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Nucleus in Biological Technology

Cochlear Americas Provides Support for Cochlear Implant Recipients to Pursue Higher Education

... "Cochlear Americas is dedicated to empowering our nucleus recipients with an opportunity to pursue higher ... , was born profoundly deaf and received a nucleus cochlear implant at age 2. Emily is enrolled in ... age of 9 months, and at age 4 received her first nucleus cochlear implant. She received a second cochlear ...

Memoirs of a qubit: Hybrid memory solves key problem for quantum computing

... computer memory: storing information inside the nucleus of an atom. This breakthrough is a key step in ... a hybrid system using both the electron and nucleus of an atom of phosphorous embedded in a silicon ... can become rapidly corrupted. This is where the nucleus comes in: when the information in the electron is ...

Positive Preclinical Data on Cell Therapy for Spinal Disc Repair Presented at 23rd Annual Meeting of the North American Spine Society

... disc. In these pre-clinical studies, the disc nucleus from adult pigs was removed and replaced with ... the ability to generate cartilage in the disc nucleus in a predictable and consistent basis," said Dr. ... to be the major cause of back pain, begins in the nucleus and is accompanied by cell death and tissue ...

Genetic manipulation might model cystic fibrosis

... or contained the most common CF-associated mutation (delta-F508). The nucleus of these cells was used to fertilize the eggs of female pigs, and male ... of the CFTR gene in ferret fibroblasts, followed by the transfer of the nucleus of the cells to the eggs of female ferrets was taken by John Engelhardt ...

JCI online early table of contents: March 6, 2008

... or contained the most common CF-associated mutation (delta-F508). The nucleus of these cells was used to fertilize the eggs of female pigs, and male ... of the CFTR gene in ferret fibroblasts, followed by the transfer of the nucleus of the cells to the eggs of female ferrets was taken by John Engelhardt ...

Genetic pathway critical to disease, aging found

... RNA, all-important molecules that carry genetic information from the nucleus of a cell to the cytoplasm where proteins are made. Star-PAP is ... explains, "is like a postage stamp that enables messenger RNA to exit the nucleus of the cell and enter the cytoplasm where the genetic message is ...

UW-Madison scientists guide human skin cells to embryonic state

... by Dolly, the famous sheep cloned in 1996. Dolly was the result of the nucleus of an adult cell transferred to an oocyte, an unfertilized egg. An unknown combination of factors in the egg caused the adult cell nucleus to be reprogrammed and, when implanted in a surrogate mother, develop into ...

Biomimetic-engineering design can replace spaghetti tangle of nanotubes in novel material

... nanotubes. The template for this thermal material's design is a living cell, specifically, the hierarchical protein networks that allow a cell's nucleus to communicate with the cell's outermost regions. "The structure now used when designing materials with carbon nanotubes resembles spaghetti," ...

Researchers develop new way to see single RNA molecules inside living cells

... viral pathogenesis and other biological phenomena. "We are excited to use this imaging strategy to study how single viral RNAs travel from the nucleus of a cell to a virus assembly site, how mRNAs are regulated by location and time, and RNA trafficking in neurons," added Santangelo. ...

Pioneer(R) Surgical Technology, Inc. Wins Frost & Sullivan's 2009 North American Orthopaedic Tissue Engineering Technology Innovation Award

... spinal fusion systems and advanced biologics. Pioneer's signature articulating P3(TM) Technology -- Pioneer PEEK-on-PEEK, is key to the leading nucleus replacement system NuBac(TM) currently in U.S. clinical trials. Pioneer's focus on innovation has resulted in over 100 U.S. and foreign patents with ...

Smallest ever quantum dots bring real world applications closer

... atoms, all the atoms pool their electrons to "sing with one voice", that is, the electrons are shared and coordinated as if there is only one atomic nucleus at the centre. That property enables numerous revolutionary schemes for electronic devices. Research project leader Robert A. Wolkow described ...

Sigma-Aldrich and Sangamo BioSciences Announce the Achievement of Key Throughput Milestone in Research Reagents Agreement

... are the dominant class of naturally-occurring transcription factors in organisms from yeast to humans. Transcription factors, which are found in the nucleus of every cell, bind to DNA to regulate gene expression. Though there are many kinds of transcription factors, only ZFPs are amenable to engineering ...

ISTO Technologies to Present at OneMedPlace Emerging Company Finance Conference

... ET, engineered cartilage to repair and restore joint function in the knee, NuQu(TM), a cell-based injectable formulation of juvenile chondrocytes for nucleus regeneration of the spinal disc and InQu(R), an osteobiologic bone graft Substitute and extender. About ISTO ISTO Technologies, Inc. ...

