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Minimal in Biological Technology

Micromet Receives European Orphan Drug Designation for Treatment of Acute Lymphoblastic Leukemia with BiTE Antibody Blinatumomab

... acute lymphoblastic leukemia (ALL) patients with minimal residual disease (MRD)(1). The patients ... ALL cancer cells in their bone marrow - so called minimal residual disease (MRD). Various studies have ... (anti-CD19 BiTE(R)) for targeted therapy of minimal residual disease (MRD) in patients with B ...

Data Presented at Society of Nuclear Medicine 2009 Annual Meeting Supports Potential of Peregrine's Cotara(R) for the Treatment of Brain Cancer

... to brain tumors at high concentrations with minimal radiation exposure to other organs. Cotara is a ... Cotara was concentrated in the brain tumor with minimal exposure to the contralateral healthy brain. The ... have active uptake of radioiodine, showed only minimal uptake of Cotara. Similarly, uptake of Cotara ...

Under the Microscope: 'Micro IVF'

... only oral fertility medications with or without minimal use of injectable gonadotropins when going ... embryo overproduction and multiple births. minimal Stimulation IVF is currently being touted as a ... a 20.8% pregnancy rate after three attempts with minimal Stimulation IVF. Some authors have published ...

New Greenline Tea FASTRACK Solves Cold-Flow Issues

... monoglycerides, sulfur and phosphorus with minimal impact on product yield. "We want to ... provides substantial return on investment with a minimal increase in processing cost. The ability to ... revenue by as much as a factor of two, with a minimal increase in production cost. With capital costs ...

J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology

... Dr. Venter and colleagues begin work on the minimal genome project. This area of research, trying to understand the minimal genetic components necessary to sustain life, ... while the team was doing the research on the minimal genome, the work underwent significant ethical ...

Venter Institute Scientists Create First Synthetic Bacterial Genome

... M. genitalium and beginning work on the minimal genome project. This area of research, trying to understand the minimal genetic components necessary to sustain ... 1995 while the team was doing the research on the minimal genome, the work underwent significant ethical ...

Elagolix Successful in Six Month Lilac Petal Study; Safety and Efficacy Confirmed in Patients With Endometriosis

... Over the six month treatment period, elagolix 150 mg once daily had minimal impact on BMD (-0.80% mean change from baseline, femur; -0.66% mean change ... for Dysmenorrhea and Non-Menstrual Pelvic Pain demonstrated that women had minimal endometriosis pain symptoms at month six (mean scores of approximately 0.5 ...

Photos: FDA Approves 12-Month Labeling Update for EVOLENCE(R) Collagen-Based Facial Filler

... Results are visible and immediate at the time of treatment, with minimal to no bruising or swelling, allowing physician and patient to gauge the ... This collagen structure benefits patients as it is directly linked to the minimal bruising and swelling that might result. EVOLENCE(R) does not use ...

Sigma-Aldrich Introduces MISSION(R) esiRNA for Low Cost, High Specificity Pooled RNAi Screening

... approach of identifying a single siRNA for gene knockdown and ensures minimal off-target effects. "MISSION esiRNA provides a powerful way to ... useful single siRNA is eliminated. In addition, the approach should ensure minimal risk of off-target effects and enables the use of one assay per gene. ...

Video: Schering-Plough Introduces AFRIN(R) PureSea(TM): A Natural, Gentle Nasal Rinse From the Seas of Northern France

... and convenient way to clean nasal passages, because it requires no mixing, minimal cleanup, and stays sterile even after the product is used." The sea ... minerals, and elements to effectively rinse nasal and sinus passages with minimal discomfort or stinging." AFRIN PureSea Nasal Rinse is available in ...

Proteolix Announces Positive Data From Two Ongoing Phase 2 Clinical Trials of Carfilzomib in Multiple Myeloma at the 50th Annual Meeting of the American Society of Hematology

... activity of bortezomib and carfilzomib indicate that carfilzomib has minimal activity on proteases other than the proteasome. In contrast, bortezomib ... inhibition of the proteasome, leading to apoptosis in cancer cells with minimal off-target effects. In Phase 1 and Phase 2 clinical trials, carfilzomib ...

