modern IT projects.
The business-like rabbit
rushing by, very late for a very important date, ... just out of reach around the next turn of the rabbit
hole or opportunity, and unavailable for any ... starts with how we respond the next time that rabbit
runs by or some shrink-wrapped wonder drops on ...
Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods
... in the seventies and replaces more and more the rabbit
which was used since ... has to be checked.
The advantage of the rabbit
test (Ph. Eur. 2002, 2.6.8) is that all known
... can be better
standardized than the rabbit
test. Moreover, it allows a quantitative
Quantitation of Oxybutynin in Rabbit Plasma Using the Varian 1200L LC/MS/MS System
... absorption through the urethra.
Using a rabbit
model, urethral suppositories, formulated with ... Preparation
A 0.5 mL aliquot of rabbit
EDTA plasma containing oxybutynin chloride is ... is generated from the analysis of a drug free rabbit
plasma matrix fortified with various amounts of ...
Multiplex protein detection with the ECL Plex fluorescent Western blotting system using the Ettan DIGE Imager
polyclonal anti–human transferrin ...
10x PBS ...
The blots were then incubated with the rabbit anti–human transferrin or the mouse ...
Quantitative Analysis of Protein-DNA Associations in Vivo Using Real-Time PCR, Rev A
sample immunoprecipitated with normal rabbit
serum. Fold differences (Pdx1
ChIP ... immunoprecipitated with normal
serum and NIH 3T3/EV chromatin immunoprecipitated with Pdx1 antiserum
or normal rabbit
serum). This finding (ΔΔC T = 3)
Delivery of pCMV-S DNA Using the Helios Gene Gun System Is Superior to Intramuscular Injection in Balb/c Mice
... hr. Following five more washes, 100 l of 1:1,000 rabbit
anti-mouse-HRP (Serotec Ltd, Oxford, ... as described above with the exception that the rabbit
anti-mouse HRP antibody was replaced ... a 96-well plate was coated with 50 l of 1:1,000 rabbit
immunoglobulins (Dako, Ely, ...
Enzyme Immunoassay for Studying Intracellular Levels of cAMP
... conjugate that binds
with goat anti-rabbit IgG. rabbit
anti-cAMP antibodies are combined with
... a fixed quantity
of tracer for the rabbit
anti-cAMP-specific antibodies. All unbound ...
Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies
... a colloidal-gold conjugation technique to label rabbit
l and k light chain
antibodies as indicating reagents, and rabbit
anti-mouse isotyping immunoglobulin
... a complex containing mouse immunoglobulin and rabbit
l or k gold-conjugated ...
Utilization of Donkey Anti-Rabbit PS SPA Imaging Beads in the quantitative measurement of cAMP in cells
... Beads coated with donkey anti-rabbit antibody enable the immobilization of rabbit
secondary antibodies during the assay. The Donkey Anti-Rabbit PS SPA ... methyl ester, 147.5 kBq, 4 µCi, lyophilized.
anti-succinyl cAMP serum, lyophilized.
Lysis reagent 1 ...
OpGen Database Helps to Reduce Bioterrorist Threat
... mapping of DNA.
One of the most infectious bacteria, Francisella tularensis, is a causative agent of Tularemia, a disease often referred to as rabbit
or deer fever. The bacterium is naturally found in rodents, rabbits and hares in the United States. If F. tularensis was used as an airborne ...
The Year Ahead in IT
... activity in the first quarter as firms try to put to work uninvested money before the end of the fund's term. There's just not enough time to pull a rabbit
out of the hat, however, and venture capitalists in all but the top tier are in for a world of hurt.
3. Expect the re-emergence of the Consumer ...
Why are new drugs failing?
Running of animal cardio tox tests in a relatively cost-effective manner versus traditional cardio tox studies
The isolated heart model uses a rabbit
heart model to determine the effects of new drugs on coronary vasculature and cardiovascular pump function. CorDynamics looks at the left ventricular ...
The Croquet Project: An open source solution to the OS monopoly
... they were making the Internet do its job differently. They opened with a 3-D courtyard dubbed the "Cirque du Croquet."
Using avatars of the White rabbit
and Alice Little, Lombardi and Austin moved through the environment to show off some of the qualities of Croquet. Inside the system, each avatar can ...
DNA Damage and Repair - Quantification of Sub-Cellular Events Using Automated Confocal Imaging
... monoclonal anti-phospho serine 139 H2AX antibody (Chemicon, 05-636) at 2 μg/mL in 1% BSA block was used. 53BP1 was detected using the anti-53BP1 rabbit
polyclonal antibody (Novus Biologicals, NB 100-304) diluted as described for H2AX.
After 1h at room temperature, the primary antibody was ...
Caspase-3 Activation - An Indicator of Apoptosis in Image-Based Assays
... binding was blocked for 1h with 5% goat serum in PBS buffer containing 0.3% Triton X-100. Cells were then incubated with cleaved caspase-3 (Asp 175) rabbit
polyclonal antibody (Cell Signaling Technology, 9661, 1:100 dilution) in 5% goat serum and 0.3% Triton X-100 over night at 4C. Further wash steps ...
Apoptosis detection by annexin V and
active caspase-3 with the Agilent 2100
BD FACS Permeabilizing
Solution 2 (500 tests)
Camptothecin: Prepare a
10 mM solution in DMSO.
anti-active caspase-3 mAb
F(ab')2 fragment goat anti-rabbit
EndoFree Plasmid Kits
... EndoFree DNA yields high transfection
efficiencies with primary cells
gastric parietal cells were transfected with pEGFP-N2
(CLONTECH) prepared by the methods indicated. Transfections were performed
Effectene Transfection Reagent
... Effectene Reagent with Primary Cells
Expression of green fluorescent protein (GFP) in primary rabbit
smooth muscle cells transfected using Effectene Reagent. 1 x 105 cells
were seeded one day prior to transfection, and ...
Detect Released Oligosaccharides Using the Eagle Eye II
Still Video Imaging System
kit. Transferrin, fetuin, and carboxypeptidase Y were taken from Boehringer
Mannheims DIG Glycan Differentiation kit. The rabbit
(IgG) was raised against human P-glycoprotein in our lab. Sample proteins were
treated with PNGase F (Bio-Rad kit) to release ...
Antibodies for Studying NMDA Receptor Protein Expression and
... previously, it has been used as a marker for synapse formation
and elimination. 8 Stratagene introduces an affinity-purified
polyclonal synapsin antibody, Anti-Synapsin I, that can be used
for studying synapsin expression in different cell types and brain ....