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Factor in Biological Technology

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

... a gene or DNA vector encoding for a growth factor or any therapeutic protein. The Gene Activated ... production of micro quantities of growth factor proteins or other therapeutic proteins based on ... level of protein required. Growth factor Gene Portfolio ...

Inspiration Biopharmaceuticals Presents Safety Data on IB1001, a Novel Recombinant Factor IX for the Treatment of Hemophilia at the International Society on Thrombosis and Haemostasis (ISTH) Annual Meeting

... on its lead product, IB1001, a novel recombinant factor IX product to treat patients with hemophilia B. ... models and compared to commercially available factor IX products. Results showed that IB1001 has an ... profile when compared to currently available factor IX products. "These results and the ...

Results From Neurotech's NT-501 Phase 2 Retinitis Pigmentosa Studies Demonstrate Consistent Biological Effect on Photoreceptors

... modified to secrete ciliary neurotrophic factor (CNTF). CNTF, a growth factor capable of rescuing and protecting dying ... modified to secrete ciliary neurotrophic factor (CNTF). CNTF is a ...

deCODE and Celera Partner to Expand use of deCODE Risk Markers for Heart Attack, Stroke and Diabetes

... of cardiogenic stroke. Testing for this risk factor provides a new means of identifying stroke ... in TCF7L2 are the most important genetic risk factor yet found for type 2 diabetes(4). ... 4. Grant, et. al., "Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 ...

VIRxSYS Publishes New Study on RNA Therapy

... proteins in animals. With one of these, factor VIII, they showed they could correct hemophilia A ... the principal protein in good cholesterol, and factor VIII, which makes the protein missing in patients ... instructed the liver to make the correct form of factor VIII instead of a mutated form. We also added an ...

Lentigen and Expression Therapeutics Sign Hemophilia Co-Development Agreement

... a biotechnology company specializing in factor VIII-based therapeutics, today announced a ... clotting disorder caused by a mutation in the factor VIII gene resulting in a deficiency of factor VIII protein. Lentigen and Expression ...

Plasmonic whispering gallery microcavity paves the way to future nanolasers

... on surface plasmons can have a large quality factor and can thereby enable ultra-small device ... the lasing cavity - a laser cavity with a high-Q factor has a low power loss. Enter the whispering ... which Cal Tech's Vahala has used to boost the Q factor of dielectric microcavities. Whispering galleries ...

Portola Data on Its Novel Syk Inhibitors and Novel Universal Factor Xa Inhibitor Antidote to be Presented at 2008 American Society of Hematology (ASH) Meeting

... and cancers. Portola is developing its universal factor Xa inhibitor antidote to neutralize the effect of small molecule factor Xa inhibitors in patients experiencing ... PM 2006-2008 - West (Moscone Center) factor Xa Inhibitor Antidote "Recombinant ...

Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy

... that measuring the genetic risk factor on chromosome 9p21 detected by the deCODE MI(TM) ... test to enable clinicians to measure this risk factor as part of their efforts to provide the ... the clinical utility of testing for the 9p21 risk factor by adding it to a range of standard CHD risk ...

Cardium Reports on Third Quarter 2008 Financial Results and Revised Business Strategies for Operating Units

... tadenovec, Ad5FGF-4) is a DNA-based growth factor therapeutic being developed for potential use by ... (TRC) is focused on the development of growth factor therapeutics for the treatment of severe chronic ... tadenovec, Ad5FGF-4) is a DNA-based growth factor therapeutic being developed for potential use by ...

Biomoda, Inc. (BMOD) SqueezeTrigger Price is $0.27. Approximately 1 Million Shares Shorted Since November 2006 According to Buyins.net Research Report

... for covers. Market Maker Friction factor is shown in the chart below: Date Change ... 0.00% 0 0 Analysis of the Friction factor chart above shows that in the 4 trading days ... a normal market in shares of BMOD. The Friction factor displays how many more shares of buying than ...

