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Immune in Biological Technology

Transposagen Creates a Rat Model of the Human Immune System

... complete lack of the major components of the immune system. Transposagen will be marketing SCID rats ... offering the SCID rat and other rat models of the immune system in the near future," said Dr. Eric ... viruses from causing serious disease. "This new immune deficiency rat model cannot reject transplanted ...

Oncothyreon announces presentation of long-term Stimuvax data at World Conference on Lung Cancer

... therapeutic cancer vaccine designed to induce an immune response to cancer cells that express MUC1, a ... is thought to work by stimulating the body's immune system to identify and destroy cancer cells ... 3 trial of Stimuvax known as STRIDE (STimulating immune Response In aDvanced brEast cancer) in patients ...

Medicago's H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose

... a single dose of 5 micrograms induced a positive immune response against a new emerging strain of this ... mice where its novel vaccine achieved a positive immune response in 100% of the animals vaccinated ... a continuation of this study, Medicago tested the immune response of its H1N1 vaccine against the ...

ImmuneRegen BioSciences Confirms Homspera's Therapeutic Anti-Influenza Effect on Pandemic H1N1 Influenza Virus After Oral Administration

... hyperthermia associated with infection. immune markers of infection remain to be assessed, but ... support the hypothesized mechanism of Homspera's immune system activation, and expands the therapeutic ... could provide convenient, efficacious immune system augmentation in a number of medical (e.g., ...

Significant Milestone Marks the Beginning of FDA-Authorized Breast Cancer Trial

... cells that can be targeted by the body's own immune system) found in many tumor cell lines or fetal ... which employs OFA to recruit the patient's own immune system to target and attack the cancer cells with ... the patient's cancer cells, thereby generating an immune response with the goal of killing the cancer ...

CEL-SCI Corporation Releases Letter to Shareholders

... has shown that it is possible to stimulate the immune system of cancer patients to increase survival. ... We believe that the key to doing so lies in our immune system. Dendreon's prostate cancer vaccine ... patients not yet treated for their cancer. Their immune system is still intact, except in the area of the ...

Preclinical Proof-of-Concept Studies Published for Novavax Seasonal Influenza Virus-Like-Particle Vaccine

... Virus-Like Particle Vaccine Elicits Protective immune Responses against a Variety of Seasonal Influenza ... "This study demonstrates the breadth of the immune response induced by the VLP vaccine," said Ted ... to future studies to evaluate the breadth of the immune response induced by our VLP-based influenza ...

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... patent application covering its L.E.A.P.S.(TM) immune therapy drugs (vaccines) for the ... together, are expected to induce antigen specific immune response(s) which, based on other L.E.A.P.S. ... models will hopefully lead to a protective immune response. The most recent such ...

Oncothyreon announces initiation of Phase 3 trial of Stimuvax in breast cancer

... The Phase 3 trial, named STRIDE (STimulating immune Response In aDvanced brEast cancer), is ... therapeutic cancer vaccine designed to induce an immune response to cancer cells that express MUC1, a ... is thought to work by stimulating the body's immune system to identify and destroy cancer cells ...

Assessment of safety and efficacy of human embryonic stem cell therapy

... concerns, a study was carried out in the NIH III immune deficient mouse model. Long-term data (spanning ... for powerful drugs to overcome the problem of immune rejection. Until induced pluripotent stem (iPS) ... safety study using the NIH III mouse model, an immune deficient animal model. Importantly, we also ...

Techne Corporation Board Member Recognized

... a dramatically better understanding of the human immune system, in health and in disease. That knowledge ... and innovative ways to harness the power of the immune system to better fight viruses and bacterial ... laureates discovered two new key players in the immune system of the human body: the signal ...

Peregrine Pharmaceuticals Presents Promising Data From Its Phase II Bavituximab Breast Cancer Trial at 2009 ASCO Annual Meeting

... that works by helping to activate the body's own immune system to fight cancer. Bavituximab binds to the ... exposed PS, bavituximab helps mobilize the body's immune system to destroy both the tumors and their ... Once bound, bavituximab alerts the body's immune system to attack the tumor blood vessels, ...

