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Kinetic in Biological Technology

ForteBio Launches Two Revolutionary High-Throughput, Label-Free Instruments: The Octet(R) RED384 and the Octet QK384

... mode, while enabling faster time-to-result for kinetic characterization and quantitation measurements. ... instruments enable researchers to perform protein kinetic screening and characterization on a 384-well ... cents range per data point for quantitation and kinetic characterization assays. The new systems are ...

Caliper Launches Small Animal Molecular Imaging System Enabling Real-Time Video Observation

... - New IVIS kinetic System Extends Application Breadth of ... level as they occur in real-time. The IVIS kinetic system utilizes the latest developments in ... in vivo imaging. With the launch of the IVIS kinetic system, researchers are now able to visualize, ...

ForteBio Launches New Assay Capabilities for High-Sensitivity Protein Quantitation and Fragment Screening on Its Octet(R) Platform

... capabilities - available on ForteBio's Octet RED system - by enabling kinetic characterization and screening of fragment libraries that include ... in a standard microplate format. Its biosensors simplify quantitation and kinetic characterization by eliminating throughput limitations of traditional ...

Caliper Life Sciences Reports Fourth Quarter and Full Year 2008 Results

... products, LabChip GX and Zephyr Genomics Workstation, and the new IVIS kinetic imaging system, all launched in the past two quarters. In addition, ... momentum from the LabChip GX, Zephyr Genomics Workstation and IVIS kinetic imaging system, and the expectation that the value of task orders Caliper ...

InterMune to Present Four Abstracts on HCV Protease Inhibitor ITMN-191 at the AASLD Meeting

... other direct anti-viral compounds in development. The safety and viral kinetic profile of ITMN-191 was observed in mono-therapy regimens administered ... systemic circulation of drug. Poster #1861 shows that the strong viral kinetic results reported in abstract #1847 were associated with very low plasma ...

InterMune Reports Second Quarter 2008 Financial Results and Business Highlights

... (MAD) monotherapy trial of ITMN-191: -- Day 14 median viral kinetic results competitive with those published for other direct ... from baseline at Day 14; -- Significant and rapid viral kinetic activity when dosed every 12 hours; and -- Excellent ...

Mergent, Inc. Announces Quarterly Rebalancing of HealthShares(TM) Indexes

... (NASDAQ: CNMD ) GREATBATCH INC (NYSE: GB ) HOSPIRA INC (NYSE: HSP ) kinetic CONCEPTS INC (NYSE: KCI ) OSI SYSTEMS INC (NASDAQ: OSIS ) PALL CORP ... PHARM CO (Tokyo SE: 4530) ISIS PHARMACEUTICALS INC (NASDAQ: ISIS ) kinetic CONCEPTS INC (NYSE: KCI ) KISSEI PHARM CO (Tokyo SE: 4547) KYOWA HAKKO ...

KGI Elects Three New Members to Board of Trustees

... to its Board of Trustees: Catherine M. Burzik, chief executive officer of kinetic Concepts, Inc.; Anthony D. Caracciolo, senior vice president for ... pharmaceutical manufacturing and FDA law." Burzik has served as CEO of kinetic Concepts, Inc. (KCI), a global medical technology company, since November ...

Hill-Rom Announces Sale of Negative Pressure Wound Therapy Intellectual Property

... (NYSE: HRC ) today announced the sale of Hill-Rom's patents and intellectual property relating to Negative Pressure Wound Therapy (NPWT) to kinetic Concepts, Inc. (NYSE: KCI ). Hill-Rom's NPWT portfolio included U.S. and foreign patents and patent applications covering innovations to NPWT ...

Waters Introduces New SYNAPT G2 with Greater Power, Versatility and Speed Than Any Other High-End Mass Spectrometer

... speed, selectivity, and specificity. QuanTof's high field pusher and dual-stage reflectron reduces ion turnaround times associated with pre-push kinetic energy spread while its dual-stage reflectron improves focusing of high energy ions. As a result QuanTof technology provides the highest levels of ...