Portola Pharmaceuticals Initiates Phase II Trial of Betrixaban, its Novel Oral Factor Xa Inhibitor for Stroke Prevention in Atrial Fibrillation

... apixaban and dabigatran. Betrixaban inhibits factor Xa, a validated target for which there are approved drugs on the market. Inhibiting factor Xa activity appears to offer advantages over ... of drug-drug interactions often seen with other factor Xa inhibitors in development and with warfarin. ...

Lilly to Acquire ImClone Systems in $6.5 Billion Transaction

... antibody that targets the epidermal growth factor receptor (EGFR), the same receptor targeted ... and tumor cells called the epidermal growth factor receptor (EGFR, HER1, c-ErbB-1). In vitro assays ... metalloproteinase and vascular endothelial growth factor production. In vitro, ERBITUX can ...

New Recombinant XYNTHA Now Available for Patients with Hemophilia A

... have begun for XYNTHA(TM) Antihemophilic factor (Recombinant), Plasma/Albumin-Free, a new recombinant factor VIII product for both the control and prevention ... Shipments of the Company's current recombinant factor VIII product, ReFacto(R) ...

CSL Behring's Innovative HeliTrax(SM) System Helps Physicians Manage Hemophilia A Patients

... A patients who use Helixate(R) FS, Antihemophilic factor (Recombinant), and their treatment providers are ... her 10-year-old son Tyler's severe hemophilia and factor VIII deficiency since October 2007. "I love ... Helixate(R) FS Helixate(R) FS is a recombinant factor VIII treatment for hemophilia A that offers ...

Video: CSL Behring Provides $1.2M Grant for World's First Study of Postpartum Women with VWD, Common Bleeding Disorder

... by a deficiency or abnormality of von Willebrand factor in the blood. According to the U.S. Centers ... they give birth." In all women, von Willebrand factor (VWF) and factor VIII (FVIII) levels increase throughout the third ...

Pharmacyclics Reports Fourth Quarter and Fiscal 2008 Financial Results

... associated with the company's factor VIIa inhibitor program due to the completion of ... of lymphomas and the filing of an IND for our factor VIIa inhibitor," said Richard A. Miller, M.D., ... PCI-27483, a small molecule inhibitor of factor VIIa being developed both for the ...

AMT Starts Collaboration With St. Jude Children's Research Hospital on Gene Therapy for Hemophilia B. Company Accesses Exclusive Commercial Rights to Final Therapy

... Nathwani, M.D., Ph.D., who initiated his work on factor IX while in Nienhuis' lab, has continued to ... AAV vector that produces therapeutic levels of factor IX when given intravenously in animal models. This vector has been licensed to AMT. Repair factor IX production and blood clotting Hemophilia B ...

Genzyme Files Applications for Approval of Mozobil in the United States and Europe

... who received Mozobil in conjunction with a growth factor achieved more rapid and effective mobilization of ... transplant than patients treated with growth factor alone. In addition, more patients treated with Mozobil plus a growth factor achieved a composite endpoint of optimal stem ...

AMT Makes Important Advance in the Development of its Gene Therapy for Hemophilia B -Company Accesses Technology to Prevent Immune Response

... blood clotting due to an absence of clotting factor Factor IX. Gene therapy can be used to introduce the gene that produces factor IX and thereby repair blood clotting. AMT will ... an immune response against the newly formed factor IX, which the patient's body may recognize as ...

Anesiva and Transcription Factor Therapeutics, Inc. Announce Licensing Agreement for Development and Commercialization of NF-kappa B Clinical Program

... drug candidate Avrina(TM), to Transcription factor Therapeutics, Inc. (TFT). NF-kB Transcription factor Decoy inhibits NF-kappa B, a protein implicated ... http://www.anesiva.com . About Transcription factor Therapeutics TFT is an Irvine, California based ...

