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Incidence in Biological Technology

Schering-Plough Announces Phase II and III Data for Corifollitropin Alfa

... retrieved was the co-primary endpoint. The incidence of ovarian hyperstimulation syndrome (OHSS) was ... confidence interval (CI) of the difference. The incidence of moderate and severe OHSS was 3.4 percent in ... (including tenderness). They are reported with an incidence between 1% and 6%. About Infertility ...

Human Genome Sciences Reports Positive Long-Term Data for BENLYSTA(TM) (Formerly LymphoStat-B(R)) in Patients With Active Systemic Lupus Erythematosus

... by the safety data presented at EULAR. The incidence rates per 100 patient years of all adverse event ... through four years of treatment. The overall incidence of adverse events (in general and by system organ ... belimumab exposure was 1192 patient years. The incidence rates per 100 patients in all adverse event ...

Pixantrone Significantly Increases Complete Remissions, Overall Response Rates, Frequency of Durable Remissions and Progression Free Survival in Patients with Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

... versus 19.4% on the comparator arm. However, the incidence of grade 3, 4 febrile neutropenia was only 7.4% ... arm. Grade 3, 4 infections had a similar incidence in both study arms (18% vs. 13%). Although the ... (1.5% vs. 1.5%), there was a slightly higher incidence of serious cardiac disorders in patients treated ...

OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer

... indicator of biological effect. - Higher incidence of stable disease (20 patients in OGX-011 plus ... 12 patients in docetaxel arm) with lower incidence of disease progression as best response (1 ... with docetaxel. There was an increase in incidence of mild fever, chills and creatinine levels (a ...

Low Occurrence of Severe Cardiac Side Effects Despite Extensive Prior Doxorubicin Treatment Reported in Pixantrone Pivotal Trial

... reported for doxorubicin. incidence Clinical CHF- related or unrelated to drug ... remission. Pixantrone recipients had a low incidence of severe neutropenia complicated by either fever ... Pixantrone patients also experienced a low incidence of hair loss, a very common side effect of other ...

Bayer and Onyx Announce Nexavar Data Presentations at 45th American Society of Clinical Oncology Annual Meeting

... in 2.4% for Nexavar and 4% in placebo. The incidence of treatment-emergent cardiac ischemia/infarction ... Nexavar vs. 1.3% for placebo. In RCC patients, incidence of bleeding regardless of causality was 15% for Nexavar vs. 8% for placebo and the incidence of treatment-emergent cardiac ischemia/infarction ...

QIAGEN and Chittaranjan National Cancer Institute Partner to Establish First Large-Scale Cervical Cancer Screening Program in Kolkata

... this project as India has the world's highest incidence rate of cervical cancer. We believe that ... The impact of HPV testing on cervical cancer incidence and death in India was demonstrated in an ... the most effective way to reduce cervical cancer incidence when compared to either Pap (cytology) testing or ...

FDA Approves SYMBICORT(R) for Chronic Obstructive Pulmonary Disease (COPD)

... over the 12-month study,(2) and the incidence of pneumonia was no different for SYMBICORT compared to placebo.(2) There was a higher incidence of potential lung infections other than pneumonia ... studies, pneumonia did not occur with greater incidence in the SYMBICORT 160/4.5 group compared with ...

Multiple Vimpat(R) (lacosamide) Studies Presented at American Epilepsy Society Annual Meeting

... and appeared to be dose-related. -- The incidence of weight gain and other troublesome TEAEs such ... and psychiatric AEs appeared low: -- The incidence of somnolence was 7 percent for the ... group vs. 5 percent for placebo -- The incidence of memory impairment was 2 percent for both ...

Human Genome Sciences Announces Albuferon(R) Meets Primary Endpoint in Phase 3 Trial in Chronic Hepatitis C

... events, vs. peginterferon alfa-2a. The incidence of severe and/or serious adverse events was ... alfa-2a treatment group. The incidence of severe and/or serious pulmonary adverse events ... non-inferiority (p=0.0059). The incidence of severe and/or serious adverse events was ...

Synvista Therapeutics Announces Data Further Demonstrating the Value of Haptoglobin Genotyping in Diabetic Patients During AHA Meeting

... also received vitamin E had a significantly lower incidence of MI compared to placebo. Also, HDL function was ... individuals who had received vitamin E, the incidence of MI after stopping vitamin E treatment ... there was little demonstrable difference in the incidence of MI in those Hp2-2 individuals who had received ...

Telik Announces Top-Line Results From Assist-5 Trial of Telcyta(R) in Combination With Pegylated Liposomal Doxorubicin in Platinum Refractory and Resistant Ovarian Cancer

... on the PLD control arm. There was a higher incidence of hematologic adverse events (AEs) in patients ... vomiting, and constipation, were similar in incidence and severity on both arms. Seventeen percent ... the PLD control arm. Telcyta may ameliorate the incidence and severity of stomatitis and PPE known to be ...

