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Mouse in Biological Technology

ALPCO Introduces a Mouse HMW and Total Adiponectin ELISA

... is a departure from other methods for determining mouse HMW adiponectin and was first introduced in a ... oligomers using protease pretreatment, and the mouse HMW Adiponectin ELISA kit reflects a similar ... for its consistency and quality. The new mouse HMW and total adiponectin ELISA has been held to ...

febit First to Offer Newly Published Mouse Genome on a Chip for DNA/RNA Detection and Enrichment

... on the market covering the newly published whole mouse genome. The biochip from febit enables up-to-date ... Heidelberg (Germany) and customer of febit's new mouse biochip, said: "It will be helpful and an advance ... of interest, as demonstrated by the updated mouse genome. This accelerated development will ...

Assessment of safety and efficacy of human embryonic stem cell therapy

... was carried out in the NIH III immune deficient mouse model. Long-term data (spanning the life of the ... chosen for a GLP safety study using the NIH III mouse model, an immune deficient animal model. ... we also showed that vision can be rescued in a mouse model of Stargardt's disease, which is a form of ...

ZyGEM Releases Application Note Showing its DNA Extraction Kits Rapidly Produce High Yields of Quality DNA

... Commercial Kits-- -- Samples Prepared from mouse Tails Using prepGEM(TM) Yielded Over 34 Times the ... DNA and determining precise genotypes from mouse tail samples. Researchers performed extractions ... DNA. "This new application note focusing on mouse genotyping demonstrates that our prep GEM(TM) ...

GeneCopoeia Introduces Genome-Wide MicroRNA (miRNA) Functional Analysis Tools

... cover all known miRNAs for human (750), mouse (450), and rat (270). These lentiviral vector ... UTR) expression clones cover genome-wide human, mouse and rat genes. These expression ready constructs ... number of full-sequence-verified human and mouse full length protein coding ORF cDNA clones , ...

Mouse study reveals genetic component of empathy

... cage with something negative simply by hearing a mouse in that cage respond with squeaks of distress. A genetically different mouse strain with fewer social tendencies did not learn ... Panksepp says. In the experiments, one mouse observed as ...

ExonHit Launches Mouse Genome SpliceArray(TM) for use in Human Disease Modeling Studies

... of its new SpliceArray(TM) for use in studying mouse models of human disease. These SpliceArray(TM) ... nervous system, or immune system disorders. This mouse SpliceArray(TM) products represent the ... our ability to service scientists who use the mouse as a disease model, as well as our own ...

Stem Cell Sciences Enters into Services Agreement with Huntingdon's Disease Research Group, CHDI Foundation Inc.

... to support the standardisation of CHDI's novel mouse embryonic stem (ES) cell lines. CHDI is a US ... of 20 ES cell lines from genetically modified mouse models that mimic aspects of Huntington's disease. These cell lines and mouse models represent an important tool for medical ...

New technique produces genetically identical stem cells

... Wernig and Lengner then took cells from each IPS mouse and introduced the doxycycline trigger, thereby changing the adult mouse cells into IPS cells. While earlier ... identical IPS cells, because all cells in the mouse contain the same number of viral integrations in ...

Sangamo BioSciences Announces License Agreement For the Use of ZFP Technology For Generation of Transgenic Animals

... of research. "Site-specific manipulation of the mouse genome via gene targeting revolutionized biology and enabled the generation of mouse cell-lines and transgenic mouse models of human disease. However, until now, and ...

Allen Institute for Brain Science Launches Three New Landmark Atlas Projects Focusing on the Human Brain, Developing Brain and Spinal Cord

... in the human brain; an atlas of the developing mouse brain designed to illustrate and enhance ... from birth through adulthood; and an atlas of the mouse spinal cord designed to inform research into ... Brain Atlas (ABA)- Human Brain, ABA-Developing mouse Brain, and ABA-Mouse Spinal Cord. Upon ...