Serial Monitoring With ImmuKnow(R) is Useful in the Risk Assessment of Kidney Transplant Recipients

... Transplant Laboratories. "We recognize that the immune system responds quickly to change and that ... and then as needed when circumstances suggest the immune function is affected." Risk assessment was ... ImmuKnow is a noninvasive biomarker of immune function that assesses ...

Clinical Data on Peregrine's Bavituximab Cancer Program to Be Discussed in Two Presentations at 2009 ASCO Annual Meeting

... is believed to help mobilize the body's immune system to destroy the tumor and the tumor blood ... Once bound, bavituximab alerts the body's immune system to attack the blood vessels, inhibiting ... of evidence supports the active role of PS in immune signaling, with recent research showing that ...

CEL-SCI Developing Immune-Based Treatment Against Swine and Other H1N1 Flu Viruses Using Proprietary L.E.A.P.S. Technology

... lends itself to creating a much more effective immune therapy against the H1N1 flu virus is because the ... conjugates induce an effective and powerful immune response without causing excessive amounts of ... recently the "Avian Flu", patients with stronger immune systems had a greater chance of dying because ...

ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week

... molecule drug that controls the inappropriate immune system response underlying inflammatory bowel ... which is believed to control the inappropriate immune system response underlying inflammatory bowel ... Traficet-EN does not globally suppress the immune system. About the PROTECT-1 Trial ...

Dendreon Reports First Quarter 2009 Financial Results

... suggesting that PROVENGE induces long-term memory immune responses that are durable and can be maintained ... a measure of product potency, is a correlate of immune activation. P-11 is an ongoing Phase 3 clinical ... product candidates designed to stimulate an immune response. Dendreon is also developing an ...

ChemoCentryx Identifies Novel Small Molecule C5aR Antagonist

... certain types of inflammatory responses by the immune system. Fragments of these proteins, such as ... complement fragment C5a, work to recruit immune system cells including neutrophils and ... The C5a receptor is highly expressed on innate immune cells, making it an attractive target for small ...

CEL-SCI's L.E.A.P.S. Technology Shows Potential to Treat Swine Influenza in Preclinical Studies

... recently in avian flu, patients with stronger immune systems had a greater chance of dying because their immune response was too strong (too many proinflammatory ... combines a small peptide that activates the immune system with a small peptide from a ...

Flu vaccine given in microneedle skin patches proves effective in mice

... that the microneedle vaccinations induced strong immune responses against influenza virus that were comparable to immune responses induced by the intramuscular, ... the skin is desirable because of the skin's rich immune network." Even though cutaneous immunization ...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

... combines a small peptide that activates the immune system with a small peptide from a ... to make a vaccine that induces a defined immune response. Dr. Kenneth S. Rosenthal, Professor of ... initiate a protective cell mediated and antibody immune response. These results were obtained for ...

Dendreon Announces Data on PROVENGE Potency and Long-Term Immune Responses in Androgen-Dependent Prostate Cancer

... (sipuleucel-T) induces long-term memory immune responses that are durable and can be maintained ... (APCs), a measure of potency, is a correlate of immune activation. P-11 is an ongoing Phase 3 ... study evaluated CD54 upregulation and peripheral immune responses in men enrolled in the trial. ...

PROVENGE Significantly Prolongs Survival in Men With Advanced Prostate Cancer in Pivotal Phase 3 IMPACT Study

... specifically designed to engage the patient's own immune system against cancer. Detailed results from ... of the long-pursued goal of harnessing the human immune system against a patient's own cancer," continued ... use live human cells to engage the patient's own immune system with the goal of eliciting a specific ...

Tolera Therapeutics Granted Orphan Drug Designation for Organ Transplant Rejection Drug

... specifically target T cells, components of the immune system that play a key role in the rejection, and ... the patient's need for safer and more effective immune suppression therapy. Doctors are in need of alternatives to traditional immune suppression approaches, and the current industry ...