EntreMed Initiates ENMD-2076 Clinical Trial in Multiple Myeloma

... cell lines in vitro. Significant dose-dependent antitumor activity with minimal toxicity was also induced in vivo when ENMD-2076 was administered as a ... cell lines. ENMD-2076 was shown, both in vitro and in vivo, to have minimal toxicity towards human and murine hematopoietic progenitor cells, which ...

Data Presented at ASH Annual Meeting Indicates the Potential of T-Cell Engaging BiTE Antibody Blinatumomab as a Consolidation Treatment for Aggressive Leukemias

... Acute Lymphoblastic Leukemia Show that Blinatumomab is Able to Eliminate minimal Residual Disease BETHESDA, Md., Dec. 8 /PRNewswire-FirstCall/ -- ... regimens, but retain ALL cancer cells in their bone marrow - so called minimal residual disease (MRD). Various reports have confirmed that ALL patients ...

RVX-208 Exploratory Study Illustrates Early Potential for Alzheimer's Disease

... these results trended towards significance versus placebo, even with the minimal number of study subjects. Emerging evidence from large epidemiology ... from the body," stated Dr. Sparks. "Although it was a pilot study, with minimal subjects, we were pleased to find a positive signal and look forward to ...

PEAK Surgical Introduces PlasmaBlade(TM) Product Line Extensions for Use in General Surgery

... that we can cut through all types of tissue quickly and precisely with minimal bleeding and improved surgical incision healing for the patient. With the ... it cuts at a much lower temperature and delivers less heat, we have seen minimal tissue charring and reduced surgical smoke, which is a concern given the ...

Nile Therapeutics Announces Positive Interim Data from Phase 2a Study of CD-NP in Patients with Heart Failure

... these favorable hemodynamic effects of CD-NP were observed with minimal changes in blood pressure relative to baseline. No hypotension or ... of Southern California. "The reduction in PCWP and RAP combined with minimal blood pressure changes and improved urine flow are supportive of CD-NP's ...

Sustainable Oils Receives Regulatory Approval for Feeding Camelina Meal in Livestock Diets

... for biodiesel production. Camelina, a distant relative to canola, requires minimal water and can be harvested with traditional equipment. Because of these ... even on marginal lands, harvested with traditional equipment, and requires minimal water. About Targeted Growth Targeted Growth uses agricultural ...

Renowned NJ-Based Video Assisted Thoracic Surgery (VATS) Team Completes 5,000th Successful Procedure

... surgery (i.e., thoracotomy), this specific technique employs just four minimal incisions and allows surgeons to execute a variety of chest procedures via ... thoracotomy -- A significantly reduced complication rate due to minimal invasion (less than five percent of VATS patients experience ...

PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery

... that it efficiently cut tissue with effective bleeding control and minimal thermal damage compared with standard surgical techniques. The PlasmaBlade ... with a scalpel, while providing the same positive wound healing profile of minimal scarring and inflammation. In addition, surgical incision healing and ...

U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) as the First Medication for Add-On Treatment of Major Depressive Disorder (MDD)

... the 17-item version of the Hamilton Depression Rating Scale (HAMD17), minimal HAMD17 score of 14, and a Clinical Global Impressions Improvement rating of no better than minimal improvement. References (1) Rush AJ, Trivedi MH, Wisniewski SR, et al. ...

HollisterStier Offers Comfort With New ComforTen(TM) Multiple Skin Testing Device

... Provides 10 puncture skin tests at once with minimal patient discomfort SPOKANE, Wash., Nov. 9 /PRNewswire/ -- ... The device features ten surgical steel 1.2mm lancet tips, which create minimal skin trauma for comfortable allergy testing. ComforTen is the only ...

Organon's Asenapine Further Demonstrates Efficacy in Reducing Mania Symptoms for the Treatment of Bipolar I Disorder

... New Data From a Separate Study Also Show minimal Effect on Heart Rhythm Changes in Schizophrenia ... separate safety study, also presented at the ECNP, asenapine demonstrated minimal effect on the QT interval (QTc) -- a measure of the heart's electrical ...