Retrospective Analysis of Phase 3 Data Suggest Wyeth's Investigational Compound Bazedoxifene/Conjugated Estrogens Comparable to Placebo on Incidence of Abnormal Mammograms

... estrogens (BZA/CE) may experience incidence of breast tenderness and abnormal mammograms no ... suggested no significant differences in the incidence of breast tenderness or abnormal ... and placebo or raloxifene. In this study, the incidence of treatment-emergent adverse events, serious ...

Indevus Receives Approvable Letter from FDA for NEBIDO(R)

... from clinical studies to determine the precise incidence of serious post-injection oil-based reactions ... intramuscular injection, namely, to reduce the incidence and/or severity of the serious oil-based ... injection technique, has an acceptably low incidence of oil-based reactions to gain approval. In ...

Amylin Pharmaceuticals to Present Promising Data From Diabetes and Obesity Programs at ADA 2008

... was the most frequently reported. The incidence of nausea was higher at the beginning of SYMLIN ... and decreased with time in most patients. The incidence and severity of nausea are reduced when SYMLIN ... BYETTA provides sustained A1C control, low incidence of hypoglycemia when used with metformin or a ...

U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) as the First Medication for Add-On Treatment of Major Depressive Disorder (MDD)

... all) to 10 (extreme). Safety evaluations included incidence of adverse reactions, discontinuation rate due to ... than or equal to 5 percent and at least twice the incidence of placebo plus ADT) associated with the use of ... fatalities, have been reported at an increased incidence in clinical trials of elderly patients with ...

FDA Approves New SPRYCEL(R) (Dasatinib) Product Labeling for Patients with Chronic-Phase CML

... "The new, lower once-daily dose reduces the incidence of some side effects while preserving the ... 100 mg once daily, for chronic-phase CML. incidence of selected adverse reactions (all grades) in the ... months for SPRYCEL and three months for Gleevec. incidence of selected adverse reactions (all grades) in the ...

Clinical Study Findings Show Safety and Procedure Success for TopSpin IntraVascular MRI Catheter for the Coronary Arteries

... The primary endpoint of the study was the incidence of major adverse cardiac events (MACE) at 24 hours. The incidence of MACE at 24 hours was only 0.96% (1 patient), ... of coronary artery disease and reduce the overall incidence of myocardial infarction (heart attack) and ....

New 200 mg Vial for Eloxatin(R) (Oxaliplatin Injection) Offers Greater Convenience and Efficiency of Preparation

... ( patients), which may be fatal. The combined incidence of cough and dyspnea was 7.4% ( FU/LV arm ... the Eloxatin(R) combination arm. The combined incidence of cough, dyspnea, and hypoxia was 43% (7% ... in the Eloxatin(R) combination arm. The incidence of increased bilirubin was similar on both ...

PNH Patients Treated with Soliris(TM) Experienced Dramatic Reduction in Blood Clots During Clinical Trials

... 92 percent reduction in incidence of thromboses CHESHIRE, Conn., Aug. 20 ... (6) Araten DJ, Thaler HT, Luzzatto L. High incidence of thrombosis in African-American and ... (13) Hill A, Platts PJ, Smith A et al. The incidence and prevalence of paroxysmal nocturnal ...

Glenmark's Novel Molecule for Diabetes, Melogliptin to Enter Phase III Trials

... to be the best-in-class in achieving glycemic control with low incidence of hypoglycemia and neutral effect on body weight - Global ... profile. In addition, patients taking Melogliptin experienced low incidence of hypoglycemia and neutral effect on body weight. In this 12-week, ...

Amgen to Participate in Reproductive Health Drugs Advisory Committee Meeting in August

... prostate cancer settings, demonstrated denosumab's ability to reduce the incidence of fractures, and all six studies showed denosumab's ability to increase ... sites measured. In the two pivotal studies with fracture endpoints, the incidence and types of adverse events with denosumab were similar to placebo. The ...

SEP Signs REGURIN(R) Deal

... bladder and increases bladder capacity.[2] It is well tolerated with a low incidence of the common anti-muscarinic side effect, dry mouth.[3],[4] Regurin also does not cross the blood-eye or blood-brain barrier[5],[6],[7] reducing the incidence of confusion in people taking this treatment.[8],[9],[10],[11] ...

