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Plaque in Biological Technology

SemBioSys' plant-derived Apo AI(Milano) demonstrates encouraging biologic activity in seven preclinical models

... activity, including the ability to reduce overall plaque volume. New data from two of the largest and ... studies on cholesterol mobilization and plaque lipid content were conducted, as well as, ... reduction of overall volume of atherosclerotic plaque after multiple injections. Full results of the ...

VIA Pharmaceuticals Announces Complete Enrollment in FDG-PET Phase 2 Study of VIA-2291 in Cardiovascular Patients

... study examines the impact of VIA-2291 on plaque inflammation as measured by Positron Emission ... reduction in necrotic core thickness relative to plaque thickness as measured with histology, and A significant reduction in plaque volume and a reduced number of ...

New Discoveries on a Fingertip Test for Screening Silent Heart Disease Promising Results of Recent Clinical Studies to be Presented during the 2009 American College of Cardiology Conference, March 29th - April 1st in Orlando

... The lower the temperature rebound, the more plaque buildup and blockage," said Dr. Mathew ... Texas Heart Institute while working on vulnerable plaque detection," said Dr. Morteza Naghavi, ... exciting developments in intracoronary plaque characterization, it became obvious to me that we ...

AstraZeneca Calls on All Americans to Join US AGAINST ATHERO to Fight the Nation's Number One Killer

... (athero), the progressive buildup of plaque inside the arteries. The Artery Explorer kicks ... see what happens when you allow the build-up of plaque to progress, and more importantly, what they can ... out of three Americans will have some degree of plaque build-up in their arteries.(1) However, athero ...

Photos: 'Project Runway's' Tim Gunn Launches Addressing Psoriasis(TM) Campaign to Advocate That Patients Shouldn't Let Psoriasis Impact Personal Style

... awareness campaign designed to help people with plaque psoriasis get more information about managing ... are working together to encourage people with plaque psoriasis to visit a dermatologist and take the ... to recognize people who have moderate to severe plaque psoriasis but who try not to allow the condition ...

New Biologic STELARA(TM) Receives Approval in Europe for Treatment of Moderate to Severe Plaque Psoriasis

... is for the treatment of moderate to severe plaque psoriasis in adults who failed to respond to, or ... offers adults living with moderate-to-severe plaque psoriasis a new therapy which has the potential ... in the treatment of moderate-to-severe plaque psoriasis were evaluated.(4,5) Two-thirds or more ...

vProtect(TM) Luminal Shield Stabilizes Life-Threatening Plaque

... to Receive Preventive Treatment for Vulnerable plaque ROTTERDAM, Netherlands and DOYLESTOWN, Pa., ... focal preventive treatment for vulnerable plaque recently underwent a 6-month follow-up ... succeeded in preventing heart attacks related to plaque rupture. The vProtect(TM) Luminal Shield has ...

Replidyne and Cardiovascular Systems Sign Merger Agreement

... in the U.S. PAD is caused by the accumulation of plaque in peripheral arteries (commonly the pelvis or ... range from soft to calcified, with calcified plaque being difficult to treat with traditional ... position the crown at the site of an arterial plaque lesion and remove ...

ev3 Inc. Reports Third Quarter 2008 Financial Results

... performance and value that the SilverHawk plaque Excision System offers as a front-line therapy in ... Ca++ U.S. IDE trial to evaluate RockHawk plaque Excision System when used in conjunction with the ... today -- peripheral angioplasty balloons, stents, plaque excision systems, embolic protection ...

Old and new therapies combine to tackle atherosclerosis

... Statins also decrease atherosclerotic plaque progression by modestly inhibiting proliferation ... (brand name Lipotor) had no change in plaque angiogenesis measured by MRI. When the statin and ... on statins could lead to a long-term reduction in plaque activity and ...

SemBioSys announces second quarter 2008 financial and operational results

... AI(Milano) with respect to plaque-remodeling and plaque regression. The upcoming milestone ... - Completion of in vivo efficacy studies of plaque remodeling with safflower-produced Apo AI(Milano) followed by studies of plaque regression using a mouse model. - ...

SemBioSys Demonstrates Functionality of its Safflower Produced Apo AI(Milano)

... Apo AI(Milano) has been demonstrated to remove plaque from arteries (plaque regression), and holds ... through the unique mechanism of plaque regression. Our research at the MHI fully ... to as "good cholesterol", which naturally removes plaque from arteries. Published studies have shown ...

Interleukin Genetics Enters into New Clinical Research Collaboration with Alticor

... artery disease (CAD) is a disease in which plaque builds up inside the coronary arteries. These ... supply your heart muscle with oxygen-rich blood. plaque is made up of fat, cholesterol, and other substances found in the blood. When plaque builds up in the arteries, the condition is ...

