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Monoclonal in Biological Technology

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

... growth and recurrence." OMP-21M18 is a monoclonal antibody that blocks DLL4 signaling to reduce ... "OMP-21M18 is the first of several promising monoclonal antibodies in development at OncoMed. We have ... About OMP-21M18 OMP-21M18 is a monoclonal antibody optimized to block a key signaling ...

Micromet Closes $80.5 Million Public Offering of Common Stock

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Micromet Receives European Orphan Drug Designation for Treatment of Acute Lymphoblastic Leukemia with BiTE Antibody Blinatumomab

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Micromet Announces Pricing of Public Offering of Common Stock

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Micromet Announces Public Offering of Common Stock

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Micromet, Inc. to Host Conference Call and Webcast to Report Second Quarter 2009 Financial Results on August 6, 2009

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

OMT announces a breakthrough in the development of a novel human antibody platform

... Palo Alto, CA: July 23, 2009 Open monoclonal Technology, Inc. (OMT), in collaboration with ... milestone in the development of OMT's novel human monoclonal antibody platform. "Creating a knockout rat ... available for the generation of human monoclonal antibodies, and many targets are licensed ....

Morphotek(R), Inc. and Cancer Innovations, Inc. Announce Evaluation and Option Agreement for Therapeutic Monoclonal Antibodies

... option agreement in which Morphotek will evaluate monoclonal antibodies targeting certain tumor-associated ... CII provides Morphotek access to several of CII's monoclonal antibodies. Morphotek will evaluate one or more ... portfolio." "CII has developed several monoclonal antibodies, peptides and small molecules with ...

MacroGenics Announces the Initiation of a Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Monoclonal Antibody MGAWN1 in Subjects with Suspected Central Nervous System Infection Due to West Nile Virus

... 2 clinical study evaluating MGAWN1, a humanized monoclonal antibody, for the treatment of individuals with ... About MGAWN1 MGAWN1 is a humanized monoclonal antibody that specifically recognizes the ... built a fully-integrated set of capabilities in monoclonal antibody product development. The company's ...

Morphotek(R), Inc. Announces a Research Collaboration Agreement with Synageva BioPharma Corporation to Develop Potential Treatments for Cancer and Infectious Disease

... Corporation to express and develop therapeutic monoclonal antibodies for the potential treatment of various ... expertise to produce and develop a therapeutic monoclonal antibody. SEP(TM) is an integrated platform of ... specializing in the development of therapeutic monoclonal antibodies; Eisai Medical Research Inc., a ...

Micromet Added to Russell 3000 Index

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Mylan Announces Strategic Collaboration with Biocon to Enter the Global Generic Biologics Market

... partnership. Generic biologics, especially monoclonal antibodies, are expected to become the next great ... our work in generic biologics, especially with monoclonal antibodies, and take it to the next level around ... additional value to Biocon and its shareholders. monoclonal antibodies are emerging as the most dominant ...

Data Presented at Society of Nuclear Medicine 2009 Annual Meeting Supports Potential of Peregrine's Cotara(R) for the Treatment of Brain Cancer

... exposure to other organs. Cotara is a targeted monoclonal antibody linked to a radioisotope being developed ... that links a radioactive isotope to a targeted monoclonal antibody designed to bind to the DNA histone ... company with a portfolio of innovative monoclonal antibodies in clinical trials for the treatment ...

Micromet to Host Conference Call and Webcast to Discuss Blinatumomab Data Presented at EHA on June 8, 2009

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Peregrine Pharmaceuticals Presents Promising Data From Its Phase II Bavituximab Breast Cancer Trial at 2009 ASCO Annual Meeting

... study was 7.4 months. Bavituximab is a monoclonal antibody with a unique anti-cancer mechanism that ... for anti-cancer treatments. Bavituximab is a monoclonal antibody that binds specifically to these ... of bavituximab, a novel anti-phosphatidylserine monoclonal antibody in patients with advanced refractory ...

Micromet Presents Update at ASCO 2009 on a Phase 1b Combination Study of Adecatumumab and Docetaxel

... antibody platform, as well as conventional monoclonal antibodies. BiTE antibodies represent a new class ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM ... with metastatic breast cancer. Micromet's monoclonal antibody MT293, also known as TRC093, is licensed ...