Evidence of macroscopic quantum tunneling detected in nanowires

... insulators and metals all hinge upon the ability of particles to make it through classically forbidden regions, despite apparently having negative kinetic energy there, as quantum physics allows," Goldbart said. In Newton's world, according to Goldbart, particles would be reflected from such regions. ...

InterMune Reports First Quarter 2009 Financial Results and Business Highlights

... of the six dosage cohorts, and was -5.4 log10 and -5.7 log10 in the best performing q12h and q8h cohorts, respectively. ITMN-191 delivered viral kinetic performance that is comparable to the best results reported to date for other protease inhibitors in similar experiments. There was no ...

AACR 100th Annual Meeting Highlights Superior Ability of InNexus' DXL-Modified Anti-CD20 Antibody to Attach and Kill NHL With Safety Comparable to Approved Antibody Therapies in Preclinical Studies

... were seen to effectively increase the binding strength between the antibody and the target antigen, as determined repeatedly by measurable kinetic changes. InNexus' AACR presentations are titled, " A Novel High Avidity Anti-CD20 With Markedly Increased Cytotoxicity Shows No Systemic Toxicity ...

SeqWright to Invest in LaserGen's Novel Lightning Terminators(TM)

... 3'-hydroxyl group. These Lightning Terminators(TM) exhibit excellent enzymatic properties with commercially available DNA polymerases. In kinetic terms, Lightning Terminators(TM) are more efficient than natural nucleotides, a measure of how fast they are added by and how well they bind to DNA ...

Jubilant Biosys Launches Legend NGSS(TM) Advanced Software Solution for High-Throughput Drug Molecule Screening

... plot heat maps. The novel tool allows flexible and interactive mother to daughter plate mapping from any plate reader. This generates best-fit kinetic and time course assays, without internal IT intervention, complete management of compound and targeted libraries, and optimized on-the fly ...

Elsevier's EMBASE.com Partners With QUOSA

... full-text searching. It has proven an indispensable tool for extracting key information from full text quickly and more easily, for example, kinetic parameters, microarray data, adverse events and toxicity data. In combination with QUOSA Virtual Library, the partnership enables expert searches on ...

InterMune Reports Third Quarter 2008 Financial Results and Business Highlights

... of patients chronically infected with the hepatitis C virus (HCV), ITMN-191. Among the highlights, InterMune reported: - Median viral kinetic results for ITMN-191 competitive with those published for other direct antiviral compounds when used in monotherapy for 14 days in ...

ForteBio, Inc. Closes $25 Million In Series C Financing

... capital-funded company providing analytical systems to accelerate life science and pharmaceutical development. These systems provide quantitation and kinetic information, enabling real-time analysis of biomolecular interactions. ForteBio's analytical capabilities allow significantly easier, faster and ...

InterMune Earns Development Milestone in HCV Protease Inhibitor Collaboration With Roche

... (MAD) monotherapy trial of ITMN-191 in patients chronically infected with HCV genotype 1. ITMN-191 demonstrated significant and rapid viral kinetic activity and excellent safety and tolerability in all dosage regimens. Also in early April, InterMune announced that 13-week preclinical studies in ...

Pelikan Technologies Appoints Denny Ware to Board of Directors

... announced the appointment of Dennert (Denny) Ware to its board of directors. Having most recently served as president and chief executive officer of kinetic Concepts, Inc. (KCI), a global medical technology company, Mr. Ware brings vast operational and relevant industry experience to Pelikan's board. ...

Regenesis Biomedical Advances Corporate Strategy by Appointing Vice President of Marketing

... announced today that Scott Robey joined the company as Vice President of Marketing. Most recently Mr. Robey served as Senior Director of Marketing at kinetic Concepts, Inc (KCI) for the V.A.C.(R) Therapy brand, during the time US product sales grew from approximately $70 million in 2000 to almost $1.0 ...

HC&B Healthcare Launches HC&B Digital

... annual revenue growth since its inception. Capitalized billings for 2007 were $26 million. HC&B's clients, both domestic and global, include kinetic Concepts, Inc. (KCI), Encysive Pharmaceuticals, the Menninger Clinic, Exagen Diagnostics, Inc, Advanced Neuromodulation Systems, Luminex ...

