Science Fuels DNA Testing Controversy with Prejudicial Misquote
... -- Hospitalized psychiatric patients who are poor
metabolizers cost $4,000 - $6,000 more in ... by enzymes with a high incidence of poor
metabolizers. Journal of Clinical ... processed by enzymes with genes known to have poor
metabolizer variants. This is compared to ...
OncoGenex reports lead drug candidate OGX-011 achieved primary endpoint in Phase 2 Trial with second-line chemotherapy for prostate cancer
... Patients in
this study represented a poor
prognostic population due to rapid ... to disease progression,
treatment resistance, poor
prognosis and survival in ... score, which is a
strong prognostic factor for poor
survival of patients with prostate
Patton Medical Devices Partners With Unomedical to Develop and Market the i-port Advance(TM) Injection Port for People Taking Multiple Daily Injections
... risks when using the i-port(R) include infection and the potential for poor
medication delivery if not properly applied. For people with diabetes, the poor
medication delivery may result in abnormally high or low blood sugar ...
Neurim Pharmaceuticals Reports Long Term Efficacy and Safety for Circadin(R) for Insomnia in Elderly Patients
... Health for the short-term treatment of primary
insomnia, characterized by poor
quality of sleep in patients who are aged 55
and over. The approval is ... Circadin(R), previously
shown to be a unique short term treatment for poor
sleep quality, has now
demonstrated long term efficacy and safety."
Disability and Poor Quality of Life Associated With Treatment Failure Gout Patients
... patients ."
Treatment failure gout was shown to be associated with poor
health-related quality of life and significant disability. Validated ... patients that were studied averaged 59 years in age. However, due to the poor
quality of life associated with the disease, the reported results were ...
Under the Microscope: 'Micro IVF'
... diminished pregnancy rate which for young high responders and older poor
responders will be minimal. The reason these groups would see a minimal ... embryos to produce the healthy one that will result in a baby. The older poor
responders do not make extra embryos with aggressive stimulation and have ...
Vion Pharmaceuticals Submits New Drug Application for Onrigin(TM)
... of these patients had two or more risk factors that predicted for a poor
prognosis. The Company presented data on this group of patients in a ... In addition, patients with risk factors such as advanced age and poor
performance status tolerate current induction treatments poorly. A 2005 ...
SuperGen Receives Clearance to Begin Clinical Trials With SGI-1776, a PIM Inhibitor
... frequency. Overexpression of Pim-1 kinase has
been shown to be a marker of poor
prognosis in these tumors. A second Phase
I/II study is being planned in ... leukemias in which Pim
kinases are also overexpressed, and correlated with poor
prognosis and drug
"We are pleased to acknowledge ...
Medivation Announces Presentation of 24-Week Clinical Data of MDV3100 in Castration-Resistant Prostate Cancer Patients
... option for patients with castration-resistant prostate cancer,
who have a poor
prognosis and for whom treatment options are limited."
MDV3100 Trial ... as hormone-refractory) prostate cancer have few treatment options and
Overexpression of the androgen receptor is believed to ...
Vaxfectin(R)-formulated Measles DNA Vaccine Could Address Unmet Need for Infants
... disease causes of deaths among
young children worldwide because of poor
vaccine acceptance in some
vaccine availability in others, and lack of effectiveness
in young ....
OncoGenex receives completed Special Protocol Assessment for primary registration study of lead drug candidate OGX-011
... expression is linked to disease
progression, treatment resistance, poor
prognosis and survival in
scientific publications. For example, increased ... with increasing Gleason score, which
is a strong prognostic factor for poor
survival of patients with prostate
About the Special Protocol ...
GlaxoSmithKline Responds to JAMA Article on the ICES Thiazolidinediones and Cardiovascular Outcomes in Older Patients with Diabetes
... the comparison group. This also permits more advanced patients, with poor
glycemic control and who are at greater risk of cardiovascular ... can cause or worsen heart failure. If you have severe heart
failure (very poor
pumping ability of the heart), you cannot be started on
Avandia. Avandia ...
Cellestis Receives FDA Approval for Blood Test for Detecting Tuberculosis
... bacteria, giving many people a
false- positive TST results. The TST has poor
reproducibility and requires
two patient encounters; one to inject the ... is still highly subjective, and is
notorious for inaccuracy. This leads to poor
use of valuable medical
resources, and the need for a second clinic visit ...
TSH Testing Raises Awareness of Importance of Thyroid Health
... almost 30 million Americans. If this common form of thyroid disease is not detected and treated, it may lead to cardiac disease, reproductive issues, poor
pregnancy outcomes, mental health concerns, obesity and a variety of autoimmune diseases, including diabetes," said Mangano.
