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Phosphorus in Biological Technology

Keryx Biopharmaceuticals Reports Positive Phase 2 Study Results of Zerenex (Ferric Citrate) for the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients

... weekly to achieve and maintain normal serum phosphorus levels, between 3.5 to 5.5 mg/dL, the therapeutic ... Baseline mean + standard deviation (SD) serum phosphorus was approximately 5.9 + 1.5 mg/dL immediately ... four weeks on Zerenex) the mean + SD serum phosphorus was approximately 5.4 + 1.3 mg/dL; The ...

ChartTrends(R): Bone and Mineral Metabolism in Dialysis Reveals Latest Trends in the Treatment of Calcium, Phosphorus and PTH

... insight into the management of calcium, phosphorus and PTH in dialysis patients. The report is ... be initiated on phosphate binder monotherapy when phosphorus reaches 5.7 mg/dL. phosphorus levels are significantly higher when combination ...

Bion Announces Approval of New U.S. Patent for Phosphorus Removal Process for Livestock Waste Environmental Treatment

... in force until December 26, 2021. Bion's new phosphorus removal patent coverage broadens and deepens ... process's unique ability to convert and remove phosphorus from the waste stream. Excess nutrients from livestock waste, primarily phosphorus and nitrogen, have been shown to cause serious ...

Genzyme Launches Renvela(R) in the U.S. for Dialysis Patients

... approval of Renvela for the control of serum phosphorus in chronic kidney disease patients regardless of ... Renvela (sevelamer carbonate) both control serum phosphorus in patients with chronic kidney disease (CKD) on dialysis. Controlling serum phosphorus is an important element in the care of dialysis ...

Katie Lee Joel to Conduct Free, Hands-On, Holiday Cooking Demonstration for Local Patients With Chronic Kidney Disease

... will develop hyperphosphatemia (high serum phosphorus levels in the blood). Excess phosphorus in the blood can be associated with serious ... vessels, bone disease and even death. Because phosphorus is found in so many foods, patients often cannot ...

FDA Approves Genzyme's Renvela(TM) for Dialysis Patients

... (sevelamer carbonate) for the control of serum phosphorus in patients with chronic kidney disease ... Renvela to Renagel, both drugs controlled serum phosphorus equally to within KDOQI recommended ranges. ... extension for Renagel for the control of serum phosphorus for patients on peritoneal dialysis. ...

Genzyme to Participate in FDA Advisory Committee Meeting on the Use of Phosphate Binders in Chronic Kidney Disease

... of Renvela tablets for the control of serum phosphorus in patients with CKD who are not on dialysis. A ... help patients achieve the target levels for phosphorus and calcium-phosphorus product outlined in the ... (K/DOQI) guidelines. Renagel controls serum phosphorus in patients with chronic kidney disease on ...

Amgen's Fourth Quarter 2008 Adjusted Earnings Per Share Increased 6 Percent to $1.06; Full Year 2008 Adjusted Earnings Per Share Increased 6 Percent to $4.55

... well tolerated and showed a statistically significant reduction in serum phosphorus compared with placebo. While these results were consistent with what is ... product. AMG 223 is a non-absorbed, metal-free polymer that binds phosphorus in the gastrointestinal tract. For more product information or the ...

Cytochroma initiates Phase I/II clinical trial of CTAP101 Capsules for vitamin D insufficiency in chronic kidney disease

... The safety endpoints for the trial include serum and urine calcium, serum phosphorus and the serum calcium times serum phosphorus product. "We are pleased to be advancing this first-in-class prohormone ...

Bion Announces Approval of New U.S. Patent that Broadens Protection for the Company's Livestock Waste Environmental Treatment Processes

... systems to Bion's clients. James Morris, Ph.D., P. E., Bion's Chief Technology Officer, stated, "This new patent describes the removal of phosphorus utilizing a new and unique process and system configuration. Bion now has in hand a very broad array of patents protecting variations and ...

New Greenline Tea FASTRACK Solves Cold-Flow Issues

... ASTM cold-soak test. B100 (100 percent biodiesel) passed through the Greenline Tea process will remove sterol glucosides, monoglycerides, sulfur and phosphorus with minimal impact on product yield. "We want to remove any technical barriers to biodiesel adoption; our vision is to make biodiesel ...

Bion Announces PENNVEST Board Approves $7.8 Million Financing for Kreider Farms Dairy Project

... system will not only reduce nutrient impacts on the Chesapeake Bay, it will also significantly reduce local environmental impacts such as odor, phosphorus releases to the local creeks, a host of air emissions such as hydrogen sulfide and methane (greenhouse gas emissions), as well as pathogens. ...