Clinical Data on Peregrine's Bavituximab Cancer Program to Be Discussed in Two Presentations at 2009 ASCO Annual Meeting

... stage biopharmaceutical company developing monoclonal antibodies for the treatment of cancer and ... bavituximab, a novel anti-phosphatidylserine monoclonal antibody in patients with advanced refractory ... About Bavituximab Bavituximab is a monoclonal antibody that binds to the cellular membrane ...

AACR 100th Annual Meeting Highlights Superior Ability of InNexus' DXL-Modified Anti-CD20 Antibody to Attach and Kill NHL With Safety Comparable to Approved Antibody Therapies in Preclinical Studies

... April 20 /PRNewswire-FirstCall/ -- DXL625 monoclonal antibodies appear to be superior to ... company commercializing the next generation of monoclonal antibodies based on its Dynamic Cross Linking ... company commercializing the next generation of monoclonal antibodies based on its DXL technology, which ...

Preclinical Data From Amgen's Oncology Pipeline to be Presented at AACR

... angiopoietins 1 and 2; AMG 479, a fully human monoclonal antibody antagonist of the type 1 insulin-like ... receptor (IGF-1R) and AMG 102, a fully human monoclonal antibody antagonist of HGF, the ligand for the ... pm) -- AMG 479, a fully human anti-IGF-1R monoclonal antibody, inhibits rapamycin-induced Akt ...

Pre-Clinical Data on CEA-specific BiTE Antibody Published in Journal of Immunotherapy Demonstrate Potent Control of Tumor Growth

... well established target antigens of conventional monoclonal antibodies, but also that BiTE antibodies have ... effective anti-tumor approach than conventional monoclonal antibodies. About Micromet, Inc. ... also known as MT201, a traditional human monoclonal antibody that targets EpCAM-expressing solid ...

Human Genome Sciences and Morphotek(R), Inc. Announce Collaboration to Discover, Develop and Commercialize Antibodies for Oncology and Immunology

... discover, develop and commercialize therapeutic monoclonal antibodies in the fields of oncology and ... provided by HGS, generating and developing all monoclonal antibody candidates using proprietary Morphotek ... specializing in the development of therapeutic monoclonal antibodies; Eisai Medical Research Inc., a ...

Micromet, Inc. To Regain Rights to Blinatumomab in North America; Reports Financial Results for the Fourth Quarter and Full Year ended December 31, 2008

... with adecatumumab, an EpCAM-targeting human monoclonal antibody that we develop in collaboration with ... trial with MT203, a GM-CSF-neutralizing human monoclonal antibody, for the treatment of chronic ... phase 1 clinical trial of MT293, a humanized monoclonal antibody targeting denatured collagen, that is ...

Morphotek(R), Inc. Announces Initiation of MORAb-009 Phase II Study in First- Line Treatment of Mesothelioma

... a multi-centered Phase II study of its MORAb-009 monoclonal antibody in mesothelioma. The study will evaluate ... cancer patients." MORAb-009 is a monoclonal antibody that blocks the function of ... in the development of therapeutic monoclonal antibodies; Eisai Medical Research Inc., a ...

PharmAthene Presents Data for SparVax(TM) and Valortim(R), a Novel Vaccine and Anti-Toxin for the Prevention and Treatment of Anthrax Infection at the 7th Annual ASM Biodefense Meeting

... Medarex, Inc. (Nasdaq: MEDX ), is a fully human monoclonal antibody designed to protect against and treat ... course as in humans. Valortim(R), a fully human monoclonal antibody that binds to a distinct epitope on ... Valortim (R) Valortim(R) is a fully human monoclonal antibody designed to protect against and treat ...

OriGene Technologies, Inc. Establishes High Throughput Monoclonal Antibody Production Outsourcing Center in China

... P&A Biotech, a manufacturer and provider of monoclonal antibodies (mAb) to the research community. With ... of its technology center to develop genome-wide monoclonal antibodies to all human proteins. Over the ... proteins are ideal antigens for high throughput monoclonal antibody production. During the last two years, ...

DSM and Crucell Sign Agreement with Bioceros to Serve as Pre-Approved Cell Line Generation Partner of PER.C6(R) Cell Line Proteins

... products such as recombinant proteins, including monoclonal antibodies. Compared to conventional production ... products such as recombinant proteins including monoclonal antibodies. Compared to conventional production ... of protein products, with an emphasis on monoclonal antibodies. Bioceros has a technology platform, ...