Pharsight Welcomes Newest Japanese PKS, AutoPilot Customer

... and Development Agreement. PKS enables pharmaceutical and biopharmaceutical companies to better manage and control preclinical and clinical kinetic and dynamic data and analyses. Companies use PKS to build pharmacokinetic and pharmacodynamic (PK/PD) data management architecture compliant with FDA ...

MIGENIX releases CEO message #22

... results of this trial are positive, a new drug application (NDA) being submitted for OmigardTM in the first half of 2009; celgosivir Phase II viral kinetic results in the third quarter 2008; CLS001 entering into Phase III clinical development, partnerships; and other progress expected in 2008 and into ...

Knee brace generates electricity from walking

... vehicles, said Arthur Kuo, an associate professor of mechanical engineering at U-M and an author of the paper. Regenerative brakes collect the kinetic energy that would otherwise be dissipated as heat when a car slows down. This knee brace harvests the energy lost when a human brakes the knee after ...

InterMune Announces Fourth Quarter and Full Year 2007 Financial Results and Provides 2008 Guidance

... and that the safety and tolerability results of ITMN-191 were excellent. -- That the trial had achieved its principal goals for viral kinetic performance, safety and tolerability to advance the program into a triple combination study with Pegasys(R) and ribavirin. -- It ...

NovaBay Pharmaceuticals Prices Initial Public Offering of Common Stock

... Alcon, Inc. for use of the Aganocide compounds in the eye, ear and sinus and in contact lens solutions and a license agreement with an affiliate of kinetic Concepts, Inc. for the use of NovaBay's NeutroPhase product in woundcare applications. NovaBay(TM), Aganocide(TM) and NeutroPhase(TM) are trademarks ...

'Radio wave cooling' offers new twist on laser cooling

... zero (-273 C or -460 F) , where it would be essentially motionless and quantum behavior should emerge. Laser cooling is akin to using the kinetic energy of millions of ping-pong balls (particles of light) striking a rolling bowling ball (such as an atom) to slow it down. The RF cooling ...

Endotoxins and their Relevance in R&D ApplicationsLPS Detection & Removal Methods

... Chromogenic End-Point Test kinetic Turbidimetric Test kinetic Chromogenic Test The LAL ... service (using a quantitative, kinetic chromogenic LAL assay). Please inquire ...

Luciferase Reporter Gene Cells and Recombinant Luciferase Dilutions Studied with the CLIPR Luciferase Assay Kit and the LMax Microplate Luminometer (MaxLine Application Note #38)

... low-end standard curve. 2. For the fast kinetic assays, the Lmax was set to inject 100 uL ... 1 mM cAMP for 4 hrs. 2. For the fast kinetic assays, the Lmax was set to inject 100 uL ... to the untreated controls (lower plot). The kinetic profiles were remarkably similar to that of ...

Kinetic determination of vitamin B1

... Abstract kinetic fluorescence as an analytical technique to ... fluorescence and phosphorescence techniques. kinetic fluorescent methods extend the sensitivity ... the reaction mechanism. As an analytical method, kinetic fluorescence establishes a relationship between ...

Measuring RNase Activity A Real-time Kinetic Analysis

... with a fluorometer capable of kinetic analysis, provides a rapid and ... Here we report the steady-state kinetic analysis of RNase A activity using ... proportionality predicted for steady-state kinetic analysis. ...

Preparative Nondenaturing Gel Electrophoresis to Purify NADP-Specific Glutamate Dehydrogenase From Chlorella, Rev B

... kD) composing these holoenzymes are nearly identical; however, kinetic characterization of the enzymes showed them to have strikingly ... 7583 (1963) Bascomb NF and Schmidt RR, Purification and partial kinetic and physical characterization of two chloroplast-localized ...

Purification of Two Isoforms of Pyruvate Kinase from Nordic Krill Using an UNO Q1 Column, Rev A

... PK (PK I and PK II) from this species was required to facilitate kinetic and chromatographic studies of these enzymes relating to seasonal ... Nordic krill does, indeed, exhibit altered physicochemical and kinetic properties with the seasons and may contribute to the ...

