Keryx Biopharmaceuticals Reports Positive Phase 2 Study Results of Zerenex (Ferric Citrate) for the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients
... weekly to achieve and maintain normal serum phosphorus
levels, between 3.5 to 5.5 mg/dL, the therapeutic ... Baseline mean + standard deviation (SD) serum phosphorus
was approximately 5.9 + 1.5 mg/dL immediately ... four weeks on Zerenex) the mean + SD serum phosphorus
was approximately 5.4 + 1.3 mg/dL;
ChartTrends(R): Bone and Mineral Metabolism in Dialysis Reveals Latest Trends in the Treatment of Calcium, Phosphorus and PTH
... insight into the management of calcium, phosphorus
and PTH in dialysis patients. The report is ... be initiated on phosphate binder monotherapy when phosphorus
reaches 5.7 mg/dL. phosphorus
levels are significantly higher when combination ...
Bion Announces Approval of New U.S. Patent for Phosphorus Removal Process for Livestock Waste Environmental Treatment
... in force until December
Bion's new phosphorus
removal patent coverage broadens and deepens ... process's unique ability to
convert and remove phosphorus
from the waste stream. Excess nutrients from
livestock waste, primarily phosphorus
and nitrogen, have been shown to
cause serious ...
Genzyme Launches Renvela(R) in the U.S. for Dialysis Patients
... approval of Renvela for the control of
in chronic kidney disease patients regardless of ... Renvela (sevelamer carbonate)
both control serum phosphorus
in patients with chronic kidney disease (CKD)
on dialysis. Controlling serum phosphorus
is an important element in the
care of dialysis ...
Katie Lee Joel to Conduct Free, Hands-On, Holiday Cooking Demonstration for Local Patients With Chronic Kidney Disease
... will develop hyperphosphatemia (high
levels in the blood). Excess phosphorus
in the blood can
be associated with serious ... vessels, bone disease and even death. Because phosphorus
found in so many foods, patients often cannot ...
FDA Approves Genzyme's Renvela(TM) for Dialysis Patients
... (sevelamer carbonate) for
the control of serum phosphorus
in patients with chronic kidney disease ... Renvela to Renagel, both
drugs controlled serum phosphorus
equally to within KDOQI recommended
ranges. ... extension for Renagel for the
control of serum phosphorus
for patients on peritoneal dialysis. ...
Genzyme to Participate in FDA Advisory Committee Meeting on the Use of Phosphate Binders in Chronic Kidney Disease
... of Renvela tablets for the
control of serum phosphorus
in patients with CKD who are not on dialysis. A ... help patients
achieve the target levels for phosphorus
and calcium-phosphorus product
outlined in the ... (K/DOQI) guidelines. Renagel controls serum phosphorus
in patients with chronic kidney
disease on ...
Amgen's Fourth Quarter 2008 Adjusted Earnings Per Share Increased 6 Percent to $1.06; Full Year 2008 Adjusted Earnings Per Share Increased 6 Percent to $4.55
... well tolerated and showed a statistically significant reduction in serum phosphorus
compared with placebo. While these results were consistent with what is ... product. AMG 223 is a non-absorbed, metal-free polymer that binds phosphorus
in the gastrointestinal tract.
For more product information or the ...
Cytochroma initiates Phase I/II clinical trial of CTAP101 Capsules for vitamin D insufficiency in chronic kidney disease
... The safety endpoints for the
trial include serum and urine calcium, serum phosphorus
and the serum
calcium times serum phosphorus
product. "We are pleased to be advancing this first-in-class prohormone ...
Bion Announces Approval of New U.S. Patent that Broadens Protection for the Company's Livestock Waste Environmental Treatment Processes
... systems to Bion's clients.
James Morris, Ph.D., P. E., Bion's Chief Technology Officer, stated, "This new patent describes the removal of phosphorus
utilizing a new and unique process and system configuration. Bion now has in hand a very broad array of patents protecting variations and ...
New Greenline Tea FASTRACK Solves Cold-Flow Issues
... ASTM cold-soak test. B100 (100 percent biodiesel) passed through the Greenline Tea process will remove sterol glucosides, monoglycerides, sulfur and phosphorus
with minimal impact on product yield.
"We want to remove any technical barriers to biodiesel adoption; our vision is to make biodiesel ...
Bion Announces PENNVEST Board Approves $7.8 Million Financing for Kreider Farms Dairy Project
... system will not only reduce nutrient impacts on the Chesapeake Bay, it will also significantly reduce local environmental impacts such as odor, phosphorus
releases to the local creeks, a host of air emissions such as hydrogen sulfide and methane (greenhouse gas emissions), as well as pathogens.