Frost & Sullivan Recognizes ESBATech's Innovation in Developing Antibody Fragments for Biologic Therapeutics

... ) Unlike monoclonal antibodies that contain the Fc part of the ... naturally occurring antigen-binding pocket of the monoclonal antibody. This can be advantageous for disease ... improve clinical effects as compared to typical monoclonal antibody therapies, offers the company limitless ...

New Biologic STELARA(TM) Receives Approval in Europe for Treatment of Moderate to Severe Plaque Psoriasis

... (ustekinumab) Ustekinumab is a new, human monoclonal antibody with a novel mechanism of action that ... safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week ... safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week ...

Data Published in Nature Cell Biology Reveal Novel Function of Drug Target EpCAM in Cancer Cell Signalling

... antibody, and adecatumumab (MT201), a human monoclonal antibody. Principal investigator and senior ... phase 1 clinical trial with adecatumumab, a human monoclonal antibody binding to EpCAM, investigating its use ... also known as MT201, a conventional human monoclonal antibody that targets EpCAM-expressing solid ...

Epitomics Appoints Dr. Zhiqiang An as Chief Scientific Officer

... the world's sole provider of humanized rabbit monoclonal antibodies for therapeutic use, today announced ... Epitomics, exclusive maker of RabMAb(R) monoclonal antibodies, is the commercial supplier of rabbit monoclonal antibodies, with customers around the world, ...

Lilly Highlights Transformation Strategy for Wall Street, Reviews Robust Pipeline and Sets 2009 Financial Guidance

... the two studies. -- A-beta Antibody - A monoclonal antibody, the company's A-beta antibody offers ... esophageal. -- IMC-1121B is a fully-human monoclonal antibody that targets the vascular endothelial ... in 2009. -- IMC-A12 is a fully-human monoclonal antibody that targets the insulin-like growth ...

Intellect Neurosciences, Inc. Issues Letter to Shareholders From Its Chairman and CEO

... a pivotal patent related to our ANTISENILIN(R) monoclonal antibody platform in Europe that adds to our ... candidate that has come from our ANTISENILIN(R) monoclonal antibody technology platform is a humanized ... royalty-bearing license to our ANTISENILIN(R) AD monoclonal antibody platform to Wyeth and Elan ...

Medarex And PharmAthene Announce New Therapeutic Data for Anthrax Anti-Toxin, Valortim(R)

... -- Medarex, Inc. (Nasdaq: MEDX ), a leading monoclonal antibody company, and PharmAthene, Inc. (NYSE: ... (NZW) rabbit model. Valortim is a fully human monoclonal antibody generated by Medarex's UltiMAb(R) ... "Therapeutic Efficacy of MDX-1303, an Anti-toxin monoclonal Antibody, for Inhalation Anthrax in the New ...

Laureate Pharma Announces Agreement with Tolera Therapeutics, Inc.

... - Laureate To Manufacture Tolera's monoclonal Antibody Product Candidate - PRINCETON, N.J., ... agreement, Laureate will produce Tolera's TOL101 monoclonal antibody under cGMP conditions to be used in ... of the biopharmaceutical industry: monoclonal antibodies and recombinant protein products. For ...

Pressure BioSciences, Inc. Provides Corporate Update

... technique for the digestion of a therapeutic monoclonal antibody. Amgen scientists reported that, ... provided the most effective method for digesting monoclonal antibodies." 2) Dr. Paul Pevsner Presentation: ... provides a most effective method for digesting monoclonal antibodies; due to scientific and medical ...

Lilly to Acquire ImClone Systems in $6.5 Billion Transaction

... Molecules -- IMC-1121B is a fully-human monoclonal antibody that targets the VEGF receptor to ... may begin in 2009. -- IMC-A12 is a fully-human monoclonal antibody that targets the insulin- like growth ... agents. -- IMC-11F8 is a potent, fully human monoclonal antibody that targets the epidermal growth factor ...

Abeome Forms First Class Scientific Advisory Board

... and years of immunology experience specific to monoclonal antibody development," states Abeome CEO, Mike Wanner. "The company will deploy its monoclonal antibody technology to rapidly develop a pipeline ... to accelerate and improve the development of monoclonal antibodies for life sciences. Abeome owns ...