Immunotherapy-Based Provisional Patents Mark Significant Discovery

... immunogen (a cancer target against which the immune system is directed) found in many tumor cell ... FDA-approved trial involves using the body's own immune cells, i.e., the dendritic cells, to recognize ... as a foreign protein and to have them direct the immune system against the cancer cells. The first ...

NIH News Confirms Trend in Stem Cell 'Storage' Facilities, says CEO of San Diego-based Bio-Matrix Scientific Group

... will advance understanding of how blood cells and immune cells are generated. "The findings of NIH ... implications for culturing infection-fighting immune cells outside the body, where they could be ... and other treatments which suppress the immune system. This discovery confirms a new trend for ...

Aethlon Medical Announces Data Supported Strategy to Increase Hepatitis-C (HCV) Cure Rates

... a first-in-class medical device that assists the immune response in combating infectious disease through ... of HCV in circulation and assists to preserve immune cells by removing toxic proteins shed from the ... is a first-in-class artificial adjunct to the immune system proven to capture infectious viruses and ...

Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections

... cells. Exposed PS enables viruses to evade immune recognition and dampens the body's normal ... effects and allow the body to develop a robust immune response to the viral pathogen. Anti-PS ... cellular cytotoxicity, an important anti-viral immune response. Researchers have found that PS is ...

Tolerx Expands Phase 3 'DEFEND' Trial of Otelixizumab in Europe

... to support the development of innovative immune intervention for type 1 diabetes patients. We ... diabetes, is a disorder of the body's immune system. In type 1 diabetes, the immune system attacks and destroys the insulin-producing ...

Quest PharmaTech Announces Results Showing its Photosensitizer, SL052, is an Effective Immuno-Stimulant when combined with Immunotherapy for the Removal of Solid Tumors

... direct local cytotoxicity and induced a systemic immune response, which could enhance its therapeutic ... with cancer vaccines to generate a superior immune response compared with vaccines alone. The study ... or multiple-complementary effectors of the host's immune response to substantially boost the frequency of ...

Implicit Licenses Clinical Stage Antibody Program From Lilly

... infection. CD14 triggers activation of the innate immune response to bacterial components ... pathway. Lung inflammation in response to innate immune activation through the TLR pathway is a ... WA, that develops drugs which modulate the host immune response to disease. Its business model is ...

Opsona Therapeutics Closes EUR18M Funding

... inflammatory diseases through the innate immune system, with our ultimate aim being to uncover ... small molecule products which modulate the innate immune system, which is the key trigger in ... and approaches towards the clinic. The innate immune system represents a new frontier in targeting ...

Sangamo BioSciences Initiates Phase 1 Trial of CCR5-ZFP Therapeutic to Treat HIV/AIDS

... Therapeutic Approach Provides HIV-Resistant immune Cells RICHMOND, Calif., Feb. 3 ... School of Medicine. "The ability to protect immune cells from infection with HIV and the expansion ... that enables HIV to enter and infect cells of the immune system. About ten years ago, it was observed ...

BioMS Medical reports results of exploratory phase II trial of dirucotide in relapsing remitting multiple sclerosis

... testing positive for the HLA-DR2 and/or HLA-DR4 immune response gene; and 64 patients testing negative ... sclerosis (MS), an autoimmune disease caused by immune attack against normal components of the central ... autoimmune process in MS patients with certain immune response genes (HLA types DR2 and/or DR4); MS ...

Frost & Sullivan Recognizes ESBATech's Innovation in Developing Antibody Fragments for Biologic Therapeutics

... contain the Fc part of the antibody that triggers immune responses, antibody fragments consist of only the ... macular degeneration (AMD) and uveitis, where no immune response is required. For this reason, endogenous ... affinity and specificity, but do not require an immune effector response. ESBA105, the company's lead ...

CEL-SCI Corporation Announces 2008 Financial Results

... because that is the period when the anti-tumor immune response can still be fully activated. Once the ... has received radiation and/or chemotherapy, the immune system is severely weakened and is less able to mount an effective anti-tumor immune response. Other immunotherapies are administered ...

