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Pancreas in Biological Technology

Oncolytics Biotech Inc. Collaborators Present Positive Combination REOLYSIN(R) and Docetaxel Results at iSBTc Annual Meeting

... ------------------------------------------------------------------------- pancreas 3x10(10) 6* SD ... ------------------------------------------------------------------------- pancreas 3x10(10) 2 SD, but progressed ...

CyberKnife System Achieves 38 Percent Growth in Extracranial Treatments During Fiscal Year 2008

... treatment grew approximately 95 percent worldwide, while lung, liver and pancreas treatments experienced double-digit growth. The ability of the ... for tumors throughout the body, including the brain, spine, lung, liver, pancreas and prostate. Additionally, many studies are currently underway to further ...

Amylin Pharmaceuticals to Present Promising Data From Diabetes and Obesity Programs at ADA 2008

... who use insulin, and in patients with type 1 diabetes, those cells in the pancreas are either damaged or destroyed, resulting in reduced secretion of both ... through multiple effects that work in concert on the stomach, liver, pancreas and brain. BYETTA is approved by the FDA for use by people with type 2 ...

Novocell Reports Successful Use of Stem Cells to Generate Insulin in Mice

... that successfully engineers hES cells into specific cells necessary for pancreas formation, and endocrine cells capable of producing insulin and other ... About Diabetes Type 1, or insulin-dependent diabetes occurs when the pancreas ceases to produce insulin due to an autoimmune response that causes the ...

Breakthrough research identifies how cells from pigs may cure diabetes

... Society the Cell Transplant Society (CTS), the International pancreas and Islet Transplant Association (IPITA) and the International ... has shown that the transplantation of islet cells, harvested from the pancreas of a pig, yields a long-term reversal of diabetes in monkeys, opening the ...

Repligen Reports First Quarter Fiscal Year 2010 Financial Results

... innovative products that have the potential to markedly improve patients' lives." Corporate Update RG1068 for Imaging of the pancreas We are currently enrolling patients in a Phase 3 clinical trial of RG1068, synthetic human secretin, designed to assess the ability of RG1068 in ...

Amylin Pharmaceuticals Announces Positive Results from Dose-Ranging Clinical Study of Pramlintide/Metreleptin Combination Treatment for Obesity

... Combination Treatment Pramlintide acetate is a synthetic analog of the natural hormone amylin, a neurohormone secreted by the pancreas that is known to play a role in the regulation of appetite, food intake and postprandial glucose concentrations. To date, approximately 8,000 ...

New Drug Application for Exenatide Once Weekly Accepted for Review by FDA

... glucagon like peptide-1 (GLP-1). GLP-1 improves blood sugar after food intake through multiple effects that work in concert on the stomach, liver, pancreas and brain. BYETTA is approved by the FDA for use by people with type 2 diabetes who are unsuccessful at controlling their blood sugar levels. BYETTA ...

Repligen Reports Fourth Quarter and Fiscal Year 2009 Financial Results

... net loss of $3,198,000 or $0.10 per diluted share in the same period in fiscal year 2008. Corporate Update RG1068 for Imaging of the pancreas We are currently enrolling patients in a Phase 3 clinical trial of RG1068, synthetic human secretin, designed to assess the ability of RG1068 in ...

FDA Clears Boston Scientific's SpyScope(R) Access and Delivery Catheter for Use in Endoscopic Procedures Throughout Pancreatico-Biliary System

... cancer or pre-cancerous tissues. According to the American Cancer Society, in 2008 nearly 38,000 Americans were diagnosed with cancer of the pancreas -- the fourth-leading cause of cancer death in the U.S. Pancreatic cancer is a "silent" disease, with patients often not exhibiting symptoms until ...

Exenatide Once Weekly New Drug Application Submitted to FDA for Type 2 Diabetes

... glucagon like peptide-1 (GLP-1). GLP-1 improves blood sugar after food intake through multiple effects that work in concert on the stomach, liver, pancreas and brain. BYETTA is approved by the FDA for use by people with type 2 diabetes who are unsuccessful at controlling their blood sugar levels. BYETTA ...

AEterna Zentaris Presents Phase 1 Results for AEZS-112 in Patients with Advanced Cancer and Lymphoma at AACR Annual Meeting in Denver

... with the following primary cancer types: trachea (39+), tongue (30+), thyroid (29+), prostate and melanoma (28), non-small cell lung cancer (26+), pancreas and 2x colorectal (20). Except for one patient with a background of gastrointestinal problems (GI) who had dose-limiting GI reactions and ...