Transave Enters Into Cooperative Research Agreement With NIH To Study ARIKACE(TM) In Nontuberculous Mycobacteria

... based on the successful Phase II results in treating other chronic lung infections, where it demonstrated sustained release in the lung with minimal systemic exposure." About ARIKACE(TM) ARIKACE is a sustained-release formulation of the antibiotic amikacin, which encloses the ...

SAFC Biosciences(R) Defines Hydrolysate Components That Enhance Chinese Hamster Ovary (CHO) Cell Line Protein Production

... biopharmaceutical production processes. The liquid version (Product No. 14700C) is formulated as a 20X concentrated supplement designed to have minimal pH and osmolality impact upon addition. For additional flexibility, a readily soluble dry powder version (Product No. 24700C) is also available. ...

EnVivo Pharmaceuticals Announces Results and Successful Completion of EVP-6124 Phase Ib/IIa Trial at the International Conference on Alzheimer's Disease

... in AD patients was measured using the computerized CogState battery system and a group of traditional 'paper and pencil' cognition tests. minimal treatment-emergent adverse effects were observed during the trial and there were no serious adverse events. Improvement in a number of cognition ...

New Pre-Clinical Data on OmniGuide's BeamPath NEURO(TM) Demonstrates Precise Cutting in Brain Tissue

... the world's first flexible fibers for CO2 laser surgery. BeamPath fibers empower surgeons to perform delicate cutting and coagulation with minimal thermal tissue damage and ultimate maneuverability, a major advantage. "The study conducted by surgeons from the Barrow Neurological Institute, ...

Stanford researchers find a quicker, cheaper way to sort isotopes

... device, cutting costs while achieving an acceptable level of performance, according to Zare's team. Another advantage: the device can be used with minimal training. Existing isotope ratio mass spectrometers can weigh as much as 1500 pounds and occupy the space of a large freezer case, such as those ...

First step to converting solar energy using 'artificial leaf'

... in green leaves, algae and bacteria. The light antennae of bacteria chlorosomes are the fastest of all. They have to be capable of harvesting minimal quantities of light particles in highly unfavourable light conditions, such as deep in the sea. These chlorosomes are made up of chlorophyll ...

Enigma Diagnostics Announces Successful Evaluation of the Enigma FL by the UK's Veterinary Laboratories Agency

... pen-side diagnosis. On-site testing removes delays from transport of samples to the laboratory, which can often take days. The system requires minimal training and its utility for "pen-side" testing for BVD has already been demonstrated.(2) John McKinley, Chairman and CEO of Enigma, stated: ...

YM BIOSCIENCES' SUBSIDIARY RESOLVES PROPOSED ARBITRATION WITH ONCOSCIENCE AG

... of the matters previously in dispute. "We are pleased that CIMYM BioSciences and Oncoscience have resolved their differences amicably at a minimal cost to either party and that each are committed to cooperate fully in moving nimotuzumab forward clinically with all due deliberate speed," said ...

MEDS World, LLC Provides Multiple Environments with Designed Solutions - Wherever People Congregate, MEDS Odor Elimination Solutions Offer Eco-Friendly, Odor-Free Air

... and automotive detailers. Dealerships may elect to bring these solutions in-house, adding revenues to the service drive. Ease of use and minimal training make MEDS products an attractive and inexpensive alternative to improve CSI. All MEDS automotive solutions have been approved by a leading ...

Galichia Heart Hospital Partners with Mobile Surgery International to Develop Wichita-based Center of Excellence with Global Convenience(TM)

... and identifying host surgical facilities. It provides differentiating surgical programs and develops custom solutions to administrative needs with minimal regard to geography. Whether the patient comes to the surgeon, the surgeon goes to the patient, or patient and surgeon meet at a mutually convenient ...

New England Journal of Medicine Study Highlights Need for Rapid, PCR-based Group B Streptococcus (GBS) Testing at Time of Admission for Labor and Delivery

... and automated platform that represents a paradigm shift in the automation of molecular analysis, producing accurate results in a timely manner with minimal risk of contamination. The GeneXpert System is the only system to combine on-board sample preparation with real-time PCR (polymerase chain reaction) ...