Of private equity, research, and drug development

... those in molecular recognition, interact with solvent and especially with water? we find that our current theories - of complex, tightly coupled kinetic networks, of protein-ligand binding of noncovalent interactions and so on simply do not work . Sobering words While in college, I ...

Who is minding the Innovation Gap?

... to actual patient benefit. There are many obstacles along the path from the bench to bedside, and while it is difficult to quantify (in strict kinetic terms) a process which involves multiple parallel, diverging, or converging paths, I would say the major barrier (e.g. the rate-limiting step) is the ...

High Yield Protein Production from Pichia pastoris Yeast: A Protocol for Benchtop Fermentation

... the productivity in bakers yeast cultivation. Biotechnol Bioeng., 18, 1001-1011 Bentley, W. E. and D. S. Kompala. 1989. A novel structured kinetic modeling approach for the analysis of plasmid instability in recombinant bacterial cultures. Biotechnol. Bioeng., 33, 49-61 Komives, E. ...

Promegas Multiplexed Luciferase Reporter and Cell Viability Assays performed on the PHERAstar

... and figure 3). HEK 293 cells were treated with isoproterenol for 5 hours to induce Renilla reporter expression and a correlated kinetic profile of the reporter signal and cell viability were recorded over this time. The EnduRen Live Cell Substrate was added 2 ...

ATP Quantitation in the LMax Microplate Luminometer (MaxLine Application Note #40)

... at room temperature for one hour. 4. The solvent injection system was filled with L/L reagent by pumping 2.0 mL through it. 5. For fast kinetic assay to determine the best settings for endpoint assays, the Lmax was set to inject 100 uL (injector M) L/L reagent into selected samples of ATP ...
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(Date:7/31/2014)... protected 100 percent of animal models against the highly ... causes an intestinal disease that kills approximately 30,000 Americans ... Infection and Immunity . , In the ... against the purified toxins produced by C. difficile ... a laboratory model that mimics the human disease, after ...
(Date:7/31/2014)... better identify and treat those with fibromuscular dysplasia (FMD). ... sized arteries in the body, which can restrict blood flow ... new report appearing in August 2014 issue of ... FMD may not be limited to the arteries as currently ... bones and joints, as well as evidence that inflammation may ...
(Date:7/31/2014)... they are an iconic symbol of tropical resorts ... landscape. Some, like Hawaii,s State Flower- Hibiscus ... relatively few botanists and Hawaiian conservation workers, however, ... related group of plants known as Hibiscadelphus ... Hibiscus species are in fact highly endangered. Until ...
Breaking Biology News(10 mins):C. difficile vaccine proves safe, 100 percent effective in animal models 2Scientists discover biochemical mechanisms contributing to fibromuscular dysplasia 2Brother of Hibiscus is found alive and well on Maui 2
(Date:8/1/2014)... in St. Louis helps explain why brain tumors occur ... than similar tumors in females. For example, glioblastomas, the ... often in males, who suffer greater cognitive impairments than ... researchers found that retinoblastoma protein (RB), a protein known ... male brain cells than in female brain cells. , ...
(Date:8/1/2014)... HealthDay Reporter FRIDAY, Aug. 1, 2014 (HealthDay News) ... have significantly less endurance than those who weigh less, a new ... were obese, half were of normal weight -- people who were ... Obesity also was associated with less strength, increased discomfort and ... to 65 years of age -- neither improved nor reduced a ...
(Date:8/1/2014)... -- Almost 140 people die every year in ... States. But there are several simple ways ... prevention coordinator at Cincinnati Children,s Hospital Medical Center,s ... center news release. "As families begin to ... for parents and children to go over school ...
(Date:8/1/2014)... Summer is here, and with it comes the ... and they can be a pain for dogs. Animal Emergency ... their customers get rid of ticks and prevent them completely. ... the summer, which is why they are so active during ... woodland areas and carry a number of diseases, including lyme ...
(Date:8/1/2014)... and transgender individuals who want to conceive a child ... heterosexual and cisgendered peers, such as reduced fertility, but ... legal challenges to become parents. A comprehensive review of ... presented in the article " LGBT Assisted Reproduction: Current ... LGBT Health , a peer-reviewed journal from Mary ...
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