Oncolytics Biotech(R) Inc. Announces Positive Results of U.K. Phase II REOLYSIN(R) and Radiation Combination Clinical Trial

... in patients with advanced cancers. A total of 16 heavily pretreated patients with advanced cancer (melanoma (5), colorectal (4), gastric (1), pancreas (1), ovarian (1), lung (1), cholangiocarcinoma (1), sinus (1), and thyroid (1)) were enrolled in the trial. Most patients had received prior ...

Groundbreaking Research Begins for Pancreatic and Lung Cancers

... cellular mechanisms. Using microarray technology, gene expression patterns in pancreatic tumor tissue are compared with those present in the normal pancreas tissue. Microarray technology allows examination of more than 20,000 genes in a single experiment. Differences in the expression of genes encoding ...

Exenatide Clinical Data Analysis Shows No Increased Risk of Cardiovascular Events

... glucagon like peptide-1 (GLP-1). GLP-1 improves blood sugar after food intake through multiple effects that work in concert on the stomach, liver, pancreas and brain. BYETTA is approved by the FDA for use by people with type 2 diabetes who are unsuccessful at controlling their blood sugar levels. BYETTA ...

Repligen Reports Third Quarter Fiscal Year 2009 Financial Results

... net income of $40,304,000 or $1.29 per diluted share in the same period in fiscal year 2008. Corporate Update RG1068 for Imaging of the pancreas We are currently enrolling patients in a Phase 3 clinical trial of RG1068, synthetic human secretin, designed to assess the ability of RG1068 ...

Study Shows Machine Perfusion Significantly Improves Transplant Results

... 270 LifePorts have perfused more than 12,000 kidneys in transplant programs worldwide. Medical devices for ex vivo preservation of the heart, lung, pancreas and liver are in pre-clinical development. ...

FDA Continues Review of Takeda's New Drug Application for Alogliptin (SYR-322), a DPP-4 Agent for Type 2 Diabetes

... action for lowering blood sugar levels. GLP-1 and GIP are excreted in the digestive tract following food intake, and stimulate the beta-cells in the pancreas --- thereby stimulating increased insulin secretion --- and it has also been confirmed that they improve the functioning of the beta cells ....

CISBIO Bioassays Launches Chromoa(TM) Chromogranin A ELISA Kit

... protein levels in serum when a neuroendocrine tumor is present in the human body. The most common neuroendocrine tumors affect the adrenal gland, the pancreas and the digestive track. Chromogranin A (CgA) is an increasingly essential analyte for the detection and monitoring of these tumors as well as ...

British School Kids With Diabetes Gain First Time Freedom From Injections With New Insulin Pump Guidelines

... where they can experience the Accu-Chek Spirit online simulator, the most advanced insulin pump from Roche which closely mimics the pancreas by delivering insulin every three minutes(vii). About Roche Headquartered in Basel, Switzerland, Roche is one of the world's leading ...

Amylin Pharmaceuticals and Eli Lilly Provide Context for FDA Alert for BYETTA

... glucagon-like peptide-1 (GLP-1). GLP-1 improves blood sugar after food intake through multiple effects that work in concert on the stomach, liver, pancreas and brain. BYETTA is approved by the FDA for use by people with type 2 diabetes who are unsuccessful at controlling their blood sugar levels. BYETTA ...

BioTime, Inc. and Embryome Sciences, Inc. Sign Agreement With International Stem Cell Corporation to Provide Unique Human Stem Cell Lines for Research Use

... cell lines) possess the potential to expand and become specific types of tissues and cells such as heart, skeletal muscle, bone, retinal, nerve, pancreas and others – all necessary to study various human diseases where regenerative medicine shows great promise. "There is a large ...

Insulet Reports First Quarter 2008 Results

... of cancer. * Insulet is an industry partner in a majority of the sites supporting the Juvenile Diabetes Research Foundation's Artificial pancreas Project. As a result of the OmniPod System's role in the project, John Garibotto, Insulet's Vice President of Research, Development & ...

Epeius Biotechnologies Awarded U.S. Patent for Targeted Injectable Gene Delivery In Vivo

... Rexin-G is being tested as a single therapeutic agent in three separate U.S. Phase I/II Trials for recurrent or metastatic cancers of the breast or pancreas and for bone and soft tissue sarcoma respectively. Additionally, a Phase II Registration Protocol is underway for chemo-resistant osteosarcoma in Los ...