Innovative Beverage Products Launches New Product Designed to Enhance the Body's Immune Defense

... now is the time to take steps to help boost your immune system. And Immunity Enhanced Beverage is ... supplement intended to strengthen the body's immune defense, while also reducing the symptoms of the ... from kids to adults, looking to strengthen their immune system and help ward off and/or reduce the pesky ...

Phase III Trial Begins for GAMMAGARD LIQUID Plus rHuPH20 in Primary Immunodeficiency Patients

... or severe hypersensitivity responses to immune Globulin (Human). Patients with severe selective ... result in a severe anaphylactic reaction. immune Globulin Intravenous (Human) products have been ... in blood pressure may occur with infusions of immune Globulin Intravenous (Human). For full ...

Gene against bacterial attack unravelled

... body for many years without being detected by the immune system. The bacteria can suddenly become ... lethal bacteria B. pseudomallei harmless. immune system fooled Wiersinga focussed on the ... receptors which are located on the outside of immune cells, our body's defence system. The toll-like ...

Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections

... cells. Exposed PS enables viruses to evade immune recognition and dampens the body's normal ... effects and allow the body to develop a robust immune response to the viral pathogen. Anti-PS ... cellular cytotoxicity, an important anti-viral immune response. Researchers have found that PS is ...
Other Contents
(Date:4/18/2014)... of researchers led by a University of California, Riverside ... $7.5 million Department of Defense grant to uncover fundamental ... for the predictable design of light-weight, tough and strong ... from plants and animals, including the mantis shrimp, toucan ... have constructed over millions of years and coming up ...
(Date:4/17/2014)... Respiratory syncytial virus (RSV) is a leading cause ... in very young and elderly populations. Despite great ... cells through the fusion protein RSV F, which ... that prevent bundle formation limit RSV infection in ... degradation. In this issue of the Journal ...
(Date:4/17/2014)... Foundation has been named awardee of a three-year ... Defense Spinal Cord Injury Research Program. Gail Forrest, ... double-blinded, controlled, multi-site clinical trial, which will test ... spinal cord injury. Dr. Forrest is assistant director ... Foundation. Two additional sites will participate - the ...
Breaking Biology News(10 mins):Mantis shrimp, toucan and trilobite, oh my 2Mantis shrimp, toucan and trilobite, oh my 3JCI online ahead of print table of contents for April 17, 2014 2JCI online ahead of print table of contents for April 17, 2014 3JCI online ahead of print table of contents for April 17, 2014 4JCI online ahead of print table of contents for April 17, 2014 5JCI online ahead of print table of contents for April 17, 2014 6Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2
(Date:4/18/2014)... The Gerontologist reports that among older ... decrease in anxiety about death and increases in life ... In particular, listening to gospel music is associated with ... in sense of control. , These associations are similar ... of both low- and high-socioeconomic status. , The article, ...
(Date:4/18/2014)... 18, 2014) Benaroya Research Institute at Virginia Mason ... a particular molecule in metastatic breast cancer reduces both ... lung metastases. BRI scientists have found in models of ... by 60 - 80 percent and can keep the ... $1.8 million five-year grant comes from the National Cancer ...
(Date:4/18/2014)... by Northwestern Medicine scientists could lead to potential new ... people with scleroderma. , Fibrosis, or scarring, is ... the skin and lungs can lead to serious organ ... for new therapeutic options centers on findings made by ... identified the role that a specific protein plays in ...
(Date:4/17/2014)... targets that could be used to provide relief ... London made the discovery when researching how pain ... body. , Dr Marzia Malcangio said: "We have ... and our findings could help chemotherapy patients who ... side effect of some chemotherapy drugs (such as ...
(Date:4/17/2014)... of California, San Diego School of Medicine report that ... a recent major loss are more likely to be ... study is published in this month,s issue of the ... compassionate behaviors are associated with better health and well-being ... ways to improve the outcomes of individuals whose deficits ...
Breaking Medicine News(10 mins):Health News:Religious music brings benefit to seniors' mental health 2Health News:Benaroya Research Institute evaluates immunology approach to blocking breast cancer 2Health News:New clues on tissue scarring in scleroderma 2Health News:New pain relief targets discovered 2Health News:The ilk of human kindness 2
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