DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD
... hematopoietic cell transplantation. GVHD is an inflammatory
disease initiated by T cells in the donor graft ... is mediated by a variety of effector cells and inflammatory
cytokines. GVHD presents in both acute and ... Similar to acute GVHD, there is also an inflammatory
condition of the GI tract associated with cGVHD. ...
Schering-Plough Reports Financial Results for 2009 Second Quarter
... Europe of SIMPONI, a novel biologic treatment for inflammatory
diseases. In our industry, long-term strength ... (golimumab), a subcutaneous treatment for certain inflammatory
diseases; SAPHRIS (asenapine), for the acute ... market growth. REMICADE is a treatment for inflammatory
diseases that Schering-Plough markets in ...
DOR BioPharma Announces Publication of orBec(R) Clinical Pulmonary Data in Bone Marrow Transplantation
... an alternative method for treatment of pulmonary inflammatory
disease, that is, the delivery of a potent ... novel pulmonary delivery system in patients with inflammatory
lung diseases will be of interest."
"The ... applications of oral BDP in a number of pulmonary inflammatory
disorders, such as asthma or interstitial lung ...
Knocking the Wind Out of Asthmatics: Help from Hippocrates
... as a way to safely and effectively avoid chronic inflammatory
and allergy like problems, like asthma, perennial ... that interfere with weight loss, and other inflammatory
conditions such as arthritis and migraine, ... reactions to over 300 foods and chemicals. These inflammatory
reactions are linked to chronic health problems ...
Cequent Names F. Stephen Laroux, Ph.D., Director, Immunology and Inflammatory Diseases
... to the new position of director, immunology and inflammatory
diseases, effective immediately. Dr. Laroux ... important in gastro-intestinal diseases, such as inflammatory
bowel disease (IBD). Dr. Laroux's current study ... and treat a wide range of human disorders -- from inflammatory
disease to cancer -- based on the company's ...
UCB and Crohn's Disease Working Group Award $175,000 in Research Grants to Gastroenterology Fellows
... four recipients of the 2009 Research Awards in inflammatory
Bowel Disease (IBD) for Gastroenterology (GI) ... better patient care."
The Research Awards in inflammatory
Bowel Disease for GI Fellows was established in ... programs to people on the front lines of treating inflammatory
bowel disease," said Olav Hellebo, UCB's ...
Resverlogix's Success in Inflammation Program Results in 2 Patents Filed
... research and development (R&D) program for inflammatory
diseases. Two new patent applications have been ... for novel compounds and their use in regulating inflammatory
markers are proteins generated by the body during ...
ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week
... inappropriate immune system response underlying inflammatory
bowel diseases by blocking the CCR9 chemokine ... for the treatment of Crohn's disease and other inflammatory
disorders of the gastrointestinal system. DDW ... Clinical Trials - Immunology, Microbiology & inflammatory
Location: McCormick Place, ...
Roche Venture Fund, Enterprise Ireland Commit EUR3.3 M to Opsona Series B Financing
... preventative approaches to autoimmune and inflammatory
announced that Roche Venture Fund ... advancement of Opsona's clinical trials
diseases such as rheumatoid arthritis, lupus and ... for in-licensing aimed at
treating autoimmune and inflammatory
Commenting on the announcement, ...
ChemoCentryx Identifies Novel Small Molecule C5aR Antagonist
... to specifically target the C5a receptor, a potent inflammatory
mediator and component of the complement system, ... It adds another promising approach to addressing inflammatory
and autoimmune diseases to ChemoCentryx's ... a set of proteins that regulate certain types of inflammatory
responses by the immune system. Fragments of ...
Amira Initiates Phase I Clinical Trial of Novel DP2 Antagonist
... drug candidate for the treatment and control of inflammatory
and allergic diseases linked to the arachidonic ... Development. "We may also explore AM211 in other inflammatory
diseases based on the safety and proof of ... and early development of compounds to treat inflammatory
disease linked to the phospholipid pathways. ...
Health Canada Approves SIMPONI(TM) (golimumab) for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
Psoriatic arthritis is a chronic inflammatory
arthropathy manifesting with
joint pain and ... form of spinal
arthritis, and symptoms of inflammatory
back pain often first present in
people under the ... arthritis, ankylosing
spondylitis is a systemic inflammatory
disease that, in addition to its effect
on the ...
Trubion Pharmaceuticals, Inc. Announces Initiation of Phase 1 Study of SBI-087 for the Treatment of Systemic Lupus Erythematosus (SLE)
... establish category leadership in autoimmune and inflammatory
Trubion ... product candidates to treat autoimmune and inflammatory
diseases and cancer. The company's mission is to ... such as TRU-015 and SBI-087 for autoimmune and inflammatory
diseases, developed under the company's Wyeth ...
Pro Hockey Player Fernando Pisani Looks to Shoot and Score Against Ulcerative Colitis
... another disorder of the digestive tract, are inflammatory
bowel diseases that affect more than one million ... life will help inspire people living with inflammatory
bowel diseases to join the fight in raising ... About Ulcerative Colitis (UC)
UC, a chronic inflammatory
bowel disease affecting nearly 500,000 people in ...