ForteBio Launches Two Revolutionary High-Throughput, Label-Free Instruments: The Octet(R) RED384 and the Octet QK384

... of traditional SPR-based systems. Octet biosensors are coated with a proprietary biocompatible matrix that is uniform, non-denaturing and has minimal non-specific binding. ForteBio also announced that the first batch of systems have been purchased by leading pharmaceutical and biotechnology ...

METTLER TOLEDO Introduces an Affordable Reaction Block for Solid Phase Peptide Synthesis (SPPS)

... phase synthesis and parallel purification are reported to produce diverse, drug like library of hindered amides, dipeptides, and tripeptides with minimal purification in parallel arrays. These reactions are effectively performed in the METTLER TOLEDO MiniBlock® with the peptide coupling steps ...

Proteolix Presents Clinical Data from Two Clinical Studies of Carfilzomib in Multiple Myeloma at the 14th Congress of the European Hematology Association

... proteasome inhibitors. Carfilzomib produces specific and sustained inhibition of the proteasome, leading to apoptosis in cancer cells with minimal off-target effects. In Phase 1 and Phase 2 clinical trials, carfilzomib has demonstrated single-agent activity in hematologic malignancies and solid ...

Optimal Reading Services Group, Inc. Receives Investment from Health Evolution Partners

... Optimal enables healthcare delivery organizations to interpret an increased volume of radiology studies with accelerated turnaround times and minimal operational costs. Optimal constructs tailor-made radiology study interpretation services, integrates on- and off-site clinical staffs and ...

Successful Field-Trial Remediation of 1,2-DCA and VC Contaminated Groundwater in Northern Italy

... days, without the accumulation of dead-end catabolites. The use of EHC for ISCR was subsequently chosen for field-scale test, considering its minimal geochemical impact on soil and groundwater conditions. The initial field test area was ca. 50 m2 and the total volume of saturated soil treated was ...

Optimer Pharmaceuticals Announces Lower Recurrence Rates for Fidaxomicin Versus Vancocin(R) in Subgroup Analyses from Its Phase 3 Study for the Treatment of CDI

... resulting in the death of Clostridium difficile . The narrow spectrum profile of fidaxomicin may eradicate Clostridium difficile selectively with minimal disruption to the normal intestinal flora. This may facilitate the return of the normal physiological conditions in the colon and reduce the ...

ForteBio Launches New Assay Capabilities for High-Sensitivity Protein Quantitation and Fragment Screening on Its Octet(R) Platform

... of traditional SPR-based systems. Octet biosensors are coated with a proprietary biocompatible matrix that is uniform, non-denaturing and has minimal non-specific binding. About ForteBio, Inc. ForteBio is a life science company that provides analytical systems to accelerate biotherapeutic ...
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(Date:7/11/2014)... mesenchymal stem cells can stimulate neurogenesis in the brain ... (AD) and improve tissue and function injury under the ... the therapeutic effect of adipose-derived stem cells (ADSCs) transplantation ... oxidative injury and neurogenesis in the brain of AD ... Life Sciences, Tsinghua University, China transplanted ADSCs into the ...
(Date:7/11/2014)... toxins to study the proteins that let nerve cells ... have stumbled upon a biological tactic that may offer ... in a safe and environmentally responsible way. , ... for one species and harmless for a closely related ... pests without harming beneficial species like bees. A summary ...
(Date:7/10/2014)... BEDFORD, Mass. , June 30, 2014  Aware, ... of biometrics software and services, previously announced on June ... a special cash dividend of $1.75 per share, or ... record date of July 10, 2014 and a payment ... notified by NASDAQ that it had set an ex-dividend ...
Breaking Biology News(10 mins):Potent spider toxin 'electrocutes' German, not American, cockroaches 2Potent spider toxin 'electrocutes' German, not American, cockroaches 3NASDAQ Sets Ex-Dividend Date for Aware, Inc.'s Special Cash Dividend of $1.75 Per Share 2
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Breaking Medicine News(10 mins):Health News:New Super Digestive Enzyme, DZ10, Supercharges The Digestion Process 2Health News:Ivyland Medical Center’s Dr. Brad Paddock Offers Tips for Men’s Health 2Health News:Los Angeles Basketball Legend Headed to Dubai 2Health News:Los Angeles Basketball Legend Headed to Dubai 3
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