JCI table of contents: Dec. 3, 2007

... cancers has been provided by a new study in a mouse model of the disease by Mohammad Athar and ... imatinib at reducing tumor volume and weight in a mouse model of GISTs. As noted by George Demetri from ... patient survival, according to new research in a mouse model of airway (trachea) transplantation from ...

Exelixis Sells 80% Stake in Artemis to Taconic

... and commercialization of genetically engineered mouse models and engineered mouse embryonic stem cells as genetic model systems for ... and distribution of these tailored mouse models to more optimally serve their customers. ...

Caliper Life Sciences Awarded National Institute of Environmental Health Services Contract Valued to $7.0 Million

... Transgenic and Knock-Out mouse Models -- HOPKINTON, Mass., Oct. 3 ... NIEHS investigators with genetically-modified mouse models for research purposes. The NIEHS focuses ... and disease. Working with genetically modified mouse models, including transgenic and gene knockout, ...

Mice teeth explain the troubles with human wisdom teeth

... development in mice. Similarly to human teeth, mouse molars develop from front-to-back so that the ... third, or wisdom tooth. Experiments on cultured mouse molars revealed that the size and number of ... size and number of molars across many other mouse and rat species. They show that the model ...

Taming the anthrax threat

... develop, can prevent illness and death. In mouse studies using DNA microarray technology, the U-M ... emerging in the last decade, to examine mouse macrophage cells infected with the attenuated ... regulates transcription. When they infected mouse cells with a Bacillus anthracis strain altered to ...

Taming the anthrax threat

... develop, can prevent illness and death. In mouse studies using DNA microarray technology, the U-M ... emerging in the last decade, to examine mouse macrophage cells infected with the attenuated ... regulates transcription. When they infected mouse cells with a Bacillus anthracis strain altered to ...

Transposagen Creates a Rat Model of the Human Immune System

... to reduce the likelihood of contracting a fatal infection. The SCID mouse has been one of the most often used animal models in the history of drug ... research," said Dr. Ostertag. Rat models are superior to mouse models for testing the pharmacodynamics and toxicity of potential ...

Time Clocks Technology Catches Up With Crooks

... NSW (PRWEB) July 24, 2009 -- Technology is putting an end to the cat and mouse game of sneaking in late to work - the mouse is caught at the door, in the back room, or on pay day! We rounded up a ...

OMT announces a breakthrough in the development of a novel human antibody platform

... technologies or licensing/fee for service arrangements. Currently, the mouse is the only genetically engineered animal commercially available for the ... and many targets are licensed already. The expense and limitations of the mouse technology create an opportunity for OMT and its new monoclonal antibody ...

AEterna Zentaris: New Data Published on its Ghrelin Antagonist Compound, AEZS-123 (JMV2959), Supports its Use in Alcohol Addiction

... obtained with the administration of AEZS-123, and a ghrelin receptor mouse knockout model, highlights the role of ghrelin to regulate the rewarding value of alcohol in a mouse model of alcohol dependence. When ghrelin's actions are blocked, alcohol's ...

Lixte Biotechnology Holdings' Lead Compound, LB-1.2, Enhances the Effectiveness of Standard Cancer Chemotherapy in Animal Models

... LB-1.2, enhances the effectiveness of two standard chemotherapy drugs in mouse models of human cancers. This research is being conducted under a ... from recovering from DNA-damage produced by standard anti-cancer drugs. In mouse models, LB-1.2 plus Temozolomide caused complete regression without ...

AEterna Zentaris Presents Two Posters on its PI3K Inhibitor Compound, AEZS-126, at AACR Annual Meeting

... of the compound, as well as in vivo pharmacokinetic experiments and mouse xenograft antitumor studies. Results AEZS-126 was identified as ... ion-channels. During the course of in vivo pharmacokinetic experiments and mouse xenograft antitumor studies, the oral bioavailability in mice was ...

Amniotic Fluid May Provide New Source of Stem Cells for Future Therapies

... thymus, and lymph nodes) of the mice were dissected. Transplants using mouse AFKL cells were found to be successful; newly formed white blood cells of ... organs examined after 10-13 weeks. The secondary transplants with mouse AFKL cells were partially successful with some of the mice engrafting the ...