Opsona Therapeutics Closes EUR18M Funding
... and preventative
approaches to autoimmune and inflammatory
diseases, today announced the
completion of an ... advancement of Opsona's clinical trials
diseases, such as rheumatoid arthritis, lupus ... proof of concept studies in patients by
diseases through the innate immune system, with ...
Frost & Sullivan Recognizes ESBATech's Innovation in Developing Antibody Fragments for Biologic Therapeutics
... that has been identified as the cause of many inflammatory
conditions including uveitis, a group of inflammatory
diseases affecting the uvea. To date, the only ... for several indications including uveitis, an inflammatory
condition responsible for an estimated 10 to 15 ...
Axikin Pharmaceuticals Spins out of Actimis
... small molecule therapeutics for respiratory and inflammatory
diseases, today announced a $3 million private ... molecule therapeutics for severe respiratory, inflammatory
and autoimmune diseases such as asthma, chronic obstructive pulmonary disease (COPD), inflammatory
Cequent Names Ted Hibben Chief Business Officer
... activities in three major areas. On our inflammatory
bowel disease (IBD) program, he will look for ... and treat a wide range of human disorders - from inflammatory
disease to cancer - based on the company's ... candidates targeting colon-cancer prevention and inflammatory
bowel disease. The company designed its powerful ...
Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice
... the treatment of a variety of chronic and acute inflammatory
diseases," said Jay Lichter, Ph.D., CEO of ... our work into pre-clinical studies in other inflammatory
disease models," said Josh Schultz, Ph.D., ... exploration of chemokine interactions involved in inflammatory
In addition to targeting ...
Nuvelo Announces Positive Results from Phase 1 Clinical Trial of NU206 in Healthy Volunteers
... such as gastrointestinal (GI) injury, inflammatory
and bone disease," said Dr. Ted W. ... or cancer chemotherapy
induced GI injury, inflammatory
bowel disease, and bone disease.
About ... therapy-induced mucositis and inflammatory
disease. In addition, Nuvelo is pursuing ...
New Data Suggest CIMZIA(R) (Certolizumab Pegol) Active in Treating Moderate to Severe Crohn's Patients With Fistulizing Disease
... -- Data presented this week by UCB at Advances in inflammatory
Bowel Diseases 2008, the Crohn's & Colitis ... life measurements was assessed by the 32-question inflammatory
Bowel Disease Questionnaire (IBDQ), which ... with ulcerative colitis, Crohn's disease is an inflammatory
bowel disease (IBD).
About CIMZIA (R) ...
Portola Data on Its Novel Syk Inhibitors and Novel Universal Factor Xa Inhibitor Antidote to be Presented at 2008 American Society of Hematology (ASH) Meeting
... significant advances in cardiovascular disease, inflammatory
and cancer, today announced that data ... intends to
explore their potential in other inflammatory
diseases and cancers. Portola
is developing its ... over current treatments for cardiovascular and inflammatory
Portola's two lead Phase ...
Morria Biopharmaceuticals Plc Announces Positive Clinical Results for MRX-4 in its Phase II Clinical Study in Allergic Rhinitis Patients
... correlates nicely with the nasal lavage inflammatory
marker data," said
Morria president, Yuval Cohen. ... results regarding MRX-4
modulating the levels of inflammatory
mediators (IL-5, IL-13, MCP-1,
TNF-alpha and ... thereby protecting the cell
agents. Morria is determined to become a ...
Morria Biopharmaceuticals Plc to Present at the Rodman & Renshaw 10th Annual Healthcare Conference
... as well as its
pre-clinical progress in asthma, inflammatory
bowel disease, ophthalmology
and cystic fibrosis. ... the treatment of a variety of acute and
conditions including respiratory, skin, airway and
diseases. For more information please visit
Interleukin Genetics to Present New Findings at the 11th Cardiovascular Genomics and Atherosclerosis Symposium
... and Asian populations relative to inflammatory
Dr. ... Disease
Coronary artery disease (CAD) is an inflammatory
disease in which
plaque builds up inside the ... nutritional compounds for their effects on inflammatory
and other genetic variations, given ...
MedImmune Presents Data Highlighting its Progressive Inflammatory Disease Portfolio at the 72nd Annual Meeting of the American College of Rheumatology
... researchers will present eight posters from its inflammatory
program at the Annual Meeting of the ... - CXCL13 is a molecule that recruits B cells into inflammatory
cell aggregates called follicles. In ... the joint promoting the generation of new inflammatory
follicles and contributing to the disease ....
New Company to Develop Nutritional Interventions Against Chronic Inflammatory and Infectious Diseases
nutritional interventions against chronic inflammatory
diseases. BioTherapeutics Inc. ... in mouse
studies and is linked to chronic inflammatory
or infectious disease
prevention or treatment. ... and
therapeutic interventions against chronic inflammatory
diseases. BioTherapeutics Inc. ...
ChemoCentryx Advances Second Orally Available CCR9 Antagonist CCX025 Into Clinical Development
... of Crohn's disease, ulcerative colitis and
disorders of the gastrointestinal system. This ... known to play a pivotal role in the migration of inflammatory
cells to the digestive tract, resulting in the ... systems in order
to treat autoimmune diseases, inflammatory
disorders and cancer. The
chemokine system is a ...