BioTrends Releases TreatmentTrends(TM): US Nephrology, an Ongoing Syndicated Publication Providing Insight into Physician Perceptions and Management of Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism
... the largest group of Nephrologists report patient non-compliance due to the frequency with which current binders have to be taken as the main reason phosphorus
is difficult to control in dialysis patients. A more near-term shift in market dynamics will likely come from the recent introduction of generic ...
Genzyme Reports Strong Second-Quarter Growth
... labeling for Renvela(R) (sevelamer
carbonate) will be expanded by mid-2009 to include the treatment of chronic
kidney disease patients with elevated phosphorus
levels who are not on
dialysis. Genzyme, along with two other companies, submitted a position
paper to the FDA in May regarding this expanded use of ...
Research helps understand factors that influence efficiency of organic-based devices
... binding of a self-assembled monolayer of phosphonic acid to the indium tin oxide surface. Paramonov's first goal was to determine how the oxygen and phosphorus
atoms of the self-assembled monolayer bind to the indium tin oxide surface.
In collaboration with Seth Marder, a professor in the Georgia Tech ...
Bion Outlines Differences between its Patented Comprehensive Livestock Environmental Treatment Technology and Anaerobic Digesters
... be used or
converted to electricity on-site.
The AD process is focused on energy production. It provides essentially
no reductions in nitrogen and phosphorus
in the effluent and actually
increases nutrient solubility, even when compared to land application of
untreated manure. The presence of nutrients in ...
BioTrends Releases Fourth Annual Nephrology TreatmentTrends Publication Highlighting Market Trends for Renal Anemia, Hyperphosphatemia, and Secondary Hyperparathyroidism
... "not at all familiar" with the product.
In the phosphate binder market, nephrologists seem to be in agreement
about the importance of controlling phosphorus
in pre-dialysis patients,
with 62% reporting "phosphorus" as the most important level to keep within
target range (over PTH and calcium). This has ...
ASU researchers improve memory devices using nanotech
... materials already common in chip manufacturing. Although doping mixing silicon with small amounts of conductive materials such as boron, arsenic or phosphorus
has been common practice for years, copper in silicon dioxide was largely unheard of. In fact, it was strictly avoided.
People have actually gone ...
Keryx Biopharmaceuticals, Inc. Enters into Licensing Agreement with Japan Tobacco and Torii Pharmaceutical for Development and Commercialization of Hyperphosphatemia Drug in Japan
the progression of renal failure. ESRD patients usually require treatment
with phosphate-binding agents to lower and maintain serum phosphorus
acceptable levels. There are over 300,000 dialysis patients in the United
States, and even with current therapy, hyperphosphatemia persists in 70% ...
Madison life-science firms agree to co-develop kidney product
... with chronic kidney disease is to maintain serum phosphorus
levels within normal limits.
Under the terms ... that after nearly four decades of experience with phosphorus
management strategies in kidney patients, phosphorus
control remains elusive. The aim of this ...
Microdetermination of Phosphorus Using the SpectraMax Plus Microplate Spectrophotometer: Choice of Microplate, Cuvette, or Test Tube Assay Formats (MaxLine Application Note #24)
... Most spectrophotometric methods for inorganic phosphorus
(Pi) analysis are based on the color formed upon ... note details two methods for measuring inorganic phosphorus
using Molecular Devices SPECTRAmax PLUS ...
4. Pipettor and tips
5. Inorganic phosphorus
kit (Sigma Chemical Co., catalog # 670-C)
FDA approves Bone Cares Hectorol for treatment of kidney disease
... hormone levels decline with SHPT typically characterized by a subsequent decrease in calcium levels along with elevated parathyroid hormone (PTH) and phosphorus
levels. If left untreated, SHPT can eventually result in
cardiovascular disease, reduced immune system function, muscle weakness and bone mineral ...
Analysis of urine and seawater samples by ultrasonic nebulization with a high resolution ICP spectrometer
1. ICP At Work No. 8, Nham T. T., Varian, Mulgrave, Victoria, 1992.
2. Determination of silicon, calcium, magnesium and phosphorus
in urine using inductively coupled plasma emission spectrometry and a matrix matching technique, Tanaka T., Hayashi Y., Clin. Chim. Acta, 1986, 156 ...
Preparative Nondenaturing Gel Electrophoresis to Purify NADP-Specific Glutamate Dehydrogenase From Chlorella, Rev B
... Ingram for the use of the Model 491 prep cell.
Baker AL and Schmidt RR, Intracellular distribution of phosphorus
synchronous growth of Chlorella pyrenoidosa, Biochem Biophys Acta 74,
Bascomb NF and Schmidt RR, ...