Oncolytics Biotech(R) Inc. Collaborators Present Reovirus Research at Replicating Oncolytic Virus Meeting

... entitled "Combination of Oncolytic Reovirus and Rapamycin in a B16.F10 mouse Melanoma Model." In this study, the investigators examined the in vitro and in vivo oncolytic activity of reovirus against the mouse melanoma cell line B16.F10 in combination with the mTOR inhibitor ...

Sigma-Aldrich Introduces MISSION(R) LentiPlex(TM) Pooled shRNA Libraries to Enable Rapid Whole Genome Screening in Primary Cells, Stem Cells or Tumor Cells

... Pooled shRNA Libraries were developed from the entire TRC-1 human and mouse collections of more than 158,000 shRNA constructs targeting approximately 16,000 human genes and approximately 16,000 mouse genes. Combining Sigma-Aldrich's high-throughput lentiviral production ...

Sangamo BioSciences Initiates Phase 1 Trial of CCR5-ZFP Therapeutic to Treat HIV/AIDS

... of HIV, ZFN-modified CD4 T-cells also preferentially expanded in a mouse model. The modified cells were infused into mice that lack a normal immune ... Researchers determined that ZFN-modified cells engrafted normally in the mouse and that the proportion of modified cells present at the end of the ...

Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice

... online yesterday, RWTH Aachen University researchers demonstrated in a mouse model that the formation of heteromers of the chemokines platelet factor-4 ... diet did not develop chronic arterial inflammation when injected with the mouse version of the CKEY2 peptide. "With the efficacy of the PF4-RANTES ...

Stem Cell Sciences Licenses Stem Cell Technology to Leading Provider of Genetically Modified Models for Pharmaceutical Research

... IRES technology to a leading provider of genetically modified rat and mouse models for medical and pharmaceutical research. Under the terms of the ... in stem cells, which is crucial for the successful creation of transgenic mouse and rat disease models. Dr Alastair Riddell, CEO of SCS, said "A key ...

Vical Reports Third Quarter 2008 Financial Results and Continued Progress in Product Development Programs

... progress was reported over the past few months, including: -- New mouse data with Vaxfectin(R)-formulated seasonal influenza vaccines ... the other type of response, compared with unformulated vaccine; -- A mouse study demonstrating a 100-fold increase in antigen-specific CD8+ T-cell ...

Sangamo BioSciences Presents Data at ICAAC Demonstrating 'In Vivo' Protection Against HIV Infection by CCR5-ZFN Therapeutic

... of HIV, ZFN-modified CD4 T-cells also preferentially expanded in a mouse model. The modified cells were infused into mice that lack a normal immune ... Researchers determined that ZFN-modified cells engrafted normally in the mouse and that the proportion of modified cells present at the end of the ...

Oncolytics Biotech Inc. Collaborators to Present Preclinical Combination REOLYSIN(R) and Cisplatin Research at EORTC-NCI-AACR Annual Meeting

... Anti-Tumour Activity of Oncolytic Reovirus and Cisplatin in a B16.F10 mouse Melanoma Model" is scheduled to be presented October 23, 2008 at the 20th ... increased cell death in vitro compared to either agent alone. In the mouse model, combined therapy suppressed tumour growth and significantly ...

Histogen Launches BioNuesis, the Only All-Human Stem Cell Culturing Kit

... huES cell expansion in culture, without the complications inherent with mouse tumor-derived ECM extracts that are still the best replacement for ... Because current products utilize non-human sources, and can even contain mouse viruses, stem cell therapies developed using these animal products are not ...

Lorus Therapeutics Provides an Update on Progress in Virulizin(R) Development Program

... was that IL-17E itself had significant anticancer activity when used in mouse models of human cancers. Preliminary studies have revealed that IL-17E has ... in a significant induction of the cytokine TNFalpha in tumors in a mouse model of malignant melanoma. Virulizin(R) also stimulated production of ...