Frost & Sullivan Acknowledges ISTO Technologies' Role in Developing Advanced Biologic Products for Bone Healing

... in the near future. "The company's development pipeline includes NuQu(TM), a cell-based injectable formulation of juvenile chondrocytes for nucleus regeneration of the spinal disc," notes Ishwarakrishnan. "In addition to this, the company is in clinical trials with DeNovo(R) ET, its scaffold-free ...

Carnegie Mellon MRI technology that noninvasively locates, quantifies specific cells in the body

... MRI detects the nuclear magnetic resonance signal from protons contained in the mobile water in tissue, 19F MRI detects the signal from the nucleus of the fluorine atom. Fluorine is not normally present in the body at sufficient concentrations to detect, so when Ahrens labels cells with PFPE, he ...

SpineMark Appoints Dr. Rudolf Bertagnoli Chairman of International Medical Advisory Board

... invasive spine techniques. Additionally, he is the founder and former president of the Spine Arthroplasty Society (SAS), president of Spine Evolution nucleus Europe (SEN), a member of the North American Spine Society (NASS), a faculty member of IMAST and a past German representative of the International ...

Cochlear Announces Milestone in Hearing Restoration With 120,000 Nucleus(R) Cochlear Implants

... philosophy of a lifetime commitment to those individuals who choose their products. For more information about Cochlear's products, call the Cochlear nucleus Hotline at 800/458-4999 (Voice) or 800/483-3123 (TTY) or visit the website at http://www.cochlear.com . About NYU Langone Medical Center One of ...

Pioneer(R) Surgical Technology, Inc. Announces the Market Launch of the SlimFuse(TM) Anterior Cervical Plate System

... or under clinical evaluation in the United States. Pioneer's signature articulating P3(TM) Technology -- Pioneer PEEK-on-PEEK -- in its NuBac(TM) nucleus replacement device and NuNec(TM) cervical disc, is the most technologically advanced design in the industry. In addition, Pioneer's comprehensive ...

Not the protein, but its location in the cell, determines the onset of leukemia

... the VIB researchers have demonstrated that NUP214-ABL1, a fusion of two proteins, is carcinogenic only when it is in a protein complex near the nucleus of the cell. Located at another place in the cell, NUP214-ABL1 does not lead to cancer. This finding sheds new light on the study of carcinogenic ...

Sangamo BioSciences and Sigma-Aldrich Announce Research and License Agreement With Roche for the Use of ZFN Technology for Generation of Transgenic Animals

... are the dominant class of naturally occurring transcription factors in organisms from yeast to humans. Transcription factors, which are found in the nucleus of every cell, bind to DNA to regulate gene expression. Though there are many kinds of transcription factors, only ZFPs are amenable to engineering ...

Dow AgroSciences Announces Early Exercise of Option for Commercial License With Sangamo BioSciences for Plants

... are the dominant class of naturally occurring transcription factors in organisms from yeast to humans. Transcription factors, which are found in the nucleus of every cell, bind to DNA to regulate gene expression. The ability to selectively control specific genes is emerging as a critical tool in modern ...

Michigan Tech scientist models molecular switch

... at what his analysis of the NDR revealed. Up until the 142-microamp tipping point, the molecule's cloud of electrons had been whizzing about the nucleus in equilibrium, like planets orbiting the sun. But under the bombardment of the higher voltage, that steady state fell apart, and the electrons were ...

Dow AgroSciences, Sangamo BioSciences Announce the Achievement of Key Milestones in Plant Agriculture Collaboration

... are the dominant class of naturally occurring transcription factors in organisms from yeast to humans. Transcription factors, which are found in the nucleus of every cell, bind to DNA to regulate gene expression. The ability to selectively control specific genes is emerging as a critical tool in modern ...

Amnis Announces Release of Its Extended Depth of Field Option for The ImageStream(R) System

... now address is FISH in suspension (FISHIS(R)). Counting FISH spots accurately requires that all spots be in focus, no matter where they are in the nucleus ... EDF technology, combined with the tremendous speed and sensitivity of the ImageStream system, will make high throughput FISHIS a reality. With ...

Laser dissection of depression

... that is known to be of crucial importance for the development of symptoms of depression. This region is 6 mm3 large and is called the Paraventricular nucleus (PVN) since it is situated along the third ventricle of the brain. This brain area is central in the regulations of our normal stress response, while ...

Sangamo BioSciences Announces License Agreement For the Use of ZFP Technology For Generation of Transgenic Animals

... are the dominant class of naturally occurring transcription factors in organisms from yeast to humans. Transcription factors, which are found in the nucleus of every cell, bind to DNA to regulate gene expression. Though there are many kinds of transcription factors, only ZFPs are amenable to engineering ...