AEterna Zentaris to Report Data from Safety Study of Phase 3 Program in Benign Prostatic Hyperplasia with Cetrorelix Ahead of Schedule

... at Weeks 0 and 2, and are followed up to Week 26. The main endpoint is the incidence of possibly drug-related adverse events. More information on this trial ... and long lasting relief of BPH symptoms and was well tolerated, with a low incidence of sexual side effects. Cetrorelix is part of AEterna Zentaris' ...

Valeant Pharmaceuticals Reports Encouraging Final Results With Taribavirin Phase IIb Study

... were fatigue, nausea, flu-like symptoms, headache and diarrhea. The incidence rates for these adverse events among treatment arms were generally comparable except with respect to diarrhea, where incidence of diarrhea was approximately twice as common in patients receiving ...

Multiple Types of Heart Attacks Reduced by Prasugrel in TRITON-TIMI 38 Trial

... Circulation online on May 18, 2009.(2) In this post hoc analysis, the incidence of non-procedural heart attack in patients treated with prasugrel compared ... with 3.4 percent in those taking clopidogrel (p=0.0015). The incidence of PCI-related heart attacks (Type 4) was 4.8 percent in prasugrel ...

InspireMD Announce the Completion of Enrollment for the MAGICAL Trial (MGuard(TM) in Acute Myocardial Infarction) at EuroPCR '09. Results Will be Presented May 21st by Dr. Dariusz Dudek at the InspireMD Cocktail Reception Debate Chaired by Prof. Martin Le

... Dudek, Jagiellonian University, Krakow, Poland). Primary end-points are incidence of complete ST segment resolution measured 60 minutes post procedure and incidence of TIMI 3 flow after PCI. Main secondary endpoints are myocardial blush ...

PharmAthene Presents Data for SparVax(TM), a Novel Vaccine for the Prevention and Treatment of Anthrax Infection, at the 12th Annual Conference on Vaccine Research

... immunological recall following antigenic challenge. In addition, a lower incidence of injection site reactions observed with SparVax(TM) may suggest that it ... responses comparable to the currently licensed product. The lower incidence of injection site reactions observed with SparVax(TM) may indicate that it ...

China Pharma Holdings, Inc. Announces Clinical Trials Already Underway for Candesartan

... China(3). Hypertension is a serious problem and is linked to an increased incidence of other diseases, particularly brain edema, coronary heart disease and ... develops, manufactures, and markets treatments for a wide range of high incidence and high mortality conditions in China, including cardiovascular, CNS, ...

ADVENTRX Provides Update on Strategic Transaction Process

... 80 or other detergents and is intended to reduce the severity and incidence of hypersensitivity reactions. Docetaxel is an anti-cancer agent that acts ... is recommended for docetaxel therapy to reduce the incidence and severity of hypersensitivity reactions. Docetaxel is approved to treat ...

InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF

... 2 and in 31% and 30%, respectively, in CAPACITY 1. In both studies, the incidence of Grade 3 or Grade 4 laboratory abnormalities was similar between ... due to a rash or photosensitivity. There was no difference in the incidence of skin cancer between patients treated with pirfenidone or placebo. ...

Sunesis Pharmaceuticals Provides Year-End Clinical Update on Voreloxin

... study. Voreloxin was generally well-tolerated at 48 and 60 mg/m2, with an incidence of febrile neutropenia of below 10%. An increase in febrile neutropenia is observed at 75 mg/m2, although the incidence remains below 20%. About Voreloxin Voreloxin is a novel ...

ADVENTRX Announces Further Cost-Cutting Measures

... 80 or other detergents and is intended to reduce the severity and/or incidence of hypersensitivity reactions. Docetaxel is an anti-cancer agent that acts ... premedication is recommended for docetaxel therapy to reduce the incidence and severity of hypersensitivity reactions. Docetaxel is approved to treat ...

Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist

... caused by chemotherapy treatment, resulting in a reduction in the incidence of chemotherapy-induced diarrhea. Today, serious gastrointestinal side ... potentially life-threatening side-effect of chemotherapy. Despite its high incidence and severity it is often under recognized and poorly managed: current ...

Indevus Pharmaceuticals Announces Fiscal 2008 Year End and Fourth Quarter Results

... resubmission to address FDA's concerns about the quantification of the incidence of serious cough reactions in clinical trials. The NDA contained a ... a quaternary ammonium structure that may be instrumental in the low incidence of CNS side-effects. At therapeutic concentrations in vitro, SANCTURA does ...

Synvista Therapeutics Announces Availability of Haptoglobin Genotyping Technology at The Annual Scientific Sessions of the American Heart Association

... and another demonstrating that tight glycemic control reduces the incidence of heart attack (myocardial infarction - MI) only in Hp2-2 Diabetes. The ... and who maintained strict glycemic control showed a reduction in the incidence of MI. Study investigators concluded that the Hp2-2 genotype may have ...