Nanocopoeia Licenses New Polymer-Based Biomaterials Platform From the University of Western Ontario

... (abbreviated arbIBS) used by the joint venture NanoInterventions for its mouse Stent Model. He continued, "Given the strong interest that ... model for new coronary stent coatings, using a genetically modified mouse strain with human-like atherosclerosis, a mini- stent, and experimental ...

Sigma-Aldrich Joins Phase 2 of The RNAi Consortium to Validate shRNA Libraries

... lentiviral-based shRNA vector constructs targeting the human and mouse genomes. Sigma-Aldrich's MISSION(R) shRNA portfolio is the exclusive ... targeting more than 16,000 human genes (MISSION TRC-Hs1.0) and 16,000 mouse genes (MISSION TRC-Mm1.0). For more information about the MISSION(R) shRNA ...

New Study Raises Questions About Prostate Cancer Therapies Targeting Insulin-Like Growth Factor Receptor

... manipulating gene expression directly in the epithelial compartment of the mouse prostate gland to better understand the role of IGF-1R. In contrast to ... research showed that eliminating IGF-1R expression in an otherwise normal mouse prostate caused the cells to proliferate and become hyperplastic. Although ...

JCI table of contents: April 22, 2008

... mutated forms of tau found in individuals with FTDP-17 are often used as mouse models of AD. However, Kun Ping Lu and colleagues, at Harvard Medical ... Melbourne Hospital and Monash University, through their analysis of a mouse model of gastric cancer. Specifically, it was shown that the soluble ...

Ocular Biopharmaceutical Company Charlesson Announces $1.6MM in New Funding and Upcoming Presentations at The Association for Research in Vision and Ophthalmology

... a Phase I SBIR award from the NIH to validate and commercialize a genetic mouse model of AMD. "An unmet need currently exists for a reliable genetic model ... efficacy of AMD-therapeutics in development. There are only a few genetic mouse models which have been reported to present with features of AMD, but this ...

SGX Presents Preclinical MET Data at AACR

... tyrosine kinase (MET), inhibits growth of human glioblastoma tumors in a mouse model," was presented in the afternoon poster session entitled Small ... demonstrated potent anti-tumor activity when dosed orally in various mouse models of human cancer including glioblastoma, gastric cancer and lung ...
Other Contents
(Date:9/2/2014)... breast milk is considered the most ideal source ... played a critical role in the evolution and ... human milk contains a large number of bacterial ... phenomenon comes as no surprise to scientists and ... is considered to be the result of co-evolutionary ...
(Date:9/2/2014)... integrity? Tell the truth; everyone has a tipping point. We ... lie if the benefit is great enough. Now, scientists have ... that decision. , The result was published online this ... prefer to be honest, even if lying is beneficial," said ... at the Virginia Tech Carilion Research Institute , where ...
(Date:9/2/2014)... With their long, spiky legs and their propensity for ... stuff of nightmares. And now research from North Carolina ... spread into homes across the eastern United States. , ... or pose any kind of threat to humans," says ... State and lead author of a paper about the ...
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(Date:9/2/2014)... (PRWEB) September 02, 2014 Anti-aging ... products and services such as anti-wrinkle treatments and ... based treatments, and breast augmentation becoming much sought ... by U.S.-based market intelligence firm Transparency Market Research, ... products will grow to USD 191.7 billion by ...
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(Date:9/2/2014)... What happens when you are hospitalized, but your ... arrive at the office for follow-up care, but ... about your hospital stay? Missing or incomplete ... (PCPs) can contribute to poor experiences and lead ... study shows that implementing guidelines can improve hospitals, ...
(Date:9/2/2014)... health risks, including heart disease and diabetes, but University ... mitigate one often-overlooked risk: not buckling up in the ... Jacobson, a professor of computer science and of mathematics, ... a decrease in seatbelt usage. However, these effects can ... "Primary seatbelt laws lead to increased use of seatbelts," ...
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