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Leukocytes in Biological Technology

Osprey Pharmaceuticals U.S.A., Inc. Completes $11 Million Initial Private Financing

... Osprey Pharmaceuticals U.S.A., a privately-held company focused on developing novel protein therapeutics that selectively target chemokine-activated leukocytes that are responsible for initiating and maintaining inflammatory diseases, announced today that the company has raised $11 million in its first round ...

ProMetic announces Octapharma publication of PRDT'S prion removal resin in Octaplas(R) manufacturing process at 30th International Congress of the International Society for Blood Transfusion meeting in Macao SAR, China

... and monitoring of treatment. Furthermore, the removal of all residual blood cells and neutralization of both allergens and antibodies against leukocytes render this medicinal product virtually free from causing allergic reactions and the risk for transfusion-related acute lung injuries ("TRALI"), ...

Osprey Pharmaceuticals Names Jack M. Anthony as CEO

... are propagated by overabundant and overactive leukocytes. The company's proprietary LPMs selectively and systematically destroy disease-related leukocytes by infiltrating the chemokine system that regulates the movement and activity of leukocytes. The company expects to initiate its first Phase Ib trial ...

Fractionating DNA Fragments Generated by Differential Display PCR

... more acceptable drugs to be developed. As leukocytes play a key role in mediating allergic responses, ... the expression levels of genes in the leukocytes of people suffering from allergic disease as ... with increased expression in the peripheral blood leukocytes of donors suffering from allergic ...

Genomic DNA Extraction from Buffy Coat Using the Perfect gDNA Blood Mini Kit

... Buffy coat is the component of whole blood that contains leukocytes and platelets and makes up only 1% of the entire whole blood ... component enables the researcher to enrich the DNA-containing leukocytes and eliminate the heme-containing red blood cells. The buffy ...

Genomic DNA Extraction from Buffy Coat Using the Perfect gDNA Blood Mini Kit

... Buffy coat is the component of whole blood that contains leukocytes and platelets and makes up only 1% of the entire whole blood ... component enables the researcher to enrich the DNA-containing leukocytes and eliminate the heme-containing red blood cells. The buffy ...

Luminol-enhanced Assay for Superoxide Anion (O2 face="Symbol" )

... that is released into the extracellular environment of stimulated leukocytes (monocytes, macrophages, and polymorphonuclear leukocytes). 1 ... assays. It has many applications including clinical assessment of leukocytes in patients who have altered oxidative means to control infections and ...

Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods

... activation cytokine assay") the endotoxins are detected via mediators (e.g. II 1 , II 6, TNF-a). Thereby mainly monocytes or leukocytes like RAW264.7, MonoMac 6 or THP 1 11 are used. The in-vitro pyrogenic test (IPT) is a patented procedure to detect pyrogenic ...

Oragene and DNA sequencing with ABI PRISM

... DNA from Oragene is reliably sequenced using the ABI PRISM 377 DNA Sequencer. Introduction Blood leukocytes are the traditional source of DNA for molecular testing, but collection is invasive and specimens require infectious precautions. ...

miRNA Expression in White Blood Cells

... blood cells, blood was collected from 14 healthy volunteers. leukocytes were fractionated from whole blood and the total RNA ... Figure 2. Analysis of miRNA Expression in White Blood Cells. leukocytes were collected from 10 ml EDTA-anticoagulated blood samples ...

Enzyme Immunoassay for Studying Intracellular Levels of cAMP

... In addition to Jurkat cells, AC toxin has also been shown to elevate cAMP in monocyte macrophages, 10 polymorphonuclear leukocytes and alveolar macrophages, 11 natural killer cells 12 and HL-60 promyelocytic leukemia cells. 13 Conclusions The EIA cAMP Kit is ...
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