FDA Approves AstraZeneca's SEROQUEL XR(R) for the Treatment of Bipolar Depression and Bipolar Mania

... 1%), and fatigue (6% vs. 2%).(5) The bipolar mania submission was based on a clinical study of ... was change from baseline in YMRS(**) (Young mania Rating Scale) total score compared to placebo at ... disorder consists of recurring episodes of mania and depression.(2) Bipolar I disorder is ...

Study Suggests Risperidone Long-Acting Injection Combined with Standard Treatment Helped Delay Time to Relapse in Patients with Bipolar Disorder

... (mania) to extreme lows (depression). Signs of mania include euphoria, extreme irritability or rage, ... the treatment of schizophrenia, bipolar mania and the treatment of symptoms associated with ... had no crisis interventions; the subject's Young mania Rating Scale (YMRS) and Montgomery-Asberg ...

Organon's Asenapine Further Demonstrates Efficacy in Reducing Mania Symptoms for the Treatment of Bipolar I Disorder

... 960 adult patients with moderate-to-severe mania associated with bipolar I disorder received ... produced significant mean improvements in mania symptoms versus placebo as measured by changes in YMRS (Young mania Rating Scale) score. The YMRS is an 11-item scale ...

FDA Approves RISPERDAL(R) to Treat Adolescents with Schizophrenia and Children and Adolescents with Bipolar Mania

... 13-17 and for the short-term treatment of bipolar mania associated with manic or mixed episodes ... years and for the short-term treatment of bipolar mania associated with bipolar I disorder in children ... for the treatment of schizophrenia, bipolar mania and irritability associated with ...

FDA Approves PRISTIQ(TM) for the Treatment of Adult Patients with Major Depressive Disorder

... be used cautiously in patients with a history or family history of mania or hypomania. -- Caution is advised in administering PRISTIQ to patients ... hostility, aggressiveness, impulsivity, akathisia, hypomania, and mania have been reported and may represent precursors to emerging ...

SAPHRIS(R) (asenapine) Meets Primary Endpoint in Long-Term Extension Study in Patients With Predominant, Persistent Negative Symptoms of Schizophrenia

... review by the U.S. Food and Drug Administration (FDA) and includes data from a clinical trial program involving more than 3,000 patients in bipolar mania and schizophrenia trials. In Europe, a Marketing Authorization Application (MAA) for asenapine, under the brand name SYCREST(R), is currently under ...

Schering-Plough Submits Response to FDA for SAPHRIS(TM) (asenapine) in the Acute Treatment of Both Schizophrenia and Bipolar I Disorder

... New Drug Application (NDA) for asenapine includes data from a clinical trial program involving more than 3,000 patients in schizophrenia and bipolar mania trials. Schering-Plough is an innovation-driven, science-centered global health care company. Through its own biopharmaceutical research and ...

Phase 3 Data Demonstrate Efficacy and Tolerability of Paliperidone Palmitate, an Investigational Long-Acting Therapy for the Treatment of Schizophrenia

... As the company celebrates its 50th year in mental health, it currently markets prescription medications for the treatment of schizophrenia, bipolar mania and the treatment of symptoms associated with autistic disorder. For more information about Janssen, visit www.janssen.com . J&JPRD and ...

AstraZeneca Submits sNDA for SEROQUEL XR(TM) for the Treatment of Major Depressive Disorder

... adverse events associated with the use of SEROQUEL versus placebo in clinical trials as adjunct therapy with lithium or divalproex in bipolar mania were somnolence (34% vs 9%), dry mouth (19% vs 3%), asthenia (10% vs 4%), constipation (10% vs 5%), abdominal pain (7% vs 3%), postural hypotension ...

Schering-Plough Completes Acquisition of Organon BioSciences

... Asenapine (from Organon), a fast-dissolving, sublingual psychopharmacologic agent for the treatment of patients with schizophrenia and acute mania bipolar disorder; * Corifollitropin alfa (from Organon), a new fertility hormone; * Golimumab, an anti-inflammatory for the treatment of ...

Patient Treatment for Bipolar Disorder Varies Depending on Doctor Specialty; Well Designed Clinical Trials May Be The Answer

... will continue to acquire patient share in all lines of therapy, largely owing to its first-in-class status among the antipsychotics to treat both mania and depression. Janssen's Risperdal and Eli Lilly's Zyprexa suffered the greatest losses, losing a combined 11.9% patient share first line over the ...

Psychologist - technology entrepreneurs frequently experience hypomania

... Hypomania occurs in about 5 to 10 percent. He further explains that mania and hypomania are biologically related as well. Both conditions run ... that a certain combination of genes produces the undesirable disease of mania while a more frequent combination produces the advantageous outcome of ...

Hey Willie, Wisconsin Manufacturing Doesnt Need an Aid Concert!

... capital. Both the jobs and the money were destined to evaporate along with the Internet promise of a New Economy. In the end, the Internet mania joins tulips, railroads and radio in the graveyard of hyperbole. And I say, Good riddance! Let no one misunderstand me! The gut-wrenching process ...

Japan's pharma mergers will trickle to the Midwest

... acquisitions by foreign companies of Japanese foreign companies as well as mergers within Japan: So why is all this Japanese merger mania happening now ? Well, lets start with the Japanese pharma market itself in relationship with the rest of the world. The Japanese pharma market ...

Japanese biotech is booming and linked with Midwest

... Earlier this year, I talked about merger mania in the Japanese pharmaceutical market. Another interesting trend is the growth of Japanese biotechnology. Though the Japanese were slow to ...

Centralization mania takes over

... I don't know if you've noticed but the IT industry is gripped in a mania for centralization right now. If this were fashion, we'd be talking about the new black, but since it's technology, I'll have to settle for saying ...

How to relate to likes of Ballmer, Jobs, and Ellison

... So since they need you as much as you need gainful employment, Gartner's advice is to use this knowledge as a shied whenever their arrogant and edgy mania reaches a fever pitch. "Don't take it personally," Gartner said. "Take a deep breath. Understand it's just him." Clinton-ville In ...

Wisconsin firms won't rush to adopt Microsoft Vista

... with the improved search functions. "It allows for a much deeper search, which is also easier to manage," he said. Adoption advice Vista mania hasn't spread far, and Jaeck and Luter recommend a measured approach to adoption. Outside of Sonic Foundry's engineers and software developers, Jaeck ...