NIMOTUZUMAB CLINICAL DATA PRESENTED AT ASCO ANNUAL MEETING

... antibody that targets the epidermal growth factor receptor, were presented at the 2008 ... study of Nimotuzumab, an anti epidermal growth factor receptor (EGFR) monoclonal antibody (MAb), in ... that targets the epidermal growth factor receptor (EGFR) and is approved in several ...

Senesco Technologies Reports Third Quarter Fiscal 2008 Financial Results

... interfering RNA (siRNA) against Senesco's factor 5A technology, the data showed what Senesco ... Treated mice were injected intratumorally with factor 5A therapy encapsulated in nanoparticles, ... mice received a nanoparticle without the factor 5A therapy. One of the dosing regimens ...

Stable Stroke Patients More Likely to Die From a Nonstroke Cardiovascular Event Than a Further Stroke

... High blood pressure is a risk factor strongly associated with stroke. CVD is a global ... worldwide. This underscores the very high risk factor profile and high percentage of CVD patients with ... of the legs -- PAD -- a significant risk factor for heart attack or stroke. Atherothrombosis is ...

Regado Biosciences' REG1 Anticoagulation System Study Results Published in the Journal of Thrombosis and Haemostasis

... and safety study of an antidote-controlled factor IXa inhibitor," was authored by Mark Y. Chan, ... dose of RB006 resulted in essentially complete factor IXa inhibition. The studies also demonstrated an ... selectively and potently binds to and inhibits factor IXa, a protein that is critical to blood ...

China Biologic Products Announces SFDA Approval for the Production of Cryoprecipitate and for the Clinical Trial of Human Prothrombin Complex

... the use in the production of Human Coagulation factor VIII, a coagulation treatment for hemophilia and ... own research and development of Human Coagulation factor VIII. "We are pleased to receive approval from ... on research and development of Human Coagulation factor VIII." Clinical Trial of Human Prothrombin ...

CSL Behring Signs Agreements With Canadian Blood Services and Hema-Quebec to Supply Life-Saving Therapies

... Humate(R) P (Antihemophilic factor / von Willebrand Factor Complex [Human], Dried, ... stored von Willebrand factor; von Willebrand factor replacement therapies, such as Humate-P(R), Antihemophilic Factor/von Willebrand factor Complex (Human) Dried, Pasteurized; and oral ...

AstraZeneca Completes Enrollment in Two Pivotal Phase III Studies of the Investigational Drug Vandetanib (ZACTIMA(R)) in Non-Small Cell Lung Cancer (NSCLC)

... inhibiting vascular endothelial growth factor receptor 2 (VEGFR2), which blocks the development ... blood supply; and inhibiting the epidermal growth factor receptor (EGFR), which may lead to direct ... al. ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth ...

Oncothyreon's PX-478 is effective in preclinical model of human lung cancer

... a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a Phase 1 trial in ... that inhibits the activity of hypoxia inducible factor (HIF)-1 alpha, a transcription factor that controls the expression of a number of genes ...

Transplanted cells may hold the key to curing hemophilia A, Einstein scientists report

... conventional wisdom regarding which cells produce factor VIII, the crucial clotting protein that is ... hemophilia. Weve known for three decades that factor VIII is produced in the liver, but precisely ... and pathology at Einstein. It was assumed that factor VIII was made by the hepatocytescells that ...

Senesco Technologies Reports on Results of Preclinical Multiple Myeloma Studies

... to further test the ability of Senesco's factor 5A technology to induce apoptosis in tumors. ... as a vehicle for encapsulation and delivery of factor 5A to tumors. SCID (severe combined ... control mice received a nanoparticle without the factor 5A therapy. One of the dosing regimens showed ...

Oncothyreon highlights corporate and clinical objectives for 2008

... a component of a transcription factor that is an important regulator of the tumor ... angiogenesis, such as vascular endothelial growth factor (VEGF). PX-478 is effective when delivered orally ... factor (HIF)-1 alpha, vascular endothelial growth factor (VEGF) and activator protein 1 (AP-1). These ...