BioTrends Releases TreatmentTrends(TM): US Nephrology, an Ongoing Syndicated Publication Providing Insight into Physician Perceptions and Management of Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism

... the largest group of Nephrologists report patient non-compliance due to the frequency with which current binders have to be taken as the main reason phosphorus is difficult to control in dialysis patients. A more near-term shift in market dynamics will likely come from the recent introduction of generic ...

Genzyme Reports Strong Second-Quarter Growth

... labeling for Renvela(R) (sevelamer carbonate) will be expanded by mid-2009 to include the treatment of chronic kidney disease patients with elevated phosphorus levels who are not on dialysis. Genzyme, along with two other companies, submitted a position paper to the FDA in May regarding this expanded use of ...

Research helps understand factors that influence efficiency of organic-based devices

... binding of a self-assembled monolayer of phosphonic acid to the indium tin oxide surface. Paramonov's first goal was to determine how the oxygen and phosphorus atoms of the self-assembled monolayer bind to the indium tin oxide surface. In collaboration with Seth Marder, a professor in the Georgia Tech ...

Bion Outlines Differences between its Patented Comprehensive Livestock Environmental Treatment Technology and Anaerobic Digesters

... be used or converted to electricity on-site. The AD process is focused on energy production. It provides essentially no reductions in nitrogen and phosphorus in the effluent and actually increases nutrient solubility, even when compared to land application of untreated manure. The presence of nutrients in ...

BioTrends Releases Fourth Annual Nephrology TreatmentTrends Publication Highlighting Market Trends for Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism

... "not at all familiar" with the product. In the phosphate binder market, nephrologists seem to be in agreement about the importance of controlling phosphorus in pre-dialysis patients, with 62% reporting "phosphorus" as the most important level to keep within target range (over PTH and calcium). This has ...

ASU researchers improve memory devices using nanotech

... materials already common in chip manufacturing. Although doping mixing silicon with small amounts of conductive materials such as boron, arsenic or phosphorus has been common practice for years, copper in silicon dioxide was largely unheard of. In fact, it was strictly avoided. People have actually gone ...

Keryx Biopharmaceuticals, Inc. Enters into Licensing Agreement with Japan Tobacco and Torii Pharmaceutical for Development and Commercialization of Hyperphosphatemia Drug in Japan

... and the progression of renal failure. ESRD patients usually require treatment with phosphate-binding agents to lower and maintain serum phosphorus at acceptable levels. There are over 300,000 dialysis patients in the United States, and even with current therapy, hyperphosphatemia persists in 70% ...

Madison life-science firms agree to co-develop kidney product

... with chronic kidney disease is to maintain serum phosphorus levels within normal limits. Under the terms ... that after nearly four decades of experience with phosphorus management strategies in kidney patients, phosphorus control remains elusive. The aim of this ...

Microdetermination of Phosphorus Using the SpectraMax Plus Microplate Spectrophotometer: Choice of Microplate, Cuvette, or Test Tube Assay Formats (MaxLine Application Note #24)

... Most spectrophotometric methods for inorganic phosphorus (Pi) analysis are based on the color formed upon ... note details two methods for measuring inorganic phosphorus using Molecular Devices SPECTRAmax PLUS ... 4. Pipettor and tips 5. Inorganic phosphorus kit (Sigma Chemical Co., catalog # 670-C) ...

FDA approves Bone Cares Hectorol for treatment of kidney disease

... hormone levels decline with SHPT typically characterized by a subsequent decrease in calcium levels along with elevated parathyroid hormone (PTH) and phosphorus levels. If left untreated, SHPT can eventually result in cardiovascular disease, reduced immune system function, muscle weakness and bone mineral ...

Analysis of urine and seawater samples by ultrasonic nebulization with a high resolution ICP spectrometer

... 1. ICP At Work No. 8, Nham T. T., Varian, Mulgrave, Victoria, 1992. 2. Determination of silicon, calcium, magnesium and phosphorus in urine using inductively coupled plasma emission spectrometry and a matrix matching technique, Tanaka T., Hayashi Y., Clin. Chim. Acta, 1986, 156 ...

Preparative Nondenaturing Gel Electrophoresis to Purify NADP-Specific Glutamate Dehydrogenase From Chlorella, Rev B

... Ingram for the use of the Model 491 prep cell. References Baker AL and Schmidt RR, Intracellular distribution of phosphorus during synchronous growth of Chlorella pyrenoidosa, Biochem Biophys Acta 74, 7583 (1963) Bascomb NF and Schmidt RR, ...
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