Lentigen Corporation Announces Exclusive Licensing Agreement With Case Western Reserve University to Develop Novel Stem-Cell Therapy for Brain Cancer

... the gene or gene silencing sequence is then incorporated into the cell via reverse transcription creating a DNA complex. This complex enters the nucleus incorporating into the chromosomal DNA creating a stable molecule. The gene sequence is integrated in the chromosome and is copied along with the DNA ...

Sangamo BioSciences Announces Expansion of Research and License Agreement With Genentech for ZFP Technology for Protein Pharmaceutical Production

... are the dominant class of naturally occurring transcription factors in organisms from yeast to humans. Transcription factors, which are found in the nucleus of every cell, bind to DNA to regulate gene expression. Though there are many kinds of transcription factors, only ZFPs are amenable to engineering ...

Discovery of a new way to manipulate light a million times more efficiently

... to more accurately measure the movement of sub-atomic particles such as the electron, the tiny negatively-charged entity which moves outside the nucleus of an atom. Attosecond technology may throw light, literally, upon the strange quantum world where such particles have no definite position,only ...

Micromet is Presenting Four Posters on BiTE(R) Antibodies at the International AACR-NCI-EORTC Conference

... with Olivier Gires, Ph.D. at the University Clinic of Munich in Grosshadern, Germany, it was discovered that EpCAM signals into the cell nucleus via pathways known to control the expression of proto- oncogenes (abstract C175). This establishes EpCAM as a signal transducer of cancer cells and ...

Micromet Data Presented at the International AACR-NCI-EORTC Conference Support the Development of Adecatumumab (MT201) in Earlier Stage Cancer Disease Settings

... were presented by Olivier Gires, Ph.D. from the University Clinic of Munich in Grosshadern, Germany, who discovered that EpCAM signals into the cell nucleus via elements of both the notch and wnt pathways (abstract C175). These data not only establish EpCAM as a signal transducer of cancer cells, but ...

Team demos safety of RNA therapy

... RNA, which is a precursor to siRNA. Once the gene is incorporated into the cell's DNA, short hairpin RNA is synthesized and transported from the cell nucleus to the cytoplasm for further processing. The earlier study showed that large amounts of short hairpin RNA blocked the cell's ability to export ...

Benitec MOU With CalbaTech, Inc.

... is about controlling the flow of genetic information. Our genome operates by sending instructions for the manufacture of proteins from DNA in the nucleus of the cell to the protein synthesizing machinery. These instructions are conveyed by messenger RNA (mRNA). In 1998 it was discovered that a certain ...

Biologist who cloned Dolly the sheep believes therapeutic cloning will gain acceptance

... cloning. In the nuclear-transfer process, the nucleus of a somatic cell, a body cell other than a sperm or egg cell, is removed, as is the nucleus of an egg cell. The nucleus of the somatic cell, which contains the ...

Inoculation, Growth & Harvesting in a New Easy-to-Use Disposable Cell Culture System

... should be periodically measured: nucleus Count - Each FibraStage system includes 500 mL ... for estimating the number of cells using the nucleus count method. Aseptically remove a few samples ... the cell population by crystal violet dye (CVD) nucleus count method, which is further described in our ...

Laser Capture Microdissection (LCM) and Expression Profiling of Long-Range Projection Neurons

... to two distant brain regions, the Robust nucleus of the Archistriatum (nucleus RA) and Area X of ... B (CTB) labeled in red or green was injected into nucleus RA or Area X according to standard stereotaxic ... of a 2% solution of CTB was injected into each nucleus RA, which has a volume of about 0.25 mm3. A total ...

Performance of Ad-A-Gene EGFP-MAPKAP-k2: an adenoviral vector gene delivery system

... substrate of p38 MAPK , resides in both the nucleus and cytoplasm in non-stimulated cells. ... of phosphorylated MAPKAP-k2 from the cell nucleus to the cytoplasm. Translocation is thought to ... product, the distribution of MAPKAP-k2 within the nucleus and cytoplasm in response to stimuli can be ...

Performance of Ad-A-Gene EGFP-Glucocorticoid Receptor (EGFP-GCCR): an adenoviral vector gene delivery system

... of the distribution of GCCR within the nucleus and cytoplasm. Cellular distribution of EGFP-GCCR ... fluorescence intensity in the cytoplasm and the nucleus of each cell. The nuclear/cytoplasmic (Nuc/Cyt) ... external stimuli, EGFP-GCCR resides in both the nucleus and cytoplasm (at the “snapshot” time ...

Human cloning plans get blessing from British government

... the genetic information from an unfertilized egg and replace it with the nucleus of a cell from a familial MND patient. Eggs that have successfully received the nucleus containing the MND-causing gene defect will be encouraged to grow up to ...
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