CSL Behring Expands Into Middle East Market with Haemate(R) P

... to the region." Perreault added that, while factor VIII and IX concentrate products are widely ... stored von Willebrand factor; von Willebrand factor replacement therapies, such as Haemate-P, Antihemophilic Factor/von Willebrand factor Complex (Human) Dried, Pasteurized; and oral ...

ThromboGenics Presents Results of the Phase I Trial of TB-402 at the Prestigious American Society of Hematology Annual Meeting

... partial inhibition of the blood coagulation factor VIII. Its long half life of approximately three ... long-acting anticoagulant effect based on partial factor VIII inhibition. We are looking forward to ... Atrial fibrillation (AF), which is a strong risk factor for ischemic stroke, is the most common sustained ...

Nastech Enters Into Feasibility Study to Develop a Non-Injectable Dosage Form of Factor IX to Control Bleeding

... to develop an alternative dosage form of factor IX protein which is currently administered by ... partner to evaluate the feasibility of delivering factor IX without an injection," stated Steven C. Quay, ... with hemophilia B, a result of deficiency in the factor IX protein, require a lifetime of frequent ...

'High Q' NIST nanowires may be practical oscillators

... and Technology (NIST) have a mechanical quality factor at least 10 times higher than reported values for ... of commercial quartz crystals. Because a high Q factor indicates a capacity for stable vibrations, the ... thing about these wires is the very high quality factor observed for such a small object, says NIST ...

deCODE genetics Announces Third Quarter 2007 Financial Results

... over future reporting periods. The largest single factor in the period-on-period increase in revenue ... functional biology work identified as a key factor in modulating risk of heart attack. The Phase ... patients and doctors by surprise. The risk factor detected by deCODE MI(TM) is independent of ...

Scientists synthesize memory in yeast cells

... Like a hand on a faucet, the transcription factor will grab onto a specific gene and control how ... exposed to galactose, created a transcription factor that grabbed on to, and thus activated, the ... switched itself on via the very transcription factor it created when it was switched on. The ...

Scientists synthesize memory in yeast cells

... Like a hand on a faucet, the transcription factor will grab onto a specific gene and control how ... exposed to galactose, created a transcription factor that grabbed on to, and thus activated, the ... switched itself on via the very transcription factor it created when it was switched on. The ...

YM BIOSCIENCES ANNOUNCES POSITIVE PRELIMINARY RESULTS FROM PHASE I/II LUNG CANCER TRIAL OF NIMOTUZUMAB COMBINED WITH RADIATION

... antibody that targets the epidermal growth factor receptor (EGFR). "While preliminary, these ... antibody that targets the epidermal growth factor receptor (EGFR). To date nimotuzumab has ... that targets the epidermal growth factor receptor (EGFR) and is approved in several ...
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(Date:7/11/2014)... were many fires burning in eastern New South Wales, ... 11. , At 03:35 UTC on July 11 (12:35 ... Aqua passed over eastern New South Wales (NSW), the ... visible image of the region and spotted smoke (light ... MODIS,s thermal bands, are outlined in red. , The ...
(Date:7/11/2014)... Cell scientists have set a "mouse TRAP" to capture ... a recent study published in the Journal of ... a technique called TRAP to extract cellular and genetic ... by scientists at the Rockefeller Institute for Medical Research ... the protein-making machinery, or ribosomes, of the cell type ...
(Date:7/11/2014)... from the Max Planck Institute for Medical Research in ... understanding photosynthesis, the process by which the Earth first ... and which is therefore crucial for all higher forms ... the first direct visualization of a crucial event in ... specific protein complex, photosystem II, splits water into hydrogen ...
Breaking Biology News(10 mins):A first direct glimpse of photosynthesis in action 2
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