Synvista Therapeutics to Develop Topical Formulation of ALT-2074 for the Treatment of Psoriasis

... for a potential therapy in mild-to-moderate plaque psoriasis. TNF-alpha is an established target for ... may be a promising therapy for mild-to-moderate plaque psoriasis, without the side effects associated ... to perform a planned Phase 2 clinical trial for plaque psoriasis beginning mid-2008, pending ...

ev3 and FoxHollow Announce Date for Special Meeting of FoxHollow Stockholders to Vote on Proposed Merger

... minimally invasive devices for the removal of plaque and thrombus for the treatment of peripheral artery disease (PAD). PAD results from plaque that accumulates in the arteries and blocks blood ... physical mobility. The company's SilverHawk plaque Excision System is a minimally invasive method of ...

SemBioSys updates Apo AI development program

... to rapidly stabilize and diminish atherosclerotic plaque for the prevention and treatment of ... to as "good cholesterol", which naturally removes plaque from arteries. Apo AI Milano is a natural ... variant/phospholipid formulation could reduce plaque volume at a level and speed of atherosclerotic ...

First Use in Coronary Patients of a Combined Near-Infrared Spectroscopy and Ultrasound Imaging Catheter

... to assess the effect of novel anti-atherosclerotic agents on lipid core plaque burden. About InfraReDx, Inc. InfraReDx, Inc. is a ... system utilizing near-infrared spectroscopic (NIRS) technology to identify plaque composition. It has now developed IVUS technology to provide ...

Industry Expert Reveals Cutting Edge Biotechnology Science for Nutraceutical and Functional Food Applications

... Advana Science has found safe, natural scientific discoveries for amyloid plaque reduction that are linked to major degenerative diseases, including ... patents include memory enhancement, cognitive improvement and amyloid plaque reduction in humans. Contact: Diana Levine 917-864-0885 ...

Spherix Announces 2008 Financial Results

... a diet enriched in D-tagatose may favor a more stable, less vulnerable plaque phenotype, a plaque that is less like to rupture. Webcast Info Earnings Call: ...

BioCryst Reports Fourth Quarter and Year End 2008 Financial Results and Provides Corporate Update

... Inhibitor RO5092888 (BCX-4208) in Patients with Moderate to Severe Chronic plaque Psoriasis: Safety, Tolerability and Lymphocyte Effects" was presented at ... and tolerability of BCX-4208 in patients with moderate to severe chronic plaque psoriasis. Results showed BCX-4208 was safe and well tolerated. ...

Interleukin Genetics to Present New Findings at the 11th Cardiovascular Genomics and Atherosclerosis Symposium

... arteries. These arteries supply your heart muscle with oxygen-rich blood. plaque is made up of fat, cholesterol, and other substances found in the blood. When plaque builds up in the arteries, the condition is called atherosclerosis. ...

HealthYes! - Premier Provider of Mobile Preventive Medical Screenings - Launches in Alamo City

... help identify conditions affecting blood flow, blood flow velocities, and plaque build-up. Eighty-seven percent of all strokes occur due to clots that ... Artery Disease (PAD) Screening -- An oscillometry machine detects plaque build-up which occurs as the arteries in the legs narrow and harden ...

BioSpecifics Technologies Corp. Buys Down Royalties for Peyronie's Disease

... and make intercourse difficult or impossible in advanced cases. The plaque is not elastic and it does not stretch during erection. In some mild ... can resolve spontaneously without medical intervention. The most common plaque forms on the top of the penis causing the penis to arc upward. In severe ...

FDA Extends Review Timeline for Ustekinumab Biologic License Application Three Months

... for the treatment of adult patients with chronic moderate to severe plaque psoriasis. The FDA extended the review period to provide additional time ... 3 development by Centocor, Inc. for the treatment of moderate to severe plaque psoriasis, and is being investigated as an infrequently administered ...

SemBioSys announces first quarter 2008 financial and operational results

... Apo AI(Milano) - Completion of in vivo efficacy studies of plaque remodeling with safflower-produced Apo AI(Milano) followed by studies of plaque regression - Initiation of a formal partnering process for Apo AI ...

Device That Clears Debris From Artery Aids Blood Flow in PCI

... -- Use of a special catheter that sucks out, or aspirates, bits of plaque and blood clot that break loose during percutaneous coronary intervention ... that has been blocked by a blood clot. However, bits of atherosclerotic plaque and blood clot can break loose during angioplasty and stenting, traveling ...

