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Lymphocyte in Biological Technology

BioCryst Reports First Quarter 2008 Financial Results and Clinical Update

... showed a dose response effect on reducing lymphocyte counts at doses up to 1040mg administered once ... effects on reduction of peripheral blood lymphocyte counts. Affected lymphocyte subsets in the Phase II study included CD4+, ...

Trubion Announces Acceptance of Three Presentations on Its TRU-016 Product Candidate at the 2009 ASCO Annual Meeting

... and early signs of efficacy of TRU-016 as shown by a reduction in tumor lymphocyte blood counts, reduction in lymph node and spleen size, and/or an ... leukemia cutis, and the other six had 27% to 94% reduction in peripheral lymphocyte count. One patient had an increase in hemoglobin of 40% and a reduction in ...

Sunesis Reports Financial Results for the Second Quarter 2009

... million for the same periods in 2008. Sunesis recognized $2.0 million in the second quarter of 2009 for the sale to SARcode of its interest in the lymphocyte function-associated antigen-1, or LFA-1, patents and related know-how that had previously been the subject of a license agreement with them, and $1.5 ...

Medarex Announces Presentations at Annual Meeting of the American Society of Clinical Oncology

... - Poster discussion from 2:00 p.m. to 6:00 p.m. local time on Sunday, May 31, 2009. "Association of peripheral blood lymphocyte count (ALC) and clinical activity in patients (pts) with advanced melanoma treated with ipilimumab" (Abstract #3020, Developmental Therapeutics: ...

CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies

... in vivo in the mouse. Dendritic cells direct the subsequent immune response to a vaccine by presenting the vaccine's antigen(s) to the appropriate T lymphocyte and then deliver specific cytokine proteins to the T cell to determine the immune response outcome to the specific vaccine. Each L.E.A.P.S. ...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

... characteristics. Dendritic cells direct the subsequent immune response to a vaccine by presenting the vaccine's antigen(s) to the appropriate T lymphocyte and then deliver specific cytokine proteins to the T cell to determine the immune response outcome to the specific vaccine. "L.E.A.P.S. vaccines are ...

Rutgers University Cell and DNA Repository Adopts BioLife Solutions CryoStor(TM) as Standard Biopreservation Media

... world's largest university-based biologics repository, has adopted the Company's CryoStor as the exclusive cryopreservation media for its transformed lymphocyte cell lines (LCL), which are used throughout the world by researchers working to find genetic causes of common, complex diseases such as ...

Kiadis Pharma Reports ATIR(TM) Clinical Data, Further Supporting its Potential in Mismatched Bone Marrow Transplantations

... representing the most promising new developments in the transplantation field, were selected for this Symposium. ATIR(TM), a donor lymphocyte cell based preparation depleted of allo-reactive T-cells, is under development to prevent acute Graft versus Host Disease (GvHD) and allow for early ...

Tolerx Expands Phase 3 'DEFEND' Trial of Otelixizumab in Europe

... is a novel monoclonal antibody being developed for the treatment of type 1 diabetes and other autoimmune diseases. Otelixizumab targets CD3, a T lymphocyte receptor involved in normal cell signaling. Otelixizumab has not yet been approved for marketing. Data suggest that the antibody may work in ...

BioCryst Reports Fourth Quarter and Year End 2008 Financial Results and Provides Corporate Update

... Nucleoside Phosphorylase (PNP) Inhibitor RO5092888 (BCX-4208) in Patients with Moderate to Severe Chronic Plaque Psoriasis: Safety, Tolerability and lymphocyte Effects" was presented at the 50th American Society of Hematology (ASH) Annual Meeting and Exposition, which was held in San Francisco, December 6-9, ...

BioCryst to Present Three Posters During the 50th American Society of Hematology Annual Meeting and Exposition

... Phosphorylase (PNP) Inhibitor RO5092888 (BCX-4208) in Patients wi th Moderate to Severe Chronic Plaque Psoriasis: Safety, Tolerability and lymphocyte Effects (Poster # 2583 ) Sunday, December 7, 2008, 6:00 p.m. - 8:00 p.m. Pacific Time; Hall A In-Vitro Efficacy of the Deoxyguanoside ...

BioCryst Reports Third Quarter 2008 Financial Results and Provides Corporate Update

... phosphorylase inhibitor, met its primary endpoint of safety and tolerability and displayed dose-dependant reductions in peripheral blood lymphocyte counts. The pharmacokinetic and pharmacodynamic results suggest that BCX-4208 may have utility in diseases dependant on T-cells, B-cells ...

Cell Proliferation Assays

... suppress the action of these compounds. Proliferation assays with mixed lymphocyte cultures or MLC's are also commonly used to evaluate the compatibility of ... range of cell numbers used in cell proliferation experiments. A lymphocyte stimulation assay was performed in another experiment on TopCount. Mouse ...

The Bio-Rad Silver Stain, Rev E

... Electrophoresis 3, 2426 (1982) 23. Goldman D et al., lymphocyte proteins in Huntington's disease: quantitative analysis by use ... 71367139 (1985) 36. Kondo I et al., Genetic analysis of human lymphocyte proteins by twodimensional gel electrophoresis: VI. ...

Medical College of Wisconsin ties breast cancer to inflammation

... from six of the non-cancer group. The group found a statistically significant increase in the two proteins in the breast cancer tissue and in lymphocyte tissue. These results demonstrate that both these markers can strongly identify malignant cells and can assist in better diagnosis of breast ...

BD IMag Human Regulatory T Lymphocyte Separation Set for Isolation of Treg Cells

... BD Biosciences is pleased to introduce the BD IMag Human Regulatory T lymphocyte Separation Set DM (Cat. No. 558142) for the isolation of Treg cells from peripheral blood mononuclear cells (PBMC). The reagent set isolates Treg ...

RNAPrep - Total RNA Isolation Purification

... RNAPrep yielded 1.5-3.0 times greater yield than competitors Q & P. Figure 1B. Total RNA isolated from 100 to 1x10 6 3638C lymphocyte cells was used in a TaqMan RT-PCR assay for the beta-actin transcript. Recovery of total RNA using RNAPrep was linear over a 5 ...

Quantification of Nucleosomes in Serum by the Cell Death Detection ELISAplus

... nucleosome-rich standard material was produced by mixing and incubating blood of several individuals, inducing massive apoptosis by mixed lymphocyte reaction. Dilution of the material obtained with incubation buffer (IB) (1:24, 1:32, 1:48, 1:64, 1:96 and only IB) resulted in a linear curve ...
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