DSM Biologics and MorphoSys AG to Manufacture Fully Human Antibody

... products such as recombinant proteins including monoclonal antibodies. Compared to conventional production ... production platform for recombinant proteins and monoclonal antibodies. DSM Biologics' FDA-approved facility ... ingredients (API's), mammalian cell production of monoclonal antibodies and proteins, formulation development, ...

MacroGenics Acquires Raven Biotechnologies

... focused on the discovery and development of monoclonal antibody therapeutics for oncology through ... platform, Raven has generated more than 1,300 monoclonal antibodies, including many that target cancer ... commercialize teplizumab, a humanized anti-CD3 monoclonal antibody, as well as other potential next- ...

Access Pharmaceuticals Presents New Data at International Symposium Showing Company's Angiolix(R) Monoclonal Antibody has Potential to Treat Cancer by Attacking Cancer Stem Cells

... gave an oral presentation yesterday on its monoclonal antibody product, Angiolix(R), at the 7th ... treatment and eradication of cancer." Access' monoclonal antibody product, Angiolix, blocks angiogenesis ... uptake mechanism; Angiolix(R), a humanized monoclonal antibody which acts as an anti-angiogenesis ...
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(Date:9/22/2014)... STATION The smell of cut grass in recent ... signalling distress, but new research says the aroma also ... is need for protection, the plant signals the environment ... recognized as a feeding queue for parasitic wasps to ... lay eggs in the pest insect," said Dr. Michael ...
(Date:9/22/2014)... in a plant,s biological clock one that modulates ... , Transcription factors, or genetic switches, drive gene expression ... light, rain, soil quality, or even animals grazing on ... one, called FBH1, that reacts to temperature tweaking ... keeping it on a consistent track. , "Temperature helps ...
(Date:9/22/2014)... YORK CITY (September 22, 2014)The Brain & ... the award of NARSAD Young Investigator Grants ... 200 of the world,s most promising young ... for groundbreaking neurobiological research will seek to ... strategies for psychiatric disorders that affect one ...
Breaking Biology News(10 mins):Mown grass smell sends SOS for help in resisting insect attacks, researchers say 2Mown grass smell sends SOS for help in resisting insect attacks, researchers say 3Genetic switch regulates a plant's internal clock based on temperature 2Brain & Behavior Research Foundation awards 200 NARSAD Young Investigator grants 2
(Date:9/23/2014)... Dennis Thompson HealthDay Reporter ... Coupled with worldwide marches demanding action on climate change, ... weather patterns in the United States may soon exacerbate ... and other heat-related illnesses are expected to increase as ... author Dr. Jonathan Patz, director of the Global Health ...
(Date:9/23/2014)... at Cincinnati Children,s Hospital Medical Center have published ... (EG). The study, published in The Journal ... EG is a systemic disorder that has high ... tract, involves a series of allergy-associated-immune mechanisms and ... distinct from that of a related disorder, eosinophilic ...
(Date:9/23/2014)... a potential source of student diversity for medical ... however, there are significant challenges to enhancing the ... medical schools. The authors recommend that medical school ... be more inclusive of community college students. , ... Francisco and San Jose City College found that, ...
(Date:9/23/2014)... shows that adolescents who suffer from sleep disturbance or ... academically compared to those who enjoy a good night,s ... journal Sleep Medicine . , In a new ... and 19 from Uppsala County, researchers from Uppsala University ... sleep duration (less than 7 hours per day) increased ...
(Date:9/23/2014)... PA (PRWEB) September 23, 2014 If ... ongoing dialysis, dressing for the treatment may be a ... a type of garment that is designed to improve ... patients to receive dialysis without having to remove, tear ... while insuring privacy and preserving their dignity. At the ...
Breaking Medicine News(10 mins):Health News:Health Woes to Worsen Due to Climate Change, Study Warns 2Health News:Health Woes to Worsen Due to Climate Change, Study Warns 3Health News:Advancing the understanding of an understudied food allergy disorder 2Health News:Advancing the understanding of an understudied food allergy disorder 3Health News:Medical students who attended community college likelier to serve poor communities 2Health News:Apparel for Dialysis Patients Invented by InventHelp Client (CBA-2492) 2
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