Volcano Announces FDA 510(k) Clearance of Revolution Rotational Catheter and FFR for the s5i Integrated IVUS Console

... patients. If a physician wants a high resolution IVUS image to measure plaque burden, they can select a Revolution(TM) IVUS catheter. If they want a ... including ChromaFlo(R) for stent apposition assessment, and VH(TM) IVUS plaque composition analysis. The Volcano s5 Imaging System has been tested in ...

Topspin Medical Announces First Commercial Installation of the Cathamaran(TM) Intravascular MRI System

... IVMRI System will be used in a post-market Study of coronary plaque lipid characterization by IVMRI performed during diagnostic or ... our company. We are committed to advancing investigation into vulnerable plaque with the goal of improving diagnosis of these high-risk lesions and aiding ...

AstraZeneca and Banner Alzheimer's Institute Collaborate to Evaluate New Tool Targeting Alzheimer's Disease

... by AstraZeneca. This radioligand is a molecule that binds to amyloid plaque -- protein deposits in the brain that are a hallmark of Alzheimer's disease -- and allows the plaque to be measured in real time using a positron emission tomography (PET) ...

Abbott's HUMIRA(R) Receives Positive Opinion From EMEA for Treatment of Moderate to Severe Plaque Psoriasis

... approval of HUMIRA(R) (adalimumab) for the treatment of moderate to severe plaque psoriasis. Psoriasis will be the fifth disease indication for HUMIRA. ... from the United States and Canada with moderate to severe chronic plaque psoriasis. Patients experienced a significant reduction in the signs ...

Clinical Study Findings Show Safety and Procedure Success for TopSpin IntraVascular MRI Catheter for the Coronary Arteries

... IVMRI measurement was obtained in 95% of patients. Rupture of coronary plaque with subsequent thrombus (blood clot) formation is the underlying cause of ... imaging and characterization of the tissue lipid composition of coronary plaque during a conventional cardiac catheterization procedure. The IVMRI ...

Schering-Plough Reports Financial Results for 2009 Second Quarter

... (except in Japan and certain other Asian markets) for rheumatoid arthritis, early rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn's disease, pediatric Crohn's disease and ulcerative colitis. Global sales of NASONEX, an inhaled nasal corticosteroid for ...

VIA Pharmaceuticals' DGAT1 Inhibitors Featured in American Diabetes Association Poster Presentation

... cardiovascular clinical trials using histological examinations, measurement of biomarkers, medical imaging and atherosclerotic plaque bioassays; -- the results of our clinical trials, including without limitation, with respect to the safety and efficacy of ...

Multiple Types of Heart Attacks Reduced by Prasugrel in TRITON-TIMI 38 Trial

... this study, according to the definition, included: Type 1: Spontaneous heart attack caused by a primary coronary event, such as a plaque rupture in a coronary artery with less blood then flowing to the muscle Type 2: Secondary heart attack due to either increased oxygen demand ...

VIA Pharmaceuticals Receives Anticipated Notice From NASDAQ

... cardiovascular clinical trials using histological examinations, measurement of biomarkers, medical imaging and atherosclerotic plaque bioassays; -- the results of our clinical trials, including without limitation, with respect to the safety and efficacy of ...

VIA Pharmaceuticals to Present Poster at AHA Arteriosclerosis, Thrombosis and Vascular Biology Conference 2009

... cardiovascular clinical trials using histological examinations, measurement of biomarkers, medical imaging and atherosclerotic plaque bioassays; -- the results of our clinical trials, including without limitation, with respect to the safety and efficacy of VIA-2291; ...

VIA Pharmaceuticals Complies With NASDAQ Rules

... and implementing cardiovascular clinical trials using histological examinations, measurement of biomarkers, medical imaging and atherosclerotic plaque bioassays; the results of our clinical trials, including without limitation, with respect to the safety and efficacy of VIA-2291; if ...

VIA Pharmaceuticals Secures Financing Up to $10.0 Million

... and implementing cardiovascular clinical trials using histological examinations, measurement of biomarkers, medical imaging and atherosclerotic plaque bioassays; the results of our clinical trials, including without limitation, with respect to the safety and efficacy of VIA-2291; if ...

BioCis Pharma Starts Phase IIa Trial in Psoriasis

... study is designed to evaluate the tolerability, pharmacokinetics, and efficacy of the topical product in a total of 18 subjects with mild to moderate plaque psoriasis. The subjects will apply ProtoCure(TM) emulsion cream up to four weeks to the skin areas affected by the disease. "With the ...

Buckyballs could keep water systems flowing

... with these nanoparticles may prove to be an effective strategy for addressing one of the major problems and costs of treating water. "Just as plaque can build up inside arteries and reduce the flow of blood, bacteria and other microorganisms can over time attach and accumulate on water treatment ...
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