Testing for ...
Rapid heating prepares energy-saving zeolite for greater role in industrial separations
... in large area; and the difficulty in controlling grain boundary defects, or non-selective pathways at the crystal grain interfaces, which cause poor
Meanwhile, an estimated 15 percent of the world's energy consumption is used for the industrial separations of molecules ...
Medicago's H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose
... culture technologies have advised the WHO that the influenza seed strain used to produce their new vaccine is not growing well and therefore giving poor
antigen yields. The yield is approximately 25-50% of that vaccine makers typically get for seasonal flu vaccine production. The WHO recently made a ...
Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors
... the gold standard but not without drawbacks such as pain, longer surgical times and more anesthesia. Certain patients including those at risk for poor
healing are not candidates for autologous grafts. A host of substitutes have been used with varying success. They include processed cadaver bone ...
iCardiac Processes Volume of Data Equivalent to One Thousand Traditional Thorough QT Studies
... of new drugs by measuring the QT segment of ECGs collected in clinical trials. The dissatisfaction among pharmaceutical developers with the poor
precision and high cost of the "gold standard" manual QT measurements has lead to efforts toward automating QT interval measurement.
SAPHRIS(R) (asenapine) Meets Primary Endpoint in Long-Term Extension Study in Patients With Predominant, Persistent Negative Symptoms of Schizophrenia
... with predominant, persistent negative symptoms of schizophrenia.
Negative symptoms of schizophrenia include apathy, lack of emotion and poor
social functioning, among others. In the study, these symptoms were assessed using the validated 16-item Negative Symptom Assessment scale (NSA-16). ...
Vi typhoid vaccine proves highly effective in young children
... and effective vaccines against typhoid fever exist, but they are used primarily for affluent travelers to developing countries, rather than for the poor
residing in these countries, who account for almost all the global burden of typhoid morbidity and mortality. One of these vaccines, Vi ...
Heart disease: Research off the beating patch
... people have seen with those clinical trials is that the cells end up in an environment that is not optimal for them to thrive in. Scar tissue offers poor
blood supply and weak structural support for new cells to attach, survive and grow. Our patch offers just what cardiac muscle cells need: structural ...
Studies Presented at International Conference on Alzheimer's Disease Reveal Substantial Economic Costs and Caregiver Burden Associated with Alzheimer's Disease
... alone can add significant burden to patients and their loved ones, but in combination with AD, they often translate into significant financial cost, poor
health outcomes, and higher risk of death. "I regularly see elderly patients who have multiple conditions that increase the complexity of their ...
Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer
... number of CTCs identified in patients with MBC is related to patient prognosis; a high number of CTCs at any time during treatment is associated with poor
"Veridex is committed to providing oncologists with high-value in vitro diagnostic solutions, such as the CellSearch(R) CTC test, ...
Harvest Technologies Announces Completion of Patient Enrollment in its 60 Patient Clinical Trial in India Using Autologous Adult Stem Cells to Treat Patients With Non-Reconstructable Critical Limb Ischemia
... status and quality of life, and is associated with an increased cardiovascular mortality and morbidity. Prognosis of critical limb ischemia is poor
and no effective treatments have been established in patients who are not amenable for the traditional revascularization therapies such as ...
Schering-Plough Announces Phase II and III Data for Corifollitropin Alfa
... of hCG as soon as three follicles 17 mm or greater were present. Vaginal progesterone was administered for luteal phase support. Patients with proven poor
response were excluded from participation. The main endpoint of this trial was ovarian response. The observed number of follicles, serum estradiol ...
Light sensor breakthrough could enhance digital cameras
... current from a device that takes advantage of MEG.
"Digital cameras are now universal, but they suffer from a major limitation: they take poor
pictures under dim light. One reason for this is that the image sensor chips inside cameras collect, at most, one electron's worth of current for ...
LNA-Based HIF-1 Alpha Inhibitor Shows Early Signs of Clinical Benefit
... HIF-1 alpha protein
is low in normal cells, but reaches high intracellular concentrations in a
variety of cancers and is strongly correlated with poor
resistance to therapy. Enzon is currently conducting two Phase I studies,
evaluating the HIF-1 alpha antagonist in different dosing ...
Micromet Presents Update at ASCO 2009 on a Phase 1b Combination Study of Adecatumumab and Docetaxel
... assessable for safety and n=19 evaluable for efficacy). Adecatumumab is an antibody that targets EpCAM, a tumor antigen known to be associated with poor
prognosis for breast cancer patients. Combining adecatumumab with docetaxel was feasible with clinically manageable diarrhea being the main toxicity ...