MannKind Announces Positive Results from a Phase 1a Study of a GLP-1 Formulation

... insulin release occurred within 6 minutes of inhalation of MKC253. The insulin response was dose-dependent. The release of insulin from the pancreas was confirmed by corresponding significant increases in the levels of C-peptide. In subjects that received 1.5 mg of MKC253, blood glucose ...

Smart insulin nanostructures pass feasibility test, UT study reports

... release system that detects spikes in glucose or blood sugar levels and releases insulin to counteract them. Designed to mimic functions of the pancreas which produces the blood-sugar regulating hormone insulin, the smart particle system stabilized blood sugar levels in animal models with suppressed ...

Barriers will not stop convergence of medical technologies

... this simple paradigm. Blood flowing to the pancreas does, indeed, come from the heart but the blood (now supplemented with insulin) leaving the pancreas actually enters a special vein called the portal ... functioning beta cells are transplanted into the pancreas (and presumably in proper anatomic position as ...

Detection of K-ras Point Mutations in the Pancreas by Constant Denaturing Gel Electrophoresis Using the DCode System

... Archived, formalin-fixed, paraffin-embedded pancreas tissue samples of patients without ... 95% of ductal adenocarcinoma of the pancreas (data not shown). ... 3. Chu, T. M., Molecular diagnosis of pancreas carcinoma, J. Clin. Lab. Anal. 11 , ...

TURBO DNase: Hyperactive, Salt Tolerant DNase

... is 10 7 -fold lower in RNase activity than bovine pancreas A New Hyperactive DNase with Superior ... as much as 1 mg of RNase A can be present in 1 g of pancreas tissue. Thus, many commercially available ...

Lifting federal limits on stem cell research would speed search for cures

... take years to produce a marketable product. If society wants to speed the day when stem cells can replace diseased cells or repair the human brain, pancreas or heart, the limits on federal funding should be lifted. ...

The passing of Ronald Reagan, and other Americans, is a reminder of the promise of stem-cell research

... brain cells, thus reversing or at least stabilizing Alzheimers and Parkinsons. They might replace damaged cells in spinal cords, or regenerate a pancreas shattered by diabetes. It is possible to create new stem cell lines without crossing the line into what opponents describe as trafficking in body ...

The more ways to produce stem cells, the better. Thats how science works

... of the donor, most scientists believe the excess DNA must be removed before the hybrid, or fusion, cells could be coaxed into growing into a liver, a pancreas or some other body part. If this stuff proves to work, thats wonderful, said John Gearhart, a stem cell researcher at Johns Hopkins Medical ...

RNAlater Around the World: The Art of Processing Difficult Samples

... exciting discoveries around the world. Pancreas--Germany Isolating intact RNA from pancreas can be difficult because of high levels of nucleases expressed in this tissue. In a study about circadian ...

RNase Activity in Mouse Tissue: Classification, Hierarchy, and Methods for Control

... of total RNase activities for 8 different mouse tissues showed that total RNase activity spans a 181,000-fold range from pancreas to brain (Figure 1), which highlights the level of RNase control required for successful RNA isolation. Figure 1. ...

Measuring RNase Activity A Real-time Kinetic Analysis

... the environment, and they are present in relatively high concentrations in many biological materials. For example, the pancreas is rich in RNase (>1 mg RNase/1 g tissue) and is the source for most commercially produced RNase A (and its ...

Isolate It All: siRNA miRNA Total RNA Native Protein

... Thus, the procedure is not compatible with tissues that contain very high levels of these enzymes, such as pancreas or spleen. To test for potential loss of RNA integrity during sample homogenization, total RNA was isolated ...

Identification of Low-Level Oxidation Products in Calmodulin Using NanoSpray Ion Trap Mass Spectrometry

... dried under vacuum, re-dissolved in 50-mM Tris-HCl buffer (pH 8.2), and digested with sequencing-grade bovine pancreas trypsin for 12 hours at 37 C with a CaM:trypsin ratio of 100:1. Sample Analysis: The CaM digest was ...

Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance

... lung, muscle, spleen, heart, and liver RNA. Other experiments confirmed their expression in the ovary, testis, cerebellum, and pancreas (data not shown). Figure 2 shows PCR results obtained with primer pairs for the low-abundance genes ARF1 ...
Other Contents
(Date:7/25/2014)... online in the International Journal of Cancer ... cervical cancer based on findings showing successful reduction in ... discrete population of cells in the cervix. , ... squamocolumnar junction cells, or SCJ cells. These cells reside ... the origins of cervical cancer. A research team co-led ...
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