Savient's Pegloticase Data in Treatment-Failure Gout Patients Presented at 72nd Annual Meeting of the American College of Rheumatology Conference

... pegloticase every 2 weeks had a statistically significant lower flare incidence and frequency compared to placebo patients in the pooled analysis. ... demonstrated that in Months 4-6 of the GOUT 1 and GOUT 2 studies, the incidence of gout flares in the every 2 weeks dosing group was significantly ...

Custom NX(R) Drug Eluting Stent System Continues to Demonstrate Favorable Outcomes in Challenging Patient Populations at One, Two and Three Years

... Zero incidence of Late Stent Thrombosis Reported in CUSTOM I, II, and III ... Transcatheter Cardiovascular Therapeutics (TCT) meeting. "To date, the incidence of late stent thrombosis in all three CUSTOM trials is zero percent and ...

Lilly to Acquire ImClone Systems in $6.5 Billion Transaction

... electrolytes as necessary Late Radiation Toxicities -- The overall incidence of late radiation toxicities (any grade) was higher with ERBITUX in ... ERBITUX and radiation versus radiation alone arms, respectively - The incidence of grade 3 or 4 late radiation toxicities were similar between the ...

Indevus and FDA Agree on Path Forward for NEBIDO(R)

... appear to provide an adequate size database to determine the precise incidence of serious post-injection, oil-based reactions. Indevus and FDA also ... of testosterone undecanoate intramuscular injection, namely, to reduce the incidence and/or severity of the serious oil- based reactions. Further, Indevus and ...
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(Date:7/27/2014)... patients, scientists have identified more than two dozen ... six that had not been previously reported. The ... partially funded by the National Institutes of Health ... laboratories. , "Unraveling the genetic underpinnings of Parkinson,s ... in this complex disease, and hopefully, may one ...
(Date:7/25/2014)... on the land now called California, and many of ... plants they used for food, fuel, tools, and ritual. ... habitat and natural resources. , Frank Lake, an ecologist ... lead a field trip to the Stone ... America,s 99th Annual Meeting, in Sacramento, Cal. this August. ...
(Date:7/25/2014)... wildfires have been raging this summer and some of the ... In this image collected by the Moderate Resolution Imaging ... a swath of smoke has descended over the Great Lakes ... is the fire image from July 23, 2014 (first image ... as it drifts off southeastward. In the image, it ...
Breaking Biology News(10 mins):NIH scientists find 6 new genetic risk factors for Parkinson's 2Fire ecology manipulation by California native cultures 2Fire ecology manipulation by California native cultures 3
(Date:7/29/2014)... The National Foundation for Infectious ... ASAE Power of A Silver Award winner for ... encourage everyone age six months and older to be ... for its power to enrich lives through its steady ... and professionals about the importance of vaccination. ...
(Date:7/29/2014)... Award-winning inventor Michael Croix has launched an Indiegogo campaign for ... embarrassing odors in the office. PoofPad is a discrete bag ... desk drawer. This compact packaging is designed for ease of ... the pad and poof away! , “We’ve all been there. ... appears out of nowhere. It’s embarrassing and unpleasant for everyone ...
(Date:7/29/2014)... (PRWEB) July 29, 2014 "Acceptance, Recognition, ... man who faced his own demons and wants other men ... intended life partner left. A month later, he had no ... longer pay. When Raymond approached the government for assistance, the ... a two-year counselling program. But this approach didn’t get to ...
(Date:7/29/2014)... Current Back2Basics long-term drug rehab ... foot surgery during his first six months of sobriety. ... twice on one foot, once on the other– which was ... foot a year ago and was prescribed drugs that I ... a friend from home who’d recently completed the program. The ...
(Date:7/29/2014)... Consilium Staffing, Your Partner in Locum Tenens, is reporting ... 2014, with strong indications the Irving, Texas-based firm will reach ... , “This is a great time to be at Consilium,” ... , “We are proud of what we have accomplished in ... more excited about how things are shaping up for the ...
Breaking Medicine News(10 mins):Health News:National Foundation for Infectious Diseases Receives Top ASAE Honors for Keeping the Nation Flu-Focused 2Health News:Award-Winning Inventor Michael Croix Launches an Indiegogo Campaign for PoofPad 2Health News:Award-Winning Inventor Michael Croix Launches an Indiegogo Campaign for PoofPad 3Health News:SBPRA Announces the Release of Its Newest Title, "Acceptance, Recognition, and Control (A.R.C.) Against Depression" 2Health News:Back2Basics Sober Living Resident Overcomes Obstacle in Early Sobriety 2Health News:Consilium Staffing Experiences Significant Revenue Growth 2
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