Plexus Awarded Development Contract With QIAGEN
... of the electronics, technology and defense industries; the risk of customer delays, changes or cancellations in both ongoing and new programs; the poor
visibility of future orders, particularly in view of current economic conditions; the effects of the volume of revenue from certain sectors or ...
500th Patient Receives Berlin Heart EXCOR Pediatric Ventricular Assist Device
... a heart-lung machine,
on 2 January 2009, but rapidly deteriorated. "She was difficult to support on
ECMO with a good deal of bleeding and relatively poor
recalls Dr. Jeffrey Gossett, Alejandra's cardiologist. "As a result we needed
to continue paralysis and were unable to feed her ...
Boston Scientific's SpyGlass(R) Direct Visualization System Featured in Broad Range of Clinical Studies at Upcoming Digestive Disease Week(R)
... CC but the absence of symptoms and the lack of reliable
diagnostic instruments for early detection of tumors contribute to
prognosis in patients. Direct visualization of the biliary
system is not yet a standard tool for excluding malignancy in bile
FDA Clears Boston Scientific's SpyScope(R) Access and Delivery Catheter for Use in Endoscopic Procedures Throughout Pancreatico-Biliary System
... with patients often not exhibiting symptoms until late in the disease process. As a result, the majority of patients with late-stage disease have a poor
prognosis for survival.
"Early detection is critical to improving outcomes in patients with pancreatic cancer, but the 'silent' nature of the ...
Doctors in New Hampshire Now Treating Cancer with Non-Invasive Image-Guided Radiosurgery Using Novalis Tx(TM) Technology
... capacity has been severely weakened," said Bickford, a retired assembler of printing presses. "Thoracic surgeons told me that because of the poor
condition of my lungs, I couldn't handle any kind of surgical procedure. Thankfully for me, there was another treatment option."
Prospect Therapeutics, Inc.'s GCS-100 Inhibited Blood Vessel Formation in a Variety of Cancer Models
... the activity of Galectin-3, a protein found in high concentration in a broad range of human cancers and whose over-expression is associated with poor
prognosis in cancer patients.
About Joseph F. Finn, Jr., C.P.A.
Joseph F. Finn, Jr., C.P.A. is the founding partner of the firm, Finn, ...
The Concerned Shareholders of Biovail Say Biovail Has Misled Shareholders
... the Concerned Shareholders have attempted to frustrate shareholder democracy at Biovail. This is further evidence of the Board's and management's poor
judgment and misguided view of governance. Their claim flies in the face of governance principles and is simply untrue.
- The Concerned ...
Prospect Therapeutics, Inc. Assigns All Its Assets to Joseph F. Finn, Jr., C.P.A. for the Benefit of Its Creditors
... the activity of galectin-3, a protein found in high concentration in a broad range of human cancers and whose over-expression is associated with poor
prognosis in cancer patients. It is presently in Phase 2 clinical trials. The intellectual property, regulatory dossier, fixed assets and clinical ...
Evoke Pharma, Inc. Initiates Phase 2b Metoclopramide Intranasal Trial (MINT) in Patients With Diabetic Gastroparesis
... vomiting of food ingested several hours previously, upper abdominal distention (bloating), early satiety, and anorexia. Severe symptoms may result in poor
nutrition and dehydration resulting in hospitalization.
About Evoke Pharma, Inc.
Evoke Pharma, Inc. is a privately ...
Independent Data Monitoring Committee Supports Continuation of Picoplatin Phase 3 SPEAR Registration Trial in Small Cell Lung Cancer
... SCLC patients were treated with therapy (American Cancer Society, Cancer Facts and Figures 2009). Patients with SCLC have few treatment options and a poor
prognosis. Effective second-line treatment for SCLC is a major unmet need.
Picoplatin is designed to overcome platinum ...
NeurogesX Presents Two Posters at 61st Annual American Academy of Neurology Annual Meeting
... among the medical community. Peripheral neuropathic pain syndromes can be difficult to treat and current treatment options are often limited by poor
tolerability, the need for titration, and administration of multiple daily doses.
About NeurogesX, Inc.
NeurogesX (NASDAQ: NGSX ) is ...
Medarex Announces Presentations at Annual Meeting of the American Society of Clinical Oncology
... time on Monday, June 1, 2009.
"Efficacy of ipilimumab 10 mg/kg in advanced melanoma patients (pts) with good and poor
prognostic factors" (Abstract #9036, Melanoma Session) J. Wolchok - General poster from 8:00 a.m. to 12:00 p.m. local time on Monday, June 1, 2009. ...