Morria Biopharmaceuticals Plc Announces Results From its Pre-Clinical Screening of Novel Anti-Inflammatory Compounds
... agent. The assay
measures key inflammatory
mediators, which are released by the ... significantly reduced the levels of the
mediators: GM-CSF (Granulocyte ... Necrosis
Factor alpha), MIP-1 alpha (Macrophage inflammatory
Protein 1 alpha), MCP-1
(Monocyte Chemoattractant ...
Two Luminaries Join Cequent Scientific Advisory Board: Judy Lieberman, M.D. Ph.D., and Patrice Courvalin, M.D.
... familial polyposis, human papilloma
virus, and inflammatory
bowel disease, and their input will be paramount ... and treat a wide range of
human disorders - from inflammatory
disease to cancer - based on the
company's ... targeting colon-cancer prevention and inflammatory
disease. The company designed its powerful ...
Ardea Biosciences to Present Data on Gout and Inflammation Programs at the 2008 ACR/ARHP Annual Scientific Meeting
... Abstract Title: MEK Inhibitor RDEA119 Suppresses inflammatory
Cytokine Production Induced by ... a precursor to trials in patients with inflammatory
diseases. Lastly, we
have evaluated our ... MEK inhibitor for the treatment of
cancer and inflammatory
diseases, RDEA436, in a human ...
Cequent Pharmaceuticals Meets Novartis Option Fund Milestone; Continues to Next Phase to Validate Inflammatory Bowel Disease Targets in Vivo
... simultaneously as potential therapeutics for inflammatory
disease. Our milestone goal, which we ... and treat a wide range of
human diseases -- from inflammatory
diseases to cancer -- based on the
company's ... targeting colon-cancer prevention and inflammatory
disease. The company designed its powerful ...
GlaxoSmithKline and Cellzome Announce Major Strategic Alliance
... of Drug Candidates for inflammatory
LONDON and CAMBRIDGE, England and ... new
generation of kinase-targeted drugs to treat inflammatory
pipeline of small-molecule ... small-molecule kinase inhibitors
targeting key inflammatory
mediators such as PI3Kg and d, Zap-70, Jak3 ...
Osprey Pharmaceuticals U.S.A., Inc. Completes $11 Million Initial Private Financing
... are responsible
for initiating and maintaining inflammatory
diseases, announced today that
the company has ... to yield new high value therapeutics against inflammatory
Osprey Pharmaceuticals ... receptor axis, which play a
significant role in inflammatory
kidney diseases and other autoimmune ...
Vascular Biogenics Ltd. Presented With the Frost & Sullivan 2008 European Gene Expression Targeting Platform Technology Innovation Award
... of small
molecules that specifically target inflammatory
disorders. Moreover, the
company has several ... new family of
anti-inflammatory drugs for chronic inflammatory
diseases, such as
Rheumatoid Arthritis, Multiple Sclerosis, Psoriasis and inflammatory
Disease. VBL has also developed the ...
ViroPharma To Acquire Lev Pharmaceuticals
... therapeutic products for
the treatment of inflammatory
diseases, for $442.9 million of ... is also
implicated in a number of other serious inflammatory
Hereditary angioedema, or C1-INH deficiency, is a dangerous and
potentially deadly inflammatory
disease affecting up to 10,000 patients in
Ardea Biosciences' Advances RDEA806 Into Phase 2a Proof-of-Concept Study for Gout
... -- Dr. Fernando Perez-Ruiz Joins Ardea's inflammatory
Disease Scientific ... from gout,
which is the most common form of inflammatory
arthritis in men over 40.
Gout, also known as ... for the treatment of HIV, cancer and inflammatory
including gout. We have four drug ...
Ardea Biosciences Presents Inflammation Program Data for Arthritis and Gout at 2008 Annual European Congress of Rheumatology
... activation, proliferation and the
production of inflammatory
mediators. Suppression of the ERK pathway ... therapeutic approach for
treating chronic inflammatory
diseases such as rheumatoid arthritis.
RDEA119 is ... support the development of RDEA119 in inflammatory
diseases, we are
currently conducting a Phase 1 ...
Amira Pharmaceuticals Hires Industry Veteran for CFO Position
... discovery and development of
compounds to treat inflammatory
diseases, announced the hiring of Michael
V. ... and
early development of compounds to treat inflammatory
disease linked to the
eicosanoid pathway. Amira ... with GlaxoSmithKline
and Roche in the area of inflammatory
Amira combines the rigor of a big ...
Anesiva and Transcription Factor Therapeutics, Inc. Announce Licensing Agreement for Development and Commercialization of NF-kappa B Clinical Program
... inhibits NF-kappa B, a protein
implicated in the inflammatory
cascade in diseases such as inflammatory
bowel ... of
nuclear factor-kappaB decoy ameliorates murine inflammatory
and restores tissue homeostasis." ... been evaluated for safety,
tolerability and anti- inflammatory
drug effect in an exploratory,
dose-ranging US ...